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WTC Clinical Vaccinology and Tropical Medicine
Department of Paediatrics, Oxford Vaccine Group, Churchill Hospital, Oxford
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______________________________________________________________________ Job description and selection criteria Job title Sample Management Technician Division Medical Sciences Department Paediatrics Location Oxford Vaccine Group, CCVTM, Churchill Hospital, Oxford Grade and salary Grade 4: £25,138- £28,759 per annum (with a discretionary range to £31,396 per annum) Hours Full time (36.5 hours/week) Contract type Fixed term (12 months) Reporting to Clinical Trials Sample Manager, Suzanne Woodlock Vacancy reference 172048 Additional information Applications are to be made online, please see the advert for the closing date. The role The Oxford Vaccine Group Laboratory, under the direction of Professor Pollard is staffed by 23 research staff including technical, undergraduate, graduate and post-doctoral scientists. The job requires flexibility in working hours, the willingness to travel between freezer storage sites, including potentially some weekend work. Research projects include: • Evaluation of immune responses to vaccines in children and adults • Understanding of the nature of immunological memory • Development of a novel vaccines and pre-clinical studies • Genetics of the immune response to vaccines • Natural and vaccine-induced immunity to Salmonella Typhi • Invasive bacterial infections in South Asia The Oxford Vaccine Group (OVG) is the principle site for the collection of samples from participants enrolled in the clinical trials testing the safety and immunogenicity of the University of Oxford/AstraZeneca COVID-19 vaccine. We are also conducting several Vaccine Taskforce supported trials to assess boosting responses using various different COVID-19 vaccines. Further to our COVID-19 work, we test new and improved vaccines against a range of infectious diseases. Each vaccine trial generates an extensive range of samples that are used for testing vaccine-induced responses. These tests may be conducted within the University of Oxford or at external sites. The samples we generate, store and test are key to our understanding of the immune response following vaccination and the data generated in our trials have the potential to shape public policy and affect public health in the UK and internationally. We are looking for enthusiastic individuals to join our dynamic laboratory team to perform sample management duties for samples from our clinical trials. Responsibilities The principle role is to provide sample management support including for shipments to external laboratories and managing freezer capacity for the Oxford Vaccine Group. • Facilitate research objectives by ensuring the upkeep of sample storage, inventory and shipments. • Working with samples across clinical trials that are currently being stored in cold chain storage at OVG, other University of Oxford buildings and external Bio-centre facilities In Milton Keynes and Osney Mead. • Storage/archiving/checking of study related samples such as serum, plasma, white blood cells, urine, saliva, and stool specimens. • To conduct all laboratory work to the standards expected from Good Clinical and Laboratory Practice (GCLP) and OVG quality management guidelines which will include compliance with Human Tissue Authority (HTA) and Medicines and Healthcare products Regulatory Agency (MHRA) regulations. Training will be provided. • Providing administrative laboratory support in maintaining accurate inventories for all samples. • Work closely with the laboratory logistical administrator, senior laboratory managers and researchers to organize and assess current capacities for freezer storage. • Manoeuvre boxes to organize space to the greatest efficiency and needs of the group. • Assist with locating samples for shipments to collaborators. Including navigating inventory systems and creating inventories using computer programs including Microsoft Excel. • Show good understanding of sample tracking using Microsoft Excel and understanding of study timepoints using study documents. Department of Paediatrics, Sample Management Technician, Job Description 2 • Assist in shipment preparation in locating, picking and aliquoting of samples as necessary. Selection criteria Essential • Minimum passes in GCSE Maths, English and Science or relevant experience. • Able to work as a member of a team and take instruction. • Good written and oral communication skills, excellent attention to detail. • Ability to organise own work and to work independently and with minimum supervision. • Able to follow and understand the importance of standard operating procedures. • Experience in using Microsoft packages such as excel. Good record keeping. • Good troubleshooting skills and willingness to work with samples stored at ultra-low temperatures with appropriate PPE provided. • Willingness to travel to various locations where freezer storage is located. • Willingness to be trained in GCP, HTA and Quality Assurance. • Willingness to be trained in operating -80C freezers and liquid nitrogen-filled cryostores. Desirable • Well-developed understanding of health and safety regulation and procedures. • Interest in science and laboratory work. • Hold a full UK driving license with a car. Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. . If you have previously worked for the University we will also verify key information such as your dates of employment and reason for leaving your previous role with the department/unit where you worked. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: Department of Paediatrics, Sample Management Technician, Job Description 3 • Working with blood, human products and human tissues • Work with any substance which has any of the following pictograms on their MSDS: Additional security pre-employment checks This job includes duties that will require additional security pre-employment checks: • Enhanced Level Screening as this role includes conducting research involving animals (or working closely with such research); or with access to/ knowledge of the location of certain pathogens, toxins, irradiators. • A satisfactory basic Disclosure and Barring Service check due to the nature of this position. • University security screening (e.g. identity checks) Department of Paediatrics, Sample Management Technician, Job Description 4 About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. University of Oxford has recently published their New Ways of Working framework to ensure professional service staff can continue to support the University’s academic mission whilst working on site or remotely. For more information, please visit https://hr.admin.ox.ac.uk/new-ways-of-working Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Oxford Vaccine Group The Oxford Vaccine Group (OVG) is led by Andrew J Pollard, Professor of Paediatric Infection and Immunity. The group are based within a purpose-built centre on the Churchill Hospital site and form part of the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM). The aim of OVG is to co-ordinate expertise in the study of microbial diseases and the immune response to microbes, in order to facilitate research on the development and implementation of vaccines. This may include new, improved or combined vaccines for the adult and paediatric population. There is currently a large focus on delivering the COVID-19 vaccine trials. Core group members include two Consultants in Vaccinology, a Director of Clinical Trials, a Senior Clinical Trials Manager, adult and paediatric clinical research fellows, adult and paediatric research nurses, project managers, QA manager, IT manager, and an administration team. The Infection and Immunity Laboratory includes post doctorate scientists, research assistants and DPhil students. Wider group members include professionals from a range of specialities including immunologists, microbiologists, statisticians, a community paediatrician, the local Health Protection team and a bioethicist. Recent studies carried out by the group include: • • • • • COVID vaccine trials (Phase 1, 2 and 3), Heterologous regimens and booster studies Vaccines against RSV Pneumococcal nasopharyngeal carriage epidemiology Meningococcal B vaccine development and evaluation Development of a typhoid challenge model Department of Paediatrics, Sample Management Technician, Job Description 5 More information about OVG may be found at the website: http://www.ovg.ox.ac.uk Department of Paediatrics The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. Our work spans from early proof-of concept fundamental science, all the way up to its application in clinical settings. We continue to shape the landscape of medical science through positively impacting the lives of millions of children from our global research programmes, academic resources, and commitment to success. Our broad research base positions the department in a pivotal role and subsequently a world leader in child health. With research facilitates in the UK and abroad, we work on a global scale, building a paediatric network in the medical science community. We are committed to inform and inspire external audiences worldwide through our public engagement and outreach activities. In 2021, we successfully administered a grant value of £130,895,28 obtained through 168 projects. Our strong relationship with funding bodies have also been a contributor to the successes and milestones in children’s health research. With strong support from the Wellcome Trust, NIH, Cancer Research UK, UKRI, MDUK, Bill & Melinda Gates Foundation, Academy of Medical Sciences and the NIHR, we have employed 360+ staff, researchers, and students. These figures continue to grow as we expand our activities to overcome the multitude of challenges within children’s research health. For more information please visit: http://www.paediatrics.ox.ac.uk/ The Department of Paediatrics holds a silver Athena Swan award to recognise advancement of gender equality: representation, progression and success for all. Medical Sciences Division We are an internationally recognized centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: http://www.medsci.ox.ac.uk/ Department of Paediatrics, Sample Management Technician, Job Description 6 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert and recruitment@paediatrics.ox.ac.uk if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical https://staff.web.ox.ac.uk/recruitment-support-faqs troubleshooting advice is available at: Non-technical questions about this job should be addressed to the recruiting department directly at recruitment@paediatrics.ox.ac.uk or using the contact details in the online advertisement. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our e-recruitment system to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. 7 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/jobapplicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82 of 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 8 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as Universitysupported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. Oxford Research Staff Society (OxRSS) A society run by and for Oxford University research staff. It offers researchers a range of social and professional networking opportunities. Membership is free, and all researchers employed by Oxford University are welcome to join. Subscribe at researchstaff-subscribe@maillist.ox.ac.uk to join the mailing list to find out about upcoming events and other information for researchers, or contact the committee on committee@oxrss.ox.ac.uk. For more information, see www.ox.ac.uk/oxrss, Twitter/ X @ResStaffOxford, and Facebook www.facebook.com/oxrss. 9
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172048 Sample Management Technician Job Description.pdf
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Would you like a role as a sample management technician with the Oxford Vaccine Group? You could be part of a busy laboratory, that is a world leading site for Vaccine Clinical trials. Come and be a part of the group that developed one of the Covid-19 vaccines that has reached 2 billion doses and is administered worldwide. The Oxford Vaccine Group (OVG) are seeking enthusiastic, team-oriented people to join the group. This role will be essential in supporting clinical trials that are helping to understand infectious diseases, develop new vaccines and improve pre-existing vaccines for children and adults. Our research has led to the much-anticipated introduction of the Meningitis B vaccine for babies into the UK vaccination schedule, and we have been extensively involved in first in human trials of new vaccines to protect against SARS-CoV-2, the Ebola Virus and run internationally renowned Human Challenge Models of Enteric diseases such as Typhoid and Paratyphoid. The ideal candidate will work with the team in helping to manage the tens and thousands of samples that we have and ensuring they are in a well catalogued and efficient storage system. If you are keen to be part of a research environment, can work independently, manage your own time, are proactive, have good communication skills with great attention to detail then this role would be suited to you. The samples are in freezers across multiple locations, with incoming samples coming continually from national and international sites. Accurate inventories, helping consolidation of boxes, working to ensure efficient space management are all integral to allow research to continue seamlessly. Flexible working hours with a requirement to work later hours, travel to various locations where freezer storage is located or weekends may be required. You will be required to upload a CV and Supporting Statement as part of your online application. The Supporting Statement should include a cover letter and should also clearly describe how you meet each of the selection criteria listed in the job description. Click here for information and advice on writing an effective Supporting Statement. Only applications received before 12.00 midday on 17/04/2024 will be considered. Interviews will be held shortly after. To discuss the post in more detail please contact Dr Sagida Bibi and Suzanne Woodlock using the details below.
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Standard Grade 4: £25,138- £28,759 per annum (with a discretionary range to £31,396 per annum)