Research Assistant
application opening date: 2025-01-06T09:00:00+00:00
organization part: Kennedy Institute of Rheumatology
further particulars: Research Assistant JD_Final.pdf
application closing date: 2025-01-31T12:00:00+00:00
spatial: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3 7FY
type: Vacancy
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notation: 177447
formal organization: University of Oxford
comment: We are looking for an energetic and experienced full-time Research Assistant to join the research group of Professor Tal Arnon at the Kennedy Institute in Oxford, to work within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences. The laboratory focuses on the cellular and molecular mechanisms regulating lymphocyte activation and differentiation in vivo. These studies aim to advance our basic understanding of humoral immunity and may have important implications for the development of novel vaccines and therapeutic agents designed to treat a variety of immunological disorders (e.g., allergy, asthma, cancer). The position is suited for an experienced individual that enjoys working in an academic environment and who is keen to support competitive research. For a suitable candidate, who already has a strong scientific background, and who wishes to continue to develop these skills, there will also be an opportunity for academic training, including helping to develop projects addressing novel scientific questions, learning cutting-edge techniques, contributing to publications and enhancing academic skills. You will support the research team in a wide variety of molecular and cellular approaches including flow cytometry analysis, sorting, construct generations, histological analysis, tissue collection, in vivo work etc and routinely liaise with direct supervisor, and other members of group, regarding experiments and general laboratory procedures. You will also contribute to general laboratory maintenance, general laboratory management and administration. You must hold, or be close to graduating with, a BSc (First class or Upper second class, 2.1) or higher degree in Biological Sciences, Immunology, or a related subject (not including pharmacology) with a Home Office personal licence. You must have an extensive experience in handling mice and working with complex mouse models. Previous experience in basic research, preferentially in the field …
salary: Research Grade 6: £34,982 - £40,855 per annum
subject: research
based near: Kennedy Institute of Rheumatology
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Research Assistant JD_Final.pdf
value: Job Description _________________________________________________________________________ Summary Job title Research Assistant Division Medical Sciences Division Department Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Location Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3 7FY Grade and salary Grade 6: £34,982 - £40,855 per annum Hours Full time Contract type Fixed-term (1 year) Reporting to Professor Tal Arnon Vacancy reference 177447 Research topic Spatiotemporal regulation of adaptive immunity during homeostasis and in response to infectious diseases Principal Investigator / supervisor Professor Tal Arnon Project team Project web site https://www.kennedy.ox.ac.uk/team/tal-arnon Funding partner The funds supporting this research project are provided by the MRC 1. Maclean AJ, Bonifacio Lopes JPP, Oram SL, Mohsen MO, Bachmann MF And Arnon TI. Regulation of pulmonary plasma cell responses during secondary infection with influenza. (2023) Journal of Experimental Medicine Jul 1;221(7):e20232014. PMID: 38661717 Recent publications 2. 3. Thornton EE and Arnon TI. It takes a village to skew a lymph node (2022) Immunity Oct 11;55(10):1751-1753. 10.1016/j.immuni.2022.09.008.PMID: 36223721(Preview). doi: 4. MacLean AJ, Richmond N, Koneva L, Attar M, Medina CAP, Thornton E, CruzGomes A, El-Turabi A, Bachmann MF, Rijal P, Tan TK, Townsend A, Sansom SN, Bannard O, and Arnon TI. Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites (2022) Immunity Apr 12;55(4):718-733.e8. doi: 10.1016/j.immuni.2022.03.003. 5. Xie B, Khoyratty TE, Abu-Shah E, Cespedes P, MacLean AJ, Pirgova G, Zhiyuan Hu, Ahmed AA, Dustin ML, Udalova IA and Arnon TI. The zinc finger protein Zbtb18 inhibits differentiation of plasma cells by transcriptionally repressing class I PI3K subunits Journal of Immunology 2021 Apr 1;206(7):1515-1527. doi: 10.4049/jimmunol.200036…
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