We are seeking to appoint an enthusiastic and highly motivated graduate or postdoctoral research assistant to join the Mitotic Progression group headed by Prof Ulrike Gruneberg. The Gruneberg lab studies the mechanisms safeguarding mammalian genome stability during cell division in the context of cancer.

 

The successful candidate will focus on the mechanisms ensuring faithful chromosome segregation, with the goal of elucidating how kinases and phosphatases coordinate error correction and spindle checkpoint signalling during this process. The work will involve a combination of biochemical analysis of protein complexes as well as cutting edge fixed and live cell imaging. Applicants are expected to be highly motivated, organised and reliable, and to be able to work independently as well as in a team.

 

Applicants should possess or be close to completing a degree or PhD in Biochemistry or Molecular Biology, have a demonstrable interest or experience in the cell cycle or chromosome biology field, and will have a competitive publication record (taking career stage into account). Proven experience in molecular biology and recombinant protein production, as well as demonstrable experience with the genetic manipulation of mammalian cells and the generation of stable cell lines are essential criteria for the post. Experience with immunofluorescence and live cell imaging analysis as well as mass spectrometry would be advantageous.

 

Applicants who hold a BSc/MSc degree in a relevant subject will be considered for a Graduate Research Assistant position that will be offered at Grade 6: £32,332 - £38,205 p.a. with reasonable adjustments in the job responsibilities.

 

This is a fixed-term appointment available for 3 years. If you are interested in this role, and have the skills and experience we are looking for, please apply online. You will be required to upload a CV and supporting statement as part of your online application.

 

Informal inquiries about the position can be sent to Prof. Ulrike Gruneberg (Ulrike.gruneberg@path.ox.ac.uk).

 

The closing date for applications is 12.00 midday on 15 December 2023. Interviews will be held as soon as possible thereafter.