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Description of Postgraduate Research Associate in Biocatalytic Reductions
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About the role Applications are invited for a Postgraduate Research Associate in Biocatalytic Reductions to work under the supervision of Professor Kylie Vincent for a period of up to 12 months. The project involves developing and exploring biocatalytic approaches to reduction of unsaturated nitrogen-containing functional groups and is funded by the European Research Council and the BBSRC. Find out more about the research and the Vincent group at: http://vincent.chem.ox.ac.uk/ About you Applicants must hold a Degree in Chemistry (or be close to completion) prior to taking up the appointment. The research requires experience in analytical chemistry, particularly proton NMR spectroscopy for product analysis. Ideally you will have experience of biocatalysis and hydrogenation reactions. You will be an effective team-worker, be able manage your own research and administrative activities and have excellent communication skills. The post will be based in the Department of Chemistry, Inorganic Chemistry Laboratory and is available as soon as possible. Application Process Applications for this vacancy are to be made online and you will be required to upload a cover letter, and a CV, as part of your application. In your cover letter (no more than 2 pages), please explain how you meet each of the selection criteria found in the job description. Your CV should also be no more than 2 pages. Certificates, references and research papers should not be provided at this stage. The closing date for applications is 12.00 midday, 21th August 2024, UK time. The University of Oxford and The Department of Chemistry are Silver Athena SWAN holders. Applications are particularly welcome from women and black and ethnic minority candidates, who are under-represented in Chemistry research posts in Oxford.
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Job Description DEPARTMENT OF CHEMISTRY Summary Job title Postgraduate Research Associate in Biocatalytic Reductions Division Mathematical, Physical and Life Sciences Department Department of Chemistry Location Inorganic Chemistry Laboratory Grade and salary Grade 6: £32332- £ 38205 Hours Full time Contract type Fixed-term for a period of up to 12 months Reporting to Prof. Kylie Vincent, Professor in Inorganic Chemistry Vacancy reference 174810 Additional information The post is available immediately. Research topic The project involves developing and exploring biocatalytic approaches to reduction of unsaturated nitrogen-containing functional groups Principal Investigator / supervisor Prof. Kylie Vincent http://vincent.chem.ox.ac.uk/ Project team Project web site www.ox.ac.uk/ Funding partner The funds supporting this research project are provided by the European Research Council and the BBSRC Recent publications https://chemrxiv.org/engage/chemrxiv/articledetails/65b2956ae9ebbb4db9f9e7dc The role This role forms part of a research effort to develop H2-driven strategies for enzyme-catalysed chemical synthesis, using a biocatalysis platform developed in the Vincent group. This post is for a period of up to 12 months and involves development of this reaction system to expand the scope for biocatalytic reduction reactions. The successful candidate will support the project team and also be responsible for a discrete area of research. The candidate should have previous laboratory experience in biocatalysis, hydrogenation reactions and analytical chemistry as well as strong background knowledge in organic chemistry. This role is embedded in a multidisciplinary team and has industrial collaborators. As such, the successful candidate must have a proven track record as a highly effective team member. This role offers the possibility to learn a range of new techniques and candidates should show willingness to learn and implement new skills. . Responsibilities 1. Manage own research and administrative activities, within guidelines provided by senior colleagues. 2. Contribute to wider project planning, including ideas for new research projects 3. Determine the most appropriate methodologies to test hypotheses, and identify suitable alternatives if technical problems arise 4. Select, follow, and adapt experimental protocols 5. Gather, analyse, and present scientific data from a variety of sources 6. Contribute to scientific reports, patent applications and journal articles 7. Contribute to general laboratory management and administration, including stock control of laboratory consumables 8. Use specialist scientific equipment in a laboratory environment 9. Represent the research group at external meetings/seminars, either with other members of the group or alone 10. Manage sensitive or confidential information and intellectual property appropriately Selection criteria Essential selection criteria ● Hold, or be close to completing, a degree in Chemistry together with relevant research experience. job-description-and-selection-criteria-template-april 2024 KAV Research Assistant.docx 2 ● Have significant experience in analytical methods in chemistry, particularly proton NMR spectroscopy. ● Possess strong background knowledge in organic chemistry, and knowledge of biocatalysis, hydrogenation reactions and product identification. ● Have a proven ability to manage own research and administrative activities, and to play an active role in general laboratory management ● Have excellent communication skills, including the ability to write text and prepare figures that can be published, present data at conferences, and represent the research group at meetings ● Have experience of following and adapting protocols and selecting appropriate experimental methodologies from the literature ● Be enthusiastic about learning new techniques ● Have some awareness of how to treat sensitive intellectual property or ‘know-how’ ● Experience of working in a research team, contributing ideas for new research projects . Desirable selection criteria ● Experience in biocatalysis ● Experience of running hydrogenation reactions Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: job-description-and-selection-criteria-template-april 2024 KAV Research Assistant.docx 3 • Work with any substance which has any of the following pictograms on their MSDS: About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Department Of Chemistry The mission of Oxford Chemistry is to advance the global understanding of chemistry and to use that knowledge to address major challenges for society. Oxford Chemistry maintains world-class strengths in fundamental research, including the training of outstanding young scientists, whilst being an outward-looking department engaging with other disciplines, industry, public services, government and the general public. We are a large department within the University’s Mathematical, Physical and Life Sciences Division with over 70 research groups and 900 researchers including 400 graduate research students. Our MChem degree takes 180 students a year and features the distinctive tutorials of Oxford, an innovative three-year programme of practical teaching within our state-of-the-art teaching laboratory, and a 4th year focused on research based within one of our research groups. Research in Oxford Chemistry focuses on fundamental science aimed at making significant and sustained long-term impact. We provide an environment that enables research by hiring, developing, and supporting talented researchers, many recognised as international leaders, across the spectrum of the chemical sciences. Our students and staff work in excellent research facilities to deliver field-leading research that crosses traditional boundaries and engages strongly with other disciplines, both within Oxford and across a range of external sectors. job-description-and-selection-criteria-template-april 2024 KAV Research Assistant.docx 4 The impact of our research in the wider economy and society is manifest in our many industrial and clinical collaborations and successful start-ups. Our eight research themes and business engagements showcase the breadth and depth of our research across the chemical sciences. We are committed to providing an inclusive and supportive work and study environment for all our staff and students based on core values of respect, equality and collaboration. We have held an Athena SWAN silver award since 2015 reflecting our commitment to improving gender equality within our discipline. Oxford Chemistry is accommodated within five buildings in the University’s science area, including a modern RIBA award-winning dedicated research facility and a state-of-the-art practical teaching laboratory. Researchers are supported by a research infrastructure within Chemistry that includes NMR, Mass Spectrometry, Crystallography, Surface Analysis, Inorganic Materials Characterisation, Advanced Electron Spin Resonance and high-performance computing facilities as well as access to facilities across the wider University and at national research facilities including the Rosalind Franklin Institute and Diamond Light Source. To support the Teaching and Research in the Department, there are a number of administrative functions including Finance, Human Resources, Facilities, Information Technology, Student Administration, Health and Safety, Communications and Alumni Relations. Find out more about the Department, our work and our people at chem.ox.ac.uk Equality, Diversity and Inclusion in Oxford Chemistry We are committed to promoting an inclusive and diverse community of students and staff based on core values of respect, equality and collaboration. The Department has an active Equality, Diversity and Inclusion (EDI) committee and since 2015 we have held an Athena SWAN silver award in recognition of our efforts to introduce organisational and cultural practices which promote gender equality and create a better working environment for all. We promote familyfriendly policies and support flexible working arrangements where possible. For more information about the University’s family friendly benefits, please also see https://hr.admin.ox.ac.uk/information-for-parents-and-carers Mathematical, Physical and Life Sciences Division The academic administration of the University is conducted through four divisions (Humanities, Social Sciences, Mathematical, Physical and Life Sciences, and Medical Sciences). The Mathematical, Physical and Life Sciences Division consists of ten constituent departments: The Department of Chemistry, the Department of Computer Science, the Department of Earth Sciences, the Department of Engineering Science, the Department of Materials, Mathematical Institute, the Department of Physics, Department of Plant Sciences, Department of Zoology and the Department of Statistics. The division provides a framework for interdisciplinary teaching and research. There are also links with the Medical Sciences Division. The disciplines within the MPLS Division regularly appear at the highest levels in rankings, including the Times Higher Education and QS world rankings. Nationally, the quality of the job-description-and-selection-criteria-template-april 2024 KAV Research Assistant.docx 5 Division’s research outputs and environment, and the resulting impact, was recognised through strong performances in the UK Research Excellence Framework in both 2014 and 2021. For more information please visit: http://www.mpls.ox.ac.uk/ How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs Non-technical questions about this job should be addressed to the recruiting department directly recuitment@chem.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. job-description-and-selection-criteria-template-april 2024 KAV Research Assistant.docx 6 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82 of 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependants. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service job-description-and-selection-criteria-template-april 2024 KAV Research Assistant.docx 7 offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. Oxford Research Staff Society (OxRSS) A society run by and for Oxford University research staff. It offers researchers a range of social and professional networking opportunities. Membership is free, and all researchers employed by Oxford University are welcome to join. Subscribe at researchstaff-subscribe@maillist.ox.ac.uk to join the mailing list to find out about upcoming events and other information for researchers, or contact the committee on committee@oxrss.ox.ac.uk. For more information, see www.ox.ac.uk/oxrss, Twitter @ResStaffOxford, and Facebook www.facebook.com/oxrss. job-description-and-selection-criteria-template-april 2024 KAV Research Assistant.docx 8
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**About the role** Applications are invited for a Postgraduate Research Associate in Biocatalytic Reductions to work under the supervision of Professor Kylie Vincent for a period of up to 12 months. The project involves developing and exploring biocatalytic approaches to reduction of unsaturated nitrogen-containing functional groups and is funded by the European Research Council and the BBSRC. _Find out more about the research and the Vincent group at:_ http://vincent.chem.ox.ac.uk/ **About you** Applicants must hold a Degree in Chemistry ( **or be close to completion** ) prior to taking up the appointment. The research requires experience in analytical chemistry, particularly proton NMR spectroscopy for product analysis. Ideally you will have experience of biocatalysis and hydrogenation reactions. You will be an effective team-worker, be able manage your own research and administrative activities and have excellent communication skills. The post will be based in the Department of Chemistry, Inorganic Chemistry Laboratory and is available as soon as possible. **Application Process** Applications for this vacancy are to be made online and you will be required to upload a cover letter, and a CV, as part of your application. In your cover letter (no more than 2 pages), please explain how you meet each of the selection criteria found in the job description. Your CV should also be no more than 2 pages. **Certificates, references and research papers should not be provided at this stage.** The closing date for applications is 12.00 midday, 21th August 2024, UK time. The University of Oxford and The Department of Chemistry are Silver Athena SWAN holders. Applications are particularly welcome from women and black and ethnic minority candidates, who are under-represented in Chemistry research posts in Oxford.
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