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We are seeking a motivated and experienced Postdoctoral Research Assistant to join a flourishing program of research led by Dr. Rachel Tanner, studying tuberculosis (TB) with a focus on novel TB drug development and evaluation. The successful applicant will be required to work primarily on in vitro and ex vivo screening of drug candidates. The work will be conducted at the Peter Medawar Building for Pathogen Research and the new Life and Mind Building in central Oxford.

The role will include microbiological techniques, assay development and optimisation, performing immunological evaluations, and analysing, interpreting and presenting data. Attention to detail is essential. The postholder will have excellent organisational and laboratory management skills, and will be a team-player able to support other members of the group including junior staff, graduate and undergraduate project students as required. Some travel to collaborator institutes (particularly Birkbeck, University of London) will be required for training and tech-transfer.

 

The University of Oxford is committed to equality and valuing diversity. All applicants will be judged on merit, according to the selection criteria.

 

This post is full-time and available from 1st July 2025 for a fixed term till 29th February 2028.

 

The closing date for applications is 12.00 noon on Wednesday 7th May 2025; interviews are likely to be scheduled for June 2025.

 
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"""Job description Post Postdoctoral Research Assistant in Microbiology and Immunology Department Department of Biology Division Mathematical, Physical and Life Sciences Division (MPLS) Location Peter Medawar the Building 3 S Parks Rd, Oxford OX1 3SY, you may be relocated to the new Life and Mind Building when it is ready Grade and salary Researcher Grade 7.1 – 7.3: £38,674 - £40,855 per annum Hours Full time Contract type Fixed-term contract till 29TH Feb 2028 Reporting to Prof. Rachel Tanner Application deadline 12 noon Wednesday 7th May Vacancy reference 179206 Recruitment contacts HR: recruitment@biology.ox.ac.uk Research topic Microbiology, immunology, tuberculosis, drug development Principal Investigator / supervisor Prof. Rachel Tanner Project team Project web site Recent publications IOI Grand Challenge Consortium (Rachel Tanner, Alistair Farley, Helen McShane, Martin Maiden) https://www.ineosoxford.ox.ac.uk/ https://scholar.google.com/citations?user=2LhJYZAAAAAJ&hl=en&oi= ao The role The work of the Tanner Lab is concerned with tuberculosis (TB) in humans and cattle, with a focus on drug and vaccine design and evaluation. In particular, we are interested in immune mechanisms/correlates of protection, characterising the specific and non-specific antibody responses to TB vaccines, and novel antigen discovery. We currently have projects exploring humoral correlates of protection in human TB challenge models, the effect of climate change on environmental mycobacteria, genetic variation in circulating M. bovis strains, and the development of functional models for high-throughput vaccine screening that align with the principles of the 3Rs (replacement, reduction and refinement) for the use of animals in scientific procedures. The post-holder will take a leading role in laboratory research for a new Ineos Oxford Institute (IOI)-funded project establishing a pipeline for novel TB drug development and will provide guidance and support to less experienced members of the group. You will be required to work under sterile conditions with mycobacterial strains (including drugsusceptible and drug-resistant Mycobacterium tuberculosis), as well as cell, tissue and immunology samples in collaboration with a PI, Research Assistants, research students and the wider consortium, and to provide technical and administrative support. This includes planning and performing experiments, assay development and optimisation to a high standard as well as day-to-day laboratory duties. You will be extremely organised with proven experience in a laboratory environment including at Containment Level 3. You will have good interpersonal skills and be able to interact productively and accurately with other team members and collaborators. You will be based at the Peter Medawar Building for Pathogen Research and the new Life and Mind Building, South Parks Road, Oxford. Responsibilities  Work independently to plan and perform microbiological and immunological assays using preclinical and clinical samples; develop and optimise assay conditions; use specialist scientific equipment in a laboratory environment, and maintain accurate records of all experimental work. Conduct laboratory work to a high standard following established standard operating procedures (SOPs), protocols, risk assessments, and in compliance with Good Laboratory Practice, the Human Tissue Authority (HTA) and Medicines and Healthcare products Regulatory Agency (MHRA) regulations where required; ensure that work in the laboratory is conducted safely using appropriate safety procedures, PPE, and in the correct designated areas.  Liaise closely with internal and external collaborators, which will include visits to their laboratories (particularly Birkbeck, University of London) for tech-transfer and training.  Analyse and interpret data and present results to the PI, group, wider consortium and department; represent the group at external meetings/seminars; write scientific manuscripts, new experimental protocols, risk assessments, and other documentation.  Manage own academic research and administrative activities. This involves small scale project management to co-ordinate multiple aspects of work to meet deadlines.  Contribute ideas for new research directions and projects, including developing ideas for generating research income and presenting proposals to senior researchers.  Provide training to and oversight of junior members of staff and co-supervise students working in the laboratory, providing technical and administrative assistance to all members of the group; act as a source of information and advice to other members of the group on scientific protocols, experimental planning and techniques, data analysis and interpretation.  Oversee the daily housekeeping of the laboratory area and support junior researchers in performing tasks including reagent ordering and preparation, stock control of laboratory consumables, shipping and receipt of samples and reagents, biobanking, routine cleaning of equipment, and maintaining laboratory documentation, sample inventories and reagent information at the required level.  Be flexible in working hours, with a requirement to sometimes work later hours on weekdays and on weekends if experiments require; undertake other duties as may be required from time to time that are commensurate with the grade and responsibilities of this post.  Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Identify personal development needs and use all reasonable opportunities to maintain and develop personal and professional knowledge and skills.  Accord due regard to the University Equal Opportunities, IT Security and Data Protection policies; and to the Funder requirements for each project. Embed the principles of mutual respect, equality, diversity, inclusivity and sustainability in all aspects of your work; undertake associated training as and when asked to do so.  Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year.  Teach or undertake ad-hoc teaching (this may include lecturing, demonstrating, small group teaching, tutoring of undergraduates and graduate students and supervision of projects). Selection criteria Essential selection criteria  Hold, or be close to completion of, a relevant PhD/DPhil  Possess sufficient specialist knowledge in the field of microbiology and immunology, including experience in culturing mycobacteria, sterile cell culture and performing routine immunological assays  Experience of working in Containment Level 2 and 3 laboratories  Ability to effectively manage a research project, organise own work and work independently with minimum supervision  Experience of training and supervising other staff/students in the laboratory  Experience of contributing to publications and presentations with excellent communication skills, and contributing ideas for new research projects and research income generation Desirable selection criteria  Experience in drug development and drug screening assays such as MIC, bactericidal assays, intracellular activity  Experience in handling of Mycobacterium tuberculosis and performing functional ex vivo assays  Experience of working collaboratively including with external research institutes and groups Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. If you have previously worked for the University we will also verify key information such as your dates of employment and reason for leaving your previous role with the department/unit where you worked. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows:  Night working (11pm-6am)  Lone Working  Driving on University business  Working with infectious pathogens (hazard group 2/3) - Hazard Group 3 pathogens  Working with blood, human products and human tissues  Work with allergens, Eg laboratory animals, pollen, dust, fish or insects etc.  Work with any substance which has any of the following pictograms on their MSDS:  Travel outside of Europe or North America on University Business About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. The Department of Biology You will be joining the Department of Biology at an exciting time. The Department established from August 2022 as a result of a merger between the Departments of Zoology and Plant Sciences, and is preparing to move into the new state-of-the-art Life and Mind Building in 2025. The Department of Biology is recognised internationally for its research in a wide range of fields spanning all levels from molecules to ecosystems, and tackling global challenges through fundamental bioscience research. Over time, the research interests of the Department has been focused on five primary themes: Behaviour & Biomechanics; Ecology & Conservation; Evolutionary Biology; Microbiology & Infectious Disease; and Molecular Plant Biology. Research is conducted in all spheres from laboratory and in silico analysis to theoretical and field-based research. At all times we seek to reinforce the connections between research and our education offering, at both graduate and undergraduate level. The Department teaches a four-year undergraduate degree MBiol course in Biology, with fourth-year students undertaking a Masters-level research project. It also supports a variety of graduate placements and hosts the University’s DPhil in Biology. External research income to the Department is derived from over 50 different funding agencies, with the principal current funders being the European Research Council, the Royal Society, the Wellcome Trust, BBSRC and NERC. The Department has a significant record in integrating broader societal impacts of its research, including the provision of policy to government at the highest level, as well as supporting the commercialisation of research through spin-out companies and licensing arrangements that have generated hundreds of millions of pounds’ worth of innovation. The Department is located in the University’s Science Area at two sites and will move into the new £200m Life and Mind Building in 2024 that will include extensive laboratory provision with controlled environment rooms, glasshouses and an imaging suite. The Department also benefits from extensive facilities at the John Krebs Field Station at Wytham, with Wytham Woods nearby, as well as partnerships with organisations in the area such as the Oxford Botanic Gardens and Oxford Natural History Museum. For more information please visit: https://www.biology.ox.ac.uk The Department of Biology holds a bronze Athena Swan award to recognise advancement of gender equality: representation, progression and success for all. About the Mathematical, Physical, and Life Sciences (MPLS) Division The Mathematical, Physical, and Life Sciences (MPLS) Division is one of the four academic divisions of the University, alongside the Humanities, Social Sciences and Medical Sciences Divisions. It is led by an academic Head of Division (Professor Jim Naismith) and an administrative Divisional Registrar (Dr Tracy Gale) and comprises nine of the University’s academic departments – Biology, Chemistry, Computer Science, Earth Sciences, Engineering Science, Materials, the Mathematical Institute, Physics, and Statistics – as well as Begbroke Science Park, the multidisciplinary Ineos Oxford Institute for Antimicrobial Research and an interdisciplinary Doctoral Training Centre. MPLS is proud to be home to some of the most creative and innovative scientific thinkers and leaders in academia, whose interdisciplinary research is tackling major societal and technological challenges, from new energy solutions or improved cancer treatments to understanding climate change processes and helping to preserve biodiversity, tackling antimicrobial resistance, advancing AI and quantum technologies and space exploration, and much more. The quality and impact of our work have been recognised by successive rounds of the national Research Excellence Framework and Teaching Excellence and Student Outcomes Framework exercises, and our departments frequently top the major higher education league tables. We teach around 7,300 students (including around 3,400 graduate students) and are playing a key part in training the next generation of leading scientists. Divisional activity is co-ordinated and represented by the MPLS Divisional Office based at 9 Parks Road, in the heart of Oxford’s Science Area. The Divisional Office, which is led by the Divisional Registrar, has around 55 dedicated members of staff, as well as a number of colleagues who are embedded in divisional teams but based in central University services (e.g. in Finance, HR and Development). To find out more, please visit: www.mpls.ox.ac.uk. How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that: - as part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs Non-technical questions about this job should be addressed to the recruiting department directly at Recruitment@Biology.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82 of 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, flexible working options, travel discounts including salary sacrifice schemes for bicycles and electric cars and other discounts. Staff can access a huge range of personal and professional development opportunities. See https://hr.admin.ox.ac.uk/staff-benefits Employee Assistance Programme As part of our wellbeing offering staff get free access to Health Assured, a confidential employee assistance programme, available 24/7 for 365 days a year. Find out more https://staff.admin.ox.ac.uk/health-assured-eap University Club and sports facilities Membership of the University Club is free for University staff. It offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ Reimbursement Policy: https://staffimmigration.admin.ox.ac.uk/reimbursement-policy There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependants. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits We are a family-friendly employer with one of the most generous family leave schemes in the Higher Education sector (see https://hr.web.ox.ac.uk/family-leave). Our Childcare Services team provides guidance and support on childcare provision, and offers a range of high-quality childcare options at affordable prices for staff. In addition to 5 University nurseries, we partner with a number of local providers to offer in excess of 450 full time nursery places to our staff. Eligible parents are able to pay for childcare through salary sacrifice, further reducing costs. See https://childcare.admin.ox.ac.uk/. Supporting disability and health-related issues (inc menopause) We are committed to supporting members of staff with disabilities or long-term health conditions, including those experiencing negative effects of menopause. Information about the University’s Staff Disability Advisor, is at https://edu.admin.ox.ac.uk/disability-support. For information about how we support those going through menopause see https://hr.admin.ox.ac.uk/menopause-guidance Staff networks The University has a number of staff networks including for research staff, BME staff, LGBT+ staff, disabled staff network and those going through menopause. 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