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178712 Research Associate Gr 7 JD - Fisher
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value: ____________________________________________________________________________ DEPARTMENT OF BIOCHEMISTRY Job Description Job title Postdoctoral Research Associate in flow cytometric preparation and analysis of mitotic chromosomes Division Medical Sciences Department Biochemistry Location Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford, OX1 3QU Grade and salary Grade 7: £41,997 - £46,913 per annum Hours Full Time (37.5 hours per week) Contract type Fixed Term Contract for up to 6 months in the first instance Reporting to Professor Amanda Fisher Vacancy reference 178712 Additional information You are required to submit a CV and a supporting statement with your application, outlining how you meet each of the selection criteria for the role (see below for details). Your application will not be processed if you do not include both documents. This role meets the criteria for sponsorship under the Skilled Worker visa. The University will meet the cost of the Skilled Worker (or if suitable, a Global Talent) visa and NHS surcharge for applicants that require a visa. Research topic Flow cytometric preparation and analysis of mitotic chromosomes Principal Investigator / supervisor Amanda Fisher (with technical support from Bhavik Patel) Project team Cell identity and Epigenetic Inheritance group (@bioch.ox.ac.uk) Epigenetic Memory group (@lms.mrc.ac.uk) Project web site https://fishergroup.web.ox.ac.uk/home Funding partner MRC (Medical Research Council) Recent publications Djeghloul D, Patel B, Kramer H, Dimond A, Whilding C, Brown K, Kohler A, Feytout A, Veland N, Elliott J, Bharat TAM, Tarafder AK, Löwe J, Ng BL, Guo Y, Guy J, Huseyin MK, Klose RJ, Merkenschlager M, Fisher AG. (2020). Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction. Nature Communications 11, 4118 https://doi.org/10.1038/s41467020-17823-z Djeghloul D, Dimond A, Kramer H, Brown K, Patel B, Wang Y-F, Futschik ME, Whilding C, Monto…
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Postdoctoral Research Associate in flow cytometric preparation and analysis of mitotic chromosomes
type: Vacancy
comment: Pay Scale: STANDARD RESEARCH GRADE 7 Salary (£): £41,997 - £46,913 per annum Location: Department of Biochemistry, South Parks Road, Oxford Contract type: Fixed Term Contract for up to 6 months in the first instance Hours: Full Time (37.5 hours per week) About the role We are seeking to appoint a Postdoctoral Research Associate to join the research group of Prof Amanda Fisher to support an interdisciplinary team working at the intersection between chromosome biology, flow cytometry, microfluidics and molecular/epigenetic analysis. The group’s current work focuses on determining the repertoire and role of proteins that remain bound to mitotic chromosomes through cell division. This uses molecular, genetic and biochemical approaches to disrupt and/or degrade mitotic proteins and evaluate the relevance of such factors in determining chromosome structure and the transmission of cellular identity. To do this we develop new ways of isolating and manipulating native mitotic chromosomes from different organisms using flow cytometry and microfluidic approaches, and then interrogate the function of proteins postulated to ‘bookmark’ the genome through mitosis. We are looking for a dedicated individual to lead the development of technology in this area, supported by existing close collaborations with staff at the MRC LMS. This full-time fixed-term post is funded by the Medical Research Council for up to 6 months in the first instance. The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available. What We Offer Your happiness and wellbeing at work matters to us, so we offer a range of family friendly and financial benefits including: • An excellent contributory pension scheme • 38 days annual leave • A comprehensive range of childcare services • Family leave schemes • Cycle loan scheme • Membership to a variety of social and sports clubs • Discounted bus travel and Season Ticket travel loans T…
application closing date: 2025-04-07T12:00:00+01:00
salary: Research Grade 7: £41,997 - £46,913
comment: **Pay Scale:** STANDARD RESEARCH GRADE 7 **Salary ( £)**: £41,997 - £46,913 per annum **Location:** Department of Biochemistry, South Parks Road, Oxford **Contract type:** Fixed Term Contract for up to 6 months in the first instance **Hours:** Full Time (37.5 hours per week) **About the role** We are seeking to appoint a Postdoctoral Research Associate to join the research group of Prof Amanda Fisher to support an interdisciplinary team working at the intersection between chromosome biology, flow cytometry, microfluidics and molecular/epigenetic analysis. The group’s current work focuses on determining the repertoire and role of proteins that remain bound to mitotic chromosomes through cell division. This uses molecular, genetic and biochemical approaches to disrupt and/or degrade mitotic proteins and evaluate the relevance of such factors in determining chromosome structure and the transmission of cellular identity. To do this we develop new ways of isolating and manipulating native mitotic chromosomes from different organisms using flow cytometry and microfluidic approaches, and then interrogate the function of proteins postulated to ‘bookmark’ the genome through mitosis. We are looking for a dedicated individual to lead the development of technology in this area, supported by existing close collaborations with staff at the MRC LMS. This full-time fixed-term post is funded by the Medical Research Council for up to 6 months in the first instance. The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available. **What We Offer** Your happiness and wellbeing at work matters to us, so we offer a range of family friendly and financial benefits including: • An excellent contributory pension scheme • 38 days annual leave • A comprehensive range of childcare services • Family leave schemes • Cycle loan scheme • Membership to a variety of social and sports clubs • Discounted bus travel and…
application opening date: 2025-03-13T09:00:00+00:00
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