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Postdoctoral Researcher - DNA Damage Signalling and Repair

Applications for this vacancy closed on 1 December 2017 at 12:00PM
Applications are invited for a postdoctoral research position within the
Genome Stability and Tumourigenesis Group led by Professor Madalena Tarsounas.
The primary goal of the Genome Stability and Tumourigenesis Group is to
investigate how tumour cells lacking BRCA1 or BRCA2 tumour suppressors develop
tolerance to endogenous replication stress and how this, in turn, sustains
cell proliferation and tumour growth.



We are looking for a highly motivated postdoctoral researcher interested in
investigating how defects in replication and checkpoint signalling lead to
chromosome missegregation during mitosis in cells lacking BRCA2. The
successful candidate will carry out research using mass spectrometry as a
discovery tool, combined with hypothesis-driven cell biological and
biochemical approaches to identify activities other than MUS81 that promote
progression of BRCA2-deficient cells through mitosis and prevent lethal loss
of chromosome integrity in cancer cells carrying BRCA2 mutations.



You will hold, or be working towards, a PhD in cell biology, molecular
biology, genetics or biochemistry (or related area of research) and will be
highly motivated and committed to achieve clear career goals. A proven high-
level of technical competence in standard cell and molecular biology
techniques is essential. You will also have strong research track record in
DNA damage signalling/repair and a good publication record with a minimum of
one first-author publication in a peer-review journal.



This is a full-time post and is offered for 3 years in the first instance with
the possibility of extension.



All applicants must complete a short online application form and upload a CV
with publication list, a supporting statement and a reprint of their best
article.



The closing date for applications is 12.00 noon on 1 December 2017.



Please note that the University of Oxford's retirement policy has changed.
With effect from 1 October 2017, all employees at Grade 8 and above have a
retirement age of the 30 September before the 69th birthday. All employees at
Grades 1-7 do not have a set retirement age. Further details are available
here: https://www.ox.ac.uk/about/jobs/preemploymentscreening.

dc:spatial
CRUK/MRC Oxford Institute for Radiation Oncology, Old Road Campus Research Building, Oxford
Subject
Contact
Formal Organization
oo:organizationPart
vacancy:applicationClosingDate
2017-12-01 12:00:00+00:00
vacancy:applicationOpeningDate
2017-10-25 09:00:00+01:00
vacancy:furtherParticulars
vacancy:internalApplicationsOnly
False
vacancy:salary
type
comment
Applications are invited for a postdoctoral research position within the
Genome Stability and Tumourigenesis Group led by Professor Madalena Tarsounas.
The primary goal of the Genome Stability and Tumourigenesis Group is to
investigate how tumour cells lacking BRCA1 or BRCA2 tumour suppressors develop
tolerance to endogenous replication stress and how this, in turn, sustains
cell proliferation and tumour growth.



We are looking for a highly motivated postdoctoral researcher interested in
investigating how defects in replication and checkpoint signalling lead to
chromosome missegregation during mitosis in cells lacking BRCA2. The
successful candidate will carry out research using mass spectrometry as a ...

Applications are invited for a postdoctoral research position within the Genome Stability and Tumourigenesis Group led by Professor Madalena Tarsounas. The primary goal of the Genome Stability and Tumourigenesis Group is to investigate how tumour cells lacking BRCA1 or BRCA2 tumour suppressors develop tolerance to endogenous replication stress and how this, in turn, sustains cell proliferation and tumour growth.


We are looking for a highly motivated postdoctoral researcher interested in investigating how defects in replication and checkpoint signalling lead to chromosome missegregation during mitosis in cells lacking BRCA2. The successful candidate will carry out research using mass spectrometry as a ...

label
Postdoctoral Researcher - DNA Damage Signalling and Repair
notation
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