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Postdoctoral Research Assistant in Tumour Biology
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comment: We are seeking an enthusiastic, well-trained and self-motivated Postdoctoral Research Assistant to take a pivotal role in conducting research on cholangiocarcinoma (CCA), based at the John Radcliffe Hospital, University of Oxford. The post holder should have an interest in studying the interaction between normal cholangiocytes (NCCs) and CCA cells in the tumour immune microenvironment, as well as evaluating the effects of epigenetic inhibitors on CCA growth in vitro and in vivo. The post-holder must hold a Ph.D. degree in cancer biology and immunology. You will report to Dr. Shijie Cai and work with limited supervision, utilising molecular cell biology and immunology techniques, along with prior experience in bioinformatics analysis, to successfully achieve the project's objectives. Effective workload management and meeting deadlines are essential skills. You should also be capable of working within a team and be prepared to train postgraduate students and visiting fellow researchers in research techniques for their projects. An strong track record of previous publications and excellent communication skills are required The position is initially fixed for a duration of 12 months, with the potential renewal contingent on satisfactory research project progression. Funding for this position is provided by the Alan Morement Memorial Foundation. Applications for this vacancy are to be made online. For further details, including person specification, please see attached job description. The closing date for applications is 12 noon on Friday 15th March 2024. Interviews to be held 19th March 2024. Committed to equality and valuing diversity.
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value: _________________________________________________________________________ Nuffield Division of Clinical Laboratory Sciences Job Description and Selection Criteria Job title Postdoctoral Research Assistant in Tumour Biology Division Medical Sciences Division Department Nuffield Division of Clinical Laboratory Sciences, RDM Location Level 4, Academic Block, John Radcliffe Hospital Grade and salary Grade 7: £36,024 - £44,263 per annum Hours Full Time Contract type Fixed Term for 12 months. Reporting to Dr Shijie Cai Vacancy reference 171542 Research topic Normal cholangiocyte containment of cholangiocarcinoma through metabolic and transcriptomic regulation Principal Investigator / supervisor Shijie Cai Project team Kerr and Cai Group Project web site https://www.rdm.ox.ac.uk/about/our-divisions/nuffield-division-ofclinical-laboratory-sciences/nuffield-division-of-clinical-laboratorysciences-research/colorectal-clinical-and-pathology-group Funding partner The funds supporting this research project are provided by Alan Morement Memorial Foundation The role We are seeking an enthusiastic, highly-trained and self-motivated Postdoctoral Researcher to take a pivotal role in conducting research on cholangiocarcinoma (CCA). _________________________________________________________________________ Nuffield Division of Clinical Laboratory Sciences CCA is a rare yet highly malignant liver cancer. It does not manifest in isolation but rather co-opts the surrounding stromal fibroblasts, endothelial cells and immune cells to facilitate its growth, invasion and metastasis. Normal cholangiocytes (NCCs) are primarily responsible for the secretion and modification of bile, crucial for digesting fats and the eliminating waste products. Furthermore, NCCs are also important in maintaining the structure and function of the biliary tree, as well as in regulating homeostasis and the inflammatory response to infections. Despite these important functions, the interaction between NCCS and CCA re…

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