Postdoctoral Researcher

********** Please note this is a re-advertisement and previous applicants need
not apply** **** ****





**About the role**





Working with Prof. Peter McHugh's research group to contribute to the study of
DNA repair.





The post holder will be responsible for characterising repair factors through
structural biology techniques, with a focus on cryo-electron microscopy. Ideal
candidates should have expertise in molecular cloning, protein expression,
purification, and structural methods, preferably in crystallography and
electron microscopy. Knowledge of DNA modification enzymes and a background in
DNA damage and repair fields are highly desirable.





Your responsibilities encompass testing hypotheses, managing academic
research, developing scientific techniques, characterizing nucleases, staying
updated on DNA repair advancements, and contributing to projects and grant
proposals. You'll attend meetings, present reports, engage in scientific
presentations, write for publication, and ensure compliance with safety
protocols. Additionally, you'll manage lab equipment, provide guidance to team
members, train juniors, and participate in public engagement activities.





The post will be based at the Weatherall Institute of Molecular Medicine, John
Radcliffe Hospital, Headington, Oxford OX3 9DU , and is offered on a full-time
basis, fixed-term for 2 years in first instance.





**About you**





You will be required to have research experience in molecular cloning, cell
culturing, cryo-electron microscopy, X-ray crystallography, and
protein/complex characterization. A strong record of publishing in reputable
journals and contributing to grant proposals is essential. Your role will
involve managing research projects, mentoring junior researchers,
collaborating internally and externally, and organizing and prioritizing work
independently. Excellent written and oral communication skills, including
presenting at international symposia and to non-specialist audiences, are also
crucial.





Applicants should hold a PhD (or be near to completion) in structural biology
molecular biology or biochemistry.





**Application Process**





You will be required to upload a supporting statement (setting out how you
meet the selection criteria), a curriculum vitae and the names and contact
details of two referees as part of your online application.





Only applications received before **noon on Monday, 28th May 2024** can be
considered.





**Committed to equality and valuing diversity**