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"RDF/XML description of Postdoctoral Research Scientist in STRUBI" . "sotto-Organization di"@it . . . . . . . "2024-08-16T12:00:00+01:00"^^ . "License"@en . . "University of Oxford" . . "value" . . . _:N3aa3e9f3128b4077aa2dd372426d3b20 "Oxford" . . "has primary place" . . . "Oxford Particle Imaging Centre" . . . "NTriples description of Postdoctoral Research Scientist in STRUBI" . "174208"^^ . """We have an exciting opportunity for a Postdoctoral Research Scientist to join our fantastic group of scientists here at the Division of Structural Biology, Nuffield Department of Medicine. You will be working in Professor Jones’ and Professor Tzima’s groups at the Division of Structural Biology, working closely to investigate the role of cell guidance receptors in mechanotransduction. These groups work in the area of mechanotransduction, fluidics, and biophysical studies to characterise novel molecular assemblies. The laboratories are at the cutting edge of developments in production of samples for structural biology using mammalian cell-based expression systems as well as cell-based and in vivo models of mechanotransduction. As Postdoctoral Research Scientist, you will be responsible for managing your own academic research activities. This involves small scale project management to co-ordinate multiple aspects of work and meet deadlines. You will be tasked with testing hypotheses and analysing scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. You will be acting as a source of information and advice to other members of the group on scientific protocols and experimental techniques. It is essential that you hold a PhD/DPhil (or close to completion) in a relevant subject along with experience in mammalian (preferably endothelial) cell culture; shear stress application models; tensional force assays; confocal imaging; western blotting. You will have research experience in cell- based assays and in production of samples for structure/function studies. You will also be able to manage the day-to-day running of a research project including assisting the work of junior researchers. Finally, you will have Good communication skills, including the ability to present work at international symposia and to non-specialist audiences. Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a fixed term contract until 31 August 2025 and is funded by the European Commission. Only applications received before 12 midday on Friday 16 August 2024 will be considered. Please quote **174208** on all correspondence. """ . . "latitude" . . . . "has site"@en . . _:N3aa3e9f3128b4077aa2dd372426d3b20 "Wellington Square" . "homepage" . . """Job title Postdoctoral Research Scientist in STRUBI Division Medical Sciences Department Nuffield Department of Medicine Location Division of Structural Biology, Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN Grade and salary Grade 7: £36,024 - £44,263 with a discretionary range to £48,350 per annum Hours Full time Contract type Fixed-term contract for 31 August 2025 Funding is provided by the European Commission Reporting to Professor Yvonne Jones, Principal Investigator Vacancy reference 174208 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship under UK Visas and Immigration legislation. Therefore, the Nuffield Department of Medicine welcomes applications from international applicants who require a visa. About us    What we offer https://hr.admin.ox.ac.uk/staff-benefits  An excellent contributory pension scheme  38 days annual leave  A comprehensive range of childcare services  Family leave schemes  Cycle loan scheme  Discounted bus travel and Season Ticket travel loans  Membership to a variety of social and sports clubs  A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - www.ndm.ox.ac.uk Unit - www.strubi.ox.ac.uk The role Professor Jones’ and Professor Tzima’s groups at the Division of Structural Biology work closely to investigate the role of cell guidance receptors in mechanotransduction. The laboratories are at the cutting edge of developments in production of samples for structural biology using mammalian cellbased expression systems as well as cell-based and in vivo models of mechanotransduction. Research projects are typically highly interdisciplinary, aiming to integrate in vitro biophysical measurements, high resolution x-ray crystallographic analyses, electron cryo microscopy (cryoEM), and cell-based fluidics studies. Recent publications from the groups include Powell et al Science 2024, Nagy et al Nature Commun. 2024, Mehta et al Science Advances, McGough et al Nature 2020, Mehta et al Nature 2020, Kong et al Neuron 2016, Kakugawa et al Nature 2015. We currently have the opportunity for a highly-motivated Postdoctoral Research Scientist to join the groups to work in the area of mechanotransduction, fluidics, and biophysical studies to characterise novel molecular assemblies. You will join a very motivated international and interdisciplinary group of scientists. Responsibilities You will:             Manage your own academic research activities. This involves small scale project management to co-ordinate multiple aspects of work and meet deadlines. Adapt existing and develop new scientific techniques and experimental protocols. Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. Contribute ideas for new research projects. Contribute to the presentation of scientific results through journal articles, posters and oral presentations at national/international conferences. Use specialist scientific equipment in a laboratory environment. Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques. Represent the research group at external meetings/seminars, either with other members of the group or alone. Carry out collaborative projects with colleagues in partner institutions, and within the Jones research group. Comply with due regard to the University’s Equal Opportunities and Data Protection policies. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. 1 Selection criteria Essential          Hold a PhD/DPhil (or close to completion) in a relevant subject; Experience in mammalian (preferably endothelial) cell culture; shear stress application models; tensional force assays; confocal imaging; western blotting; Research experience in production of samples for structure/function studies; Research experience in cell-based assays; Documented evidence of work at the level expected of first author publication in a leading refereed journal; Ability to work independently; Ability to manage the day-to-day running of a research project including assisting the work of junior researchers; Good communication skills, including the ability to present work at international symposia and to non-specialist audiences; Ability to work as part of a team. Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows:     Lone Working Work in hot or cold environments Working with infectious pathogens (hazard group 2/3) - Hazard Group 3 pathogens Work with any substance which has any of the following pictograms on their MSDS: 2 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents.  http://www.ox.ac.uk/about_the_university/jobs/research/ All applications must be received by midday UK time on the closing date stated in the online advertisement Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement 3 The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 4 """^^ . 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We have an exciting opportunity for a Postdoctoral Research Scientist to join our fantastic group of scientists here at the Division of Structural Biology, Nuffield Department of Medicine. You will be working in Professor Jones’ and Professor Tzima’s groups at the Division of Structural Biology, working closely to investigate the role of cell guidance receptors in mechanotransduction. These groups work in the area of mechanotransduction, fluidics, and biophysical studies to characterise novel molecular assemblies. The laboratories are at the cutting edge of developments in production of samples for structural biology using mammalian cell-based expression systems as well as cell-based and in vivo models of mechanotransduction.

 

As Postdoctoral Research Scientist, you will be responsible for managing your own academic research activities. This involves small scale project management to co-ordinate multiple aspects of work and meet deadlines. You will be tasked with testing hypotheses and analysing scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. You will be acting as a source of information and advice to other members of the group on scientific protocols and experimental techniques.

 

It is essential that you hold a PhD/DPhil (or close to completion) in a relevant subject along with experience in mammalian (preferably endothelial) cell culture; shear stress application models; tensional force assays; confocal imaging; western blotting. You will have research experience in cell-based assays and in production of samples for structure/function studies. You will also be able to manage the day-to-day running of a research project including assisting the work of junior researchers. Finally, you will have Good communication skills, including the ability to present work at international symposia and to non-specialist audiences.

 

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

 

This position is offered full time on a fixed term contract until 31 August 2025 and is funded by the European Commission.

 

Only applications received before 12 midday on Friday 16 August 2024 will be considered. Please quote 174208 on all correspondence.
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