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Description of Senior Scientific Researcher in Single-Molecule Biophysics
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Senior Scientific Researcher in Single-Molecule Biophysics
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comment: We are looking to hire an outstanding senior scientific staff member to support our group’s research, which focuses on studying DNA and chromatin replication at the single-molecule level. You will form part of the research team core and support the wider group by leading outstanding research and development in single-molecule biophysics. About the project In this project, you will design and implement novel forms of biophysical instrumentation (e.g. advanced optical tweezers and magnetic tweezers, single-molecule fluorescence, novel single-molecule approaches to DNA sequencing, integration with cryo-EM) with the goal of maximizing their contributions to the understanding of DNA replication and/or chromatin organization. You will propose and/or implement technical advances on single-molecule instruments and use them together with graduate students and postdocs to acquire data on DNA replication and/or chromatin organization. An aptitude in instrumentation development and quantitative biophysics, a willingness to acquire relevant knowledge into the photophysics of fluorescent labels, and an interest in guiding, coaching, and training graduate students and postdocs in their scientific and technical development, are essential. The overall goal is to provide novel and sound single-molecule biophysical insights into DNA replication and/or chromatin organization to advance these exciting fields. Requirements For this innovative, interdisciplinary project, we are looking a (bio)physicist, with: • A successfully completed Ph.D. degree in biophysics or optical physics. • Practical experience and scientific maturity in the above areas. • Strong aptitude and interest in biophysical instrumentation and microscopy, and willingness to acquire related knowledge e.g. photophysics. • Professional experience with force spectroscopy (e.g. optical tweezers, magnetic tweezers, or atomic force microscopy) or single-molecule fluorescence methodologies. • Strong skills in hardware-software …
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comment: We are looking to hire an outstanding senior scientific staff member to support our group’s research, which focuses on studying DNA and chromatin replication at the single-molecule level. You will form part of the research team core and support the wider group by leading outstanding research and development in single-molecule biophysics. **About the project** In this project, you will design and implement novel forms of biophysical instrumentation (e.g. advanced optical tweezers and magnetic tweezers, single- molecule fluorescence, novel single-molecule approaches to DNA sequencing, integration with cryo-EM) with the goal of maximizing their contributions to the understanding of DNA replication and/or chromatin organization. You will propose and/or implement technical advances on single-molecule instruments and use them together with graduate students and postdocs to acquire data on DNA replication and/or chromatin organization. An aptitude in instrumentation development and quantitative biophysics, a willingness to acquire relevant knowledge into the photophysics of fluorescent labels, and an interest in guiding, coaching, and training graduate students and postdocs in their scientific and technical development, are essential. The overall goal is to provide novel and sound single-molecule biophysical insights into DNA replication and/or chromatin organization to advance these exciting fields. **Requirements** For this innovative, interdisciplinary project, we are looking a (bio)physicist, with: • A successfully completed Ph.D. degree in biophysics or optical physics. • Practical experience and scientific maturity in the above areas. • Strong aptitude and interest in biophysical instrumentation and microscopy, and willingness to acquire related knowledge e.g. photophysics. • Professional experience with force spectroscopy (e.g. optical tweezers, magnetic tweezers, or atomic force microscopy) or single-molecule fluorescence methodologies. • Strong skills in hardware-…
further particulars: 177451 - JD Senior Scientific Researcher_ND.pdf
application closing date: 2025-05-31T12:00:00+01:00
type: Vacancy
spatial: Department of Physics, Clarendon Laboratory and Kavli Institute
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application opening date: 2024-12-20T09:00:00+00:00

177451 - JD Senior Scientific Researcher_ND.pdf
value: _________________________________________________________________________ Job Description and Selection Criteria Job title Senior Scientific Researcher in Single-Molecule Biophysics Division Mathematical Physical and Life Sciences Department Physics Location Clarendon laboratory and Kavli institute Grade and salary Grade 9: £55,636 - £64,228 per annum Hours Full time Contract type Fixed term for 2 years with the possibility of extension subject to funding Reporting to Professor Nynke Dekker Vacancy reference 177451 Closing date – midday on 17 January31 May 2025 Additional information The role We are looking to hire an outstanding senior scientific staff member to support our group’s research, which focuses on single-molecule studies of DNA replication, chromatin replication, and chromatin organization. You will form part of the research team core and support the wider group by leading strategic and outstanding research and development in single-molecule biophysics instrumentation. This senior role offers the opportunity to develop groundbreaking instrumentation to advance research in biological physics and to develop and deploy invaluable skills in leadership and interdisciplinary collaboration, all within the vibrant scientific community of the University of Oxford. About the project In this project, you will design and implement novel forms of biophysical instrumentation (e.g. advanced optical tweezers and magnetic tweezers, single-molecule fluorescence, novel single-molecule approaches to DNA sequencing, integration with cryo-EM) with the goal of maximizing their contributions to the understanding of DNA- and chromatin replication and chromatin organization. You will propose and/or implement technical advances on single-molecule instruments and use them together with graduate students and postdocs to acquire data on DNA- and chromatin replication and chromatin organization. An aptitude in biophysical and microscopy instrumentation development and hardware-softwar…
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