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Research Assistant
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based near: Wellcome Trust Centre Clinical Vaccinology and Tropical Medicine
application closing date: 2025-01-15T12:00:00+00:00
comment: **About the role** We have an exciting opportunity to join Prof Matthew Woods Research Group the Department of Paediatrics as our Research Assistant. The Wood laboratory focuses on developing molecular therapies for disorders of the nervous system and muscle. Our objectives include understanding disease biology, identifying and validating therapeutic targets, and developing gene- based nucleic acid therapeutic platforms. The laboratory uses in vitro and animal models to evaluate these platforms and simultaneously develops advanced delivery technologies to target relevant tissues and cells, such as skeletal muscle, heart, and nervous system. The laboratory has developed novel oligonucleotide and RNA editing therapies for neuromuscular disorders, including Duchenne Muscular Dystrophy (DMD), Myotonic Dystrophy type 1 (DM1), Spinal Muscular Atrophy (SMA) and Spinal and Bulbar Muscular Atrophy (SBMA). The group has also developed extracellular vesicle nanotechnologies for targeted cell delivery and discovered delivery technologies, including peptide and antibody-based technologies. Research in the laboratory also includes studying fundamental RNA biology and developing RNA-based therapeutic agents and novel technologies for their delivery You will be working in a growing department within the Medical Sciences Division. The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. This position is offered full-time on a fixed-term contract initially until 31/10/2025 with the possibility to extend provided further external funding is available. **About the department** The Department of Paediatrics holds the Athena Swan Gold award (a national gender equality charter) acknowledging the innovative policies and practices developed across the department. We encourage staff to develop their s…
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contact: Amarjit Bhomra
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comment: About the role We have an exciting opportunity to join Prof Matthew Woods Research Group the Department of Paediatrics as our Research Assistant. The Wood laboratory focuses on developing molecular therapies for disorders of the nervous system and muscle. Our objectives include understanding disease biology, identifying and validating therapeutic targets, and developing gene-based nucleic acid therapeutic platforms. The laboratory uses in vitro and animal models to evaluate these platforms and simultaneously develops advanced delivery technologies to target relevant tissues and cells, such as skeletal muscle, heart, and nervous system. The laboratory has developed novel oligonucleotide and RNA editing therapies for neuromuscular disorders, including Duchenne Muscular Dystrophy (DMD), Myotonic Dystrophy type 1 (DM1), Spinal Muscular Atrophy (SMA) and Spinal and Bulbar Muscular Atrophy (SBMA). The group has also developed extracellular vesicle nanotechnologies for targeted cell delivery and discovered delivery technologies, including peptide and antibody-based technologies. Research in the laboratory also includes studying fundamental RNA biology and developing RNA-based therapeutic agents and novel technologies for their delivery You will be working in a growing department within the Medical Sciences Division. The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. This position is offered full-time on a fixed-term contract initially until 31/10/2025 with the possibility to extend provided further external funding is available. About the department The Department of Paediatrics holds the Athena Swan Gold award (a national gender equality charter) acknowledging the innovative policies and practices developed across the department. We encourage staff to develop their skills by …
further particulars: 176908 Research Assistant Wood Job Description
salary: Research Grade 6: 34,982 - 40,855 with a discretionary range to £45,628 per annum (pro-rata)
application opening date: 2024-12-18T09:00:00+00:00
subject: research

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176908 Research Assistant Wood Job Description
value: _________________________________________________________________________ Job description and selection criteria Job title Research Assistant Division Medical Sciences Department Paediatrics Location Department of Paediatrics, Wood Research Group, Institute of Developmental & Regenerative Medicine IDRM, Old Road Campus, Oxford Grade and salary Research Grade 6: £34,982 - £40,855 per annum (with a discretionary range to £45,628 per annum) Hours Full-time Contract type Fixed term until 31/10/2025 Reporting to Jennifer Frommer, Development Vacancy reference 176908 Additional information Applications are to be made online, please see the advert for the closing date. Research topic Oligonucleotide therapies for neuromuscular diseases Group Leader - Oligo Chemistry Drug Principal Investigator Prof Matthew Wood / supervisor Project team Wood Group Project web site https://www.paediatrics.ox.ac.uk/research/wood-group Funding partner The funds supporting this research project are provided by the Medical Research Council and LifeArc in partnership with the Nucleic Acid Therapy Accelerator (NATA) Hub. The role The NATA Delivery Research Challenge is a major and prestigious programme of funding awarded to the University from the Medical Research Council and LifeArc in partnership with the Nucleic Acid Therapy Accelerator (NATA) Hub. The promise of nucleic acid therapeutics has been demonstrated in the clinic, however their development and widespread use has been hindered by a lack of robust techniques to achieve targeted delivery to specific tissues, improve stability and facilitate uptake into cells, without compromising safety or effectiveness. The Global Oligonucleotide therapy market is currently worth $1 billion and is expected to reach $1.62 billion in 2025 provided the challenges with targeted delivery are resolved. This programme will support an international consortium working to overcome major barriers to safe and effective delivery through the development of novel te…
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