"Agent" . "telephone"@en . "image" . . . "text/n3" . "Format"@en . . . . "has max currency value (1..1)"@en . "Henry Wellcome Building For Particle Imaging (OPIC)" . "License"@en . """Job title Postdoctoral Research Scientist Division Medical Sciences Department Nuffield Department of Medicine Location CAMS Oxford Institute, Roosevelt Drive, Old Road Campus, Oxford, OX3 7BN Grade and salary Grade 7: Salary in range £36,024 - £44,263 per annum (pro rata) Hours Full time Contract type Fixed-term contract until 31 December 2026 Reporting to Juthathip Mongkolsapaya, PI and Group Leader Vacancy reference 169823 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship or a Global Talent Visa under UK Visas and Immigration legislation. Therefore, the Nuffield Department of Medicine welcomes applications from international applicants who require a visa. About us • • • What we offer https://hr.admin.ox.ac.uk/staff-benefits • An excellent contributory pension scheme • 38 days annual leave • A comprehensive range of childcare services • Family leave schemes • Cycle loan scheme • Discounted bus travel and Season Ticket travel loans • Membership to a variety of social and sports clubs • A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - www.camsoxford.ox.ac.uk The role Applications are invited for a postdoctoral research scientist to join an exciting research project on viral immunology, particularly infections with Flavivirus and Coronavirus in the laboratory of Professor Gavin Screaton and Associate professor Juthathip Mongkolsapaya. Both virus families, especially the members of Coronaviruses, cause a massive healthcare burden. We have considerable experience in the investigation of the immune responses to the viruses and publish well. You will be involved in a broadly-based research program covering a number of aspects of viral immunology, and vaccine development. Your primary responsibilities will include; managing your own academic research in a dynamic and highly collaborative environment of an internationally leading research institute. This involves project management, to co-ordinate multiple aspects of work to meet deadlines. Adapting existing and develop new scientific techniques, and experimental protocols and testing hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. You will contribute ideas for new research projects and collaborate in the preparation of scientific reports, journal articles, and grant application and occasionally present papers and posters. Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques as well as conduct and plan own scientific work. You will benefit from the institute and wider university expertise in immunology, virology, and molecular biology. There will be opportunities to develop new therapeutic materials and vaccine development in infectious diseases. You must have a proactive and adaptable approach to work and willingness to collaborate and provide scientific and workplace guidance to research assistants and students. Excellent record keeping, careful methodological work skills and the ability to meet deadlines are essential. You will need to communicate effectively with a range of collaborators, including the COI research groups and contributing groups across Oxford. Responsibilities You will: • • • • • • • • • • • • • • • Generate and characterise human monocloal antinodies to viruses of interest sush as SARSCoV2 and dengue viruses. Generate SARS-CoV2 psuedo viruses based on the new emerging variants. Isolating viruses of interest sush as SARS-CoV2 and dengue viruses from clinical samples. Manage own academic research and administrative activities. This involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines. Adapt existing and develop new scientific techniques and experimental protocols. Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. Contribute ideas for new research projects. Collaborate in the preparation of scientific reports and journal articles and occasionally present papers and posters. Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques. Conduct and plan own scientific work with appropriate supervision. Take initiatives in the planning of research. Direct the work of small research teams. Identify and develop suitable techniques for the collection and analysis of data. Conduct data analysis ensuring the validity and reliability of data at all times. Maintain accurate and complete records of all findings. 1 • • • • • Conduct and plan own scientific work with appropriate supervision. Maintain highly organised and accurate record of experimental work. Actively participate in the research programme of the Group. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Selection criteria Essential • • • • • • • • • • • • • • • • • Hold a relevant PhD/DPhil (or close to completion) in a subject related to antibody responses to viral infection. Experience of working on antibody responses to SARS-CoV2 and dengue virus. Experience in generating human monoclonal antibodies from human activated, memory, and antigen specific B cells, mouse hybridoma cells, and chimera human antibodies. Experience and knowledge of protein and antibodies productions in a mammalian cells and associated functional analysis especially relating to viral infection. Experience of generating SARS-CoV2 psuedo-viruses. Experience of psudo-virus and live virus neutralisation assays. Experience of independently working on SARS-CoV2 and dengue virus in a class 3 suite. Excellent in viral isolation from clinical samples and purification, propagation and relevant virological functional assays. Excellent in molecular biology, particularly in nested-PCR, Gibson reaction, gene editing, and molecular cloning. Experience on computer programes including Microsoft office, SPSS, Prism, Flow Jo, and Snap gene. Experience on VIridot programe to enumerate viral foci. Knowledge of Virology, Immunology, Molecular Biology, and Biochemistry. Knowledge of research methods and statistical procedures. Practical experience within a research environment and / or publication in relevant and referred journals. Ability to manage own academic research and associated activities Ability to contribute ideas for new research projects and research income generation Excellent communication skills, including the ability to write for publication, present research proposals and results, and represent the research group at meetings Desirable • • • • Practical experiences with flow cytometry particularly SARS-CoV2-specific human B cells sorting, protein handling (expression as well as purification on various systems, particularly mammalian systems, and characterisations). Experience of generating infectious virus and mutants using Gibson technique Experience of isolating SARS-CoV2 from clinical samples. Experience of cloning, expressing, and strep-tag affinity purifying SARS-CoV2 Spike protein 2 Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • • • • Lone Working Working with infectious pathogens (hazard group 2/3) - Hazard Group 3 pathogens Working with blood, human products and human tissues Work with any substance which has any of the following pictograms on their MSDS: • Travel outside of Europe or North America on University Business Additional security pre-employment checks This job includes duties that will require additional security pre-employment checks: • • A satisfactory enhanced Disclosure and Barring Service University security screening (eg identity checks) 3 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents. • http://www.ox.ac.uk/about_the_university/jobs/research/ All applications must be received by midday UK time on the closing date stated in the online advertisement Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement 4 The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 5 """^^ . . "GBP" . "application/xhtml+xml" . . . . "7" . _:N52c5a67acd32477781116e0d90838b5d "United Kingdom" . "Henry Wellcome Building For Particle Imaging (OPIC)" . "Grade 7: Salary in range £36,024 - £44,263 per annum (pro rata)" . "building" . "label" . "Estates identifier" . . "Kaitlin Beazley" . "CAMS Oxford Institute" . . "RDF/XML description of Postdoctoral Research Scientist" . . . . 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"""Applications are invited for a postdoctoral research scientist to join an exciting research project on viral immunology, particularly infections with Flavivirus and Coronavirus in the laboratory of Professor Gavin Screaton and Associate Professor Juthathip Mongkolsapaya. Both virus families, especially the members of Coronaviruses, cause a massive healthcare burden. We have considerable experience in the investigation of the immune responses to the viruses and publish well. You will be involved in a broadly-based research program covering a number of aspects of viral immunology, and vaccine development. Your primary responsibilities will include; managing your own academic research in a dynamic and highly collaborative environment of an internationally leading research institute. This involves project management, to co-ordinate multiple aspects of work to meet deadlines. Adapting existing and develop new scientific techniques, and experimental protocols and testing hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. You will contribute ideas for new research projects and collaborate in the preparation of scientific reports, journal articles, and grant application and occasionally present papers and posters. Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques as well as conduct and plan own scientific work. You will benefit from the institute and wider university expertise in immunology, virology, and molecular biology. There will be opportunities to develop new therapeutic materials and vaccine development in infectious diseases. As part of the role you will need to hold a PhD or be close to completion of your PhD in a subject related to antibody responses to viral infection. You must have a proactive and adaptable approach to work and willingness to collaborate and provide scientific and workplace guidance to research assistants and students. Excellent record keeping, careful methodological work skills and the ability to meet deadlines are essential. You will need to communicate effectively with a range of collaborators, including the COI research groups and contributing groups across Oxford. Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a fixed term contract until 31 December 2026 Only applications received before 12 midday on 11 December 2023 will be considered. Please quote **169823** on all correspondence. """ . "CN" . "OpenStreetMap feature identifier" . . . . 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Applications are invited for a postdoctoral research scientist to join an exciting research project on viral immunology, particularly infections with Flavivirus and Coronavirus in the laboratory of Professor Gavin Screaton and Associate Professor Juthathip Mongkolsapaya.

 

Both virus families, especially the members of Coronaviruses, cause a massive healthcare burden. We have considerable experience in the investigation of the immune responses to the viruses and publish well. You will be involved in a broadly-based research program covering a number of aspects of viral immunology, and vaccine development.

 

Your primary responsibilities will include; managing your own academic research in a dynamic and highly collaborative environment of an internationally leading research institute. This involves project management, to co-ordinate multiple aspects of work to meet deadlines. Adapting existing and develop new scientific techniques, and experimental protocols and testing hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate.

 

You will contribute ideas for new research projects and collaborate in the preparation of scientific reports, journal articles, and grant application and occasionally present papers and posters. Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques as well as conduct and plan own scientific work. You will benefit from the institute and wider university expertise in immunology, virology, and molecular biology. There will be opportunities to develop new therapeutic materials and vaccine development in infectious diseases.

 

As part of the role you will need to hold a PhD or be close to completion of your PhD in a subject related to antibody responses to viral infection. You must have a proactive and adaptable approach to work and willingness to collaborate and provide scientific and workplace guidance to research assistants and students. Excellent record keeping, careful methodological work skills and the ability to meet deadlines are essential. You will need to communicate effectively with a range of collaborators, including the COI research groups  and contributing groups across Oxford.

 

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.



This position is offered full time on a fixed term contract until 31 December 2026



Only applications received before 12 midday on 11 December 2023 will be considered. Please quote 169823 on all correspondence.
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