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Senior Postdoctoral Research Scientist In Mucosal Immunology
application opening date: 2025-03-12T09:00:00+00:00
comment: About the role We have an exciting opportunity to join the Oxford Vaccine Group in the Department of Paediatrics as our Senior Postdoctoral Research Scientist in Mucosal Immunology. The successful candidate will conduct research in a dynamic and highly collaborative environment of an internationally leading research institute. They will benefit from the institute and wider university expertise in immunology and vaccinology. In this position you will lead development of transcriptomic analysis across several ongoing projects contributing to the identification of mucosal mechanisms involved in protection and susceptibility to respiratory disease as well as vaccine-induced immune responses. You will also use a broad array of T and B cell experimental approaches including ELISpot, flow cytometry, ELISA and sterile cell culture. You will work closely with both laboratory and bioinformatic teams and will be responsible for analysis and/or supervision of the data analyses. You will be expected to write publications for academic journals and raise research funds through grant applications. You will be working in a growing department within the Medical Sciences Division. The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. The Oxford Vaccine Group is a passionate and active research group which conducts world-leading research into creating new and optimising existing vaccines for children and adults. Our research has led to development and licensure of the new Oxford/AstraZeneca SARS-CoV-2 vaccine, by delivering and managing global vaccine trials. We are also working on human challenge models to advance the development of vaccines and therapeutics against several infectious diseases. This position is offered full-time on a fixed-term contract initially for 2 years with the possibi…
application closing date: 2025-04-09T12:00:00+01:00
contact: Daniela Ferreira
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further particulars: 178408 Senior Postdoctoral Research Scientist in Mucosal immunology Job Description G8
salary: Research Grade 8: 48,235 - 57,255 per annum (with a discretionary range to £64,228 per annum)
comment: **About the role** We have an exciting opportunity to join the Oxford Vaccine Group in the Department of Paediatrics as our Senior Postdoctoral Research Scientist in Mucosal Immunology. The successful candidate will conduct research in a dynamic and highly collaborative environment of an internationally leading research institute. They will benefit from the institute and wider university expertise in immunology and vaccinology. In this position you will lead development of transcriptomic analysis across several ongoing projects contributing to the identification of mucosal mechanisms involved in protection and susceptibility to respiratory disease as well as vaccine-induced immune responses. You will also use a broad array of T and B cell experimental approaches including ELISpot, flow cytometry, ELISA and sterile cell culture. You will work closely with both laboratory and bioinformatic teams and will be responsible for analysis and/or supervision of the data analyses. You will be expected to write publications for academic journals and raise research funds through grant applications. You will be working in a growing department within the Medical Sciences Division. The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology. The Oxford Vaccine Group is a passionate and active research group which conducts world-leading research into creating new and optimising existing vaccines for children and adults. Our research has led to development and licensure of the new Oxford/AstraZeneca SARS-CoV-2 vaccine, by delivering and managing global vaccine trials. We are also working on human challenge models to advance the development of vaccines and therapeutics against several infectious diseases. This position is offered full-time on a fixed-term contract initially for 2 years with the pos…

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value: _________________________________________________________________________ Job description and selection criteria Job title Senior Postdoctoral Research Scientist in Mucosal Immunology Division Medical Sciences Department Paediatrics Location Oxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine & Institute of Developmental and Regenerative Medicine, Headington, Oxford Grade and salary Research Grade 8: £48,235 - £57,255 per annum (with a discretionary range to £64,228 per annum) Hours Full-time Contract type Fixed-term (2 years) Reporting to Daniela Ferreira, Professor of Vaccinology Vacancy reference 178408 Additional information Applications are to be made online, please see the advert for the closing date. Research topic Immune responses to respiratory human challenge and vaccination Principal Investigator Prof Daniela Ferreira / supervisor Project team Controlled human infection models and mucosal immunity Project web site https://www.ovg.ox.ac.uk/ Funding partner The funds supporting this research project are provided by CEPI The role Controlled human infection models (CHIMs) are pivotal to advance the development of vaccine as they are used for proof of concept, pathogenesis, down-selection and immunogenicity studies. Using the CHIM with Streptococcus pneumoniae (pneumococcus), RSV and Flu the team has conducted over 30 independent clinical studies, including vaccine studies, genetic modified strains, at risk populations and co-infection studies with over 2000 participants inoculated to date. We have an exciting opportunity for a Senior Postdoctoral Research Scientist in Mucosal Immunology to work on CHIMs with respiratory pathogens (pneumococcus, RSV, influenza) on projects funded by Horizon, Wellcome Trust and industry. Each project involves the identification of mucosal mechanisms involved in protection and susceptibility to disease as well as vaccineinduced immune responses. The potholder will lead development of several assays for mu…
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