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About the role

 

This is an exciting opportunity for a postdoctoral researcher to work alongside world renowned scientists at the Oxford Vaccine Group (OVG) in a team led by Professor Sir Andrew Pollard and Dr Young Chan Kim.

 

The successful candidate will take responsibility for an exciting programme of work which aims to accelerate the development of a new vaccine against alphaviruses. The project aims to develop new adenoviral vectored vaccines and mRNA vaccines against alphaviruses, such as Chikungunya virus and to assess these in pre-clinical models. The ideal vaccine candidate selected from pre-clinical studies will move on to the clinical testing. The postholder should have a PhD, with some relevant research experience, sufficient knowledge of pre-clinical and/or clinical research and of immunological methods and virology techniques to work within established research programmes. You must be an enthusiastic and self-motivated scientist with the ability to manage the day-to-day running of a research project including troubleshooting and a capacity to deliver high quality research outputs.

 

This position is offered full-time on a fixed-term contract initially for two years with the possibility to extend provided further external funding is available.

 

This role meets the criteria for a UK Skilled Worker visa.

 

Application Process 

 

You will be required to upload a CV and Supporting Statement as part of your online application. The Supporting Statement should include a cover letter and should also clearly describe how you meet each of the selection criteria listed in the job description. Click here for information and advice on writing an effective Supporting Statement.

 

To discuss the post in more detail, please contact Dr Young Chan Kim, the Sir Henry Wellcome Fellow, using the contact details below.

 

Only online applications received before 12.00 midday on Friday 1 December 2023 will be considered. Interviews will be held as soon as possible thereafter.
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The successful candidate will take responsibility for an exciting programme of work which aims to accelerate the development of a new vaccine against alphaviruses. The project aims to develop new adenoviral vectored vaccines and mRNA vaccines against alphaviruses, such as Chikungunya virus and to assess these in pre-clinical models. The ideal vaccine candidate selected from pre- clinical studies will move on to the clinical testing. The postholder should have a PhD, with some relevant research experience, sufficient knowledge of pre-clinical and/or clinical research and of immunological methods and virology techniques to work within established research programmes. You must be an enthusiastic and self-motivated scientist with the ability to manage the day-to-day running of a research project including troubleshooting and a capacity to deliver high quality research outputs. This position is offered full-time on a fixed-term contract initially for two years with the possibility to extend provided further external funding is available. This role meets the criteria for a UK Skilled Worker visa. **Application Process ** You will be required to upload a CV and Supporting Statement as part of your online application. The Supporting Statement should include a cover letter and should also clearly describe how you meet each of the selection criteria listed in the job description. Click here for information and advice on writing an effective Supporting Statement. To discuss the post in more detail, please contact Dr Young Chan Kim, the Sir Henry Wellcome Fellow, using the contact details below. Only online applications received before 12.00 midday on Friday 1 December 2023 will be considered. Interviews will be held as soon as possible thereafter. """ . . . . _:N5a852000f9a14a66bb771cd5f1ce59dd . . . . . . . . "WTC Clinical Vaccinology and Tropical Medicine" . 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"""_________________________________________________________________________ Job description and selection criteria Job title Postdoctoral Research Scientist Division Medical Sciences Department Paediatrics Location Oxford Vaccine group, Centre for Clinical Vaccinology and Tropical Medicine (CCVTM), Churchill Hospital, Oxford OX3 7LA Grade and salary Grade 7: £36,024- £44,263 per annum (with a discretionary range to £48,350 per annum) Hours Full time Contract type Fixed-term contract for two years in the first instance with possibility of further extension depending on the availability of funding. Reporting to Professor Sir Andrew Pollard / Dr Young Chan Kim Vacancy reference 168702 Additional information This role meets the criteria for a UK Skilled Worker visa Research topic Vaccine development against alphaviruses Principal Investigator Professor Andrew Pollard / Dr Young Chan Kim / supervisor Project team Oxford Vaccine Group Project web site www.ovg.ox.ac.uk and www.paediatrics.ox.ac.uk/ovg Funding partner The funds supporting this research project are provided by the SBRI Innovate UK. The role The Oxford Vaccine Group directed by Professor Sir Andrew Pollard led the rapid clinical development of vaccines against COVID-19 in the pandemic and has made major contributions to knowledge supporting the development of vaccines, understanding of infectious diseases, and influencing national and global policy on immunisation over three decades. We are seeking to recruit a Postdoctoral Research Scientist to work on an exciting research project focused on viral immunology and vaccine development against alphaviruses. The project is based at the Oxford Vaccine Group, and you will work under Professor Sir Andrew Pollard and Dr Young Chan Kim. The project aims to develop new adenoviral vectored vaccines and mRNA vaccines against alphaviruses, such as Chikungunya virus and to assess these in pre-clinical models. This role presents an excellent opportunity for an enthusiastic and self-motivated scientist with an interest in viral pathogens to work on a range of possible projects. The ideal candidate should possess previous laboratory experience in general virological techniques, immunological assays, demonstrate good organizational and communication skills, and be proficient in teamwork. Previous experience in general virology techniques and handling cell culture is essential. The research involves both humoral and cellular immunology techniques carried out with blood samples from animal or human. These techniques include the virus neutralisation assay (PRNT), ELISA and ELISPOT. Some of the work will require category 3 level work and necessary training will be provided. Your responsibilities will also involve providing timely updates to the team and the project manager. This will facilitate tracking progress against objectives and compiling project reports in a timely manner for efficient running of the projects. You will work closely with Dr Young Chan Kim and his team of postdoctoral scientists and research assistants and should be highly motivated, efficient, well-organised, pro-active, and able to take initiative and to work autonomously in a fast-paced, scientific environment. You will be highly organized, with proven experience in a laboratory environment. You will have good interpersonal skills and be able to interact productively and accurately with other team members. If you are interested in this position and have the skills and experience, we are looking for, please apply online. You will be required to upload a CV and supporting statement. The supporting statement should describe how you fit the criteria for the role, including your motivation and curiosity about the research project. Informal inquiries about the position can be sent to Dr Young Chan Kim (young.kim@wolfson.ox.ac.uk). Responsibilities • Manage own academic research and administrative activities. This involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines • Adapt existing and develop new scientific techniques and experimental protocols • Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate Department of Paediatrics, Postdoctoral Research Scientist, Job Description 2 • Contribute ideas for new research projects • Develop ideas for generating research income, and present detailed research proposals to senior researchers • Collaborate in the preparation of scientific reports and journal articles and occasionally present papers and posters • Use specialist scientific equipment in a laboratory environment • Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques • Represent the research group at external meetings/seminars, either with other members of the group or alone • Carry out collaborative projects with colleagues in partner institutions, and research groups Selection criteria Essential • Hold a relevant PhD/DPhil (or near completion) in subjects related to medical science together with relevant experience • Practical experience in general virology techniques and cell biology. • Knowledge of Virology and Immunology. • Ability to communicate well in writing and in oral presentations • Ability to work as part of a team, and contribute to a collaborative and friendly work environment • Ability to keep accurate lab records, analyse data independently and communicate experimental data effectively to scientists from a range of disciplines • Excellent interpersonal and communication skills with the ability to interact equally effectively with senior academic staff, researchers and support staff • Clearly explained motivation and curiosity about the specific research project Desirable • Experience of independently managing a discrete area of a research project • Track record of publication in high-quality peer reviewed journals Department of Paediatrics, Postdoctoral Research Scientist, Job Description 3 • Basic skills in virology techniques and working with containment level 3 pathogens • Appreciation of key research questions in the field Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • Working with infectious pathogens (hazard group 2/3) - Hazard Group 3 pathogens • Working with blood, human products and human tissues • Work with allergens, e.g. laboratory animals, pollen, dust, fish or insects etc. • Work with any substance which has any of the following pictograms on their MSDS: Additional security pre-employment checks This job includes duties that will require additional security pre-employment checks: • Enhanced Level Screening as this role includes conducting research involving animals (or working closely with such research). • This role requires a research passport. The department will support the successful candidate in obtaining this where required and appropriate. • A satisfactory basic Disclosure and Barring Service check due to working with sensitive personal data. • University security screening (e.g. identity checks) Department of Paediatrics, Postdoctoral Research Scientist, Job Description 4 About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Oxford Vaccine Group The Oxford Vaccine Group (OVG) is led by Andrew J Pollard, Professor of Paediatric Infection and Immunity. Staff re based within a purpose built centre on the Churchill Hospital site and form part of the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM). The aim of OVG is to co-ordinate expertise in the study of microbial diseases and the immune response to microbes, in order to facilitate research on the development and implementation of vaccines. This may include new, improved or combined vaccines for the adult and paediatric population. There is currently a large focus on delivering the COVID-19 vaccine trials. Core group members include two Consultants in Vaccinology, a Director of Clinical Trials, a Senior Clinical Trials Manager, adult and paediatric clinical research fellows, adult and paediatric research nurses, project managers, QA manager, IT manager, and an administration team. The Infection and Immunity Laboratory includes post doctorate scientists, research assistants and DPhil students. Wider group members include professionals from a range of specialities including immunologists, microbiologists, statisticians, a community paediatrician, the local Health Protection team and a bioethicist. Recent studies carried out by the group include: • • • • • COVID vaccine trials (Phase 1, 2 and 3), Heterologous regimens and booster studies Vaccines against RSV Pneumococcal nasopharyngeal carriage epidemiology Meningococcal B vaccine development and evaluation Development of a typhoid challenge model More information about OVG may be found at the website: http://www.ovg.ox.ac.uk Department of Paediatrics, Postdoctoral Research Scientist, Job Description 5 Department of Paediatrics The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. Our work spans from early proof-of concept fundamental science, all the way up to its application in clinical settings. We continue to shape the landscape of medical science through positively impacting the lives of millions of children from our global research programmes, academic resources, and commitment to success. Our broad research base positions the department in a pivotal role and subsequently a world leader in child health. With research facilitates in the UK and abroad, we work on a global scale, building a paediatric network in the medical science community. We are committed to inform and inspire external audiences worldwide through our public engagement and outreach activities. In 2021, we successfully administered a grant value of £130,895,28 obtained through 168 projects. Our strong relationship with funding bodies have also been a contributor to the successes and milestones in children’s health research. With strong support from the Wellcome Trust, NIH, Cancer Research UK, UKRI, MDUK, Bill & Melinda Gates Foundation, Academy of Medical Sciences and the NIHR, we have employed 360+ staff, researchers, and students. These figures continue to grow as we expand our activities to overcome the multitude of challenges within children’s research health. For more information please visit: http://www.paediatrics.ox.ac.uk/ The Department of Paediatrics holds a silver Athena Swan award to recognise advancement of gender equality: representation, progression and success for all. Medical Sciences Division We are an internationally recognized centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: http://www.medsci.ox.ac.uk/ Department of Paediatrics, Postdoctoral Research Scientist, Job Description 6 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting https://staff.web.ox.ac.uk/recruitment-support-faqs advice is available at: Non-technical questions about this job should be addressed to the recruiting department directly at recruitment@paediatrics.ox.ac.uk or using the contact details in the online advertisement. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our e-recruitment system to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. 7 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 8 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. 9 """^^ . . "License"@en . . . "email"@en . 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