Description of Postdoctoral Research Associate
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The Jenner Institute
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occupies: Wellcome Trust Centre Clinical Vaccinology and Tropical Medicine
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has site: Wellcome Trust Centre Clinical Vaccinology and Tropical Medicine
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Postdoctoral Research Associate
subject: research
organization part: The Jenner Institute
type: Vacancy
application closing date: 2025-04-29T12:00:00+01:00
application opening date: 2025-04-15T09:00:00+01:00
internal applications only: false
further particulars: 179212 Postdoctoral Research Associate (Rinaldi Lab) Job Description
contact: Carlo Rinaldi
comment: About the role A position is available for a highly motivated Postdoctoral Research Associate to join the research group led by Prof Carlo Rinaldi at the University of Oxford. The group explores genetic causes of neurological disorders and aim to develop therapies for such conditions with a high complementary approach, ranging from stem cell modelling to functional genomic. Enhancers play a pivotal role in governing gene expression, and their disruption is increasingly recognized as a key driver of diseases. This is an exciting opportunity for a postdoctoral scientist to help lead a project focusing on interrogating enhancer function in the context of rare neurological diseases, with the goal to precisely modulate enhancer activity to fine-tune gene expression patterns and offer treatment opportunities for these diseases. The project will use a wide variety of data processing, data analysis, and statistical techniques to functional genomic data (ChIP-seq, RNA-seq, ATAC-seq, co-accessibility). Analysis will be performed on collaborative cloud computing environments using the extensive computing infrastructure developed by the Sanders Lab. You will be involved with all aspects of the data analysis including design, conduct, and dissemination. The post holder will work at the newly built Institute of Developmental and Regenerative Medicine (IDRM) at the Old Road Campus of University of Oxford in the laboratories of Prof Carlo Rinaldi. You will be well supported by the existing joint team, currently consisting of postdocs, bioinformaticians, PhD candidates, and research assistants. The post holder will be able to receive training in collaborating labs in order to benefit from interaction with researchers in diverse environments. You will be encouraged to attend training and research skill courses provided by the University of Oxford. There will be opportunities for contributing to and leading grant applications if appropriate, as well as being encouraged to submit work …
formal organization: University of Oxford
notation: 179212
comment: **About the role** A position is available for a highly motivated Postdoctoral Research Associate to join the research group led by Prof Carlo Rinaldi at the University of Oxford. The group explores genetic causes of neurological disorders and aim to develop therapies for such conditions with a high complementary approach, ranging from stem cell modelling to functional genomic. Enhancers play a pivotal role in governing gene expression, and their disruption is increasingly recognized as a key driver of diseases. This is an exciting opportunity for a postdoctoral scientist to help lead a project focusing on interrogating enhancer function in the context of rare neurological diseases, with the goal to precisely modulate enhancer activity to fine-tune gene expression patterns and offer treatment opportunities for these diseases. The project will use a wide variety of data processing, data analysis, and statistical techniques to functional genomic data (ChIP-seq, RNA-seq, ATAC-seq, co-accessibility). Analysis will be performed on collaborative cloud computing environments using the extensive computing infrastructure developed by the Sanders Lab. You will be involved with all aspects of the data analysis including design, conduct, and dissemination. The post holder will work at the newly built Institute of Developmental and Regenerative Medicine (IDRM) at the Old Road Campus of University of Oxford in the laboratories of Prof Carlo Rinaldi. You will be well supported by the existing joint team, currently consisting of postdocs, bioinformaticians, PhD candidates, and research assistants. The post holder will be able to receive training in collaborating labs in order to benefit from interaction with researchers in diverse environments. You will be encouraged to attend training and research skill courses provided by the University of Oxford. There will be opportunities for contributing to and leading grant applications if appropriate, as well as being encouraged to submit w…
spatial: Department of Paediatrics, Rinaldi Lab, Institute of Developmental & Regenerative Medicine IDRM, Old Road Campus, Oxford
based near: Old Road Campus Research Building
salary: Research Grade 8: 48,235 - 57,255 with a discretionary range to £64,228 per annum (pro-rata)

University of Oxford
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Henry Wellcome Building of Cellular and Molecular Physiology
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Nuffield Department of Clinical Medicine
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Research Grade 8: 48,235 - 57,255 with a discretionary range to £64,228 per annum (pro-rata)
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Carlo Rinaldi
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179212 Postdoctoral Research Associate (Rinaldi Lab) Job Description
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value: _________________________________________________________________________ Job description and selection criteria Job title Postdoctoral Research Associate Division Medical Sciences Department Paediatrics Location Institute of Developmental & Regenerative Medicine (IDRM) University of Oxford Grade and salary Research Grade 8: £48,235 - £57,255 per annum (with a discretionary range to £64,228 per annum) Hours Full-time Contract type Fixed-term (12 months) or until 30 September 2026, whichever is sooner Reporting to Prof Carlo Rinaldi, Professor of Molecular and Translational Neuroscience Vacancy reference 179212 Additional information Research topic Applications are to be made online, please see the advert for the closing date. This role meets the criteria for a UK Skilled Worker visa Therapy development for rare neurological diseases Principal Investigator Prof Carlo Rinaldi / supervisor Project team Rinaldi Lab Project web site https://www.idrm.ox.ac.uk/research/neurology Funding partner The funds supporting this research project are provided by a gift agreement The role Reporting to Dr. Carlo Rinaldi, who is based at the IDRM, the post holder will be a member of the Rinaldi lab, with responsibility for carrying out research to understand the genetics and neurobiology underlying neurological and neurodevelopmental disorders, with the ultimate goal to develop treatments for these conditions. The post holder will also work as a member of a multidisciplinary team and provide guidance to other members of the research group, including other postdocs, research assistants, technicians, and PhD and project students. The Rinaldi lab (https://www.rinaldi-lab.com/) has access to unique disease modelling systems (e.g. stem cells-derived neurons and organoids on a chip) and numerous datasets of varying scales on university computer clusters and cloud-based services (AWS and Google). This post offers a uniquely rich opportunity to manage data assets and deploy data processing and…
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