"HTML description of Job Description" . . "Source"@en . "text/turtle" . "type" . . "Title"@en . "application/pdf" . . . . . . "value" . . . "Job Description" . _:N0e79c8ae50224aa09c4f6a7fd1430e8d . . . """Oxford Anatomy & Physiology ranked #1 in QS World Rankings by subject 2017, 2018, 2020, 2021, 2022, 2023 and 2024 Job description and Selection Criteria Job title Postdoctoral Research Scientist - Organogenesis Division Medical Sciences Division Department Physiology, Anatomy & Genetics Location Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, Parks Road, Oxford, OX1 3QU Grade and salary Grade 7: £37,524 - £45,763 per annum Hours Full time Contract type Fixed-term for 18 months Reporting to Dame Professor Molly Stevens Vacancy reference AV24041 HRIS: 175283 Additional information While this is a full-time role, we welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements. Research topic Design of innovative biomaterials and techniques for regenerative medicine Principal Investigator / supervisor Dame Prof Molly Stevens Project team Stevens Group Project web site Funding partner Recent publications https://www.dpag.ox.ac.uk/research/stevens-group https://www.stevensgroup.org The funds supporting this project are provided by a portfolio of research grants led by Prof Stevens. K. I. Ritzau-Reid, S. J. P. Callens, R. Xie, M. Cihova, D. Reumann, C. L. Grigsby, L. Prados-Martin, R. Wang, A. C. Moore, J. P. K. Armstrong, J. A. Knoblich, M. M. Stevens. “Microfibrous scaffolds guide stem cell lumenogenesis and brain organoid engineering.” Advanced Materials. 2023. DOI: 10.1002/adma.202300305. R. Xie, Y. Cao, R. Sun, R. Wang, A. Morgan, J. Kim, S. J. P. Callens, K. Xie, J. Zou, J. Lin, K. Zhou, X. Lu, M. M. Stevens. “Magnetically driven formation of 3D freestanding soft bioscaffolds.” Science Advances. 2024. DOI: 10.1126/sciadv.adl1549. V. Lalone, A. Aizenshtadt, J. Goertz, F. S. Skottvoll, M. Barbero Mota, J. You, X. Zhao, H. E. Berg, J. Stokowiec, M. Yu, A. Schwendeman, H. Scholz, S. R. Wilson, S. Krauss, M. M. Stevens. “Quantitative chemometric phenotyping of three dimensional liver organoids by Raman spectral imaging (qRamanomics).” Cell Reports Methods. 2023. 3(4):100440. The role We are seeking to appoint a Postdoctoral Research Scientist to join Prof Molly Stevens’s lab at the Kavli Institute for Nanoscience Discovery. The Stevens Group is based at the Department of Physiology Anatomy and Genetics and is also part of the Institute of Biomedical Engineering. The post-holder will develop cutting-edge imaging, spectroscopy and omics capabilities to develop organ-on-a-chip monitoring tools. The post will liaise closely with researchers working on tissue engineering applications, nanotechnology, optics, and machine learning to develop a high-throughput and targeted imaging workflow for analysis of omics and chemometric markers. This post will apply techniques to organoids and cell cultures, and explore overlapping datasets to better understand correlations across dimensions. This multi-disciplinary research requires knowledge of bioengineering, molecular biology, or bioinformatics. The post-holder will be active within a vibrant and multidisciplinary environment comprising multiple research strands in fundamental and applied bionanoscience. Based at Professor Molly Stevens’ group, the post will involve collaborations with other internationally recognised biomaterials and nanomaterials research groups. The Stevens Group has received numerous awards for outstanding biomaterials related research (www.stevensgroup.org) and comprises a diverse and multidisciplinary group of postdoctoral researchers and postgraduate students. We are looking for a talented scientist who is a confident self-starter and a collaborative team member with impeccable work ethics. Responsibilities            Develop tools and techniques to investigate organoid development and drug metabolism to advance the technology towards a drug-screening platform. Develop fluorescent image-based transcriptomic workflows to investigate the development of organoids in organ-on-a-chip platforms and develop protocols that can be translated to a variety of applications. Use state-of-the-art cell-based, biochemical assays and materials-based characterisation techniques to analyse the (stem) cell phenotypes and functionality. Monitor and quantify cellular response using biochemical characterisation techniques and imaging methods (e.g. fixed and live cell/high content imaging). Help the other research staff in the daily management of the group laboratories. Liaise with the other research staff and students working in broad areas of relevance to the research project and partner institutions. Manage own academic research and administrative activities taking initiative in planning own research. This involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines. Adapt existing and develop new scientific techniques and experimental protocols. Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. Contribute ideas for research projects across the group. Develop ideas for securing research funding, and present detailed research proposals to Prof Stevens, management team and senior researchers. 2      Collaborate in the preparation of scientific reports and journal articles and prepare material for presentation in oral and poster formats. Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques. Represent the research group at external meetings/seminars, either with other members of the group or alone, for example by attending progress and management meetings as required and networking with the other research groups. Undertake instruction of PhD, masters and undergraduate students, as agreed. Prepare and deliver a small number of lectures and mark assessments, as agreed. Other Duties      Participate in a regular Annual Review. Undertake any necessary training identified and continuing professional development in order to stay up-to-date professionally including annual Information Governance training. Comply with Health and safety regulations. Comply with the policies and procedures set out in the Handbook for University Support staff (or) Academic-Related staff. Any other duties that may be required from time to time commensurate with the grade of the job. This job description should be regarded only as a guide to the duties required and is not intended to be definitive. It may be reviewed in the light of a change in circumstances following consultation with the post holder. The Job Description does not form part of the contract. Please note that the appointment of the successful candidate will be subject to standard compulsory preemployment screening, such as right to work checks. Selection criteria Essential selection criteria           Hold, or be near to completion of, a PhD/DPhil in bioengineering, chemistry, biophysics, biology or related field. Experience in microfluidic platforms for organ-on-a-chip models. Experience in (stem) cell culture, passaging, characterisation, maintenance and handling. Experience in using a wide range of standard biochemical assays and imaging equipment for characterising and monitoring cell populations and statistical modelling. Experience in Raman microspectroscopy and/or fluorescence image-based transcriptomics. Experience in appropriate data and image analysis techniques including statistical analysis. Previous experience of contributing to publications/presentations, with a proven track record of first author publications in peer reviewed journals. Excellent communication skills, including the ability to write for publication, present research proposals and results, and represent the research group at meetings. Ability to manage own academic research and associated activities. Commitment to engaging with, and promoting awareness of, equality, diversity and inclusion and embedding these into your work. Desirable selection criteria     An interest in clinical translation of science. Experience with entrepreneurial activities or intellectual property is a plus. Experience in hyperspectral data analysis, specifically related to disease diagnostics applications. Knowledge of point-of-care diagnostics. Experience working with patient samples. 3    Experience working in a multidisciplinary research environment. Experience of independently managing a discrete area of a research project. Experience of actively collaborating in the development of research funding applications. Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows:  Lone Working  Work in hot or cold environments  Driving on University business  Working with Ionising Radiation  Regular manual handling  Working with category 3b or 4 lasers (laser safety class)  Work with any substance which has any of the following pictograms on their MSDS: Additional security pre-employment checks This job includes duties that will require additional security pre-employment checks:  A satisfactory basic Disclosure and Barring Service check  University security screening (eg identity checks) 4 About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spinouts, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. The Department of Physiology, Anatomy and Genetics Oxford Anatomy and Physiology ranked #1 in the QS World University Rankings by subject 2017, 2018, 2020 2021, 2022, 2023 and 2024. Our mission is empowering discovery in the physiological sciences to improve health and educate the next generation of doctors and biomedical scientists. For more information, please visit www.dpag.ox.ac.uk 5 The Department of Physiology, Anatomy and Genetics holds a silver Athena Swan award to recognise advancement of gender equality: representation, progression and success for all. The Department is a large pre-clinical department within the Medical Sciences Division, with ca. 500 staff and students. It has a world-class reputation in both its research and teaching. The Department was part of the University of Oxford’s Biological Sciences submission to the Research Excellence Framework 2021 that was rated top for its world-leading research. Moreover, Oxford’s Anatomy and Physiology has been ranked number one in the QS World University Rankings for the past five years. Please see the 2022/2023 annual report: https://www.dpag.ox.ac.uk/news/annual-report-2022-2023 Information about faculty in the Department Professor David Paterson FRSNZ is the Head of Department. There are five named Professors: the Dr Lee’s Professor of Anatomy (vacant) the Waynflete Professor of Physiology (Professor Gero Miesenböck, FRS FMedSci), the BHF Professor of Regenerative Medicine, Development and Reproduction (Professor Paul Riley, FMedSci), the Krebs Chair in Physiological Metabolism (vacant) and the John Black Professor of Bionanoscience (Professor Dame Molly Stevens, FREng, FRS). Other appointments include four Research Professors (Professor Dame Frances Ashcroft, FRS; Emeritus Professor Dame Kay Davies CBE, FRS FMedSci; Professor Scott Waddell FMedSci; Professor Anant Parekh FMedSc FRS), one Wellcome Trust Principal Research Fellow (Professor Andrew King, FMedSci FRS), 13 further full professors and 15 associate professors. There are approximately 175 academic-related research staff supported by external grants and over 100 graduate students registered for higher degrees in the Department. The teaching and the research activities of the department are supported by teams of professional services and technical staff. Research Centres/Institutes and research themes The Department has a distinctive, forward-looking, and integrative biomedical research programme organised into four research Centres with a presence in two research institutes https://www.dpag.ox.ac.uk/. We also have strong cross-cutting themes in cardiac sciences, cell physiology, development and cell biology, functional genomics, metabolism and endocrinology, and neuroscience, which map on to the research centres. These include the Centre for Integrative Neuroscience (Director: Professor A King FRS), Centre for Neural Circuits and Behaviour (Director: Professor G Miesenboeck FRS), Centre for Cellular & Molecular Neurobiology (Emeritus Professor Dame Kay Davies FRS and Professor Dame Frances Ashcroft FRS), Centre for Integrative Physiology (Professor A Parekh FRS)/the Burdon Sanderson Cardiac Science Centre (Director: Professor Manuela Zaccolo FRSB). The Institute for Developmental and Regenerative Medicine (IDRM: Director Professor Paul Riley FMedsci) and the new Kavli Institute for Nanoscience Discovery, which is directly opposite the Sherrington building. https://kavlifoundation.org/news/meet-new-kavli-institute-nanoscience-discovery-university-oxford The Research Centres and thematic areas bring together researchers who address a range of fundamental issues in the biosciences at molecular, cellular, tissue and systems levels of organisation. https://www.dpag.ox.ac.uk/centres For more information, please visit www.dpag.ox.ac.uk The Kavli Institute for Nanoscience Discovery (Kavli INsD) “Where the physical sciences are brought into the cell” Leading scientific discovery into the most basic unit of life - the cell - the Kavli Institute for Nanoscience Discovery (Kavli INsD) is located at the heart of Oxford University’s science area and was inaugurated in March 2021. With over 30 faculty and 450 research staff and graduate students, world leading teams collaborate from multiple departments (biochemistry, cell biology, chemistry, physics, physiology, psychiatry, clinical neurosciences and engineering) to contribute to global health. 6 By bringing multiple disciplines together under the same roof to advance scientific research the Kavli INsD creates an environment that encourages the cross-pollination of ideas and inter-disciplinary cooperation. The Institute comes together to work on global health challenges and benefits from the close proximity of the scientific departments as well as advanced imaging facilities and state-of-the-art-instrumentation. As the first Director of Kavli INsD Professor Dame Carol Robinson and the research teams are creating a culture that is both bold and respectful. The University of Oxford’s, Kavli Institute for Nanoscience Discovery is the U.S based Kavli Foundation’s 20th institute. The foundation, established in the year 2000 by Fred Kavli, has a mission “to advance science for the benefit of humanity”. Research institutes in the fields of nanoscience, astrophysics, neuroscience, and theoretical physics have been endowed by the foundation which also supports programs that strengthen the connection between science and society. Learn more at kavlifoundation.org Research support facilities The Department has shared state-of-the-art facilities for a wide range of applications, such as a histology service, DNA/RNA services (rapid and supportive access to microRNA,RNASeq, CHIPSeq, etc.), confocal and other high resolution imaging equipment as well as a Transmission Electron Microscope. Proteomics facilities include MALDI-TOF/TOF and Ion Trap LCMS/MS systems, and there are extensive magnetic resonance spectroscopy (MRS) and imaging (MRI) facilities for in vivo rodent and clinical investigations, including hyperpolarised technologies. The Department also provides central support in photography, digital imaging, and poster printing as well as a high-quality mechanical workshop. A dedicated research support team helps with grant applications and awards, and data storage and computation facilities. The department is supported by a dedicated IT team. Teaching The main teaching responsibility of the Department is for pre-clinical Medicine students and those reading Biomedical Sciences. There are also contributions to teaching in Biochemistry, Biological Sciences, Human Sciences, Physics, and a graduate Neuroscience MSc programme. In Oxford, Medicine students take a three-year preclinical course before proceeding to clinical training (a further three years). The first five terms of the three-year pre-clinical course provide broad training in all aspects of medical science (leading to the 1st BM qualification). Both pre-clinical Medicine and Biomedical Sciences students spend the last four terms of their course studying for a BA degree, selecting two Advanced Options from a choice of ten, ranging from systems physiology and neuroscience to cellular and molecular science. Both cohorts also undertake an experimental project, which forms one paper in their final examination; these projects are supervised by members of the academic staff. The Department also contributes some preclinical teaching to the first part of the Graduate entry Medicine course. 7 Equality, Diversity and Inclusion in DPAG The Department of Physiology, Anatomy and Genetics (DPAG) is committed to promoting a diverse and inclusive community. We have an active Equality, Diversity, and Inclusion (EDI) committee and are pro-active in promoting race equality. We hold an Athena SWAN silver award in recognition of our efforts to introduce organisational and cultural practices, which promote gender equality and create a better working environment for all. The Department promotes family-friendly policies and supports flexible working arrangements where possible. The University offers 450 nursery places for staff and students at five dedicated University nurseries and a network of local community nurseries. We will be happy to provide you with information about nurseries and schools in Oxford upon request. We encourage applications from suitably qualified, experienced, and eligible candidates regardless of sex, race, disability, age, sexual orientation, transgender status, religion or belief, marital status, or pregnancy and maternity. We embrace our differences, and you are very welcome at DPAG, without the need to hide any part of who you are. Applications are particularly welcome from women and black and minority ethnic heritage candidates, who are under-represented in academic posts in Oxford. To learn more about EDI in DPAG, visit our website: https://www.dpag.ox.ac.uk/work-with-us/equalitydiversity-inclusion For more information about the University’s family friendly benefits, please also see https://hr.admin.ox.ac.uk/information-for-parents-and-carers Potential applicants may email heidi.de-wet@dpag.ox.ac.uk and/or sally.vine@dpag.ox.ac.uk to discuss any aspect of EDI in DPAG. The Medical Sciences Division The Medical Sciences Division is an internationally recognized centre of excellence for biomedical and clinical research and teaching. We are the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: www.medsci.ox.ac.uk 8 How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application, you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs Non-technical questions about this job should be addressed to the recruiting department directly at hr@dpag.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. 9 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/jobapplicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/theejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of Opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 10 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependants. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. Oxford Research Staff Society (OxRSS) A society run by and for Oxford University research staff. It offers researchers a range of social and professional networking opportunities. Membership is free, and all researchers employed by Oxford University are welcome to join. Subscribe at researchstaff-subscribe@maillist.ox.ac.uk to join the mailing list to find out about upcoming events and other information for researchers, or contact the committee on committee@oxrss.ox.ac.uk. For more information, see www.ox.ac.uk/oxrss, Twitter @ResStaffOxford, and Facebook www.facebook.com/oxrss. 11 """^^ . . . "application/xhtml+xml" . "in dataset" . "application/rdf+xml" . . "text/plain" . "Description of Job Description" . . . _:N0e79c8ae50224aa09c4f6a7fd1430e8d . . "Turtle description of Job Description" . "RDF/XML description of Job Description" . "Format"@en . "Notation3 description of Job Description" . "NTriples description of Job Description" . "text/n3" . "Document" . . . . "Past vacancies at the University of Oxford" . "text/html" .