Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, Windmill Road, Oxford, OX3 7LD
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We have an exciting opportunity for a Project Administrator to join the Oxford Trauma group at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, to be based at the Kadoorie Critical Care Centre, John Radcliffe Hospital, Oxford. The Oxford Trauma and Emergency Care group has a successful research portfolio in the UK and internationally. You will liaise with a large range of professionals at collaborating institutions, including partners based in Low and Middle Income Country (LMIC) settings As a Project Administrator, you will carry out day-to-day administrative coordination of project(s) with minimum supervision, reporting problems immediately, and providing updates to the Trial Manager. You will provide administrative support for meetings, including management of diaries/electronic calendars, the preparation and distribution of agendas and taking, transcription and distribution of minutes as well as follow-up of action points arising from meetings. You will be responsible for monitoring of your own project and related junior staff to ensure quality assurance compliance and you will provide administrative support to the Trial Manager in the development of case report forms and documents. You must be educated to A-Level standard (or possess equivalent administrative qualifications/experience). You will have excellent IT literacy, including a strong working knowledge of Word and Excel, with the ability to create and use spreadsheet applications. Evidence of following and working to detailed written instructions associated with quality control or compliance, and ability to maintain clear and accurate records and demonstrable knowledge of data management, research quality management and monitoring activities are essential. Understanding of clinical governance and its implications and importance for research as well as experience of research in Low and Middle Income Countries would be desirable. This is a full time (part time, at minimum of 70% FTE will be considered) fixed-term appointment for 2 years in the first instance. The closing date for this position is 12 noon on 8 May 2024. You will be required to upload a supporting statement as part of your online application.
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
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We are seeking to appoint a highly qualified and dedicated Programme Manager for Functional Genomics Cluster, this is a new and exciting role for the UK Research and Innovation Musculoskeletal Functional Genomics Initiative Cluster (MSK Cluster) based at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), Botnar Research Centre, Oxford. The MSK Cluster is led by Professor Dominic Furniss, and the funding provides support for researchers spanning the breadth of a translational medicine pipeline from basic genetics, bioinformatics and AI, through functional genomic readouts and tissue imaging, to human tissue models, organoids, and bioreactors. You will be part of an interdisciplinary team of scientists and clinician researchers, spread across both Oxford and Manchester Universities, with international collaborators in Europe and the USA, as well as Industrial partners. In addition, it is anticipated that there will be close collaboration with the other funded clusters in Edinburgh and London. As a Programme Manager for Functional Genomics Cluster, you will be an integral part of our team and you will manage all non-academic administration functions for the Centre including, financial review and communications. You will provide updates and report issues or concerns to the Principal Investigator and/or the study team. Supervise the strategic dissemination of information for projects, with the support of the Department’s Communications team where appropriate; and maintain the digital profile of the Cluster through the website/social media. You will be responsible for organisation of meetings and events, submission of budget requests and reports to funders as well as being involved in and supporting any relevant public engagement activities on our group’s agenda. You will be educated to a degree level or have equivalent, relevant professional experience. Proven management, resource planning and project management experience with ability to work independently and problem solve, knowledge of UK clinical research structures, regulatory and ethical systems, and experience of working to a high standard of Good Clinical Practice and proven experience organising internal and external events are essential. Experience working in higher education and knowledge or interest in research subject area of the department are desirable. This is a part-time (50% FTE) fixed-term until 30/04/2028 appointment. The closing date for this position is 12 noon on 03/05/2024. You will be required to upload a CV and supporting statement as part of your online application.
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We have an exciting opportunity for a Research Assistant in Epidemiology and Health Data Sciences to join the Pharmaco- and Device epidemiology research group led by Professor Daniel Prieto-Alhambra at the Botnar Research Centre, NDORMS, University of Oxford. The NDORMS Pharmaco- and Device epidemiology research group is involved in a number of national and international studies exploring the conditions of use (adherence, compliance, off and on-label use) of a number of licensed drugs, devices, and vaccines for the prevention and treatment of human disease in 'real world' (routine practice) conditions. As a Research Assistant in Epidemiology and Health Data Sciences you will support the analysis and management for studies on our portfolio using routinely collected data mapped to the OMOP Common Data Model. You will contribute to the development of study documentation for our studies, you will use R packages to run a number of pre-specified analyses and you will conduct and support research activities based on your relevant expertise area. You will contribute to publications, scientific reports and journal articles as well as the presentation of data/papers at conferences and other scientific meetings. You will hold a relevant post-graduate degree in Epidemiology or a related field together with experience in biostatistics and/or health data sciences. Experience in programming statistical analyses, preferably in R and experience in writing scientific documents, e.g. study reports, manuscripts are essential. As are ability to work within multi-disciplinary teams and independently, good communication skills and excellent team working skills. Experience in the analysis or interpretation of OMOP-mapped data, experience in working with electronic medical records/routinely collected/real world data and experience in generating phenotypes are desirable. This is a full-time fixed-term appointment for 2 years. The closing date for this position is 12 noon on 10 May 2024. You will be required to upload a CV and supporting statement as part of your online application.
Programme Manager for Functional Genomics Cluster (part-time)
Standard Grade 6: £32,332- £38,205 p.a. A lower grade offer may be made(Grade 5: £28,759- £33,966 p.a.)with commensurate reduction in responsibilities(and a change in job title to Project Administrator) if a suitable candidate cannot be found to fill the Grade 6 position.
Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Department of (NDORMS)
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The Kennedy Institute at the University of Oxford has an exciting opening for an experienced bioinformatician to join the group of Associate Professor Stephen Sansom (https://sansomlab.org). In this core-funded role you will lead the development of pipelines and tools for the analysis of data from cutting- edge single cell and spatial genomics platforms such as the 10x Chromium and Nanostring CosMx. You will have the opportunity to work with students and postdocs from the Kennedy’s world-leading research groups both to provide bioinformatics training and to make contributions to publications in high impact journals. Researchers at the KIR are using cutting-edge approaches to investigate the immune system and the cellular causes of diseases such as atheroschlerosis, inflammatory bowel disease and arthritis (https://www.kennedy.ox.ac.uk/research/research-groups). You should have an established track record of code development and contributions to publications or submitted manuscripts in peer-reviewed journals that demonstrates your bioinformatics expertise. A PhD/DPhil (or near completion) in a discipline of direct relevant to bioinformatics and genomic research is essential. In this role, you will undertake code development, provide bioinformatics training and perform scientific research developing and acquiring relevant skills as necessary. You will share code with the bioinformatics community, publishing tools and results in peer-reviewed journals. A good understanding of single-cell/spatial genomics data analysis is essential. The successful applicant will be based at the Kennedy Institute of Rheumatology within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences. The closing date for this position is **12 noon on Friday 3 May 2024**. Please read the accompanying job description carefully and ensure that you address each selection criteria in a supporting statement which must be uploaded together with your CV when applying online. For further information please contact Associate Professor Stephen Sansom: stephen.sansom@kennedy.ox.ac.uk or Prof Irina Udalova: irina.udalova@kennedy.ox.ac.uk. This core-funded post will be initially appointed as a fixed-term, full time position until 31/07/2026.
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NDORMS, Nuffield Orthopaedic Centre, Windmill Road, Oxford, OX3 7HE
Job Description _________________________________________________________________________ Summary Job title Project Administrator Division Medical Sciences Division Department Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Location Botnar Research Centre, Windmill Road, Oxford, OX3 7LD Grade and salary Grade 5: £28,759-£33,966 per annum Hours Full time (part time, at minimum of 70% FTE will be considered) Contract type Fixed-term (2 years) Reporting to Clinical Trial Manager Vacancy reference 172438 The role The purpose of this role is to contribute to the work of the Oxford Trauma and Emergency Care group. As a Project Administrator, you will be assisting the Clinical Trial Managers of the group in the successful delivery of UK and Global Health research projects. You will provide comprehensive and efficient administration and office management for a number of projects in the field of Orthopaedic Trauma Research. As well as strong all-round administrative skills, the role involves use of electronic data capture software. You will be comfortable learning and working with software for data management activities. The Oxford Trauma and Emergency Care group conduct successful research in the UK and internationally. You will liaise with a large range of professionals at collaborating institutions, including partners based in Low and Middle Income Country (LMIC) settings. You might also be communicating with patients or their carers via telephone and email. You will work as part of a large multi-disciplinary team supporting studies through the various phases (set up, recruitment, data collection, monitoring, follow up, close out). The role will be mainly office based (with optional partial remote working), but you may be required on occasion to travel within the UK. You will have great general IT skills, with the ability to create and use spreadsheet applications to ensure monitoring is conducted according to local procedures. We expect you to have outstanding organisational and communication skills which you will use confidently. You will be self-motivated and friendly, and have a responsible and flexible approach to your workload. You will be able to maintain clear and accurate records, and be effective in meeting priorities and deadlines. Responsibilities • • • • • • • • • • • • Provide administration in compliance with all applicable legislation and guidance. Carry out day-to-day administrative coordination of project(s) with minimum supervision, reporting problems immediately, and providing updates to senior team members. Work within standard operating procedures, and monitor own projects and related junior staff to ensure quality assurance compliance. Provide administrative support for meetings, including management of diaries/electronic calendars, the preparation and distribution of agendas and taking, transcription and distribution of minutes. Follow-up of action points arising from meetings. Support the Trial Manager in the development of data report forms and documents related to database developmentto ensure timely database delivery. Answer trial-dedicated telephone calls and perform, when needed, follow-up study data collection with patients and carers via telephone. Ensure timely research data capture from collaborators. Track, organise, and collate data, maintain accurate, efficient filing and prepare new files. Maintain and assist in monitoring the budget processes including requisitions, orders and receipt of goods. Typing, audio-typing and formatting of letters, reports, minutes and presentations, and general correspondence/documents, using word processing, spreadsheet, e-mail and other software packages. Production of draft copy for standard letters, reports, and communications. Professional, responsive and courteous communication; deal directly with routine queries and ensure that messages are passed to the appropriate member of the team in a timely fashion. Be responsible for organising and planning own workload to meet research priorities, re adjusting plans to respond as situations change or arise. Provide support for junior staff. Move across projects with enthusiasm as directed by the Senior staff, and provide cover for other projects during times of absence. The job description is not intended to be rigid or inflexible and may include other duties and responsibilities as may be determined: you will be expected to work flexibly and respond positively to changing needs. 172438 JD Proj Admin_Global.docx 2 Selection criteria Essential selection criteria • • • • • • • • • Educated to at least A-Level standard or equivalent administrative qualifications/ experience. Ability to demonstrate excellent IT literacy, including a strong working knowledge of Word and Excel, with the ability to create and use spreadsheet applications. Evidence of following and working to detailed written instructions such as Standard Operating Procedures, associated with quality control or compliance, and ability to maintain clear and accurate records. Ability to demonstrate knowledge of data management, project quality management and monitoring activities. Effective verbal and written communication skills including an ability to effectively deal with telephone and email enquiries and proficiency in spoken/written English. Strong administrative experience including organising meetings and/or multiple appointment scheduling and minute taking. Self-motivated, able to work independently with a flexible attitude and ability to respond well to changing priorities and to meet deadlines. Demonstrate an understanding of data protection and other statutory requirements and professional guidelines. Experience of dealing with and communicating effectively and sensitively with a range of individuals and professionals, including those who have different cultural values from your own. Desirable selection criteria • • • • • Understanding of clinical governance and its implications and importance for research. Previous project management experience within a clinical research study. Familiarity with Electronic Data Capture systems. Experience of working within a registered clinical trials unit. Experience of research in Low and Middle Income Countries. Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks 172438 JD Proj Admin_Global.docx 3 About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners 172438 JD Proj Admin_Global.docx 4 across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognised centre of excellence for biomedical and clinical research and teaching. We are the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: www.medsci.ox.ac.uk Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching. Our mission is to discover the causes of musculoskeletal and inflammatory conditions to deliver excellent and innovative care that improves people’s quality of life. Our highly skilled teams have expertise in a broad range of areas, including orthopaedic surgery, inflammation, immunology, rheumatology, medical statistics, epidemiology, and clinical trials. We currently have 480 staff, approximately 120 post-graduate students and have a grant portfolio worth over £180 million. 172438 JD Proj Admin_Global.docx 5 The Botnar Research Centre enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research. It takes a multidisciplinary approach, encompassing orthopaedic, rehabilitation and rheumatology clinical scientists, bone oncologists, laboratory scientists, epidemiologists, engineers and statisticians. The Botnar also hosts the Oxford Clinical Trials Research Unit (OCTRU) and the Centre of Statistics in Medicine (CSM), providing excellent statistical support to all aspects of clinical research. The Botnar opened in 2002, with a large annex completed in 2013. The Botnar is now home to around 300 staff and postgraduate students enjoying the international and friendly atmosphere of this workplace and benefits from the vast knowledge of leading experts in the field of musculoskeletal research. To accommodate its rapid growth, the Centre has opened another wing in early 2022. The new space provides additional 1000m2 of office and 1000m2 of laboratory space. The laboratory space includes a GMP clean room facility suitable for the manufacturing of biomaterials for human implantation. Sharing the site of the Nuffield Orthopaedic Centre, the largest specialist academic musculoskeletal hospital in the UK, puts the Botnar in a unique position to foster the collaboration between basic scientists and clinicians, which is essential to success in medical research. The Kennedy Institute is a biomedical research centre uniquely bringing together discovery science and earlystage clinical research, to develop transformative new therapies for chronic inflammatory and musculoskeletal conditions. Broadly focused on the thematic areas of immunity and microbiome, inflammation biology and tissue remodelling and repair, the Institute’s research is relevant for a range of common diseases such as arthritis, inflammatory bowel disease, fibrosis and cancer. The Institute has capacity for up to 260 staff and students who work collaboratively across 25 research groups. This enables a multidisciplinary approach of molecular and cellular biology, combined with analysis of disease models, patient tissue samples and longitudinal clinical data. Collectively, these studies seek to uncover the biological processes that maintain tissue health and how these pathways break down in disease. Research at the Institute is supported by a suite of core technology platforms, as well as through strategic partnerships with other basic and clinical research centres in Oxford, across the UK and internationally. These state-of-the-art technologies include the Oxford-Zeiss Centre for Excellence and other advanced microscopy and imaging facilities, mass and flow cytometry, as well as capabilities for microbial genomics and functional microbiome studies made available through the Oxford Centre for Microbiome Studies. Complementing a strong programme of lab-based research, the Institute has established a core of expertise and technologies in data science including single cell genomics, statistical genetics, computational biology, and research informatics. A recent extension to the Institute building with a new third floor creates additional space purposely designed for computationally intensive research. A true trendsetter in innovative and transformational research, the Kennedy also boasts a relaxed and friendly atmosphere, revolving around its bright and airy atrium that provides a space for colleagues to meet over coffee and tea to talk about their research and beyond throughout the day. For more information please visit: http://www.kennedy.ox.ac.uk 172438 JD Proj Admin_Global.docx 6 Athena Swan The Athena SWAN Awards specifically recognise success in developing employment practices to further and support the careers of women in science, technology, engineering, maths and medicine (STEMM) departments in academia. In May 2015 the charter was expanded to recognise work undertaken in arts, humanities, social sciences, business and law (AHSSBL), and in professional and support roles. Within NDORMS, we feel that we have an established culture of equality but are using the process to spur on-going improvement that benefits everyone involved in the Department. Our on-going progress was rewarded in May 2014 with an Athena Swan Bronze Award and in October 2015 with a Silver Award. Our development in this area has resulted in a number of commitments to our staff, central to which are: ➢ establishing an open, supportive and family-friendly research environment ➢ supporting career progression through teaching programmes, personal development reviews and mentoring ➢ proactive communication of support policies such as flexible working, provision of leave, promotion and career support schemes NDORMS aims to actively promote the implementation of the University’s family-friendly policies to help foster a family friendly working environment, including provision of family leave (such as policies for maternity, paternity, parental, carers and adoption leave), flexible/part-time working and scheduling inclusive meetings. The University’s childcare services support staff with a Childcare Voucher Scheme to help staff save tax and national insurance on childcare costs, offer information on nursery providers and a nursery fee Salary Sacrifice Scheme, work in partnership with playscheme providers to help support families during school holidays and signpost staff to parenting, local authority and other organisations that help support families and parents. The Department is also committed to ensuring that staff undertaking part-time or flexible working receive the same access to benefits and entitlements as full-time staff, including the same opportunities for training and promotion, a pro-rata entitlement to leave including bank holidays and careful consideration of requests to work part-time (particularly for those by staff returning from maternity leave). For more information please visit: http://www.admin.ox.ac.uk/personnel/staffinfo/benefits/family/ and http://www.admin.ox.ac.uk/personnel/during/flexible/ We are also actively working to uphold the University’s aim of providing an inclusive environment and equal career opportunities by promoting equality, valuing diversity and maintaining a working, learning and social environment in which the rights and dignity of all staff are respected. Separate University policies are also in place to ensure race, disability and gender equality. For more information, please visit: http://www.admin.ox.ac.uk/eop/ 172438 JD Proj Admin_Global.docx 7 Oxford Trauma The role will be based in The Kadoorie Centre which is a purpose-built research and education facility at the John Radcliffe Hospital. Oxford Trauma and Emergency Care is one of the largest research groups in this field in the world, delivering a full spectrum of clinical effectiveness studies including randomised trials, observational studies and big data projects. The group has close links to basic and translational scientists at the Kennedy Centre and Botnar Research Institute. The Kadoorie Centre provides facilities for approximately 60 research staff, with a clinical skills centre and lecture theatre. Oxford Trauma and Emergency Care is a sub-theme within NDORMS and the Oxford BRC. It is one of the largest musculoskeletal trauma research groups in the world, delivering a full spectrum of clinical effectiveness studies including randomised trials, observational studies and big data projects. The group has close links to basic and translational scientists at the Kennedy Centre and Botnar Research Institute. The Oxford Trauma and Emergency Care Group is based in the Kadoorie Centre on the John Radcliffe site, providing a unique setting in which researchers interact with practising clinicians and have access to patients with the full range of traumatic injuries. The Kadoorie Centre provides facilities for approximately 60 research staff, with a clinical skills centre and lecture theatre. Clinical academic leadership is provided by Professor Matt Costa (Professor of Orthopaedic Trauma), Professor Dan Perry (Associate Professor of Paediatric Orthopaedic Trauma), Professor Steve Gwilym (Associate Professor of Orthopaedic Trauma) and Professor Simon Graham (Associate Professor of Orthopaedic Trauma Surgery). The team is supported by a full team of academic-related staff under Oxford Trauma and Emergency Care’s Research Manager, Dr Juul Achten. For more information please visit: https://www.ndorms.ox.ac.uk/Oxford-Trauma-and-Emergency-Care 172438 JD Proj Admin_Global.docx 8 How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of three referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs Non-technical questions about this job should be addressed to the recruiting department directly: hr@ndorms.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. 172438 JD Proj Admin_Global.docx 9 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacypolicy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/dataprotection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 172438 JD Proj Admin_Global.docx 10 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. 172438 JD Proj Admin_Global.docx 11
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We have an exciting opportunity for a Research Nurse to join our small, friendly research team, working under the supervision of Mrs Gail Lang at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences at the Nuffield Orthopaedic Centre, Oxford. As Research Nurse you will work within a multi-disciplinary setting between rheumatology, orthopaedics and physiotherapy. You will identify potential study participants and work with clinical teams in inpatient and outpatient settings to recruit eligible patients for musculoskeletal studies. You may on occasion be expected to travel to other OUHFT hospitals. Responsibilities will include; reviewing NHS case records, ensuring patient suitability according to study entry criteria, recording of study related information, obtaining informed consent to participate in specific studies, and ensuring the safe administration of treatments and drugs in line with the study protocols. You will also perform clinical procedures including venepuncture, height and weight measurements, history taking and study specific examinations and with training if required, ensuring the safe handling and quality of the labelling, processing and storage of biological samples. You will be an NMC Registered Nurse with experience demonstrating the appropriate competencies and skills for the role. You will have good computing skills including Microsoft Word, and the ability to manage your time well and work using your own initiative. Experience of working within a secondary care environment and a full UK driving licence are desirable. This is a part-time appointment (0.6 FTE, 22.5 hours per week) for 12 months in the first instance. This job includes the following duties which will require additional security pre-employment checks: • A satisfactory enhanced Disclosure and Barring Service check due to regulated activity involving children or ‘at risk’ adults. A lower grade offer may be made (Grade 5: £28,759 – £37,099 pro rata, p.a.) with commensurate reduction in responsibilities if a suitable candidate cannot be found to fill the Grade 6 position. The closing date for this position is 12:00 noon on Friday 03 May 2024. You will be required to upload a supporting statement and CV as part of your online application.
Job Description _________________________________________________________________________ Summary Job title Programme Manager for Functional Genomics Cluster (part-time) Division Medical Sciences Division Department Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Location Botnar Research Centre, Windmill Road, Oxford, OX3 7LD Grade and salary Grade 6: £32,332-£38,205 pro rata per annum Hours Part-time (50% FTE) Contract type Fixed-term (until 30/04/2028) Reporting to Prof Dominic Furniss Vacancy reference 172494 The role The UK Research and Innovation Musculoskeletal Functional Genomics Initiative Cluster (MSK Cluster) will begin in May 2024. This is one of four Functional Genomics clusters in the UK that have been funded by UKRI to accelerate the translation of genetic results into tangible benefits for patients. The MSK Cluster is led by Professor Dominic Furniss, and the funding provides support for researchers spanning the breadth of a translational medicine pipeline from basic genetics, bioinformatics and AI, through functional genomic readouts and tissue imaging, to human tissue models, organoids, and bioreactors. There is also a strong commitment to training and public engagement. We aim to accelerate translation of genetic findings across four key MSK diseases: osteoarthritis, carpal tunnel syndrome, frozen shoulder, and Dupuytren disease. You will be part of an interdisciplinary team of scientists and clinician researchers, spread across both Oxford and Manchester Universities, with international collaborators in Europe and the USA, as well as Industrial partners. In addition, it is anticipated that there will be close collaboration with the other funded clusters in Edinburgh and London. The post is responsible for the day-to-day operational management and communications to support the Cluster’s research programmes, including post-award grant management, financial monitoring and planning and organising events. You will have excellent communication and management skills and be able to prioritise tasks effectively in the context of a demanding and highly professional work environment. Responsibilities • Manage all non-academic administration functions for the Centre including, financial review and communications. • Actively participate in the Cluster management committee, planning the overall activities and strategic direction of the Cluster under guidance from Prof Furniss. • Provide updates and report issues or concerns to the Principal Investigator and/or the study team. Use initiative to tackle any practical difficulties encountered under their guidance. • Provide support to the Principal Investigator by undertaking tasks such as liaising with relevant individuals/teams/departments, drafting and submitting amendments; testing of the relevant project databases and management user accounts etc • Set up systems to manage/record information about on-going studies, team members and students, and be proactive in suggesting improvements to existing systems • Plan and organise within Cluster meetings and events as part of the operational strategy and development of the Cluster. • Plan and organise yearly external review and showcase meetings, and cross-Cluster meetings as directed by UKRI. • Write and submit budget requests and reports to funders to ensure compliance with award agreements. • Supervise the strategic dissemination of information for projects, with the support of the Department’s Communications team where appropriate; and maintain the digital profile of the Cluster through the website/social media. • Identify and engage with a range of stakeholders and audiences, providing timely and relevant information to them as appropriate. Act as primary point of contact for funders, industry partners and collaborators on all grants within the Cluster. • Be a key point of contact for all individuals/teams/departments involved in the project, facilitate the flow of information and communication between academics, students, other University Departments and services, 172494_JD .docx 2 industrial partners, and funding bodies to promote best practice and ensure communications are coordinated responding to or triaging queries as appropriate. • Collate and provide information to comply with grant terms. • Advise Cluster members, in Oxford and other academic institutions, on administrative and financial matters, often complex in nature, and provide training where required. • Contribute to development and implementation of policy, relevant Standard Operating Procedures (SOP) documents for the Cluster as required. • Develop and maintain networks with other UKRI Functional Genomics Clusters across the UK. • Be responsible for organising and planning own work to meet priorities, re-adjusting plans to respond as situations change or arise. • Undertake training as required by the post at the discretion of Principal Investigator and/or senior staff. • Proactively engaging in and supporting any relevant public engagement activities on group’s agenda Selection criteria Essential selection criteria • Educated to degree level or equivalent professional experience. • Knowledge of UK clinical research structures, regulatory and ethical systems, and experience of working to a high standard of Good Clinical Practice. • Proven management, resource planning and project management experience with ability to work independently and problem solve. • Proven experience organising internal and external events. • Excellent interpersonal skills, including diplomacy and the ability to inspire the confidence of senior colleagues. • Ability to work independently in a complex environment, taking initiative when necessary and prioritising effectively to meet deadlines. • Proficiency working with a range of computer-based and online applications, including website content management systems and clinical study databases. • Evidence of team working skills, including the ability to be comfortable and confident interacting with team members, administrative staff and the broader research community. • Computing literacy in e-mail, Microsoft Word, Excel and PowerPoint • Excellent interpersonal and communication skills; confidence and proficiency in spoken and written English. Desirable selection criteria • Experience working in higher education • Knowledge or interest in subject area of the department Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will 172494_JD .docx 3 contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognised centre of excellence for biomedical and clinical research and teaching. We are the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: www.medsci.ox.ac.uk Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching. Our mission is to discover the causes of musculoskeletal and inflammatory conditions to deliver excellent and innovative care that improves people’s quality of life. Our highly skilled teams have expertise in a broad range of areas, including orthopaedic surgery, inflammation, immunology, rheumatology, medical statistics, epidemiology, and clinical trials. We currently have 480 staff, approximately 120 post-graduate students and have a grant portfolio worth over £180 million. 172494_JD .docx 4 The Botnar Research Centre enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research. It takes a multidisciplinary approach, encompassing orthopaedic, rehabilitation and rheumatology clinical scientists, bone oncologists, laboratory scientists, epidemiologists, engineers and statisticians. The Botnar also hosts the Oxford Clinical Trials Research Unit (OCTRU) and the Centre of Statistics in Medicine (CSM), providing excellent statistical support to all aspects of clinical research. The Botnar opened in 2002, with a large annex completed in 2013. The Botnar is now home to around 300 staff and postgraduate students enjoying the international and friendly atmosphere of this workplace and benefits from the vast knowledge of leading experts in the field of musculoskeletal research. To accommodate its rapid growth, the Centre has opened another wing in early 2022. The new space provides additional 1000m2 of office and 1000m2 of laboratory space. The laboratory space includes a GMP clean room facility suitable for the manufacturing of biomaterials for human implantation. Sharing the site of the Nuffield Orthopaedic Centre, the largest specialist academic musculoskeletal hospital in the UK, puts the Botnar in a unique position to foster the collaboration between basic scientists and clinicians, which is essential to success in medical research. The Kennedy Institute is a biomedical research centre uniquely bringing together discovery science and earlystage clinical research, to develop transformative new therapies for chronic inflammatory and musculoskeletal conditions. Broadly focused on the thematic areas of immunity and microbiome, inflammation biology and tissue remodelling and repair, the Institute’s research is relevant for a range of common diseases such as arthritis, inflammatory bowel disease, fibrosis and cancer. The Institute has capacity for up to 260 staff and students who work collaboratively across 25 research groups. This enables a multidisciplinary approach of molecular and cellular biology, combined with analysis of disease models, patient tissue samples and longitudinal clinical data. Collectively, these studies seek to uncover the biological processes that maintain tissue health and how these pathways break down in disease. Research at the Institute is supported by a suite of core technology platforms, as well as through strategic partnerships with other basic and clinical research centres in Oxford, across the UK and internationally. These state-of-the-art technologies include the Oxford-Zeiss Centre for Excellence and other advanced microscopy and imaging facilities, mass and flow cytometry, as well as capabilities for microbial genomics and functional microbiome studies made available through the Oxford Centre for Microbiome Studies. Complementing a strong programme of lab-based research, the Institute has established a core of expertise and technologies in data science including single cell genomics, statistical genetics, computational biology, and research informatics. A recent extension to the Institute building with a new third floor creates additional space purposely designed for computationally intensive research. A true trendsetter in innovative and transformational research, the Kennedy also boasts a relaxed and friendly atmosphere, revolving around its bright and airy atrium that provides a space for colleagues to meet over coffee and tea to talk about their research and beyond throughout the day. For more information please visit: http://www.kennedy.ox.ac.uk 172494_JD .docx 5 Athena Swan The Athena SWAN Awards specifically recognise success in developing employment practices to further and support the careers of women in science, technology, engineering, maths and medicine (STEMM) departments in academia. In May 2015 the charter was expanded to recognise work undertaken in arts, humanities, social sciences, business and law (AHSSBL), and in professional and support roles. Within NDORMS, we feel that we have an established culture of equality but are using the process to spur on-going improvement that benefits everyone involved in the Department. Our on-going progress was rewarded in May 2014 with an Athena Swan Bronze Award and in October 2015 with a Silver Award. Our development in this area has resulted in a number of commitments to our staff, central to which are: ➢ establishing an open, supportive and family-friendly research environment ➢ supporting career progression through teaching programmes, personal development reviews and mentoring ➢ proactive communication of support policies such as flexible working, provision of leave, promotion and career support schemes NDORMS aims to actively promote the implementation of the University’s family-friendly policies to help foster a family friendly working environment, including provision of family leave (such as policies for maternity, paternity, parental, carers and adoption leave), flexible/part-time working and scheduling inclusive meetings. The University’s childcare services support staff with a Childcare Voucher Scheme to help staff save tax and national insurance on childcare costs, offer information on nursery providers and a nursery fee Salary Sacrifice Scheme, work in partnership with playscheme providers to help support families during school holidays and signpost staff to parenting, local authority and other organisations that help support families and parents. The Department is also committed to ensuring that staff undertaking part-time or flexible working receive the same access to benefits and entitlements as full-time staff, including the same opportunities for training and promotion, a pro-rata entitlement to leave including bank holidays and careful consideration of requests to work part-time (particularly for those by staff returning from maternity leave). For more information please visit: http://www.admin.ox.ac.uk/personnel/staffinfo/benefits/family/ and http://www.admin.ox.ac.uk/personnel/during/flexible/ We are also actively working to uphold the University’s aim of providing an inclusive environment and equal career opportunities by promoting equality, valuing diversity and maintaining a working, learning and social environment in which the rights and dignity of all staff are respected. Separate University policies are also in place to ensure race, disability and gender equality. For more information, please visit: http://www.admin.ox.ac.uk/eop/ 172494_JD .docx 6 How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs Non-technical questions about this job should be addressed to the recruiting department directly:hr@ndorms.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. 172494_JD .docx 7 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacypolicy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/dataprotection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 172494_JD .docx 8 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. 172494_JD .docx 9
Current vacancies at the University of Oxford
NDORMS, Oxford Trauma and Emergency Care, Kadoorie Critical Care Research Centre, John Radcliffe Hospital, Oxford, OX3 9DU
NDORMS, Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3 7FY
License
_________________________________________________________________________ Job description and selection criteria Job title Research Assistant in Health Data Sciences Division Medical Sciences Division Department Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Location Botnar Research Centre, Nuffield Orthopaedic Centre, Windmill Road, Oxford Grade and salary Grade 6: £32,322 to £38,205 per annum Hours Full time Contract type Fixed-term for 24 months Reporting to Dr Marti Catala-Sabate Vacancy reference 172348 Research topic Health Data Sciences Principal Investigators Prof Daniel Prieto-Alhambra, Dr Edward Burn, Dr Mati Catala-Sabate Project web site See group’s website https://www.ndorms.ox.ac.uk/research/MusculoskeletalPharmacoepidemiology Recent publications See ‘Selected Publications’ in the group’s website https://www.ndorms.ox.ac.uk/research/MusculoskeletalPharmacoepidemiology Technical skills Programming Health Data Sciences Overview of the role The NDORMS Pharmaco- and Device epidemiology research group is involved in a number of national and international studies exploring the conditions of use (adherence, compliance, off and on-label use) of a number of drugs, procedures and devices for the treatment of various conditions in 'real world' actual practice conditions. We collaborate with researchers from around the globe to improve our understanding of the safety and effectiveness of new and long-licensed medications, vaccines, and devices. Project details You will work on the following key areas of research: a) To programme analytical pipelines to study the use of medicinal products using national and international real world data. b) To programme analytical pipelines to compare the (beneficial and harmful) effects of medicinal products. c) To test and improve the existing methods for the study of the use, safety and effectiveness of vaccines and medicines using observational data. d) To support the programming of analytical pipelines for distributed network analyses to answer questions on the use, safety and effectiveness of vaccines and medicines using real world data. There are ongoing studies in our current work to support each of these areas of research through local, national and international collaborations Responsibilities/duties 1. Your primary duty is to contribute to the programming of analytical pipelines for the analysis of routinely collected data mapped to the OMOP Common Data Model. 2. You will prepare analytical packages to run a number of pre-specified analyses in the areas above. 3. You will analyse real world data to address regulatory questions related to the prevalence/incidence of disease, use of medicines/vaccines, and the risks or benefits of medicines/vaccines or devices 4. You will conduct and support research activities based on your expertise in: programming; engineering; biostatistics; pharmaco-epidemiology; propensity scores and/or weighting. 5. Manage own research and administrative activities, within guidelines provided by senior colleagues 6. Contribute to wider project planning, including ideas for new research projects 7. Determine the most appropriate methodologies to test hypotheses, and identify suitable alternatives if technical problems arise 8. Gather, analyse, and present scientific data from a variety of sources 9. Contribute to scientific reports and journal articles and the presentation of data/papers at conferences Additional duties include: 172348_JD_final.docx 2 1. To be proactive in organising and prioritising workload, managing own time effectively, highlighting problems as they arise and proposing possible solutions within available resources. 2. Maintaining effective communication with members of the research team working with staff in other collaborating centres as required. 3. To contribute to the drafting of reports and publications in peer-reviewed journals. 4. To give presentations to multidisciplinary groups and attend local, national and international conferences for the purpose of disseminating research results. 5. Managing own workload to ensure optimal support to studies, and working flexibly in the team to make the best use of time. Selection criteria Essential • A relevant BA or MSc degree in Mathematics, Engineering, or a related field • Experience in biostatistics and/or health data sciences • Experience in the programming of R packages • Knowledge of medical statistics and experience analysing large datasets • Previous training in real world evidence and/or pharmaco-epidemiology methods • Ability to demonstrate practical use of information technology systems, in particular database systems, Microsoft Office packages, e-mail and Internet. • Ability to work within multi-disciplinary teams and independently • Self-motivated with proven organisational and time management skills • Ability to communicate effectively with colleagues in any discipline • Demonstrate an ability to follow departmental guidance in handling sensitive and personal information, including complying with current data protection legislation Desirable • Experience in the analysis and interpretation of OMOP-mapped data • Experience in propensity scores, overlap weighting, inverse probability weighting and/or similar methods • Expertise in pharmaco or vaccine epidemiology • Experience working with electronic medical records/routinely collected data • Experience working within an academic environment Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. 172348_JD_final.docx 3 Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognised centre of excellence for biomedical and clinical research and teaching. We are the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: www.medsci.ox.ac.uk Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching. Our mission is to discover the causes of musculoskeletal and inflammatory conditions to deliver excellent and innovative care that improves people’s quality of life. Our highly skilled teams 172348_JD_final.docx 4 have expertise in a broad range of areas, including orthopaedic surgery, inflammation, immunology, rheumatology, medical statistics, epidemiology, and clinical trials. We currently have 460 staff, 100 students and have a grants portfolio worth over £148 million, and an annual turnover in excess of £38 million. The Botnar Research Centre enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research. It takes a multidisciplinary approach, encompassing orthopaedic, rehabilitation and rheumatology clinical scientists, bone oncologists, laboratory scientists, epidemiologists, engineers and statisticians. The Botnar also hosts the Oxford Clinical Trials Research Unit (OCTRU) and the Centre of Statistics in Medicine (CSM), providing excellent statistical support to all aspects of clinical research. The Botnar opened in 2002, with a large annex completed in 2013. The Botnar is now home to around 300 staff and postgraduate students enjoying the international and friendly atmosphere of this workplace and benefits from the vast knowledge of leading experts in the field of musculoskeletal research. To accommodate its rapid growth, the Centre will open another wing in 2021. This will provide research space for the new Professor of Biomaterials. The new space will include 1000m 2 of office and 1000m2 of laboratory space. The laboratory space includes a GMP clean room facility suitable for the manufacturing of biomaterials for human implantation. Sharing the site of the Nuffield Orthopaedic Centre, the largest specialist academic musculoskeletal hospital in the UK, puts the Botnar in a unique position to foster the collaboration between basic scientists and clinicians, which is essential to success in medical research. The Kennedy Institute of Rheumatology is world famous for its discovery of anti-TNF therapy for the treatment of chronic inflammatory diseases like rheumatoid arthritis, which has established the current standard of care and heralded the wider use of biologic drugs to treat chronic disease. The Institute carries out fundamental research in the areas of immunity and microbiome, inflammation biology and tissue remodelling and regeneration, with the long-term objective of ‘translating’ this research into clinical application. The major diseases of interest are rheumatoid arthritis, osteoarthritis, inflammatory bowel disease and cancer. The Institute provides space to house close to 200 researchers and support staff. For more information please visit: http://www.kennedy.ox.ac.uk Athena Swan 172348_JD_final.docx 5 The Athena SWAN Awards specifically recognise success in developing employment practices to further and support the careers of women in science, technology, engineering, maths and medicine (STEMM) departments in academia. In May 2015 the charter was expanded to recognise work undertaken in arts, humanities, social sciences, business and law (AHSSBL), and in professional and support roles. Within NDORMS, we feel that we have an established culture of equality but are using the process to spur on-going improvement that benefits everyone involved in the Department. Our on-going progress was rewarded in May 2014 with an Athena Swan Bronze Award and in October 2015 with a Silver Award. Our development in this area has resulted in a number of commitments to our staff, central to which are: ➢ establishing an open, supportive and family-friendly research environment ➢ supporting career progression through teaching programmes, personal development reviews and mentoring ➢ proactive communication of support policies such as flexible working, provision of leave, promotion and career support schemes NDORMS aims to actively promote the implementation of the University’s family-friendly policies to help foster a family friendly working environment, including provision of family leave (such as policies for maternity, paternity, parental, carers and adoption leave), flexible/part-time working and scheduling inclusive meetings. The University’s childcare services support staff with a Childcare Voucher Scheme to help staff save tax and national insurance on childcare costs, offer information on nursery providers and a nursery fee Salary Sacrifice Scheme, work in partnership with playscheme providers to help support families during school holidays and signpost staff to parenting, local authority and other organisations that help support families and parents. The Department is also committed to ensuring that staff undertaking part-time or flexible working receive the same access to benefits and entitlements as full-time staff, including the same opportunities for training and promotion, a pro-rata entitlement to leave including bank holidays and careful consideration of requests to work part-time (particularly for those by staff returning from maternity leave). For more information please visit: http://www.admin.ox.ac.uk/personnel/staffinfo/benefits/family/ and http://www.admin.ox.ac.uk/personnel/during/flexible/ We are also actively working to uphold the University’s aim of providing an inclusive environment and equal career opportunities by promoting equality, valuing diversity and maintaining a working, learning and social environment in which the rights and dignity of all staff are respected. Separate University policies are also in place to ensure race, disability and gender equality. For more information, please visit: http://www.admin.ox.ac.uk/eop/ 172348_JD_final.docx 6 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Help and support is available from: https://hrsystems.admin.ox.ac.uk/recruitment-support If you require any further assistance please email recruitment.support@admin.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our e-recruitment system to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. 172348_JD_final.docx 7 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for all academic posts and some academic-related posts. The University has adopted an EJRA of 30 September before the 69th birthday for all academic and academic-related staff in posts at grade 8 and above. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra For existing employees, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra There is no normal or fixed age at which staff in posts at grades 1–7 have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 172348_JD_final.docx 8 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to My Family Care, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare. The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. 172348_JD_final.docx 9
Standard Grade 6: £32,332-£38,205 (pro rata) p.a.
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_________________________________________________________________________ Job description and selection criteria Job title Research Assistant in Epidemiology and Health Data Sciences Division Medical Sciences Division Department Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Location Botnar Research Centre, Nuffield Orthopaedic Centre, Windmill Road, Oxford Grade and salary Grade 6: £32,322 to £38,205 per annum Hours Full time Contract type Fixed-term for 2 years Reporting to Dr Annika Jodicke Vacancy reference 172311 Research topic Health Data Sciences Principal Investigators Prof Daniel Prieto-Alhambra Project web site See group’s website https://www.ndorms.ox.ac.uk/research/MusculoskeletalPharmacoepidemiology Recent publications See Prof D Prieto-Alhambra’s website https://www.ndorms.ox.ac.uk/team/daniel-prieto-alhambra Technical skills Medical Statistics Epidemiology Health Data Sciences Overview of the role The NDORMS Pharmaco- and Device epidemiology research group is involved in a number of national and international studies exploring the conditions of use (adherence, compliance, off and on-label use) of a number of drugs, procedures and devices for the treatment of various conditions in 'real world' actual practice conditions. We collaborate with researchers from around the globe to improve our understanding of the safety and effectiveness of new and long-licensed medications, vaccines, and devices. Project details You will work on the following key areas of research: a) To support the planning and management of studies on the use of medicinal products in national and international real world data from electronic health records, health claims, and registries b) To conduct analyses on the descriptive epidemiology and burden of various conditions including neurodegenerative disease and cancer among others in national and international real world data c) To test and improve the existing methods for the study of the use, safety and effectiveness of various medicines using observational data d) To contribute to the development and validation of computable phenotypes for the identification of specific cohorts in national and international real world data There are ongoing studies in our current work to support each of these areas of research through local, national and international collaborations Responsibilities/duties 1. Your primary duties are to support the analysis and management for studies usingroutinely collected data mapped to the OMOP Common Data Model under the supervision of more senior epidemiologists and data scientists; and to contribute to the development and validation of computable phenotypes. 2. You will contribute to the development of study documentation for the above studies including study protocols and scientific reports. 3. You will use R packages to run a number of pre-specified analyses in the areas above under the supervision of more senior colleagues in the team 4. You will conduct and support research activities based on your expertise in: epidemiology AND/OR biostatistics AND/OR pharmaco-epidemiology AND/OR causal inference methods 5. Manage own research and administrative activities, within guidelines provided by senior colleagues 6. Contribute to wider project planning, including ideas for new research projects 7. Gather, analyse, and present scientific data from a variety of sources 8. Contribute to scientific reports and journal articles and the presentation of data/papers at conferences and other scientific meetings Additional duties include: 172311_JD_final.docx 2 1. To be proactive in organising and prioritising workload, managing own time effectively, highlighting problems as they arise and proposing possible solutions within available resources. 2. Maintaining effective communication with members of the research team working with staff in other collaborating centres as required. 3. To contribute to the drafting of reports and publications in peer-reviewed journals. 4. To give presentations to multidisciplinary groups and attend local, national and international conferences for the purpose of disseminating research results. 5. Managing own workload to ensure optimal support to studies and working flexibly in the team to make the best use of time. Selection criteria Essential • A relevant post-graduate degree in Epidemiology or a related field • Experience in biostatistics and/or health data sciences • Experience in programming statistical analyses, preferably in R • Experience in writing scientific documents, e.g. study reports, manuscripts • Ability to demonstrate practical use of information technology systems, in particular database systems, Microsoft Office packages, e-mail and Internet • Ability to work within multi-disciplinary teams and independently • Self-motivated with proven organizational and time management skills • Ability to communicate well (both verbally and in writing) with people from diverse disciplines • Demonstrate an ability to follow departmental guidance in handling sensitive and personal information, including complying with current data protection legislation Desirable • Experience in the analysis or interpretation of OMOP-mapped data • Experience in generating phenotypes • Expertise in pharmaco-epidemiology or causal inference methods • MSc in Data Sciences, Epidemiology, or Medical Statistics • Experience working with electronic medical records/routinely collected/real world data • Experience of working within an academic environment Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. 172311_JD_final.docx 3 Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for 172311_JD_final.docx 4 university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognised centre of excellence for biomedical and clinical research and teaching. We are the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: www.medsci.ox.ac.uk Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching. Our mission is to discover the causes of musculoskeletal and inflammatory conditions to deliver excellent and innovative care that improves people’s quality of life. Our highly skilled teams have expertise in a broad range of areas, including orthopaedic surgery, inflammation, immunology, rheumatology, medical statistics, epidemiology, and clinical trials. We currently have 460 staff, 100 students and have a grants portfolio worth over £148 million, and an annual turnover in excess of £38 million. The Botnar Research Centre enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research. It takes a multidisciplinary approach, encompassing orthopaedic, rehabilitation and rheumatology clinical scientists, bone oncologists, laboratory scientists, epidemiologists, engineers and statisticians. The Botnar also hosts the Oxford Clinical Trials Research Unit (OCTRU) and the Centre of Statistics in Medicine (CSM), providing excellent statistical support to all aspects of clinical research. The Botnar opened in 2002, with a large annex completed in 2013. The Botnar is now home to around 300 staff and postgraduate students enjoying the international and friendly atmosphere 172311_JD_final.docx 5 of this workplace and benefits from the vast knowledge of leading experts in the field of musculoskeletal research. To accommodate its rapid growth, the Centre will open another wing in 2021. This will provide research space for the new Professor of Biomaterials. The new space will include 1000m2 of office and 1000m2 of laboratory space. The laboratory space includes a GMP clean room facility suitable for the manufacturing of biomaterials for human implantation. Sharing the site of the Nuffield Orthopaedic Centre, the largest specialist academic musculoskeletal hospital in the UK, puts the Botnar in a unique position to foster the collaboration between basic scientists and clinicians, which is essential to success in medical research. The Kennedy Institute of Rheumatology is world famous for its discovery of anti-TNF therapy for the treatment of chronic inflammatory diseases like rheumatoid arthritis, which has established the current standard of care and heralded the wider use of biologic drugs to treat chronic disease. The Institute carries out fundamental research in the areas of immunity and microbiome, inflammation biology and tissue remodelling and regeneration, with the long-term objective of ‘translating’ this research into clinical application. The major diseases of interest are rheumatoid arthritis, osteoarthritis, inflammatory bowel disease and cancer. The Institute provides space to house close to 200 researchers and support staff. For more information please visit: http://www.kennedy.ox.ac.uk 172311_JD_final.docx 6 Athena Swan The Athena SWAN Awards specifically recognise success in developing employment practices to further and support the careers of women in science, technology, engineering, maths and medicine (STEMM) departments in academia. In May 2015 the charter was expanded to recognise work undertaken in arts, humanities, social sciences, business and law (AHSSBL), and in professional and support roles. Within NDORMS, we feel that we have an established culture of equality but are using the process to spur on-going improvement that benefits everyone involved in the Department. Our on-going progress was rewarded in May 2014 with an Athena Swan Bronze Award and in October 2015 with a Silver Award. Our development in this area has resulted in a number of commitments to our staff, central to which are: ➢ establishing an open, supportive and family-friendly research environment ➢ supporting career progression through teaching programmes, personal development reviews and mentoring ➢ proactive communication of support policies such as flexible working, provision of leave, promotion and career support schemes NDORMS aims to actively promote the implementation of the University’s family-friendly policies to help foster a family friendly working environment, including provision of family leave (such as policies for maternity, paternity, parental, carers and adoption leave), flexible/part-time working and scheduling inclusive meetings. The University’s childcare services support staff with a Childcare Voucher Scheme to help staff save tax and national insurance on childcare costs, offer information on nursery providers and a nursery fee Salary Sacrifice Scheme, work in partnership with playscheme providers to help support families during school holidays and signpost staff to parenting, local authority and other organisations that help support families and parents. The Department is also committed to ensuring that staff undertaking part-time or flexible working receive the same access to benefits and entitlements as full-time staff, including the same opportunities for training and promotion, a prorata entitlement to leave including bank holidays and careful consideration of requests to work part-time (particularly for those by staff returning from maternity leave). For more information please visit: http://www.admin.ox.ac.uk/personnel/staffinfo/benefits/family/ and http://www.admin.ox.ac.uk/personnel/during/flexible/ We are also actively working to uphold the University’s aim of providing an inclusive environment and equal career opportunities by promoting equality, valuing diversity and maintaining a working, learning and social environment in which the rights and dignity of all staff are respected. Separate University policies are also in place to ensure race, disability and gender equality. For more information, please visit: http://www.admin.ox.ac.uk/eop/ 172311_JD_final.docx 7 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Help and support is available from: https://hrsystems.admin.ox.ac.uk/recruitment-support If you require any further assistance please email recruitment.support@admin.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our e-recruitment system to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. 172311_JD_final.docx 8 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for all academic posts and some academic-related posts. The University has adopted an EJRA of 30 September before the 69th birthday for all academic and academic-related staff in posts at grade 8 and above. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra For existing employees, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra There is no normal or fixed age at which staff in posts at grades 1–7 have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 172311_JD_final.docx 9 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to My Family Care, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare. The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. 172311_JD_final.docx 10
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We have an exciting opportunity for a Postdoctoral Health Data Scientist to join the research group led by Associate Professor Sara Khalid at the Centre for Statistics in Medicine, the Botnar Research Centre, NDORMS, University of Oxford. Welcome to the Planetary Health Informatics Group. We combine fair and safe artificial intelligence, remote monitoring technology and clinical epidemiology to study international real-world health, environment, and climate data, for the prevention and treatment of human diseases and to fill the gaps in global health, leveraging common data models and federated network analytics. As a Postdoctoral Data Scientist, you will develop analysis plans, protocols, ethical (and similar panel) submissions, governance and regulatory submissions as required for ongoing and future studies. You will generate and analyse real world health data assets, analyse data following pre-specified analysis plans and/or approved protocols and prepare working theories and analyse quantitative data from a variety of sources, reviewing and refining theories as appropriate. You will carry out collaborative projects with colleagues in partner institutions, and research groups, present papers at conferences or public meetings, lead and support the drafting of scientific manuscripts for dissemination as well as manage your own academic research and administrative activities. You will hold a Doctoral (or be near completion) or MSc degree in applied/medical statistics, bio/medical engineering, health data sciences, health informatics, computer science, clinical/environmental epidemiology, or a similar field. Demonstrable advanced skills in programming in Python, SQL, or similar languages, advanced skills and expertise in R programming and to communicate results effectively in writing and verbally with colleagues in any discipline are essential. Experience designing and conducting cohort, case-control, and similar studies, experience in prediction modelling and experience in common data models are desirable. This is a full-time post, fixed-term contract for 21 months. A lower grade offer may be made (Grade 6: £32,332- £33,205 p.a.) with commensurate reduction in responsibilities (and a change in job title to Research Assistant in Health Data Sciences) if a suitable candidate cannot be found to fill the Grade 7 position. The closing date for applications is 12 noon on 08/05/2024. You will be required to upload a supporting statement as part of your online application. Please quote 172572 on all correspondence.
_________________________________________________________________________ Summary Job title Project Manager (Maternity Cover) Division Medical Sciences Division Department Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Location Botnar Research Centre, Windmill Road, Oxford, OX3 7LD Grade and salary Grade 6: £32,332-£38,205 per annum Hours Contract type Full time Maternity Cover (6 months) Reporting to James Fullerton, Associate Professor of Clinical Therapeutics Vacancy reference 172013 This role is available from 27/05/2024. This role can be offered as a secondment opportunity. Additional information A lower grade offer may be made (Grade 5: £28,759- £33,966 p.a.) with commensurate reduction in responsibilities (and a change in job title to Project Administrator) if a suitable candidate cannot be found to fill the Grade 6 position. The role This role will contribute to the successful running of the growing portfolio of Experimental Medicine studies involving human immune challenge being conducted in Oxford and led by A/Prof James Fullerton. These tend to involve healthy volunteers, be of small size (<50 participants) and will largely be conducted at a single site. Reporting directly to A/Prof Fullerton, the post holder will take responsibility for the coordination of all areas of trial operationalisation including site set up, data management and site closure activities. The post holder will utilise their clinical trials experience and knowledge to provide administrative and technical support to A/Prof Fullerton’s group. It is anticipated the post holder will also contribute to protocol development, obtaining relevant ethical and regulatory approvals, as well as directly contributing to day-to-day operational issues including screening and scheduling participants study visits. The post holder will be expected to work independently with minimal supervision across a number of studies within the group, adapting to current demands. It is hoped the post holder will eventually contribute to overall strategic and operational leadership of the group. Maternity leave cover post This post is to cover the absence of the substantive postholder, who is taking a period of maternity leave. The post is available for 6 months or the actual return of the substantive postholder, or the resignation of the substantive postholder and employment of a new postholder, whichever is the earliest. Responsibilities 1. Take responsibility for the coordination of specific areas of trial management such as site set up, site management, data collection, site closure. 2. Provide updates and report issues or concerns to the Principal Investigator and/or the study team. Use initiative to tackle any practical difficulties encountered under their guidance. 3. Contribute to the production and updating of trial documents, Standard Operating Procedures, training material and trial specific instructions, and contribute to the maintenance of the TMF or equivalent documents. 4. Provide support to the Principal Investigator by undertaking tasks such as liaising with relevant individuals/teams/departments (e.g. Pharmacy, Radiology); drafting and submitting amendments; testing of the trial databases and management user accounts 5. Set up systems to manage/record information about on-going studies, team members and students, and be proactive in suggesting improvements to existing systems. 6. Be a key point of contact for all individuals/teams/departments involved in study delivery as well as both potential and enrolled participants through the management of the trial email account, responding to or triaging queries as appropriate. 7. Line manage and/or provide training to junior members of staff, including students. 8. Provide administrative support to both trials and associated group activities such as by organising and supporting trial meetings, managing supplies and payments (including for laboratory activity), coordinating mail-outs and contributing to reports where needed. 9. Provide cover for study team absences, alerting senior staff to any newly arising issues. 10. Be responsible for organising and planning own work to meet trial priorities, re-adjusting plans to respond as situations change or arise. 11. Be willing to attend external meetings/visits 12. Undertake all activities in line with Standard Operating Procedures and in compliance with the Research Governance Framework for Health and Social Care, the Data Protection Act and other applicable legislation and guidance. 13. Undertake training as required by the post at the discretion of Principal Investigator and/or senior staff. Selection criteria Essential selection criteria 1. Educated to at least BSc level or equivalent qualifications/experience. 2. Knowledge of UK clinical research structures, regulatory and ethical systems, and experience of working to a high standard of Good Clinical Practice. 3. Previous experience in trial coordination/administration/support role. 172013 Project Manager_JD.docx 2 4. Ability to work independently and problem solve. 5. Evidence of effective organisational skills including the ability to prioritise workload and be adaptable to changing priorities. 6. Demonstrate a critical and intelligent attention to detail and high standards of accuracy. 7. Proven administrative and office management skills including IT literacy and competency in Microsoft Word, Excel and Outlook. 8. Ability to follow written procedures and set up systems to comply with such procedures. 9. Evidence of team working skills, including the ability to be comfortable and confident interacting with team members, administrative staff and the broader research community. 10. Excellent interpersonal and communication skills; confidence and proficiency in spoken and written English. 11. Demonstrate an understanding of data protection and other statutory requirements and professional guidelines, such as Good Clinical Practice guidelines. 12. Demonstrate an ability to follow departmental guidance in handling sensitive and personal information, including complying with current data protection legislation. Desirable selection criteria 1. Experience of UK clinical research structures, regulatory and ethical systems. 2. Experience of data management relating to research participants, including use of REDCap 3. Education in or experience of conducting immunology research 4. Proven ability to work within and co-ordinate professional multidisciplinary teams, including those involved in delivering clinical care Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks 172013 Project Manager_JD.docx 3 About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognised centre of excellence for biomedical and clinical research and teaching. We are the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: www.medsci.ox.ac.uk Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching. Our mission is to discover the causes of musculoskeletal and inflammatory conditions to deliver excellent and innovative care that improves people’s quality of life. Our highly skilled teams have expertise in a broad range of areas, including orthopaedic surgery, inflammation, immunology, rheumatology, medical statistics, epidemiology, and clinical trials. We currently have 480 staff, approximately 120 post-graduate students and have a grant portfolio worth over £180 million. 172013 Project Manager_JD.docx 4 The Botnar Research Centre enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research. It takes a multidisciplinary approach, encompassing orthopaedic, rehabilitation and rheumatology clinical scientists, bone oncologists, laboratory scientists, epidemiologists, engineers and statisticians. The Botnar also hosts the Oxford Clinical Trials Research Unit (OCTRU) and the Centre of Statistics in Medicine (CSM), providing excellent statistical support to all aspects of clinical research. The Botnar opened in 2002, with a large annex completed in 2013. The Botnar is now home to around 300 staff and postgraduate students enjoying the international and friendly atmosphere of this workplace and benefits from the vast knowledge of leading experts in the field of musculoskeletal research. To accommodate its rapid growth, the Centre has opened another wing in early 2022. The new space provides additional 1000m2 of office and 1000m2 of laboratory space. The laboratory space includes a GMP clean room facility suitable for the manufacturing of biomaterials for human implantation. Sharing the site of the Nuffield Orthopaedic Centre, the largest specialist academic musculoskeletal hospital in the UK, puts the Botnar in a unique position to foster the collaboration between basic scientists and clinicians, which is essential to success in medical research. The Kennedy Institute is a biomedical research centre uniquely bringing together discovery science and earlystage clinical research, to develop transformative new therapies for chronic inflammatory and musculoskeletal conditions. Broadly focused on the thematic areas of immunity and microbiome, inflammation biology and tissue remodelling and repair, the Institute’s research is relevant for a range of common diseases such as arthritis, inflammatory bowel disease, fibrosis and cancer. The Institute has capacity for up to 260 staff and students who work collaboratively across 25 research groups. This enables a multidisciplinary approach of molecular and cellular biology, combined with analysis of disease models, patient tissue samples and longitudinal clinical data. Collectively, these studies seek to uncover the biological processes that maintain tissue health and how these pathways break down in disease. Research at the Institute is supported by a suite of core technology platforms, as well as through strategic partnerships with other basic and clinical research centres in Oxford, across the UK and internationally. These state-of-the-art technologies include the Oxford-Zeiss Centre for Excellence and other advanced microscopy and imaging facilities, mass and flow cytometry, as well as capabilities for microbial genomics and functional microbiome studies made available through the Oxford Centre for Microbiome Studies. Complementing a strong programme of lab-based research, the Institute has established a core of expertise and technologies in data science including single cell genomics, statistical genetics, computational biology, and research informatics. A recent extension to the Institute building with a new third floor creates additional space purposely designed for computationally intensive research. A true trendsetter in innovative and transformational research, the Kennedy also boasts a relaxed and friendly atmosphere, revolving around its bright and airy atrium that provides a space for colleagues to meet over coffee and tea to talk about their research and beyond throughout the day. 172013 Project Manager_JD.docx 5 For more information please visit: http://www.kennedy.ox.ac.uk Athena Swan The Athena SWAN Awards specifically recognise success in developing employment practices to further and support the careers of women in science, technology, engineering, maths and medicine (STEMM) departments in academia. In May 2015 the charter was expanded to recognise work undertaken in arts, humanities, social sciences, business and law (AHSSBL), and in professional and support roles. Within NDORMS, we feel that we have an established culture of equality but are using the process to spur on-going improvement that benefits everyone involved in the Department. Our on-going progress was rewarded in May 2014 with an Athena Swan Bronze Award and in October 2015 with a Silver Award. Our development in this area has resulted in a number of commitments to our staff, central to which are: ➢ establishing an open, supportive and family-friendly research environment ➢ supporting career progression through teaching programmes, personal development reviews and mentoring ➢ proactive communication of support policies such as flexible working, provision of leave, promotion and career support schemes NDORMS aims to actively promote the implementation of the University’s family-friendly policies to help foster a family friendly working environment, including provision of family leave (such as policies for maternity, paternity, parental, carers and adoption leave), flexible/part-time working and scheduling inclusive meetings. The University’s childcare services support staff with a Childcare Voucher Scheme to help staff save tax and national insurance on childcare costs, offer information on nursery providers and a nursery fee Salary Sacrifice Scheme, work in partnership with playscheme providers to help support families during school holidays and signpost staff to parenting, local authority and other organisations that help support families and parents. The Department is also committed to ensuring that staff undertaking part-time or flexible working receive the same access to benefits and entitlements as full-time staff, including the same opportunities for training and promotion, a pro-rata entitlement to leave including bank holidays and careful consideration of requests to work part-time (particularly for those by staff returning from maternity leave). For more information please visit: http://www.admin.ox.ac.uk/personnel/staffinfo/benefits/family/ and http://www.admin.ox.ac.uk/personnel/during/flexible/ We are also actively working to uphold the University’s aim of providing an inclusive environment and equal career opportunities by promoting equality, valuing diversity and maintaining a working, learning and social environment in which the rights and dignity of all staff are respected. Separate University policies are also in place to ensure race, disability and gender equality. For more information, please visit: http://www.admin.ox.ac.uk/eop/ 172013 Project Manager_JD.docx 6 How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs Non-technical questions about this job should be addressed to the recruiting department directly: hr@ndorms.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. 172013 Project Manager_JD.docx 7 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacypolicy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/dataprotection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 172013 Project Manager_JD.docx 8 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. 172013 Project Manager_JD.docx 9
We have an exciting opportunity for a Research Assistant in Health Data Sciences to join the Pharmaco- and Device epidemiology research group led by Professor Daniel Prieto-Alhambra at the Botnar Research Centre, NDORMS, University of Oxford. The NDORMS Pharmaco- and Device epidemiology research group is involved in a number of national and international studies exploring the conditions of use (adherence, compliance, off and on-label use) of a number of licensed drugs, devices, and vaccines for the prevention and treatment of human disease in 'real world' (routine practice) conditions. As a Research Assistant in Health Data Sciences you will contribute to the programming of analytical pipelines for the analysis of routinely collected data mapped to the OMOP Common Data Model. You will analyse real world data to address regulatory questions related to the prevalence/incidence of disease, use of medicines/vaccines, and the risks or benefits of medicines/vaccines or devices. You will prepare analytical packages to run a number of pre-specified analyses, contribute to wider project planning, including ideas for new research projects and gather, analyse, and present scientific data from a variety of sources. You will hold a relevant BA or MSc degree in Mathematics, Engineering, or a related field. Knowledge of medical statistics and experience analysing large datasets, experience in biostatistics and/or health data sciences and experience in the programming of R packages are essential. Experience in propensity scores, overlap weighting, inverse probability weighting and/or similar methods, expertise in pharmaco or vaccine epidemiology and experience of working with electronic medical records/routinely collected data are desirable. This is a full-time fixed-term appointment for 2 years. The closing date for this position is 12 noon on 10 May 2024. You will be required to upload a CV and supporting statement as part of your online application.
This role can be offered as a secondment opportunity. The purpose of this role is to contribute to the successful running of the growing portfolio of Experimental Medicine studies involving human immune challenge being conducted in Oxford and led by A/Prof James Fullerton Associate Professor of Clinical Therapeutics, NDORMS, University of Oxford which is based at the Botnar Research Centre. These tend to involve healthy volunteers, be of small size (<50 participants) and will largely be conducted at a single site. As the Project Manager, reporting directly to Professor Fullerton, the post holder will take responsibility for the coordination of all areas of trial operationalisation including site set up, data management and site closure activities. The post holder will utilise their clinical trials experience and knowledge to provide administrative and technical support to Professor Fullerton’s group. It is anticipated the post holder will also contribute to protocol development, obtaining relevant ethical and regulatory approvals, as well as directly contributing to day-to-day operational issues including screening and scheduling participants study visits. The post holder will be expected to work independently with minimal supervision across a number of studies within the group, adapting to current demands. It is hoped the post holder will eventually contribute to overall strategic and operational leadership of the group. You will hold a degree in at least BSc level or equivalent qualifications/experience, with demonstrable experience in trial coordination/administration/support role. You will have experience of knowledge of UK clinical research structures, regulatory and ethical systems, and experience of working to a high standard of Good Clinical Practice. The ability to work independently and problem solve. You will have demonstrate an understanding of data protection and other statutory requirements and professional guidelines, such as Good Clinical Practice guidelines This is a full-time fixed-term maternity cover appointment for 6 months or the actual return of the substantive postholder, or the resignation of the substantive postholder and employment of a new postholder, whichever is the earliest. This role is available from 27/05/2024. The closing date for this position is 12 noon on 30 April 2024. You will be required to upload a CV and supporting statement as part of your online application.
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Job Description _________________________________________________________________________ Summary Job title Postdoctoral Health Data Scientist Division Medical Sciences Division Department Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Location Botnar Research Centre, Windmill Road, Oxford, OX3 7LD Grade and salary Grade 7: £36,024- £38,205 per annum Hours Full time Contract type Fixed-term for 21 months Reporting to Associate Professor Sara Khalid Vacancy reference 172572 Additional information A lower grade offer may be made (Grade 6: £32,332- £38,205 p.a.) with commensurate reduction in responsibilities (and a change in job title to Research Assistant) if a suitable candidate cannot be found to fill the Grade 7 position. The role Project details Welcome to the Planetary Health Informatics Group. We combine fair and safe artificial intelligence, remote monitoring technology and clinical epidemiology to study international real-world health, environment, and climate data, for the prevention and treatment of human diseases and to fill the gaps in global health, leveraging common data models and federated network analytics. We work closely with clinicians, engineers, epidemiologists, conservationists, data scientists, policy-makers, and public and patient groups in the UK and from around the world to co-create models for equitable and ethical solutions for planetary health problems in everyday (“routine”) settings. We study benefits and risks of health technologies particularly in special subgroups of the population who may have rare conditions or may otherwise be under-represented in clinical trials, those disproportionately affected by health inequities, and those most climate vulnerable. Additionally, we are also interested in fair and safe use of AI technology e.g. large language models and foundation models for under-resourced settings around the world. You can learn more about our research and teaching at https://www.ndorms.ox.ac.uk/research/researchgroups/planetary-health-informatics The clinical application domain ranges from communicable and chronic conditions through to multi-morbidity. There are ongoing studies in our current work to support each of these areas of research through local, national and international collaborations such as with Health Data Research UK, British Heart Foundation, Bill & Melinda Gates Foundation, Innovative Medicines Initiative, pharma industry and others. These and similar studies will become part of your research portfolio. Overview of the role As a Postdoctoral Health Data Scientist, you will have responsibility for: 1. Supporting research projects from inception to reporting and dissemination/publication. 2. Analysis and interpretation of routinely collected datasets both nationally and internationally as part of ongoing and future research projects. 3. Supervision of or providing support to student/s within the research group. 4. Contributing to writing research grants within the group’s remit to obtain funding from both competitive and non-competitive (i.e. industry or similar) sources. 5. Represent the group in international collaboration/s and related meeting/s. Responsibilities 1. 2. 3. 4. 5. 6. 7. 8. To develop analysis plans, protocols, ethical (and similar panel) submissions, standard operating procedures, governance and regulatory submissions as required for ongoing and future studies. To analyse data following pre-specified analysis plan/s and/or approved protocols. To generate and analyse real world health data assets. To contribute to the programming of R/Python packages for the analysis of international network studies. To report research findings in the form of conference abstracts at national and international conferences. To lead and/or support the drafting of scientific manuscripts, reports to funders and other materials for other audiences based on the results from research studies. Manage own academic research and administrative activities. This involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines Adapt existing and develop new research methodologies and materials 169888 JD.docx 2 9. 10. 11. 12. 13. 14. 15. Prepare working theories and analyse qualitative and/or quantitative data from a variety of sources, reviewing and refining theories as appropriate Contribute ideas for new research projects Present papers at conferences or public meetings Act as a source of information and advice to other members of the group on methodologies or procedures Represent the research group at external meetings/seminars, either with other members of the group or alone Carry out collaborative projects with colleagues in partner institutions, and research groups To be involved in teaching and supervision of students. The job description is not intended to be rigid or inflexible and may include other duties and responsibilities commensurate with the grade of the post, as may be determined and directed by the line manager. You will be expected to work flexibly and respond positively to changing needs. Selection criteria Essential selection criteria 1. Have a Doctoral (or be near completion) or MSc degree in applied/medical statistics, bio/medical engineering, health data sciences, health informatics, computer science, clinical artificial intelligence, clinical/environmental epidemiology, or a similar field. 2. Experience working in academia 3. Demonstrable advanced skills and expertise in R programming 4. Demonstrable advanced skills in programming in Python, SQL, or similar languages 5. Ability to work within multi-disciplinary teams and independently 6. Self-motivated with good organization and time management skills 7. Ability to prioritize workload and write reports to a tight deadline 8. Ability to communicate results effectively in writing and verbally with colleagues in any discipline 9. Flexibility to learn new skills 10. Attention to detail Desirable selection criteria 1. Good track record of peer reviewed scientific publications 2. Experience of postgraduate teaching in the academic sector 3. Experience presenting at international conferences 4. Experience designing and conducting cohort, case-control, and similar studies 5. Experience in the analysis/es of routinely collected (aka ‘real world’) health data 6. Experience in prediction modelling 7. Experience in medical large language models and foundation models 8. Experience in propensity score/s, instrumental variable/s, and/or other methods to adjust for confounding in observational studies 9. Experience in common data models 169888 JD.docx 3 10. Ability to communicate in additional languages (in addition to English) 11. Willingness to travel both within the United Kingdom and abroad to conduct research and attend conferences and research meetings 12. Experience of writing reports for research sponsors/funders, and manuscripts for peer reviewed journal submission Please note that the appointment of the successful candidate will be subject to standard compulsory preemployment screening, such as right to work checks. Please click here to read the candidate notes on the University’s pre-employment screening procedures. Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks 169888 JD.docx 4 About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognised centre of excellence for biomedical and clinical research and teaching. We are the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: www.medsci.ox.ac.uk Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching. Our mission is to discover the causes of musculoskeletal and inflammatory conditions to deliver excellent and innovative care that improves people’s quality of life. Our highly skilled teams have expertise in a broad range of areas, including orthopaedic surgery, inflammation, immunology, rheumatology, medical statistics, epidemiology, and clinical trials. We currently have 480 staff, approximately 120 post-graduate students and have a grant portfolio worth over £180 million. 169888 JD.docx 5 The Botnar Research Centre enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research. It takes a multidisciplinary approach, encompassing orthopaedic, rehabilitation and rheumatology clinical scientists, bone oncologists, laboratory scientists, epidemiologists, engineers and statisticians. The Botnar also hosts the Oxford Clinical Trials Research Unit (OCTRU) and the Centre of Statistics in Medicine (CSM), providing excellent statistical support to all aspects of clinical research. The Botnar opened in 2002, with a large annex completed in 2013. The Botnar is now home to around 300 staff and postgraduate students enjoying the international and friendly atmosphere of this workplace and benefits from the vast knowledge of leading experts in the field of musculoskeletal research. To accommodate its rapid growth, the Centre has opened another wing in early 2022. The new space provides additional 1000m2 of office and 1000m2 of laboratory space. The laboratory space includes a GMP clean room facility suitable for the manufacturing of biomaterials for human implantation. Sharing the site of the Nuffield Orthopaedic Centre, the largest specialist academic musculoskeletal hospital in the UK, puts the Botnar in a unique position to foster the collaboration between basic scientists and clinicians, which is essential to success in medical research. The Kennedy Institute is a biomedical research centre uniquely bringing together discovery science and earlystage clinical research, to develop transformative new therapies for chronic inflammatory and musculoskeletal conditions. Broadly focused on the thematic areas of immunity and microbiome, inflammation biology and tissue remodelling and repair, the Institute’s research is relevant for a range of common diseases such as arthritis, inflammatory bowel disease, fibrosis and cancer. The Institute has capacity for up to 260 staff and students who work collaboratively across 25 research groups. This enables a multidisciplinary approach of molecular and cellular biology, combined with analysis of disease models, patient tissue samples and longitudinal clinical data. Collectively, these studies seek to uncover the biological processes that maintain tissue health and how these pathways break down in disease. Research at the Institute is supported by a suite of core technology platforms, as well as through strategic partnerships with other basic and clinical research centres in Oxford, across the UK and internationally. These state-of-the-art technologies include the Oxford-Zeiss Centre for Excellence and other advanced microscopy and imaging facilities, mass and flow cytometry, as well as capabilities for microbial genomics and functional microbiome studies made available through the Oxford Centre for Microbiome Studies. Complementing a strong programme of lab-based research, the Institute has established a core of expertise and technologies in data science including single cell genomics, statistical genetics, computational biology, and research informatics. A recent extension to the Institute building with a new third floor creates additional space purposely designed for computationally intensive research. A true trendsetter in innovative and transformational research, the Kennedy also boasts a relaxed and friendly atmosphere, revolving around its bright and airy atrium that provides a space for colleagues to meet over coffee and tea to talk about their research and beyond throughout the day. 169888 JD.docx 6 For more information please visit: http://www.kennedy.ox.ac.uk Centre for Statistics in Medicine The Centre for Statistics in Medicine (CSM) (Director: Professor Gary Collins) in Oxford is committed to providing collaborative statistical support for the design, analysis and reporting of clinical research, carries out a methodological research programme and runs training courses. One of several teams within CSM, the OCTRU Statistics Team collaborates in clinical trials and other research within the University, with local and regional NHS trusts and with academic and charitable organisations throughout the UK. Our current portfolio includes 50 local, national and international trials. The CSM also has 5 statisticians working primarily on a programme of methodological research relating to studies of prognosis; a team of Biomedical Research Centre (BRC) funded statisticians; hosts the EQUATOR initiative; and carries out a programme of work aiming at improving the reporting of health research. Members of all groups within the CSM participate in occasional training activities. Further details of the activities of the wider CSM can be found here: https://www.csm.ox.ac.uk/ 169888 JD.docx 7 Athena Swan The Athena SWAN Awards specifically recognise success in developing employment practices to further and support the careers of women in science, technology, engineering, maths and medicine (STEMM) departments in academia. In May 2015 the charter was expanded to recognise work undertaken in arts, humanities, social sciences, business and law (AHSSBL), and in professional and support roles. Within NDORMS, we feel that we have an established culture of equality but are using the process to spur on-going improvement that benefits everyone involved in the Department. Our on-going progress was rewarded in May 2014 with an Athena Swan Bronze Award and in October 2015 with a Silver Award. Our development in this area has resulted in a number of commitments to our staff, central to which are: ➢ establishing an open, supportive and family-friendly research environment ➢ supporting career progression through teaching programmes, personal development reviews and mentoring ➢ proactive communication of support policies such as flexible working, provision of leave, promotion and career support schemes NDORMS aims to actively promote the implementation of the University’s family-friendly policies to help foster a family friendly working environment, including provision of family leave (such as policies for maternity, paternity, parental, carers and adoption leave), flexible/part-time working and scheduling inclusive meetings. The University’s childcare services support staff with a Childcare Voucher Scheme to help staff save tax and national insurance on childcare costs, offer information on nursery providers and a nursery fee Salary Sacrifice Scheme, work in partnership with playscheme providers to help support families during school holidays and signpost staff to parenting, local authority and other organisations that help support families and parents. The Department is also committed to ensuring that staff undertaking part-time or flexible working receive the same access to benefits and entitlements as full-time staff, including the same opportunities for training and promotion, a pro-rata entitlement to leave including bank holidays and careful consideration of requests to work part-time (particularly for those by staff returning from maternity leave). For more information please visit: http://www.admin.ox.ac.uk/personnel/staffinfo/benefits/family/ and http://www.admin.ox.ac.uk/personnel/during/flexible/ We are also actively working to uphold the University’s aim of providing an inclusive environment and equal career opportunities by promoting equality, valuing diversity and maintaining a working, learning and social environment in which the rights and dignity of all staff are respected. Separate University policies are also in place to ensure race, disability and gender equality. For more information, please visit: http://www.admin.ox.ac.uk/eop/ 169888 JD.docx 8 How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs Non-technical questions about this job should be addressed to the recruiting department directly HR@ndroms.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. 169888 JD.docx 9 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacypolicy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/dataprotection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 169888 JD.docx 10 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. 169888 JD.docx 11
We have an exciting opportunity for a Postdoctoral Health Data Scientist to join the research group led by Associate Professor Sara Khalid at the Centre for Statistics in Medicine, the Botnar Research Centre, NDORMS, University of Oxford. Welcome to the Planetary Health Informatics Group. We combine fair and safe artificial intelligence, remote monitoring technology and clinical epidemiology to study international real-world health, environment, and climate data, for the prevention and treatment of human diseases and to fill the gaps in global health, leveraging common data models and federated network analytics. As a Postdoctoral Data Scientist, you will develop analysis plans, protocols, ethical (and similar panel) submissions, governance and regulatory submissions as required for ongoing and future studies. You will generate and analyse real world health data assets, analyse data following pre-specified analysis plans and/or approved protocols and prepare working theories and analyse quantitative data from a variety of sources, reviewing and refining theories as appropriate. You will carry out collaborative projects with colleagues in partner institutions, and research groups, present papers at conferences or public meetings, lead and support the drafting of scientific manuscripts for dissemination as well as manage your own academic research and administrative activities. You will hold a Doctoral (or be near completion) or MSc degree in applied/medical statistics, bio/medical engineering, health data sciences, health informatics, computer science, clinical/environmental epidemiology, or a similar field. Demonstrable advanced skills in programming in Python, SQL, or similar languages, advanced skills and expertise in R programming and to communicate results effectively in writing and verbally with colleagues in any discipline are essential. Experience designing and conducting cohort, case- control, and similar studies, experience in prediction modelling and experience in common data models are desirable. This is a full-time post, fixed-term contract for 21 months. A lower grade offer may be made (Grade 6: £32,332- £33,205 p.a.) with commensurate reduction in responsibilities (and a change in job title to Research Assistant in Health Data Sciences) if a suitable candidate cannot be found to fill the Grade 7 position. The closing date for applications is 12 noon on 08/05/2024. You will be required to upload a supporting statement as part of your online application. Please quote 172572 on all correspondence.
The Kennedy Institute at the University of Oxford has an exciting opening for an experienced bioinformatician to join the group of Associate Professor Stephen Sansom (https://sansomlab.org). In this core-funded role you will lead the development of pipelines and tools for the analysis of data from cutting-edge single cell and spatial genomics platforms such as the 10x Chromium and Nanostring CosMx. You will have the opportunity to work with students and postdocs from the Kennedy’s world-leading research groups both to provide bioinformatics training and to make contributions to publications in high impact journals. Researchers at the KIR are using cutting-edge approaches to investigate the immune system and the cellular causes of diseases such as atheroschlerosis, inflammatory bowel disease and arthritis (https://www.kennedy.ox.ac.uk/research/research-groups). You should have an established track record of code development and contributions to publications or submitted manuscripts in peer-reviewed journals that demonstrates your bioinformatics expertise. A PhD/DPhil (or near completion) in a discipline of direct relevant to bioinformatics and genomic research is essential. In this role, you will undertake code development, provide bioinformatics training and perform scientific research developing and acquiring relevant skills as necessary. You will share code with the bioinformatics community, publishing tools and results in peer-reviewed journals. A good understanding of single-cell/spatial genomics data analysis is essential. The successful applicant will be based at the Kennedy Institute of Rheumatology within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences. The closing date for this position is 12 noon on Friday 3 May 2024. Please read the accompanying job description carefully and ensure that you address each selection criteria in a supporting statement which must be uploaded together with your CV when applying online. For further information please contact Associate Professor Stephen Sansom: stephen.sansom@kennedy.ox.ac.uk or Prof Irina Udalova: irina.udalova@kennedy.ox.ac.uk. This core-funded post will be initially appointed as a fixed-term, full time position until 31/07/2026.
Standard Grade 6: £32,332 - £38,205 p.a. (pro rata)
Postdoctoral Research Associate in Bioinformatics
_________________________________________________________________________ Summary Job title Postdoctoral Research Associate in Bioinformatics Division Medical Sciences Division Department Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Location Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3 7FY Grade and salary Grade 8: £45,585 - £51,283 per annum Hours Full time Contract type Fixed-term until 31/07/2026 Reporting to Associate Professor Stephen Sansom Vacancy reference 172445 Additional information A lower grade offer (Grade 7: £36,024 - £ 48,350 p.a.) may be made to a less experienced candidate (such as recent PhD/DPhil graduates) if a suitable candidate cannot be found to fill the Grade 8 position. Research topic Bioinformatic analysis of single-cell and spatial genomics data Principal Investigator / supervisor Associate Professor Stephen Sansom Project team Computational and Single Cell Genomics Project web site https://www.kennedy.ox.ac.uk/research/computational-genomics Funding partner The funds supporting this research project are provided by the Kennedy Trust for Rheumatology Research. Recent publications (1) Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury. Cross et al., JCI Insight 2023. (2) Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites. Maclean et al. Immunity. 2022. (3) A blood atlas of COVID-19 defines hallmarks of disease severity and specificity. COMBAT Consortium. Cell 2022. (4) IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies. Friedrich et al., Nature Medicine 2021 (5) Distinct fibroblast subsets drive inflammation and damage in arthritis. Croft, A. et al. Nature. 2019. (6) Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance. Aschenbrenner et al., Gut 2020 (7) IRF5 guides monocytes toward an inflammatory CD11c+ macrophage phenotype and promotes intestinal inflammation. Corbin et al. Science Immunology 2020. The role Research context The Kennedy Institute of Rheumatology (KIR) is a world-class academic research centre at the University of Oxford. It has a mission to understand and develop therapies for inflammatory diseases such as atherosclerosis, arthritis, and inflammatory bowel disease. Our researchers are using multi-modal single-cell and spatial transcriptomics approaches to study the immune system and investigate the cellular causes of immune-mediated inflammatory diseases (https://www.kennedy.ox.ac.uk/platforms-and-technologies/single-cell-and-spatialgenomics). This work includes studies of clinical cohorts, functional analysis of model organisms and participation in community projects such as the Human Cell Atlas (https://www.humancellatlas.org/) project. The institute has a vibrant and growing data science community with established groups specialising in single cell genomics (Associate Professor Stephen Sansom), microbiome analysis (Dr Jethro Johnson), statistical method development (Dr Yang Luo) and statistical genetics (Dr Luke Jostins-Dean). It has close links with the Big Data Institute, Wellcome Centre for Human Genetics and Institute for Developmental and Regenerative Medicine which are located next-door on the Old Road Campus. Role overview As a post-doc in the group of Associate Professor Stephen Sansom (https://sansomlab.org) you will lead the development of bioinformatics pipelines and tools for single-cell and spatial genomics datasets (see e.g. https://cellhub.readthedocs.io) and provide bioinformatics help and training to KIR students and staff. You will also participate in collaborative research projects 2 with other KIR groups, contributing to publications in high impact peer-reviewed journals. This is a core-funded position. Responsibilities Key responsibilities            To write and maintain open-source bioinformatic pipelines and tools for singlecell and spatial data analysis. To provide bioinformatics training and supervision to KIR students and staff. To help run the KIR Genomics Training Forum. To participate in collaborative projects with KIR groups. To help write, prepare and publish tools and analysis results in peer-reviewed national and international journals. To present your work in regular meetings, by poster and oral presentations at national and international scientific meetings, and via other suitable means. To identify training needs and to follow an agreed strategy to achieve them. To keep abreast of the relevant literature and methodological developments and to contribute ideas for new research projects. To manage your code development, training and project activities. This will involve agreeing clear task objectives, organising, and delegating work as appropriate to meet deadlines. To help raise research funds through grant applications, and to manage your own area of a larger research budget. To regularly version control and share code with the community using github, and to keep accurate, up-date and accessible records of project work. Relationships   The post-doctoral Research Associate will be a member of the Computational and Single Cell Genomics team led by Associate Professor Stephen Sansom (http://sansomlab.org). The post-hold will have the opportunity to work with other bioinformatics groups at the KIR and more widely at the University of Oxford. Selection criteria Essential selection criteria  To hold a PhD/DPhil (or near completion) in a discipline of direct relevance to computational single cell and spatial genomics bioinformatics research, or equivalent experience.  Strong and demonstrable competence with the programming languages Python and R, and with the writing of bioinformatics pipelines. 3  Computational genomics code development experience that includes the documentation and version control of source code.  Good working knowledge and understanding of single cell genomics and/or spatial transcriptomics data analysis approaches.  Experience providing data science skills training or project supervision to fellow researchers or students.  Hands-on experience with the computational analysis of genomic data sets evidenced by contributions to publications or submitted manuscripts in peerreviewed journals.  Excellent interpersonal skills, able to work independently and collaboratively with experimental and clinical colleagues.  Highly motivated and able to use own initiative to solve problems.  Excellent communication skills, evidenced for oral presentations, documentation of code and written contributions to scientific manuscripts.  Demonstrate an ability to follow departmental guidance in handling sensitive and personal information, including complying with current data protection legislation. Desirable selection criteria  A track record of contributions to open-source community bioinformatics code projects (such as e.g. Bioconductor).  Experience of presenting work at meetings.  Cross-disciplinary collaborative experience. Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Additional security pre-employment checks 4 Due to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks:  A satisfactory basic Disclosure and Barring Service check About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognised centre of excellence for biomedical and clinical research and teaching. We are the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: www.medsci.ox.ac.uk 5 Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching. Our mission is to discover the causes of musculoskeletal and inflammatory conditions to deliver excellent and innovative care that improves people’s quality of life. Our highly skilled teams have expertise in a broad range of areas, including orthopaedic surgery, inflammation, immunology, rheumatology, medical statistics, epidemiology, and clinical trials. We currently have 460 staff, 100 students and have a grants portfolio worth over £148 million, and an annual turnover in excess of £38 million. The Kennedy Institute is a biomedical research centre uniquely bringing together discovery science and earlystage clinical research, to develop transformative new therapies for chronic inflammatory and musculoskeletal conditions. Broadly focused on the thematic areas of immunity and microbiome, inflammation biology and tissue remodelling and repair, the Institute’s research is relevant for a range of common diseases such as arthritis, inflammatory bowel disease, fibrosis and cancer. The Institute has capacity for up to 260 staff and students who work collaboratively across 25 research groups. This enables a multidisciplinary approach of molecular and cellular biology, combined with analysis of disease models, patient tissue samples and longitudinal clinical data. Collectively, these studies seek to uncover the biological processes that maintain tissue health and how these pathways break down in disease. Research at the Institute is supported by a suite of core technology platforms, as well as through strategic partnerships with other basic and clinical research centres in Oxford, across the UK and internationally. These state-of-the-art technologies include the Oxford-Zeiss Centre for Excellence and other advanced microscopy and imaging facilities, mass and flow cytometry, as well as capabilities for microbial genomics and functional microbiome studies made available through the Oxford Centre for Microbiome Studies. Complementing a strong programme of lab-based research, the Institute has established a core of expertise and technologies in data science including single cell genomics, statistical genetics, computational biology, and research informatics. A recent extension to the Institute building with a new third floor creates additional space purposely designed for computationally intensive research. A true trendsetter in innovative and transformational research, the Kennedy also boasts a relaxed and friendly atmosphere, revolving around its bright and airy atrium that provides a space for colleagues to meet over coffee and tea to talk about their research and beyond throughout the day. For more information please visit: http://www.kennedy.ox.ac.uk 6 The Botnar Research Centre enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research. It takes a multidisciplinary approach, encompassing orthopaedic, rehabilitation and rheumatology clinical scientists, bone oncologists, laboratory scientists, epidemiologists, engineers and statisticians. The Botnar also hosts the Oxford Clinical Trials Research Unit (OCTRU) and the Centre of Statistics in Medicine (CSM), providing excellent statistical support to all aspects of clinical research. The Botnar opened in 2002, with a large annex completed in 2013. The Botnar is now home to around 300 staff and postgraduate students enjoying the international and friendly atmosphere of this workplace and benefits from the vast knowledge of leading experts in the field of musculoskeletal research. To accommodate its rapid growth, the Centre has opened another wing in early 2022. The new space provides additional 1000m2 of office and 1000m2 of laboratory space. The laboratory space includes a GMP clean room facility suitable for the manufacturing of biomaterials for human implantation. Sharing the site of the Nuffield Orthopaedic Centre, the largest specialist academic musculoskeletal hospital in the UK, puts the Botnar in a unique position to foster the collaboration between basic scientists and clinicians, which is essential to success in medical research. 7 Athena Swan The Athena SWAN Awards specifically recognise success in developing employment practices to further and support the careers of women in science, technology, engineering, maths and medicine (STEMM) departments in academia. In May 2015 the charter was expanded to recognise work undertaken in arts, humanities, social sciences, business and law (AHSSBL), and in professional and support roles. Within NDORMS, we feel that we have an established culture of equality but are using the process to spur on-going improvement that benefits everyone involved in the Department. Our on-going progress was rewarded in May 2014 with an Athena Swan Bronze Award and in October 2015 with a Silver Award. Our development in this area has resulted in a number of commitments to our staff, central to which are:  establishing an open, supportive and family-friendly research environment  supporting career progression through teaching programmes, personal development reviews and mentoring  proactive communication of support policies such as flexible working, provision of leave, promotion and career support schemes NDORMS aims to actively promote the implementation of the University’s family-friendly policies to help foster a family friendly working environment, including provision of family leave (such as policies for maternity, paternity, parental, carers and adoption leave), flexible/part-time working and scheduling inclusive meetings. The University’s childcare services support staff with a Childcare Voucher Scheme to help staff save tax and national insurance on childcare costs, offer information on nursery providers and a nursery fee Salary Sacrifice Scheme, work in partnership with playscheme providers to help support families during school holidays and signpost staff to parenting, local authority and other organisations that help support families and parents. The Department is also committed to ensuring that staff undertaking part-time or flexible working receive the same access to benefits and entitlements as full-time staff, including the same opportunities for training and promotion, a pro-rata entitlement to leave including bank holidays and careful consideration of requests to work part-time (particularly for those by staff returning from maternity leave). 8 For more information please visit: http://www.admin.ox.ac.uk/personnel/staffinfo/benefits/family/ and http://www.admin.ox.ac.uk/personnel/during/flexible/ We are also actively working to uphold the University’s aim of providing an inclusive environment and equal career opportunities by promoting equality, valuing diversity and maintaining a working, learning and social environment in which the rights and dignity of all staff are respected. Separate University policies are also in place to ensure race, disability and gender equality. For more information, please visit: http://www.admin.ox.ac.uk/eop/ 9 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Help and support is available from: https://hrsystems.admin.ox.ac.uk/recruitment-support If you require any further assistance please email recruitment.support@admin.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our e-recruitment system to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. 10 Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for all academic posts and some academic-related posts. The University has adopted an EJRA of 30 September before the 69th birthday for all academic and academic-related staff in posts at grade 8 and above. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra For existing employees, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra There is no normal or fixed age at which staff in posts at grades 1–7 have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 11 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to My Family Care, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare. The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. 12
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Research Assistant in Health Data Sciences
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We have an exciting opportunity for a Research Nurse to join our small, friendly research team, working under the supervision of Mrs Gail Lang at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences at the Nuffield Orthopaedic Centre, Oxford. As Research Nurse you will work within a multi-disciplinary setting between rheumatology, orthopaedics and physiotherapy. You will identify potential study participants and work with clinical teams in inpatient and outpatient settings to recruit eligible patients for musculoskeletal studies. You may on occasion be expected to travel to other OUHFT hospitals. Responsibilities will include; reviewing NHS case records, ensuring patient suitability according to study entry criteria, recording of study related information, obtaining informed consent to participate in specific studies, and ensuring the safe administration of treatments and drugs in line with the study protocols. You will also perform clinical procedures including venepuncture, height and weight measurements, history taking and study specific examinations and with training if required, ensuring the safe handling and quality of the labelling, processing and storage of biological samples. You will be an NMC Registered Nurse with experience demonstrating the appropriate competencies and skills for the role. You will have good computing skills including Microsoft Word, and the ability to manage your time well and work using your own initiative. Experience of working within a secondary care environment and a full UK driving licence are desirable. This is a part-time appointment (0.6 FTE, 22.5 hours per week) for 12 months in the first instance. This job includes the following duties which will require additional security pre-employment checks: • A satisfactory enhanced Disclosure and Barring Service check due to regulated activity involving children or ‘at risk’ adults. A lower grade offer may be made (Grade 5: £28,759 – £37,099 pro rata, p.a.) with commensurate reduction in responsibilities if a suitable candidate cannot be found to fill the Grade 6 position. The closing date for this position is **12:00 noon on Friday 03 May 2024**. You will be required to upload a supporting statement and CV as part of your online application.
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Research Assistant in Epidemiology and Health Data Sciences
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172445 KTRR Bioinformatics PDRA JD FINAL.pdf
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_________________________________________________________________________ Summary Job title Research Nurse (Part Time) Division Medical Sciences Division Department Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences Location Nuffield Orthopaedic Centre, Windmill Road, Oxford, OX3 7HE Grade and salary Grade 6: £32,332 - £38,205 pro rata, per annum Hours Part time (0.6 FTE) Contract type Fixed-term for 12 months in the first instance Reporting to Gail Lang, Research Manager Vacancy reference 171225 Additional information A lower grade offer may be considered (Grade 5: £28,759 – £37,099 per annum) depending on experience, with commensurate reduction in responsibilities. The role The post, based at the Nuffield Orthopaedic Centre, Oxford, is designed to provide nursing support for an evolving range of musculoskeletal research studies which are adopted by the National Institute for Health Research portfolio. The role involves the screening, assessment, coordination, and recruitment of patients into clinical studies. The post will be flexible, working in a team of research nurses and other healthcare professionals based at the NOC with the occasional possibility of visiting other OUH Foundation Trust hospitals. Studies to be supported include orthopaedic surgical interventional and observational studies and studies in rheumatology. The post is funded for a one year period in the first instance. Responsibilities 1. The post will be based at the Nuffield Orthopaedic Centre (NOC), but the successful applicant may on occasion be expected to travel to other OUHFT hospitals. 2. Training will be provided in the skills necessary to undertake the research, as part of the post. 3. The applicant will liaise with the research manager and study co-ordinator for each study, to ensure the most efficient recruitment of patients. 4. It is anticipated that the applicant will support new studies or existing studies and supported by Gail Lang, according to the required workload. 5. The applicant will need to work flexibly in the team to make best use of their time. 6. Clinical procedures include venepuncture; height and weight measures, history taking and study specific examinations; and ensuring that the labelling, processing and storage of biological samples meets the necessary requirements of the research protocol in order to make certain that safe handling and quality is assured. 7. The role includes collating data, reviewing NHS case records and ensuring patient suitability according to study entry criteria. 8. Maintaining effective communication with research subjects and other members of the multidisciplinary/research team. 9. Providing ongoing advice and information to subjects, and where indicated in a protocol, obtain informed consent on behalf of the Chief Investigator or Principle Investigator of each study, in order to facilitate effective informed consent. 10. Awareness and understanding of the up to date protocol and SOPs. 11. Maintenance of study records in accordance with Good Clinical Practice (GCP). 12. Administrative duties: to ensure smooth and efficient running of the studies. Selection criteria Essential selection criteria • • • • • • • • • • • Registered Nurse with relevant post registration experience Relevant experience demonstrating the appropriate competencies and skills for the role Evidence of team working skills The ability to work using own initiative Effective listening and interpersonal skills Time management skills/ability to prioritise workload. Good computing skills including Microsoft Word Good command of written and spoken English evidenced by ability to explain and interpret procedures clearly Willingness to travel to other sites if required Demonstrate an ability to follow departmental guidance in handling sensitive and personal information, including complying with current data protection legislation Demonstrate an understanding of data protection and other statutory requirements and professional guidelines, such as ICH Good Clinical Practice guidelines Desirable selection criteria • Experience of working within a hospital environment nursing patients who have inflammatory, musculoskeletal, bone and joint diseases 2 • • • Venepuncture competency A full UK Driving Licence Clinical Research experience Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • Lone Working • Driving on University business • Regular manual handling • Working with blood, human products and human tissues • Work in clinical areas with direct contact with patients (NOT administrative roles) Additional security pre-employment checks This job includes duties that will require additional security pre-employment checks: • A satisfactory enhanced Disclosure and Barring Service check due to regulated activity involving children OR regulated activity involving ‘at risk’ adults 3 About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognised centre of excellence for biomedical and clinical research and teaching. We are the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information please visit: www.medsci.ox.ac.uk Musculoskeletal Thames Valley and South Midlands Clinical Research Network The NIHR Musculoskeletal Thames Valley and South Midlands CRN is a combined musculoskeletal collaboration from the rheumatology, orthopaedic and physiotherapy research teams at Oxford University Hospitals NHS Foundation Trust and the University of Oxford which enables sharing of resources across specialties and studies. All the studies in our musculoskeletal portfolio are recruiting patients or about to recruit patients; most are multicentre externally funded studies. In the year 2018/2019 over 1000 patients were recruited into MSK portfolio studies. The post-holder will be working within a team of research nurses study and tissue co-ordinators working on other similar NIHR portfolio studies. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching. Our mission is to discover the causes of musculoskeletal and inflammatory conditions to deliver excellent and innovative care that improves people’s quality of life. Our highly skilled teams have expertise in a broad range of areas, including orthopaedic surgery, inflammation, immunology, rheumatology, medical statistics, epidemiology, and clinical trials. 4 We currently have 480 staff, approximately 120 post-graduate students and have a grant portfolio worth over £180 million. The Botnar Research Centre enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research. It takes a multidisciplinary approach, encompassing orthopaedic, rehabilitation and rheumatology clinical scientists, bone oncologists, laboratory scientists, epidemiologists, engineers and statisticians. The Botnar also hosts the Oxford Clinical Trials Research Unit (OCTRU) and the Centre of Statistics in Medicine (CSM), providing excellent statistical support to all aspects of clinical research. The Botnar opened in 2002, with a large annex completed in 2013. The Botnar is now home to around 300 staff and postgraduate students enjoying the international and friendly atmosphere of this workplace and benefits from the vast knowledge of leading experts in the field of musculoskeletal research. To accommodate its rapid growth, the Centre has opened another wing in early 2022. The new space provides additional 1000m2 of office and 1000m2 of laboratory space. The laboratory space includes a GMP clean room facility suitable for the manufacturing of biomaterials for human implantation. Sharing the site of the Nuffield Orthopaedic Centre, the largest specialist academic musculoskeletal hospital in the UK, puts the Botnar in a unique position to foster the collaboration between basic scientists and clinicians, which is essential to success in medical research. The Kennedy Institute is a biomedical research centre uniquely bringing together discovery science and earlystage clinical research, to develop transformative new therapies for chronic inflammatory and musculoskeletal conditions. Broadly focused on the thematic areas of immunity and microbiome, inflammation biology and tissue remodelling and repair, the Institute’s research is relevant for a range of common diseases such as arthritis, inflammatory bowel disease, fibrosis and cancer. The Institute has capacity for up to 260 staff and students who work collaboratively across 25 research groups. This enables a multidisciplinary approach of molecular and cellular biology, combined with analysis of disease models, patient tissue samples and longitudinal clinical data. Collectively, these studies seek to uncover the biological processes that maintain tissue health and how these pathways break down in disease. Research at the Institute is supported by a suite of core technology platforms, as well as through strategic partnerships with other basic and clinical research centres in Oxford, across the UK and internationally. These state-of-the-art technologies include the Oxford-Zeiss Centre for Excellence and other advanced microscopy and imaging facilities, mass and flow cytometry, as well as capabilities for microbial genomics and functional microbiome studies made available through the Oxford Centre for Microbiome Studies. Complementing a strong programme of lab-based research, the Institute has established a core of expertise and technologies in data science including single cell genomics, statistical genetics, computational biology, and research informatics. A recent extension to the Institute building with a new third floor creates additional space purposely designed for computationally intensive research. 5 A true trendsetter in innovative and transformational research, the Kennedy also boasts a relaxed and friendly atmosphere, revolving around its bright and airy atrium that provides a space for colleagues to meet over coffee and tea to talk about their research and beyond throughout the day. For more information please visit: http://www.kennedy.ox.ac.uk Athena Swan The Athena SWAN Awards specifically recognise success in developing employment practices to further and support the careers of women in science, technology, engineering, maths and medicine (STEMM) departments in academia. In May 2015 the charter was expanded to recognise work undertaken in arts, humanities, social sciences, business and law (AHSSBL), and in professional and support roles. Within NDORMS, we feel that we have an established culture of equality but are using the process to spur on-going improvement that benefits everyone involved in the Department. Our on-going progress was rewarded in May 2014 with an Athena Swan Bronze Award and in October 2015 with a Silver Award. Our development in this area has resulted in a number of commitments to our staff, central to which are: ➢ establishing an open, supportive and family-friendly research environment ➢ supporting career progression through teaching programmes, personal development reviews and mentoring ➢ proactive communication of support policies such as flexible working, provision of leave, promotion and career support schemes NDORMS aims to actively promote the implementation of the University’s family-friendly policies to help foster a family friendly working environment, including provision of family leave (such as policies for maternity, paternity, parental, carers and adoption leave), flexible/part-time working and scheduling inclusive meetings. The University’s childcare services support staff with a Childcare Voucher Scheme to help staff save tax and national insurance on childcare costs, offer information on nursery providers and a nursery fee Salary Sacrifice Scheme, work in partnership with playscheme providers to help support families during school holidays and signpost staff to parenting, local authority and other organisations that help support families and parents. The Department is also committed to ensuring that staff undertaking part-time or flexible working receive the same access to benefits and entitlements as full-time staff, including the same opportunities for training and promotion, a pro-rata entitlement to leave including bank holidays and careful consideration of requests to work part-time (particularly for those by staff returning from maternity leave). For more information please visit: http://www.admin.ox.ac.uk/personnel/staffinfo/benefits/family/ and http://www.admin.ox.ac.uk/personnel/during/flexible/ We are also actively working to uphold the University’s aim of providing an inclusive environment and equal career opportunities by promoting equality, valuing diversity and maintaining a working, learning and social environment in which the rights and dignity of all staff are respected. Separate University policies are also in place to ensure race, disability and gender equality. For more information, please visit: http://www.admin.ox.ac.uk/eop/ 6 How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs Non-technical questions about this job should be addressed to the recruiting department directly, at HR@ndorms.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacypolicy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/dataprotection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. 7 There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 8 Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependents. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency back-up care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care Childcare The University has excellent childcare services, including five University nurseries as well as University-supported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. 9
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