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Research Assistant
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comment: We have an exciting opportunity for a Research Assistant to join the research group headed by Professor Geraldine Gillespie and Emeritus Professor Andrew McMichael in the Nuffield Department of Medicine, Centre for Immuno-Oncology, which carries out basic and translational immunological research on the non- classical major histocompatibility molecule (MHC), HLA-E. You will be responsible for establishing in vitro co-culture systems of primary CD8+ T cells with 3D cultures of HPV-containing keratinocytes and fibroblasts (e.g., spheroids or organotypic raft cultures) for testing engineered T-cell therapies in pre-clinical proof-of-concept studies. You will perform lab-based experimental work of a high standard, to carry our techniques carefully and accurately and keeping good records of all work performed. This work also includes contributing to presentation of research reports and publications and smooth running of the laboratory ensuring that work in the Department is conducted safely and legally. It is essential that you hold a BSc degree in a relevant biomedical science area together alongside experience with mammalian tissue culture and, ideally, with establishing 3D tissue culture systems (e.g., spheroids or organoids). You will also have experience in growing primary CD8+ T cells and T cell lines. You will also have excellent communication skills and will be able to work independently as well as part of a multidisciplinary team. Having experience of working with murine tissue samples is desirable. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract until 30 November 2026 and …
application opening date: 2025-05-14T09:00:00+01:00
formal organization: University of Oxford
organization part: Department of Oncology
salary: Research Grade 6: Research Grade 6: £34,982 - £40,855 with a discretionary range to £45,628 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata
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spatial: Oxford Centre for Immuno-Oncology, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ
comment: We have an exciting opportunity for a Research Assistant to join the research group headed by Professor Geraldine Gillespie and Emeritus Professor Andrew McMichael in the Nuffield Department of Medicine, Centre for Immuno-Oncology, which carries out basic and translational immunological research on the non-classical major histocompatibility molecule (MHC), HLA-E. You will be responsible for establishing in vitro co-culture systems of primary CD8+ T cells with 3D cultures of HPV-containing keratinocytes and fibroblasts (e.g., spheroids or organotypic raft cultures) for testing engineered T-cell therapies in pre-clinical proof-of-concept studies. You will perform lab-based experimental work of a high standard, to carry our techniques carefully and accurately and keeping good records of all work performed. This work also includes contributing to presentation of research reports and publications and smooth running of the laboratory ensuring that work in the Department is conducted safely and legally. It is essential that you hold a BSc degree in a relevant biomedical science area together alongside experience with mammalian tissue culture and, ideally, with establishing 3D tissue culture systems (e.g., spheroids or organoids). You will also have experience in growing primary CD8+ T cells and T cell lines. You will also have excellent communication skills and will be able to work independently as well as part of a multidisciplinary team. Having experience of working with murine tissue samples is desirable. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract until 30 November 2026 and i…

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value: Job title Research Assistant Division Medical Sciences Department Nuffield Department of Medicine Location Oxford Centre for Immuno-Oncology, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ Grade and salary Research Grade 6: £34,982 - £40,855 with a discretionary range to £45,628 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata). Hours Full time Contract type Fixed-term contract until 30 November 2026 Funding is provided by Bill and Melinda Gates Foundation Reporting to Geraldine Gillespie, PI/Group Head Vacancy reference 179347 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship. About us    What we offer https://hr.admin.ox.ac.uk/staff-benefits  An excellent contributory pension scheme  38 days annual leave  A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata)  A comprehensive range of childcare services  Family leave schemes  Cycle loan scheme  Discounted bus travel and Season Ticket travel loans  Membership to a variety of social and sports clubs  A welcoming and diverse community Research topic HLA-E-based therapeutic vaccines that target HPV Principal Investigator / supervisor Geraldine Gillespie Project team https://www.immonc.ox.ac.uk University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - https://www.immonc.ox.ac.uk/ Project web site https://www.ndm.ox.ac.uk/team/geraldine-gillespie Funding partner The funds supporting this research project are provided by the Bill and Melinda Gates Foundation Recent publications HLA-E: Immune Receptor Functional Mechanisms Revealed by Structural Studies. Gillespie GM. et al, (2025), Immunological reviews, 329 The role We are seeking to appoint a Research Assistant to join the research group headed by Professor Geraldine Gillespie and Emeritus Professor Andrew…
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