Description of Research Assistant in Functional Genomics of Sepsis
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Research Assistant in Functional Genomics of Sepsis
further particulars: 170243 - Research Assistant in Functional Genomics of Sepsis
based near: Wellcome Trust Centre for Human Genetics
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spatial: Centre for Human Genetics, Henry Wellcome Building for Genomic Medicine, Old Road Campus, Roosevelt Drive, Headington Oxford, OX3 7BN
application opening date: 2024-01-31T09:00:00+00:00
application closing date: 2024-02-21T12:00:00+00:00
subject: research
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comment: Applications are invited for a Research Assistant in Functional Genomics of Sepsis at the University of Oxford. You will be based at the Centre for Human Genetics within the group of Professor Julian Knight, joining an established team with a track record of innovation and high impact research in functional genomics, sepsis and susceptibility to multi-factorial disease. This is an exciting new position funded through a new collaboration with the Danaher corporation and its subsidiary Cepheid. This research is part of the Beacon programme ‘Development and prospective evaluation of point-of-need test for sepsis subtyping based on gene expression using the Cepheid GeneXpert platform’. The programme seeks to advance precision medicine for patients with sepsis by developing a point-of-care test to stratify patients based on their immune response profiles. We aim to use an integrated approach which leverages the host transcriptome, immune profiling, and electronic health records, in combination with the GeneXpert system for mRNA quantification. Our goal is to deliver a precision medicine approach for managing patients with severe infections. The work is highly collaborative with clinical teams, company partners, and expert investigators across the UK, the US, and Sweden. You will facilitate exciting new collaborative links with Danaher, which may involve travel to Sweden (Cepheid) and the United States (Danaher). You will be responsible for managing sample collections from recruited individuals through excellent team communication and record keeping skills. You will be supporting clinical phenotyping and related data management and working closely with the research nurse team and our collaborators in Danaher and Cepheid to ensure samples and data is shared in a timely and appropriate manner, and project milestones are met. You will be working as part of an interdisciplinary team, contribute fully to laboratory meetings and discussion of the aims and objectives of the grou…
contact: Kristina Limbu
type: Vacancy

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170243 - Research Assistant in Functional Genomics of Sepsis
value: Job title Research Assistant in Functional Genomics of Sepsis Division Medical Sciences Department Nuffield Department of Medicine Location Centre for Human Genetics, Old Road Campus, Roosevelt Drive, Headington Oxford, OX3 7BN Grade and salary Grade 6: Salary in range £32,332 - £38,205 per annum (pro rata) Hours Full time Contract type Fixed-term contract until 1 October 2027 Funding is provided by the Danaher Corporation Reporting to Julian Knight, Group Head/ Principal Investigator Vacancy reference 170243 Hybrid working arrangements The successful person will need to work on site for a minimum of 3 days per week Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship or a Global Talent Visa under UK Visas and Immigration legislation. Therefore, the Nuffield Department of Medicine welcomes applications from international applicants who require a visa. About us    What we offer https://hr.admin.ox.ac.uk/staff-benefits  An excellent contributory pension scheme  38 days annual leave  A comprehensive range of childcare services  Family leave schemes  Cycle loan scheme  Discounted bus travel and Season Ticket travel loans  Membership to a variety of social and sports clubs  A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - www.well.ox.ac.uk Research topic Genomics of Sepsis Principal Investigator Professor Julian Knight Project web site https://www.well.ox.ac.uk/research/research-groups/julian-knightgroup Funding partner The funds supporting this research project are provided by the Danaher Corporation Kwok AJ, Allcock A, Ferreira RC, Cano-Gamez E, Smee M, Burnham KL, Zurke Y-X, Emergency Medicine Research Oxford (EMROx), McKechnie S, Mentzer AJ, Monaco C, Udalova I, Hinds CJ, Davenport EE, Todd JA, Knight JC (2023). Neutrophils and emergency granulopoiesis drive immune suppression and an …
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