"Department of Biology" . . "Mathematical, Physical and Life Sciences (MPLS)" . "John Krebs Field Station, Wytham" . . "51.757526"^^ . . . "Biology South Parks Road" . . . . "email"@en . "way/671231558" . "sotto-Organization di"@it . "longitude" . . . "Unit price specification"@en . "51811513"^^ . . _:Nbdccc9722e5c46d88ddb015437785d13 . "Tubney Panthera Buildings" . _:Nbdccc9722e5c46d88ddb015437785d13 . "Biology" . . "Department of Biology" . "Department of Biology, 11a Mansfield Road, Oxford OX1 3SZ" . "department" . . . . "Past vacancies at the University of Oxford" . . "postal code"@en . _:N3d39490152074da3948c26681a1231c4 "United Kingdom" . . . . _:N3d39490152074da3948c26681a1231c4 . "address"@en . "label" . "Biology Mansfield Road" . . . . "Tubney House" . . "notation"@en . . "Subject"@en . "extended address"@en . "Agent" . . "true"^^ . . "Format"@en . . . . . "based near" . . . . . . . . . . . . "Standard Grade 7: £36,024 - £44,263" . "HR" . . 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"Postdoctoral Research Associate in Protein Structure and Cell Evolution" . _:N3d39490152074da3948c26681a1231c4 "Oxford" . . "tiene sede en"@es . . "has site"@en . "John Krebs Field Station, Wytham" . "-1.25124"^^ . "Title"@en . . . """You will join the Richards molecular microbiology group with responsibility for carrying out research for a Leverhulme Trust project with aim of characterising the structural biology of unique fungal organelles associated with rhodopsin function and phototaxis (a putative subcellular eye). The project will focus on using cutting edge structural microscopy (FIB-SEM and CryoET) to characterise prominent uniform structures found in these organelles (working between the departments of Biology and Biochemistry). You must be capable of working independently and will be responsible for developing new protocols for isolation of sub cellular fractions and performing CryoET, FIB-SEM, subtomogram analysis and model building. The successful candidate must also take these data through to protein structural bioinformatic analyses. You will have the opportunity to collaborate in the preparation of research publications and presenting papers at conferences or public meetings. The successful applicant must hold or be close to completion of a relevant PhD/DPhil, together with experience in protein structural biology and feel confident working between two diverse research groups. You will possess sufficient specialist knowledge in the discipline of cryogenic electron microscopy to work within established research programmes. You will have the ability to manage your own academic and associated activities. Excellent communications skills, including the ability to write for publications, present research proposals and results, and represent the research group at meetings is essential. Where Covid-19 has resulted in substantial disruption to your work or research outputs, please explain this by providing an additional paragraph in your supporting statement. The University of Oxford is committed to equality and valuing diversity. All applicants will be judged on merit, according to the selection criteria. This post is full time and available immediately. The closing date for applications is 12.00 noon on Friday 23 August 2024, interviews are likely to be scheduled for late August. Applications for this vacancy are to be made online via our e-recruitment system, and you will be required to upload a supporting statement and CV as part of your online application. """ . . "OxPoints"@en . . "text/html" . "NTriples description of Postdoctoral Research Associate in Protein Structure and Cell Evolution" . "Tubney House" . "Biochemistry and Biological Sciences Teaching Centre" . """Job description Post Postdoctoral Research Associate in Protein Structure and Cell Evolution Department Department of Biology Division Mathematical, Physical and Life Sciences Division (MPLS) Location 11a Mansfield Road Grade and salary Grade 7: £36,024 - £44,263 p.a. Hours Full time Contract type Fixed term (24 months with the potential to extend to 36 months subject to funding) Reporting to Thomas Richards Application deadline 12 noon on Friday 23 August 2024 Vacancy reference 173937 Recruitment contacts Additional information HR: recruitment@biology.ox.ac.uk or PI: Thomas.richards@biology.ox.ac.uk Whilst the role is a grade 7 position, we would be willing to consider candidates with potential but less experience who are seeking a development opportunity, for which an initial appointment would be at grade 6 (£32,332 - £38,205 per annum) with the responsibilities adjusted accordingly. This would be discussed with applicants at interview/appointment where appropriate. This role will be a collaborative postdoctoral research project between Prof Matt Higgins in the Department of Biochemistry and Prof Thomas Richards in the Department of Biology. Research topic Structural Biology of a Fungal Eye Principal Investigator / supervisor Prof Thomas Richards Funding partner Leverhulme Trust / Gordon and Betty Moore Foundation Recent publications Galindo et al. 2022: https://doi.org/10.1016/j.cub.2022.05.034 Broser et al. 2023: https://doi.org/10.1073/pnas.2310600120 Avelar et al. 2014: DOI:https://doi.org/10.1016/j.cub.2014.04.009 The role Reporting to Tom Richards & Matt Higgins. The post holder is a member of the Richards molecular microbiology group with responsibility for carrying out research for a Leverhulme Trust project with aim of characterising the structural biology of unique fungal organelles associated with rhodopsin function and phototaxis (a putative subcellular eye). The project will focus on using cutting edge structural microscopy (FIB-SEM and CryoET) to characterise prominent uniform structures found in these organelles. The post holder must be capable of working independently and will be responsible for developing new protocols for isolation of sub cellular fractions and performing CryoET, FIB-SEM, subtomogram analysis and model building. The successful candidate must also take these data through to protein structural bioinformatic analyses. The research team provides the environment to support this primary work (and full training can be provided on cryogenic electron microscopy methods at the COSMIC facility) but also expand the analysis into wider evolutionary analysis including organellar proteome phylogenomic analyses. There will be opportunities for the post holder to provide guidance to less experienced members of the research group, including postdocs, research assistants, technicians, and PhD and project students. Responsibilities • • • • • • • • • • • • Manage own academic research and administrative activities. This involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines. Adapt existing and develop new research methodologies and materials focusing on microbe cultivation, cell fractionation, Cryo-fixation, CryoET and FIB-SEM microscopy and related bioinformatic analyses. Prepare working theories and analyse qualitative and/or quantitative data from a variety of sources, reviewing and refining theories as appropriate. Collaborate in the preparation of research publications. Contribute ideas for new research projects. Develop ideas for generating research income and present detailed research proposals to senior researchers. Present papers at conferences or public meetings Act as a source of information and advice to other members of the group on methodologies or procedures. Represent the research group at external meetings/seminars, either with other members of the group or alone Carry out collaborative projects with colleagues in partner institutions, and research groups. Teach or undertake ad-hoc paid teaching (this may include lecturing, demonstrating, small group teaching, tutoring of undergraduates and graduate students and supervision of projects). Embed the principles of mutual respect, equality, diversity, inclusivity and sustainability in all aspects of your work; undertake training as and when to do so. Selection criteria Essential selection criteria • • • • • Hold or be close to completion of a relevant PhD/DPhil, together with experience in protein structural biology. Possess sufficient specialist knowledge in the discipline of cryogenic electron microscopy to work within established research programmes. Ability to manage own academic research and associated activities. Previous experience of contributing to publications/presentations Excellent communication skills, including the ability to write for publication, present research proposals and results, and represent the research group at meetings. Desirable selection criteria • • Experience of independently managing a discrete area of a research project Experience of actively collaborating in the development of research articles for publication Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • Lone Working • Work in hot or cold environments. • Driving on University business • Working with Ionising Radiation • Working with category 3b or 4 lasers (laser safety class) • Work with allergens, Eg laboratory animals, pollen, dust, fish or insects etc. • Work with any substance which has any of the following pictograms on their MSDS: • Travel outside of Europe or North America on University Business About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. The Department of Biology You will be joining the Department of Biology at an exciting time. The Department established from August 2022 as a result of a merger between the Departments of Zoology and Plant Sciences, and is preparing to move into the new state-of-the-art Life and Mind Building in two to three years time. The Department of Biology is recognised internationally for its research in a wide range of fields spanning all levels from molecules to ecosystems, and tackling global challenges through fundamental bioscience research. Over time, the research interests of the Department has been focused on five primary themes: Behaviour & Biomechanics; Ecology & Conservation; Evolutionary Biology; Microbiology & Infectious Disease; and Molecular Plant Biology. Research is conducted in all spheres from laboratory and in silico analysis to theoretical and field-based research. At all times we seek to reinforce the connections between research and our education offering, at both graduate and undergraduate level. The Department teaches a four-year undergraduate degree MBiol course in Biology, with fourth-year students undertaking a Masters-level research project. It also supports a variety of graduate placements and hosts the University’s DPhil in Biology. External research income to the Department is derived from over 50 different funding agencies, with the principal current funders being the European Research Council, the Royal Society, the Wellcome Trust, BBSRC and NERC. The Department has a significant record in integrating broader societal impacts of its research, including the provision of policy to government at the highest level, as well as supporting the commercialisation of research through spin-out companies and licensing arrangements that have generated hundreds of millions of pounds’ worth of innovation. The Department is located in the University’s Science Area at two sites, and will move into the new £200m Life and Mind Building in 2024 that will include extensive laboratory provision with controlled environment rooms, glasshouses and an imaging suite. The Department also benefits from extensive facilities at the John Krebs Field Station at Wytham, with Wytham Woods nearby, as well as partnerships with organisations in the area such as the Oxford Botanic Gardens and Oxford Natural History Museum. For more information please visit: https://www.biology.ox.ac.uk About the Mathematical, Physical, and Life Sciences (MPLS) Division The Mathematical, Physical, and Life Sciences (MPLS) Division is one of the four academic divisions of the University, alongside the Humanities, Social Sciences and Medical Sciences Divisions. It is led by an academic Head of Division (Professor Sam Howison) and an administrative Divisional Registrar (Dr Tracy Gale) and comprises nine of the University’s academic departments – Biology, Chemistry, Computer Science, Earth Sciences, Engineering Science, Materials, the Mathematical Institute, Physics, and Statistics – as well as Begbroke Science Park, the multidisciplinary Ineos Oxford Institute for Antimicrobial Research and an interdisciplinary Doctoral Training Centre. MPLS is proud to be home to some of the most creative and innovative scientific thinkers and leaders in academia, whose interdisciplinary research is tackling major societal and technological challenges, from new energy solutions or improved cancer treatments to understanding climate change processes and helping to preserve biodiversity, tackling antimicrobial resistance, advancing AI and quantum technologies and space exploration, and much more. The quality and impact of our work have been recognised by successive rounds of the national Research Excellence Framework and Teaching Excellence and Student Outcomes Framework exercises, and our departments frequently top the major higher education league tables. We teach around 7,300 students (including around 3,400 graduate students) and are playing a key part in training the next generation of leading scientists. Divisional activity is co-ordinated and represented by the MPLS Divisional Office based at 9 Parks Road, in the heart of Oxford’s Science Area. The Divisional Office, which is led by the Divisional Registrar, has around 55 dedicated members of staff, as well as a number of colleagues who are embedded in divisional teams but based in central University services (e.g. in Finance, HR and Development). To find out more, please visit: www.mpls.ox.ac.uk. How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs Non-technical questions about this job should be addressed to the recruiting department directly at Recruitment@Biology.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependants. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. """^^ . . "Biology Mansfield Road" . "OxPoints"@en . . "occupies" . . . . "name" . . . . . . . _:N3d39490152074da3948c26681a1231c4 "OX1 3SZ" . . "2024-08-23T12:00:00+01:00"^^ . . "RDF/XML description of Postdoctoral Research Associate in Protein Structure and Cell Evolution" . . . "street address"@en . . "2024-08-23T12:00:00+01:00"^^ . _:N3d39490152074da3948c26681a1231c4 "Zoology Research and Administration Building" . "Biochemistry and Biological Sciences Teaching Centre" . . "ha sede"@it . . _:N3d39490152074da3948c26681a1231c4 "11a Mansfield Road" . . "text/n3" . . "homepage" . . . . "page" . . "type" . . . 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You will join the Richards molecular microbiology group with responsibility for carrying out research for a Leverhulme Trust project with aim of characterising the structural biology of unique fungal organelles associated with rhodopsin function and phototaxis (a putative subcellular eye).

 

The project will focus on using cutting edge structural microscopy (FIB-SEM and CryoET) to characterise prominent uniform structures found in these organelles (working between the departments of Biology and Biochemistry). You must be capable of working independently and will be responsible for developing new protocols for isolation of sub cellular fractions and performing CryoET, FIB-SEM, subtomogram analysis and model building. The successful candidate must also take these data through to protein structural bioinformatic analyses. You will have the opportunity to collaborate in the preparation of research publications and presenting papers at conferences or public meetings.

 

The successful applicant must hold or be close to completion of a relevant PhD/DPhil, together with experience in protein structural biology and feel confident working between two diverse research groups. You will possess sufficient specialist knowledge in the discipline of cryogenic electron microscopy to work within established research programmes. You will have the ability to manage your own academic and associated activities. Excellent communications skills, including the ability to write for publications, present research proposals and results, and represent the research group at meetings is essential.

 

Where Covid-19 has resulted in substantial disruption to your work or research outputs, please explain this by providing an additional paragraph in your supporting statement.

 

The University of Oxford is committed to equality and valuing diversity. All applicants will be judged on merit, according to the selection criteria.

 

This post is full time and available immediately.

 

The closing date for applications is 12.00 noon on Friday 23 August 2024, interviews are likely to be scheduled for late August. Applications for this vacancy are to be made online via our e-recruitment system, and you will be required to upload a supporting statement and CV as part of your online application.
"""^^ .