Working with Prof. Peter McHugh's research group to contribute to the study of DNA repair.

 

The post holder will be responsible for characterising repair factors through structural biology techniques, with a focus on cryo-electron microscopy. Ideal candidates should have expertise in molecular cloning, protein expression, purification, and structural methods, preferably in crystallography and electron microscopy. Knowledge of DNA modification enzymes and a background in DNA damage and repair fields are highly desirable.

 

Your responsibilities encompass testing hypotheses, managing academic research, developing scientific techniques, characterizing nucleases, staying updated on DNA repair advancements, and contributing to projects and grant proposals. You'll attend meetings, present reports, engage in scientific presentations, write for publication, and ensure compliance with safety protocols. Additionally, you'll manage lab equipment, provide guidance to team members, train juniors, and participate in public engagement activities.

 

The post will be based at the Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DU , and is offered on a full-time basis, fixed-term for 2 years in first instance.

 

 

You will be required to have research experience in molecular cloning, cell culturing, cryo-electron microscopy, X-ray crystallography, and protein/complex characterization. A strong record of publishing in reputable journals and contributing to grant proposals is essential. Your role will involve managing research projects, mentoring junior researchers, collaborating internally and externally, and organizing and prioritizing work independently. Excellent written and oral communication skills, including presenting at international symposia and to non-specialist audiences, are also crucial.

 

Applicants should hold a PhD (or be near to completion) in structural biology molecular biology or biochemistry.

 

 

You will be required to upload a supporting statement (setting out how you meet the selection criteria), a curriculum vitae and the names and contact details of two referees as part of your online application.

 

Only applications received before noon on Monday, 28th May 2024 can be considered.