Oxford Population Health (Nuffield Department of Population Health) contains world-renowned population health research groups and provides an excellent environment for multi-disciplinary research and teaching. The Clinical Trial Service Unit (CTSU) is a major international research institute within NDPH, and is one of the world’s leading centres for research into chronic diseases, especially heart disease, kidney disease and cancer. We are seeking a Clinical Research Fellow to work in a Cancer Research UK funded research programme that aims to quantify the benefits and risks of cancer treatments. This post would suit either a medical or clinical oncologist. The main role will be to quantify the risks from one or more systematic therapies using large-scale data in randomised trials. The post-holder will use their oncology expertise to identify relevant trials and extract data. These data will be analysed in partnership with statisticians within the team to produce dose-response relationships. The risks from systematic therapy can then be compared with the benefits, to inform clinical decisions for patients today. The post-holder may also provide oncology input to some of the other ongoing studies and meta-analyses being conducted within the group. This post must be held in conjunction with an honorary (non-stipendiary) contract with a relevant NHS Trust. To be considered for this role you will be medically qualified, GMC registered with a valid licence to practice and a Member or Fellow, of a relevant Royal College (or equivalent). You will also have a good grounding in oncology: for clinical oncologists, FRCR part 1 or equivalent; for medical oncologists, a national medical oncology training number or equivalent. You will have strong organisational and communication skills and an ability to work with attention to detail. The post is full time (although part time will be considered) and fixed term for 2 years in the first instance. Subject to passing selection criteria, there may be an opportunity for candidates to study for a DPhil. The closing date for applications is noon on Friday, 27 September 2024. You will be required to upload a CV and a cover letter as part of your online application. The cover letter should clearly describe how you meet each of the selection criteria listed in the job description.
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Job description Job title Oncology Research Fellow Division Medical Sciences Division Department Oxford Population Health (Nuffield Department of Population Health, University of Oxford) Location Old Road Campus, Headington, Oxford, OX3 7LF Grade and salary Grade E63 or E64 £64: £32,398 - £63,152 per annum dependent on qualifications and experience, in line with current pay protection and transitional arrangements in the NHS Hours Full time (part time considered) Contract type Fixed term – 2 years (in the first instance) Reporting to Professor Carolyn Taylor Vacancy reference 174658 Oncology Research Fellow - job description, August 2024 1 The Benefits and Risks of Cancer Treatments Team Our team, which is funded by Cancer Research UK and the University of Oxford, studies the effects of cancer treatments and forms part of Oxford Population Health. For cancer patients, individual treatment decisions can only be made on an informed basis if patients and clinicians have information on the absolute magnitudes of both the likely benefits and the risks of all the available management options. These can then be compared and the option with the best chance of a favourable outcome identified. Our overall research aim is to provide reliable information to do this. Our specific objectives arise from problems facing clinicians around the world on a daily basis in early invasive breast cancer, in-situ breast cancer, lymphoma and advanced cancers. Often, many treatment options are available, and selecting the best one is difficult. The Benefits and Risks Team comprises approximately fifteen people and includes oncologists, a surgeon, a medical physicist, statisticians, programmers, administrative staff and doctoral students. The team is led by Carolyn Taylor. Co-leaders are Sarah Darby (statistician), Paul McGale (statistician), David Cutter (clinical oncologist), David Dodwell (clinical oncologist) and Gurdeep Mannu (surgeon). The team also includes other statisticians, clinical fellows, DPhil students and a radiotherapy physicist (George Ntentas). About Oxford Population Health Oxford Population Health (the Nuffield Department of Population Health) provides an excellent environment for multi-disciplinary research and teaching and for professional and support staff. We work together to answer some of the most important questions about the causes, prevention and treatment of disease. The Department has around 900 staff, students and academic visitors working in a number of world-renowned population health research groups, including the Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), the Cancer Epidemiology Unit (CEU), the National Perinatal Epidemiology Unit (NPEU) and other groups working on public health, health economics, ethics and health record linkage. It is also a key partner in the Oxford University’s Big Data Institute. In the 2021 Research Excellence Framework (REF), 96% of the research submitted to Unit of Assessment 2: Public Health, Health Services and Primary Care, was ranked either 4* (world-leading in terms of originality, significance and rigour) or 3* (internationally excellent in terms of originality, significance and rigour). This comprised research from Oxford Population Health and research from the Nuffield Department of Primary Care Health Sciences. We scored particularly well for having an environment that is conducive to producing research of world-leading quality and enabling outstanding impact, in terms of its vitality and sustainability. In addition to its research activities, the Department is home to the MSc in Global Health Science and Epidemiology, the MSc in Clinical Trials, and a variety of short courses. Students also come to undertake research for DPhil degrees. Teaching is provided for undergraduates reading for Medicine and for public health doctors in specialist training. For more information please visit the Oxford Population Health website. About the Medical Sciences Division The Medical Sciences Division is an internationally recognised centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. Oncology Research Fellow - job description, August 2024 2 World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit the Medical Sciences Division website. About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information please visit the Oxford University website. The role The successful candidate will work in the ‘Benefits and Risks of Cancer Treatments’ team on the late effects of cancer treatments in studies that aim to impact clinical practice. This post would suit either a medical or clinical oncologist. The main role will be to quantify the risks from different systematic therapies using largescale data and novel methods. The team recently used these methods to produce preliminary analyses of heart disease after anthracycline chemotherapy. Anthracycline chemotherapy is commonly used in the curative treatment of several cancer types. Its main life-threatening effect is heart disease. The team have developed dose-response relationships based on much larger scale data than has previously been possible. These analyses may be used to estimate the cardiac risks of anthracycline chemotherapy for individual patients in the clinic today. The postholder will use similar methods to assess other risks, such as the risk of leukaemia after anthracycline chemotherapy. They will use their oncology expertise to identify relevant trials, extract data on chemotherapy doses, monitoring during chemotherapy and on numbers of events. The data will be analysed in partnership with statisticians within the team to produce dose-response relationships. The risks from systematic therapy can then be compared with the benefits, to inform clinical decisions for patients today. Oncology Research Fellow - job description, August 2024 3 If the postholder is a clinical oncologist, there may also be opportunities to contribute to studies of radiotherapy risks, using radiation dosimetry methods that have been developed by the team. These projects are led by the team in Oxford, and involve collaboration with oncologists, haematologists, statisticians, epidemiologists, and other scientists throughout the world. The successful applicant will be part of a strong and established team who aim to carry out research of the highest methodological quality and with the greatest possible influence on cancer treatments. The post-holder will work as an independent scientist within our established research team. They will take responsibility for the implementation and extension of existing and planned studies (some are described above). There would be the possibility for the innovation and design of new related studies. Oncological expertise will be combined with statistical and epidemiological skills within our team to produce results that are relevant to clinical practice. The post-holder may also provide additional oncology input to some of the other ongoing studies and meta-analyses being conducted within the group. Subject to passing selection criteria, there may be an opportunity for candidates to study for a DPhil. For an informal discussion: Please contact: Professor Carolyn Taylor carolyn.taylor@ndph.ox.ac.uk Responsibilities Specific areas of responsibility include:  Developing new areas of research into the late effects of cancer treatments  Developing an understanding of the rationale behind the work and becoming familiar with the relevant literature  Identifying relevant trials and then extracting, summarising and organising data from the trial publications  Preparing scientific articles for publication, sometimes as main author and sometimes as contributing author  Presenting at Regional, National and International meetings and at internal seminars and scientific meetings  Contribution of general oncology expertise to the team’s studies  To contribute, as required to the wider academic activities of Oxford Population Health (including teaching, student mentoring or supervision, and assessment) and to participate in appropriate training and quality assurance processes for such roles. The above list is not exhaustive and the role-holder is required to undertake such duties as may reasonably be requested within the scope of the post. All staff are required to act in a professional, cooperative and flexible manner, in line with the requirements of the post. Oncology Research Fellow - job description, August 2024 4 Selection criteria Essential           This post must be held in conjunction with an honorary (non-stipendiary) contract with a relevant NHS Trust (obtaining a contract can be supported for successful applicants). Applicants must be medically qualified, GMC registered with a valid licence to practice. Applicants must also be a Member or Fellow of a relevant Royal College (or equivalent). Good grounding in oncology ie for clinical oncologists, FRCR part 1 or equivalent; for medical oncologists, a national medical oncology training number or equivalent. The ability to work independently and to show initiative The ability to work within a team Excellent communication skills Excellent organizational and presentation skills Willing to travel when required Ability to work accurately, with an understanding of the importance of attention to detail Desirable    An interest in the reliable evaluation of treatment An interest in epidemiology Ability to use databases Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures. How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Oncology Research Fellow - job description, August 2024 5 Please upload your CV and supporting statement as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of illhealth/disability. Priority candidates are issued with a redeployment letter by their employing departments. If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Help and support is available from the HR Systems Recruitment support webpage. If you require any further assistance please email the Recruitment Support team. To return to the online application at any stage, please go to the University’s recruitment website. Please note that you will receive an automated email from our e-recruitment system to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants. The University’s Policy on Data Protection is available on the University’s Compliance webpages. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. Oncology Research Fellow - job description, August 2024 6 There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. Oncology Research Fellow - job description, August 2024 7 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see the Childcare Services webpages. Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see the Disability Support webpages. Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information on the Equality and Diversity at Oxford webpages. The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. 8
Notation3 description of Oncology Research Fellow
174658 - Clinical Oncology Research Fellow - JD
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Oxford Population Health (Nuffield Department of Population Health) contains world-renowned population health research groups and provides an excellent environment for multi-disciplinary research and teaching. The Clinical Trial Service Unit (CTSU) is a major international research institute within NDPH, and is one of the world’s leading centres for research into chronic diseases, especially heart disease, kidney disease and cancer. We are seeking a Clinical Research Fellow to work in a Cancer Research UK funded research programme that aims to quantify the benefits and risks of cancer treatments. This post would suit either a medical or clinical oncologist. The main role will be to quantify the risks from one or more systematic therapies using large-scale data in randomised trials. The post-holder will use their oncology expertise to identify relevant trials and extract data. These data will be analysed in partnership with statisticians within the team to produce dose-response relationships. The risks from systematic therapy can then be compared with the benefits, to inform clinical decisions for patients today. The post-holder may also provide oncology input to some of the other ongoing studies and meta-analyses being conducted within the group. This post must be held in conjunction with an honorary (non-stipendiary) contract with a relevant NHS Trust. To be considered for this role you will be medically qualified, GMC registered with a valid licence to practice and a Member or Fellow, of a relevant Royal College (or equivalent). You will also have a good grounding in oncology: for clinical oncologists, FRCR part 1 or equivalent; for medical oncologists, a national medical oncology training number or equivalent. You will have strong organisational and communication skills and an ability to work with attention to detail. The post is full time (although part time will be considered) and fixed term for 2 years in the first instance. Subject to passing selection criteria, there may be an opportunity for candidates to study for a DPhil. **The closing date for applications is noon on Friday, 27 September 2024.** **You will be required to upload a CV and a cover letter as part of your online application. The cover letter should clearly describe how you meet each of the selection criteria listed in the job description.**
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Salary: Grade E63 or E64: £32,398 - £63,152 per annum dependent on qualifications and experience, in line with current pay protection and transitional arrangements in the NHS
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