Is Part Of
a un site
We are seeking an ambitious and highly motivated Research Assistant to work in a programme of research that aims to investigate extracellular vesicle biogenesis and biomarkers in Parkinson’s disease. The study will involve the use of iPSC-based models to elucidate molecular mechanisms and biosamples from patient cohorts to validate biomarkers. As such, the post will offer an excellent opportunity for mechanistic and translational research using state-of-the-art models and facilities available at the Kavli Institute for Nanoscience Discovery and Nuffield Department of Clinical Neurosciences at the University of Oxford. The position is ideal for a research assistant that wishes to pursue a DPhil. The post-holder with also benefit from and be exposed to interactions with Industry and work alongside a multidisciplinary team in the Molecular Neurodegeneration Research Group. For details check the lab website at: https://www.ndcn.ox.ac.uk/research/molecular-neurodegeneration-research-group This post is full time and fixed term for 2 years in the first instance. Only applications received before midday 12:00 on Friday 25th April 2025 will be considered. Interviews will be held as soon as possible thereafter.
John Radcliffe Anaesthetic Modular Building
ha sede
Title
street address
locality
country name
Turtle description of Research Assistant In Extracellular Vesicle Biomarkers
Notation3 description of Research Assistant In Extracellular Vesicle Biomarkers
Research Assistant In Extracellular Vesicle Biomarkers
HTML description of Research Assistant In Extracellular Vesicle Biomarkers
Unit price specification
Nuffield Department of Clinical Neurosciences (NDCN), John Radcliffe Hospital, Oxford, OX3 9DU
sotto-Organization di
primary Site
OxPoints
alternative label
telephone
Description of Research Assistant In Extracellular Vesicle Biomarkers
Fax
RDF/XML description of Research Assistant In Extracellular Vesicle Biomarkers
has site
sede principale
Past vacancies at the University of Oxford
postal code
Clinical Neurosciences, Nuffield Department of
valid through (0..1)
notation
site principal
preferred label
es suborganización de
NTriples description of Research Assistant In Extracellular Vesicle Biomarkers
Nuffield Department of Clinical Neurosciences
sous-Organization de
address
Address
Level 6, West Wing, John Radcliffe Hospital, Headley Way
Source
John Radcliffe West Wing and Children's Hospital
We are seeking an ambitious and highly motivated **Research Assistant** to work in a programme of research that aims to investigate extracellular vesicle biogenesis and biomarkers in Parkinson’s disease. The study will involve the use of iPSC-based models to elucidate molecular mechanisms and biosamples from patient cohorts to validate biomarkers. As such, the post will offer an excellent opportunity for mechanistic and translational research using state- of-the-art models and facilities available at the Kavli Institute for Nanoscience Discovery and Nuffield Department of Clinical Neurosciences at the University of Oxford. The position is ideal for a research assistant that wishes to pursue a DPhil. The post-holder with also benefit from and be exposed to interactions with Industry and work alongside a multidisciplinary team in the Molecular Neurodegeneration Research Group. For details check the lab website at: https://www.ndcn.ox.ac.uk/research/molecular- neurodegeneration-research-group **This post is full time and fixed term for 2 years in the first instance.** **Only applications received before midday 12:00 on Friday 25th April 2025 will be considered. ** **Interviews will be held as soon as possible thereafter.**
Subject
subOrganization of
has exact match
tiene sede en
License
West Wing, Level 6, John Radcliffe Hospital, Oxford, OX3 9DU Web: www.ndcn.ox.ac.uk | Tel: +44(0)1865 234702 | Email: recruitment@ndcn.ox.ac.uk Job title Research Assistant in Extracellular Vesicle Biomarkers Division Medical Sciences Division Department Nuffield Department of Clinical Neurosciences (NDCN) Location John Radcliffe Hospital, Oxford, OX3 9DU Grade and salary Research Grade 6: £34,982 - £40,855 per annum Hours Full time Contract type Fixed-term for 2 years in the first instance with possibility of extension Reporting to Prof George Tofaris Vacancy reference 179036 Research topic Molecular mechanisms in Parkinson’s disease pathogenesis Principal Investigator / supervisor Prof George Tofaris MRC Senior Clinical Fellow Professor and Consultant in Neurology, University of Oxford Project team https://www.ndcn.ox.ac.uk/research/molecularneurodegeneration-research-group Project web site https://www.ndcn.ox.ac.uk/team/george-tofaris Funding partner The funds supporting this research project are provided by MJFF Recent publications Yan et al., Cell Reports Med (2025); Yan et al., JAMA Neurol. 81, 59-68 (2024); Tanudjojo et al., Nature Commun. 2021, 12(1):3817; Alexopoulou et al., Proc. Natl. Acad. Sci USA 2016, 113(32):E4688-97; Jiang et al., J Neurol Neurosurg. Psychiatry 2020, 91(7): 720-729, The role We are seeking an ambitious and highly motivated research assistant to work in a programme of research that aims to investigate extracellular vesicle biogenesis and biomarkers in Parkinson’s disease. The study will involve the use of iPSC-based models to elucidate molecular mechanisms and biosamples from patient cohorts to validate biomarkers. As such, the post will offer an excellent opportunity for mechanistic and translational research using state-of-the-art models and facilities available at the Kavli Institute for Nanoscience Discovery and Nuffield Department of Clinical Neurosciences at the University of Oxford. The position is ideal for a research assistant that wishes to pursue a DPhil. The post-holder with also benefit from and be exposed to interactions with Industry and work alongside a multidisciplinary team in the Molecular Neurodegeneration Research Group. For details check the lab website at: https://www.ndcn.ox.ac.uk/research/molecular-neurodegeneration-research-group You will have previous research experience, an aptitude for mechanistic studies and the ability to work collaboratively within a team. Responsibilities • • Manage own research with guidance from senior colleagues Use established lab protocols to isolate and characterise extracellular vesicles, analyse scientific data to test new hypotheses • Perform experiments involving advanced microscopy techniques • Present research and contribute data for publication. • Undertake other duties in the laboratory from time to time that are commensurate with the grade and responsibilities of this post. Selection criteria Essential selection criteria • • • • • • • Drive and enthusiasm to perform research and work as a member of a team Excellent written and communication skills BSc or equivalent with previous relevant research experience Working towards a doctorate in a specialist discipline Proven track record in cell culture and imaging Proven track record in molecular biology including cloning Working knowledge of statistical programs relevant to basic research Desirable selection criteria • Knowledge of protein aggregation • Previous experience in models of Neurodegeneration 2 Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. If you have previously worked for the University we will also verify key information such as your dates of employment and reason for leaving your previous role with the department/unit where you worked. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • Lone Working • Working with blood, human products and human tissues • Work with any substance which has any of the following pictograms on their MSDS: About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities. Income from external research contracts in 2016/17 exceeded £564m and we rank first in the UK for university spinouts, with more than 130 companies created to date. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. 3 For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognized centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information visit: www.medsci.ox.ac.uk The Nuffield Department of Clinical Neurosciences The Nuffield Department of Clinical Neurosciences (NDCN), led by Prof Kevin Talbot, has over 400 staff and 150 postgraduate students. NDCN has an established research and teaching portfolio with a national and international reputation for excellence. NDCN is based in high quality research and clinical facilities in the West Wing of the John Radcliffe Hospital, alongside the Department's world-class Oxford Centre for Functional MRI of the Brain (FMRIB), the Weatherall Institute of Molecular Medicine (which houses 3 of our research groups) and provides the ideal facilities to translate research from bench to bedside. In keeping with the award of NIHR Comprehensive Biomedical Research Centre status, to a partnership between Oxford University and the Oxford Radcliffe Hospitals NHS Trust, we have developed a highly integrated and interdisciplinary environment in which research, teaching, clinical training and clinical care interact. This enables us to establish new approaches to the understanding, diagnosis and treatment of brain diseases. To this end the Department fosters collaborations worldwide and warmly welcomes visiting scientists, clinical fellows and students. The Department comprises five sections. For more information visit: www.ndcn.ox.ac.uk Nuffield Division of Anaesthesia NDA is led by Professor Andrew Farmery. The NDA is committed to the development and maintenance of internationally competitive research programmes in pain and consciousness; respiration and hypoxia; adult and neuro-intensive care; simulation and human factors training. For more information visit www.nda.ox.ac.uk Division of Clinical Neurology DCN is led by Professor David Bennett. DCN is committed to the development of research programs that improve understanding of the nervous system in health and disease. For more information visit www.dcn.ox.ac.uk Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB is led by Professor Heidi Johansen-Berg. FMRIB is an internally recognised human neuroimaging centre housing both 3T and 7T scanners. The Centre has strong programmes of research in MR physics, image analysis and the applications of neuroscience in health and disease. For more information visit www.fmrib.ox.ac.uk 4 Nuffield Laboratory of Ophthalmology NLO is led by Professor Russell Foster, who leads the Sleep & Circadian Neuroscience Institute. NLO pursues scientific and clinical research into a range of areas related to vision, the eye and circadian neuroscience. For more information visit www.nlo.ox.ac.uk Centre for the Prevention of Stroke & Dementia CPSD is led by Professor Peter Rothwell. The centre carries out research that increases understanding of the causes of cerebrovascular disease. Its aims are to improve prevention of stroke and dementia by earlier diagnosis, more reliable prognostication, and more effective use of existing preventive treatments in routine clinical practice. For more information visit https://www.ndcn.ox.ac.uk/divisions/cpsd Working at NDCN NDCN actively promotes a healthy work life balance amongst employees through a number of family friendly policies. See http://www.admin.ox.ac.uk/personnel/staffinfo/benefits/ for further information. The University of Oxford is a member of the Athena SWAN Charter and holds an institutional Bronze Athena SWAN award. The Department of Clinical Neurosciences holds a departmental Silver Athena award in recognition of its efforts to introduce organisational and cultural practices that promote advancement of gender equality: representation, progression and success for all. How to apply Before submitting an application, you may find it helpful to read the ‘Tips on applying for a job at the University of Oxford’ document, at www.ox.ac.uk/about/jobs/supportandtechnical/. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the on-screen instructions to register as a new user or log-in if you have applied previously. Please provide details of two referees and indicate whether we can contact them now. You will also be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday on the closing date stated in the online advertisement. 5 Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). Should you experience any difficulties using the online application system, please email recruitment.support@admin.ox.ac.uk. Further help and support is available from www.ox.ac.uk/about_the_university/jobs/support/. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our e-recruitment system to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: www.admin.ox.ac.uk/councilsec/compliance/gdpr/privacynotices/job/. The University’s Policy on Data Protection is available at: www.admin.ox.ac.uk/councilsec/compliance/gdpr/universitypolicyondataprotection/. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for all academic posts and some academic-related posts. The University has adopted an EJRA of 30 September before the 69th birthday for all academic and academic-related staff in posts at grade 8 and above. The justification for this is explained at: www.admin.ox.ac.uk/personnel/end/retirement/acrelretire8+/. For existing employees, any employment beyond the retirement age is subject to approval through the procedures: www.admin.ox.ac.uk/personnel/end/retirement/acrelretire8+/. There is no normal or fixed age at which staff in posts at grades 1–7 have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of Opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 6 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See www.admin.ox.ac.uk/personnel/staffinfo/benefits. University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and www.sport.ox.ac.uk/oxford-university-sports-facilities. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See www.welcome.ox.ac.uk. There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See www.admin.ox.ac.uk/personnel/permits/reimburse&loanscheme/. Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to My Family Care, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See www.admin.ox.ac.uk/personnel/staffinfo/benefits/family/mfc/. Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see www.admin.ox.ac.uk/childcare/. Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see www.admin.ox.ac.uk/eop/disab/staff. Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at www.admin.ox.ac.uk/eop/inpractice/networks/. The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. 7
Research Grade 6: £34,982 - £40,855 per annum
email
Format
Voice
extended address
tiene sede principal en