_________________________________________________________________________ Job description and selection criteria Job title Medical Statistician Division Medical Sciences Department Paediatrics Location Oxford Vaccine Group, CCVTM, Churchill Hospital, Oxford. Partial hybrid working may be possible for this post. Grade and salary Grade 7: £38,674 - £46,913 per annum (with a discretionary range to £51,059 per annum) Hours Full-time (Part-time and flexible working arrangements may be considered) Contract type Fixed-term (2 years) Reporting to Prof Xinxue Liu (Associate Professor of Medical Statistics and Epidemiology, Prof Merryn Voysey (Professor of Statistics in Vaccinology) Vacancy reference 176341 Additional information Applications are to be made online, please see the advert for the closing date. Principal Investigator / Prof Xinxue Liu, Prof Merryn Voysey supervisor Project team Oxford Vaccine Group Project web site www.ox.ac.uk/ http://www.ovg.ox.ac.uk/ Funding partner The funds supporting this research project are provided by Nipah CEPI The role The post holder will join a large group of researchers at the Oxford Vaccine Group, conducting major national and international studies of vaccines for children and adults. We seek a self-motived medical statistician to join our large team of bioinformaticians, epidemiologists and statisticians and to work on clinical observational studies and national/international clinical trials of vaccines and infectious diseases. You will have excellent communication skills and a commitment to producing accurate and appropriate analyses in a timely fashion. Strong analytical skills, an enquiring and flexible attitude, and an interest in working collaboratively with researchers from different disciplines will also be important components for success. It is desirable that candidates have a PhD in a relevant discipline. However, candidates with relevant experience but no PhD are encouraged to apply also. Candidates who perform well in the post can complete a PhD within the department as part of their role, with an 80% reduction in fees subject to departmental approval. Flexible working The postholder will be based at the Oxford Vaccine Group, CCVTM, Churchill Hospital, Oxford, however, partial hybrid working may be possible. The post is offered as full-time, but part-time and flexible working arrangements may be considered with a minimum of 22.5 weekly hours. Responsibilities • Provide statistical advice and explanations of statistical issues within a multi-disciplinary team including: clinical scientists, trial managers, data managers, microbiologists and other researchers. • Contribute to the preparation of new clinical research proposals, such as sample size calculation and validation. • Contribute to protocol development and ethics committee submissions. • Contribute to the statistical review of all Case Report Forms and other data collection tools required. • Generate and validate randomisation schedules as required. • Contribute to the management of study databases, such as checking, validation and cleaning data to remove inaccuracies or errors. • Develop and review statistical analysis plans (SAP). • Take the lead on all the detailed analyses relating to your assigned studies. • Contribute to the dissemination of research findings via peer reviewed publications. • Present work at regional, national or international scientific meetings. • Commitment to training and developing new skills and methods where needed. • Develop methodological research in collaboration with members of OVG or external collaborators. Participate in the wider work of the Oxford Vaccine Group, such as journal clubs, and weekly meetings. • Department of Paediatrics, 176341, Medical Statistician – Job Description 2 Selection criteria Essential • • • • • • • • • Hold a post-graduate qualification in statistics/epidemiology or a relevant field, or substantial relevant experience. Experience of analysing large datasets from clinical trials or other well-designed studies to address clinically relevant health-related questions. Demonstrated ability to write programs in at least one statistical software such as Stata, SAS, or R. Experience of writing up statistical analysis plan (SAP) for clinical trials. Experience of writing up results of statistical analyses and contributing to peer-reviewed papers. Demonstrated ability to work successfully with individuals from different disciplines. Excellent verbal and written communication skills, including the ability to communicate statistical concepts clearly to a non-statistical audience. Ability to manage and prioritise own workload. Ability to work to tight deadlines calmly and efficiently. Desirable • • • • • • Hold a PhD/DPhil in statistics/epidemiology or a relevant field. Experience of working on vaccine or infectious disease related research studies. Experience of designing clinical trials and observational studies. Experience of carrying out advanced statistical analyses (e.g. multilevel modelling, imputation of missing data, etc.) as a statistician supporting clinical trials or other well designed studies. Experience in contributing to grant proposals for research funding. Publication record with first authorship. . Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. If you have previously worked for the University we will also verify key information such as your dates of employment and reason for leaving your previous role with the department/unit where you worked. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Department of Paediatrics, 176341, Medical Statistician – Job Description 3 Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • Lone Working due to hybrid working Additional security pre-employment checks This job includes duties that will require additional security pre-employment checks: • A satisfactory basic Disclosure and Barring Service check due to the nature of this position working with highly sensitive data. • University security screening (e.g. identity checks) About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. The Oxford Vaccine Group The Oxford Vaccine Group (OVG) is led by Andrew J Pollard, Professor of Paediatric Infection and Immunity. Staff re based within a purpose-built centre on the Churchill Hospital site and form part of the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM). The aim of OVG is to co-ordinate expertise in the study of microbial diseases and the immune response to microbes, in order to facilitate research on the development and implementation of vaccines. This may Department of Paediatrics, 176341, Medical Statistician – Job Description 4 include new, improved or combined vaccines for the adult and paediatric population. There is currently a large focus on delivering the COVID-19 vaccine trials. Core group members include two Consultants in Vaccinology, a Director of Clinical Trials, a Senior Clinical Trials Manager, adult and paediatric clinical research fellows, adult and paediatric research nurses, project managers, QA manager, IT manager, and an administration team. The Infection and Immunity Laboratory includes post doctorate scientists, research assistants and DPhil students. Wider group members include professionals from a range of specialities including immunologists, microbiologists, statisticians, a community paediatrician, the local Health Protection team and a bioethicist. Recent studies carried out by the group include: • • • • • COVID vaccine trials (Phase 1, 2 and 3), Heterologous regimens and booster studies Vaccines against RSV Pneumococcal nasopharyngeal carriage epidemiology Meningococcal B vaccine development and evaluation Development of a typhoid challenge model More information about OVG may be found at the website: http://www.ovg.ox.ac.uk Department of Paediatrics The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. Our work spans from early proof-of concept fundamental science, all the way up to its application in clinical settings. We continue to shape the landscape of medical science through positively impacting the lives of millions of children from our global research programmes, academic resources, and commitment to success. Our broad research base positions the department in a pivotal role and subsequently a world leader in child health. With research facilitates in the UK and abroad, we work on a global scale, building a paediatric network in the medical science community. We are committed to inform and inspire external audiences worldwide through our public engagement and outreach activities. In 2021, we successfully administered a grant value of £130,895,28 obtained through 168 projects. Our strong relationship with funding bodies have also been a contributor to the successes and milestones in children’s health research. With strong support from the Wellcome Trust, NIH, Cancer Research UK, UKRI, MDUK, Bill & Melinda Gates Foundation, Academy of Medical Sciences and the NIHR, we have employed 360+ staff, researchers, and students. These figures continue to grow as we expand our activities to overcome the multitude of challenges within children’s research health. For more information please visit: http://www.paediatrics.ox.ac.uk/ The Department of Paediatrics holds a Gold Athena Swan award to recognise advancement of gender equality: representation, progression and success for all. Department of Paediatrics, 176341, Medical Statistician – Job Description 5 Medical Sciences Division We are an internationally recognized centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: http://www.medsci.ox.ac.uk/ Department of Paediatrics, 176341, Medical Statistician – Job Description 6 How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two/three referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that: • • as part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting https://staff.web.ox.ac.uk/recruitment-support-faqs advice is available at: Non-technical questions about this job should be addressed to the recruiting department directly at recruitment@paediatrics.ox.ac.uk or using the contact details in the online advertisement. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our e-recruitment system to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Department of Paediatrics, 176341, Medical Statistician – Job Description 7 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82 of 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. Department of Paediatrics, 176341, Medical Statistician – Job Description 8 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts including salary sacrifice schemes for bicycles and electric cars and other discounts. Staff can access a huge range of personal and professional development opportunities. See https://hr.admin.ox.ac.uk/staff-benefits. Employee Assistance Programme As part of our wellbeing offering staff get free access to Health Assured, a confidential employee assistance programme, available 24/7 for 365 days a year. Find out more https://staff.admin.ox.ac.uk/health-assured-eap. University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/. There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme. Family-friendly benefits We are a family-friendly employer with one of the most generous family leave schemes in the Higher Education sector (see https://hr.web.ox.ac.uk/family-leave). Our Childcare Services team provides guidance and support on childcare provision, and offers a range of high-quality childcare options at affordable prices for staff. In addition to 5 University nurseries, we partner with a number of local providers to offer in excess of 450 full time nursery places to our staff. Eligible parents are able to pay for childcare through salary sacrifice, further reducing costs. See https://childcare.admin.ox.ac.uk/. Supporting disability and health-related issues (inc menopause) We are committed to supporting members of staff with disabilities or long-term health conditions, including those experiencing negative effects of menopause. Information about the University’s Staff Disability Advisor, is at https://edu.admin.ox.ac.uk/disability-support. For information about how we support those going through menopause see https://hr.admin.ox.ac.uk/menopauseguidance. Staff networks The University has a number of staff networks including for research staff, BME staff, LGBT+ staff, disabled staff network and those going through menopause. Find out more at https://edu.admin.ox.ac.uk/networks. Department of Paediatrics, 176341, Medical Statistician – Job Description 9 The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. Research staff The Researcher Hub supports all researchers on fixed-term contracts. They aim to help you settle in comfortably, make connections, grow as a person, extend your research expertise and approach your next career step with confidence. Find out more https://www.ox.ac.uk/research/support-researchers/researcher-hub. Oxford’s Research Staff Society is a collective voice for our researchers. They also organise social and professional networking activities for researchers. Find out more https://www.ox.ac.uk/research/support-researchers/connecting-other-researchers/oxfordresearch-staff-society. Department of Paediatrics, 176341, Medical Statistician – Job Description 10
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Standard Grade 7: 38,674 - 46,913 with a discretionary range to £51,059 per annum (pro-rata)
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About the role We have an exciting opportunity to join the Oxford Vaccine Group in the Department of Paediatrics as our Medical Statistician. You will play an important role in applying cutting-edge methodologies to the design and analysis of vaccine clinical trials and observational studies. You will be responsible for all the statistical activities in your assigned projects, including supporting new research proposals, developing relevant sections of study protocols, leading statistical analyses and reports, creating statistical analysis plans, and drafting the relevant sections of manuscripts. You will be working in a growing department within the Medical Sciences Division. The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. Specifically, you will join the Oxford Vaccine Group Quantitative Research team comprising more than 15 researchers with expertise in statistics, epidemiology, and bioinformatics. The quantitative research team is dedicated to advancing global health through innovative quantitative methods. We work at the forefront of clinical trials and observational studies, collaborating with leading national and international organisations to shape vaccine strategies and public health policies. Our team played a pivotal role in the design and analysis of the landmark ChAdOx1 nCoV-19 (AZD1222) trial, contributing to its World Health Organization Emergency Use Listing (EUL) and emergency authorisations worldwide. If you are passionate about conducting high-impact research that drives meaningful change, we encourage you to apply. We have multiple vacancies available and invite you to apply for the position that best matches your skills and interests. Should the hiring panel believe that your skills and experience better align with an alternative vacancy, your application may be considered for an alternative role. This position is offered full-time on a fixed-term contract initially for two years with the possibility to extend provided further external funding is available. Part-time applications may be considered (with a minimum of 22.5 weekly hours). About the department The Department of Paediatrics holds the Athena Swan Gold Award (a national gender equality charter) acknowledging the innovative policies and practices developed across the department. We encourage staff to develop their skills by offering all staff ten paid days of professional development each year and have a policy where staff can apply to receive funding for further training courses to support their professional development. For staff on work visas, we also offer financial assistance towards visa renewal fees. Please visit our website to find out more about the Department. About you It is desirable that you have a PhD in a relevant discipline, such as Statistics, Epidemiology, Mathematics or Bioinformatics. However, if you have relevant experience but no PhD, you are encouraged to apply also. The department offers DPhil opportunities to staff as part of their role if meeting enrolment criteria, with an 80% reduction in fees. You will have highly effective verbal and written communication skills with all levels of staff and an ability to operate effectively in a demanding and collaborative research environment. Application Process You will be required to upload a CV and Supporting Statement as part of your online application. The Supporting Statement should include a cover letter and should also clearly describe how you meet each of the selection criteria listed in the job description. Click here for information and advice on writing an effective Supporting Statement. To discuss the post in more detail, please contact Prof Merryn Voysey, the Head of Statistics in Vaccinology, using the contact details below. Only online applications received before 12.00 midday on Friday 14 March 2025 will be considered. Interviews will be held as soon as possible thereafter.
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**About the role ** We have an exciting opportunity to join the Oxford Vaccine Group in the Department of Paediatrics as our Medical Statistician. You will play an important role in applying cutting-edge methodologies to the design and analysis of vaccine clinical trials and observational studies. You will be responsible for all the statistical activities in your assigned projects, including supporting new research proposals, developing relevant sections of study protocols, leading statistical analyses and reports, creating statistical analysis plans, and drafting the relevant sections of manuscripts. You will be working in a growing department within the Medical Sciences Division. The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. Specifically, you will join the Oxford Vaccine Group Quantitative Research team comprising more than 15 researchers with expertise in statistics, epidemiology, and bioinformatics. The quantitative research team is dedicated to advancing global health through innovative quantitative methods. We work at the forefront of clinical trials and observational studies, collaborating with leading national and international organisations to shape vaccine strategies and public health policies. Our team played a pivotal role in the design and analysis of the landmark ChAdOx1 nCoV-19 (AZD1222) trial, contributing to its World Health Organization Emergency Use Listing (EUL) and emergency authorisations worldwide. If you are passionate about conducting high-impact research that drives meaningful change, we encourage you to apply. _We have multiple vacancies available and invite you to apply for the position that best matches your skills and interests. Should the hiring panel believe that your skills and experience better align with an alternative vacancy, your application may be considered for an alternative role._ This position is offered full-time on a fixed-term contract initially for two years with the possibility to extend provided further external funding is available. Part-time applications may be considered (with a minimum of 22.5 weekly hours). **About the department ** The Department of Paediatrics holds the Athena Swan Gold Award (a national gender equality charter) acknowledging the innovative policies and practices developed across the department. We encourage staff to develop their skills by offering all staff ten paid days of professional development each year and have a policy where staff can apply to receive funding for further training courses to support their professional development. For staff on work visas, we also offer financial assistance towards visa renewal fees. Please visit our website to find out more about the Department. **About you ** It is desirable that you have a PhD in a relevant discipline, such as Statistics, Epidemiology, Mathematics or Bioinformatics. However, if you have relevant experience but no PhD, you are encouraged to apply also. The department offers DPhil opportunities to staff as part of their role if meeting enrolment criteria, with an 80% reduction in fees. You will have highly effective verbal and written communication skills with all levels of staff and an ability to operate effectively in a demanding and collaborative research environment. **Application Process ** You will be required to upload a CV and Supporting Statement as part of your online application. The Supporting Statement should include a cover letter and should also clearly describe how you meet each of the selection criteria listed in the job description. Click here for information and advice on writing an effective Supporting Statement. To discuss the post in more detail, please contact Prof Merryn Voysey, the Head of Statistics in Vaccinology, using the contact details below. **Only online applications received before 12.00 midday on Friday 14 March 2025 will be considered. Interviews will be held as soon as possible thereafter.**
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