Postdoctoral Researcher in Neuroimaging
comment: We are looking for a Postdoctoral Researcher in Neuroimaging based within the Wellcome Centre for Integrative Neuroimaging (WIN), reporting to Professor Karla Miller and Associate Professor Ludovica Griffanti. The project is funded by the NIHR Oxford Health BRC Brain Technologies theme, which focuses on the scientific/clinical interface to create and test accurate tools for measuring brain structure and function to improve risk identification, early diagnosis, outcome prediction and treatment targeting. Millions of hospital brain scans are performed globally each year. At the moment, these scans are interpreted by eye. This means the structure and content of the radiology reports is very variable, and even the most expert clinician may not be able to detect subtle changes in this way. In the research setting, we build powerful algorithms that analyse information objectively, compare scans across individuals or over time. However, these tools are mostly designed to analyse homogeneous data from groups of participants in research studies rather than to inform clinical decision making about individual patients based on variable clinical data. The post holder will contribute to the steps needed to deploy such brain-health markers to support individual patient decision making in clinical practice. You will be primarily responsible for the development of methods to obtain comparable measures from scans acquired with different hardware in both clinical and research settings. This will involve i) assessing variability of brain-health markers across hardware and its impact on clinically-relevant outcomes; ii) developing a strategy to minimise non-biological variability in the measures and iii) implement it at the acquisition and/or image processing level. The project is in close collaboration with the University of Manchester, which will also provide access to brain scanners from three major vendors in clinics across the city with the aim of creating a standard output from a…
application closing date: 2024-03-06T12:00:00+00:00
further particulars: Job Description
application opening date: 2024-02-14T09:00:00+00:00
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contact: NDCN HR Recruitment
salary: Standard Grade 8: £45,585 - £54,395 per annum
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Job Description
value: West Wing, Level 6, John Radcliffe Hospital, Oxford, OX3 9DU Web: www.ndcn.ox.ac.uk | Tel: +44(0)1865 234702 | Email: recruitment@ndcn.ox.ac.uk Job title Postdoctoral Researcher in Neuroimaging Division Medical Sciences Division Department Nuffield Department of Clinical Neurosciences (NDCN) Location WIN@FMRIB, John Radcliffe Hospital, Headington, Oxford, OX3 9DU Grade and salary Grade 8: £45,585 - £54,395 per annum Hours Full time Contract type Fixed-term until 31st March 2025 in the first instance Reporting to Prof. Karla Miller and Ludovica Griffanti Vacancy reference 170525 Additional information The post is available from 1st April 2024 Research topic Harmonisation of MRI brain scans Principal Investigator / supervisor Profs. Karla Miller and Ludovica Griffanti Project team WIN Physics, WIN Analysis, NIHR Oxford Health BRC www.ox.ac.uk/ https://www.win.ox.ac.uk/research/physics-research Project web site https://www.win.ox.ac.uk/people/ludovica-griffanti https://oxfordhealthbrc.nihr.ac.uk/research/brain-technologies/ Funding partner The funds supporting this research project are provided by the NIHR Oxford Health Biomedical Research Centre Recent publications Griffanti et al (2022). Adapting UK Biobank imaging for use in a routine memory clinic setting: the Oxford Brain Health Clinic. NeuroImage: Clinical, 36:103273. Bordin…Griffanti (2021). Integrating large-scale neuroimaging research datasets: Harmonisation of white matter hyperintensity measurements across Whitehall and UK Biobank datasets. NeuroImage, 237: 118189. Alfaro-Almagro et al (2018). UK Biobank Brain Imaging: Automated Processing Pipeline and Quality Control for 100,000 subjects. NeuroImage, 166: 400-424. The role The post will be based within the Wellcome Centre for Integrative Neuroimaging (WIN), reporting to Professor Karla Miller and Associate Professor Ludovica Griffanti. The project is funded by the NIHR Oxford Health BRC Brain Technologies theme, which focuses on the scientific/clinical inte…
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