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"""Job description Post Research Fellow Department Biology Division Mathematical, Physical and Life Sciences Division (MPLS) Location Sir William Dunn School of Pathology, South Parks Rd, Oxford OX1 3RE Grade and salary Grade 8: £45,585-£54,395 per annum, with a discretionary range up to £59,421 Hours Full time Contract type Fixed-term to 30 November 2024 Reporting to Professor Samuel Sheppard Application deadline 12 noon on Wednesday 24th April 2024 Vacancy reference 172204 Recruitment contacts HR: recruitment@biology.ox.ac.uk Research topic Microbiology Principal Investigator / supervisor Professor Samuel Sheppard The role Reporting to Professor Samuel Sheppard. The post holder is a member of a research group providing day-to-day supervision for research assistants. The post holder is responsible for their own grant funded research project within a discrete area of a wider research programme. Responsibilities • Develop research questions within a specific context, conduct individual research, analysing detailed and complex qualitative and/or quantitative data from a variety of sources, and generate original ideas by building on existing concepts • Develop, establish, and pursue appropriate analytical protocols and techniques to support research • Support the PI in the day-to-day running of the lab liaising in person with group members. • Regularly write research articles at a national level for peer-reviewed journals, book chapters, and reviews. Present papers at national conferences, and lead seminars to disseminate research findings • Agree clear task objectives, organise, and delegate work to other members of the team and coach other members of the group on specialist methodologies or procedures • Raise research funds through grant applications, and manage own area of a larger research budget • Share responsibility for shaping the research group’s plans and the writing of group-funding applications for new research projects • Liaise with funding bodies and provide information to project stakeholders and represent the research group at external meetings/seminars, either with other members of the team or alone • Carry out collaborative projects with colleagues in partner institutions, and research groups • Teach or undertake ad-hoc paid teaching (this may include lecturing, demonstrating, small group teaching, tutoring of undergraduates and graduate students and supervision of projects). • Embed the principles of mutual respect, equality, diversity, inclusivity and sustainability in all aspects of your work; undertake training as and when asked to do so. Selection criteria Essential selection criteria • Hold a relevant Ph.D./D.Phil or is near to completion, with post-qualification research experience • Strong publication record and familiarity with the existing literature and research in the field. • Possess sufficient specialist knowledge in the discipline to develop research projects and methodologies • Ability to independently plan and manage a research project, including a research budget • Ability to raise research funds through making grant applications • Experience working on enteric bacteria in Africa • Experience using genomic epidemiology databases including PubMLST • Experience running genome sequencing projects (including wet lab skills) Desirable selection criteria • Experience of supervising staff • Experience of managing a research budget • Experience of making grant applications . Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • Working with infectious pathogens (hazard group 2/3) - Hazard Group 3 pathogens • Working with blood, human products and human tissues • Work with allergens, E.g. laboratory animals, pollen, dust, fish, insects etc. • Work with any substance which has any of the following pictograms on their MSDS: About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. The Department of Biology You will be joining the Department of Biology at an exciting time. The Department established from August 2022 as a result of a merger between the Departments of Zoology and Plant Sciences, and is preparing to move into the new state-of-the-art Life and Mind Building in two to three years time. The Department of Biology is recognised internationally for its research in a wide range of fields spanning all levels from molecules to ecosystems, and tackling global challenges through fundamental bioscience research. Over time, the research interests of the Department has been focused on five primary themes: Behaviour & Biomechanics; Ecology & Conservation; Evolutionary Biology; Microbiology & Infectious Disease; and Molecular Plant Biology. Research is conducted in all spheres from laboratory and in silico analysis to theoretical and field-based research. At all times we seek to reinforce the connections between research and our education offering, at both graduate and undergraduate level. The Department teaches a four-year undergraduate degree MBiol course in Biology, with fourth-year students undertaking a Masters-level research project. It also supports a variety of graduate placements and hosts the University’s DPhil in Biology. External research income to the Department is derived from over 50 different funding agencies, with the principal current funders being the European Research Council, the Royal Society, the Wellcome Trust, BBSRC and NERC. The Department has a significant record in integrating broader societal impacts of its research, including the provision of policy to government at the highest level, as well as supporting the commercialisation of research through spin-out companies and licensing arrangements that have generated hundreds of millions of pounds’ worth of innovation. The Department is located in the University’s Science Area at two sites, and will move into the new £200m Life and Mind Building in 2024 that will include extensive laboratory provision with controlled environment rooms, glasshouses and an imaging suite. The Department also benefits from extensive facilities at the John Krebs Field Station at Wytham, with Wytham Woods nearby, as well as partnerships with organisations in the area such as the Oxford Botanic Gardens and Oxford Natural History Museum. For more information please visit: https://www.biology.ox.ac.uk About the Mathematical, Physical, and Life Sciences (MPLS) Division The Mathematical, Physical, and Life Sciences (MPLS) Division is one of the four academic divisions of the University, alongside the Humanities, Social Sciences and Medical Sciences Divisions. It is led by an academic Head of Division (Professor Sam Howison) and an administrative Divisional Registrar (Dr Tracy Gale) and comprises nine of the University’s academic departments – Biology, Chemistry, Computer Science, Earth Sciences, Engineering Science, Materials, the Mathematical Institute, Physics, and Statistics – as well as Begbroke Science Park, the multidisciplinary Ineos Oxford Institute for Antimicrobial Research and an interdisciplinary Doctoral Training Centre. The disciplines within the MPLS Division regularly appear at the highest levels in rankings, including the Times Higher Education and QS world rankings. Nationally, the quality of the Division’s research outputs and environment, and the resulting impact, was recognised through strong performances in the UK Research Excellence Framework in both 2014 and 2021. MPLS is proud to be home to some of the most creative and innovative scientific thinkers and leaders in academia, whose interdisciplinary research is tackling major societal and technological challenges, from new energy solutions or improved cancer treatments to understanding climate change processes and helping to preserve biodiversity, tackling antimicrobial resistance, advancing AI and quantum technologies and space exploration, and much more. The quality and impact of our work have been recognised by successive rounds of the national Research Excellence Framework and Teaching Excellence and Student Outcomes Framework exercises, and our departments frequently top the major higher education league tables. We teach around 7,300 students (including around 3,400 graduate students) and are playing a key part in training the next generation of leading scientists. Divisional activity is co-ordinated and represented by the MPLS Divisional Office based at 9 Parks Road, in the heart of Oxford’s Science Area. The Divisional Office, which is led by the Divisional Registrar, has around 55 dedicated members of staff, as well as a number of colleagues who are embedded in divisional teams but based in central University services (e.g. in Finance, HR and Development). To find out more, please visit: www.mpls.ox.ac.uk. How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs Non-technical questions about this job should be addressed to the recruiting department directly at recruitment@Biology.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependants. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. """^^ . . . . "Department of Biology" . . . "Past vacancies at the University of Oxford" . "sotto-Organization di"@it . . . "application/xhtml+xml" . "page" . "Biochemistry and Biological Sciences Teaching Centre" . "homepage" . "2024-04-24T12:00:00+01:00"^^ . "Mathematical, Physical and Life Sciences (MPLS)" . "2024-04-10T09:00:00+01:00"^^ . "name" . . . "text/plain" . "value" . "way/52173939 way/303646539" . "Sir William Dunn School of Pathology" . "Estates identifier" . . "application/pdf" . "OxPoints"@en . . "valid through (0..1)"@en . . _:N7a3ed3304bea46f5bf0a27b9c6bc9056 . . . 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House crowding, cohabitation with animals and poor sanitation/food safety are all potential risk factors, but effective interventions depend upon quantitative estimates of infection sources. The epidemiology of campylobacteriosis is poorly understood in LMICs. In pilot studies, we have identified genomic variation in strains that may indicate differences in source, survival, transmission and virulence (compared to the UK). In particular, we have identified globally and locally distributed strains, evidence of within household spread and strains associated with asymptomatic infection and infection with other enteropathogens. Genome sequencing technologies and bioinformatics analysis provide a means for explaining these cryptic disease networks by identifying differences between strains from multiple sources, and tracking their transmission. Building on an established collaborative network in the UK and Africa (The Gambia, Ghana, Burkina Faso), the post holder will support a program of globalized _Campylobacter_ NGS surveillance. Specifically, (i) sampling and genome sequence isolates from animals, food, environmental sources and people (symptomatic, asymptomatic, and matched cases and controls); (ii) developing open-access databases and novel analysis pipelines (association study and machine learning) to characterize _Campylobacter_ population structure and identify source attribution markers; (iii) quantifying the relative contribution of different human infection sources. This evidence-based approach will enable effective local public health and policy interventions and focus efforts to reducing the burden of diarrhoeal disease in Africa. **About you** We seek an enthusiastic new colleague who holds a relevant PhD/DPhil, together with relevant experience. It is essential that you have previous experience **How to apply** Applications for this vacancy are to be made online via our e-recruitment system, and should include the application letter, a CV, a list addressing the job criteria, and names of two academic references. Where Covid-19 has resulted in substantial disruption to your work or research outputs, please explain this by providing an additional paragraph in your supporting statement. The University of Oxford is committed to equality and valuing diversity. All applicants will be judged on merit, according to the selection criteria. This post is a 6-month fixed term, full time position and is available from 01 May 2024. The closing date for applications is 12.00 noon on Wednesday 24th April 2024 For further inquiries, please contact Samuel Sheppard samuel.sheppard@biology.ox.ac.uk """ . "Tubney Panthera Buildings" . . . . "Subject"@en . . . "OxPoints"@en . . "preferred label"@en . "Agent" . . "longitude" . . . . 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About the role

Diarrhoeal disease remains a major cause of child morbidity, growth faltering and mortality in low and middle income countries (LMICs), with Campylobacter among the most common causes. The major infection sources in the UK include contaminated food, but transmission routes in LMICs are unknown. This means that transmission among the children at highest risk (85% infected before 1yr in LMICs) is the least studied. House crowding, cohabitation with animals and poor sanitation/food safety are all potential risk factors, but effective interventions depend upon quantitative estimates of infection sources.

 

The epidemiology of campylobacteriosis is poorly understood in LMICs. In pilot studies, we have identified genomic variation in strains that may indicate differences in source, survival, transmission and virulence (compared to the UK). In particular, we have identified globally and locally distributed strains, evidence of within household spread and strains associated with asymptomatic infection and infection with other enteropathogens. Genome sequencing technologies and bioinformatics analysis provide a means for explaining these cryptic disease networks by identifying differences between strains from multiple sources, and tracking their transmission.

 

Building on an established collaborative network in the UK and Africa (The Gambia, Ghana, Burkina Faso), the post holder will support a program of globalized Campylobacter NGS surveillance. Specifically, (i) sampling and genome sequence isolates from animals, food, environmental sources and people (symptomatic, asymptomatic, and matched cases and controls); (ii) developing open-access databases and novel analysis pipelines (association study and machine learning) to characterize Campylobacter population structure and identify source attribution markers; (iii) quantifying the relative contribution of different human infection sources. This evidence-based approach will enable effective local public health and policy interventions and focus efforts to reducing the burden of diarrhoeal disease in Africa. 

 

About you

We seek an enthusiastic new colleague who holds a relevant PhD/DPhil, together with relevant experience. It is essential that you have previous experience

 

How to apply

Applications for this vacancy are to be made online via our e-recruitment system, and should include the application letter, a CV, a list addressing the job criteria, and names of two academic references. Where Covid-19 has resulted in substantial disruption to your work or research outputs, please explain this by providing an additional paragraph in your supporting statement.

 

The University of Oxford is committed to equality and valuing diversity. All applicants will be judged on merit, according to the selection criteria.

 

This post is a 6-month fixed term, full time position and is available from 01 May 2024. 

 

The closing date for applications is 12.00 noon on Wednesday 24th April 2024

 

For further inquiries, please contact Samuel Sheppard samuel.sheppard@biology.ox.ac.uk
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