Past vacancies at the University of Oxford
Henry Wellcome Building of Cellular and Molecular Physiology
Source
Job title Postdoctoral Research Assistant in Quantitative Spatial Data Analysis for Colorectal Precancer Division Medical Sciences Department Nuffield Department of Medicine Location Centre for Human Genetics, Building for Genomic Medicine, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7BN Grade and salary Research Grade 7: salary in range £38,674 - £46,913 p.a. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year Hours Full time Contract type Fixed-term contract until 31 December 2027 Funding is provided by GSK Reporting to Eoghan Mulholland, Spatial Biology Informatics Team Leader Vacancy reference 178283 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship under UK Visas and Immigration legislation. About us • • • What we offer https://hr.admin.ox.ac.uk/staff-benefits • An excellent contributory pension scheme • 38 days annual leave • A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata) • A comprehensive range of childcare services • Family leave schemes • Cycle loan scheme • Discounted bus travel and Season Ticket travel loans • Membership to a variety of social and sports clubs • A welcoming and diverse community Research topic Spatial Analysis of Spatial Transcriptomics for Colorectal Precancer Principal Investigator / supervisor PIs: Simon Leedham / Helen Byrne Project team GO-PRECISE team University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - https://www.chg.ox.ac.uk/ Co-Supervisors: Joshua Bull / Eoghan Mulholland Project web site https://www.chg.ox.ac.uk/people/simon-leedham https://www.maths.ox.ac.uk/people/helen.byrne Funding partner The funds supporting this research project are provided by GSK Recent publications EJM Mulholland et al (2024), bioRxiv 2024. 04.28.591245 JA Bull et al (2024), bioRxiv 2024.12.06.627195 JA Bull et al (2024), bioRxiv 2024.06.02.597010 BJ Stolz et al (2024). Bull Math Biol 86(11): 128. JA Bull et al (2024). Biological Imaging 4, e2. The role We invite applications for a Postdoctoral Research Assistant to work within the multidisciplinary GOPRECISE colorectal precancer team. This is a fixed term position until 31 December 2027, funded by GlaxoSmithKline (GSK). The work will be jointly supervised by Professor Simon Leedham (NDM), Professor Helen Byrne (Mathematical Institute, MI), Dr Joshua Bull (MI) and Dr Eoghan Mulholland (NDM). GlaxoSmithKline and Oxford University (GO) launched the PRECISE Alliance (Pre-Cancer Biology and Immunoprevention) in 2024, with the aim of conducting deep exploration of cancer precursors (precancers) to identify their molecular vulnerabilities and developing methods to intercept them. The alliance is directed by Professor Sarah Blagden. Within Oxford, the alliance spans multiple departments and brings together expertise in basic science (including spatial biology), immunology (including machine learning, bioinformatics, preclinical validation) and clinical development (including trial design, delivery and regulatory approval) as well as community engagement. This truly multi-disciplinary initiative aims to transform cancer by actively preventing its development, initially in people at highest risk of the disease and later in the wider population. This post is within the colorectal precancer theme which is jointly led by Simon Leedham and David Church. You will work as part of the Applied Spatial Biology Oxford group, a large multidisciplinary team of mathematicians, computational biologists, experimentalists and clinicians, and in collaboration with the research groups of Leedham and Byrne and the GO-PRECISE team. You will be responsible for developing and using cutting-edge mathematical methods to describe the spatial characteristics and cellular interactions that characterise colorectal precancer, identifying novel spatial biomarkers from spatial transcriptomics data, and exploring neoantigens or therapeutic targets that could be used for novel interception strategies. The generation of spatial data in biology has been transformed by multiplex imaging and spatial-omics technologies, such as single cell spatial transcriptomics. These approaches permit detailed mapping of phenotypic information about individual cells and their spatial locations within tissue sections. To aid in mathematical analysis of spatial data, you will use MuSpAn, a Python toolbox for multiscale analysis of spatial data which includes techniques drawn from spatial statistics, topological data analysis and networks (www.muspan.co.uk), to develop pipelines for high-throughput data analysis of spatial transcriptomics imaging. Your research will involve the theoretical development and practical application of new mathematical methods which expand this toolbox, using a new precancer dataset. 1 Responsibilities You will: • • • • • • • • • • Manage your own academic research and administrative activities. Adapt existing mathematical and statistical methods for analysis of high-dimensional imaging data, and develop new ones. Analyse quantitative imaging data from a variety of sources, including Spatial Transcriptomics and multiplex Spatial Proteomics platforms. Develop skills in computational biology and mathematical spatial analysis via independent study and training courses. Collaborate with colleagues from the Mathematical Institute, Centre for Human Genetics, and the PRECISE Alliance. Collaborate on the preparation of scientific reports and journal articles, present papers and posters at conferences/workshops. Follow and promote best practices for research software engineering and reproducible research within the University of Oxford and the wider UK and international research community. Contribute to community activities such as seminars and networking events. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Selection criteria Essential • • • • • • • • Hold a PhD/DPhil (or close to completion) in mathematics, statistics, physics, engineering, data science or a related discipline. Demonstrated ability to analyse and interpret complex multidimensional data. Experience of programming in Python, or demonstrated ability to rapidly acquire fluent knowledge of new programming languages, libraries, and platforms. Have a strong interest in interdisciplinary research in the biological and medical sciences. Excellent communication skills, including the ability to communicate effectively with biomedical researchers, write for publication and present research proposals and results, and represent the research group at meetings. Demonstrated enthusiasm for working across disciplinary boundaries. The ability to work independently and to pursue research as part of an interdisciplinary team. A good publication record, for your career stage. Desirable • • • • Experience of applying software engineering best practices (e.g. issue tracking, code review, testing, documentation and continuous integration) Experience of close collaboration with researchers in the biological or medical sciences. Experience of working with biomedical datasets, particularly cancer data and/or spatial data. Good organisational skills. 2 Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • • • Lone Working Regular manual handling Travel outside of Europe or North America on University Business 3 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents. • http://www.ox.ac.uk/about_the_university/jobs/research/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that: • • As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy 4 Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 5
Wellcome Trust Centre for Human Genetics
Research Grade 7: Research Grade 7: salary in range £38,674 - £46,913 p.a. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year
Subject
Nuffield Department of Clinical Medicine
**About the Role** The Peter Medawar Unit Administrator is an exciting opportunity for someone who is keen to work in a supporting role for a world leading research building, and who would be motivated by the opportunity to help find solutions so the building runs efficiently and effectively. A positive and flexible attitude is important, with a pro-active approach to the role. In addition, experience of administrative work in a university context and within the OUHT would be highly desirable. The administration team that supports the building is based on Level 5 of the John Radcliffe. This post will have close working relations with the team in order to ensure the administrative processes of the Building run smoothly. On a daily basis the Unit Administrator will liaise with the Chairman of the Building, the Laboratory Manager and the other members of the PMB management committee. **About You** To be considered for this position you should have; • Considerable experience of administrative and project management support for project delivery; • Excellent interpersonal skills, professional demeanour and a proactive and flexible approach to work; • High level of motivation with the ability to prioritise and drive your own work against deadlines while being respectful of other individuals responsibilities; • Evidence of knowledge in improvement schemes in Health Science, preferably with experience of compliance with government directives; • Website management skills; • Negotiation skills; • Ability to multitask including the ability to handle several complex assignments at once; **About the Nuffield Department of Clinical Medicine** The Nuffield Department of Clinical Medicine (NDM) is one of the largest departments of the University of Oxford and is part of the Medical Sciences Division, with responsibility for a significant part of the teaching of clinical students within the Medical School. **Benefits of working** University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits **Application Process** This position is available for up to three years in the first instance. Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Only applications received before 12:00 midday on Friday 23/05/2025 will be considered.
NDM Operations, Grant Management Team, based at the Li Ka Shing Centre for Health Information and Discovery, Old Road Campus, Heading, Oxford, OX3 7LF
Job title Postdoctoral Research Assistant in the Interpretation Transcriptomics and Proteomics for Colorectal Cancer Division Medical Sciences Department Nuffield Department of Medicine Location Centre for Human Genetics, Building for Genomic Medicine, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7BN Grade and salary Research Grade 7: salary in range £38,674 - £43,171 p.a. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year Hours Full time Contract type of Spatial Fixed-term contract until 31 December 2027 Funding is provided by GSK Reporting to Eoghan Mulholland, Spatial Biology Informatics Team Leader Vacancy reference 178278 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship under UK Visas and Immigration legislation. About us • • • What we offer https://hr.admin.ox.ac.uk/staff-benefits • An excellent contributory pension scheme • 38 days annual leave • A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata) • A comprehensive range of childcare services • Family leave schemes • Cycle loan scheme • Discounted bus travel and Season Ticket travel loans • Membership to a variety of social and sports clubs • A welcoming and diverse community Research topic Spatial Analysis and Interpretation of Spatial Transcriptomics for Colorectal Cancer Principal Investigator / supervisor PIs: Simon Leedham / Helen Byrne Co-Supervisors: Joshua Bull / Eoghan Mulholland Project team GO-PRECISE team Project web site https://www.chg.ox.ac.uk/people/simon-leedham https://www.maths.ox.ac.uk/people/helen.byrne University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - https://www.chg.ox.ac.uk/ Funding partner The funds supporting this research project are provided by GSK Recent publications EJM Mulholland et al (2024), bioRxiv 2024. 04.28.591245 JA Bull et al (2024), bioRxiv 2024.12.06.627195 JA Bull et al (2024), bioRxiv 2024.06.02.597010 BJ Stolz et al (2024). Bull Math Biol 86(11): 128. JA Bull et al (2024). Biological Imaging 4, e2. The role We invite applications for a Postdoctoral Research Assistant to work within the multidisciplinary GOPRECISE colorectal precancer team. This is a fixed term position until 31 December 2027, funded by GlaxoSmithKline (GSK). The work will be jointly supervised by Professor Simon Leedham (NDM), Professor Helen Byrne (Mathematical Institute, MI), Dr Joshua Bull (MI) and Dr Eoghan Mulholland (NDM). GlaxoSmithKline and Oxford University (GO) launched the PRECISE Alliance (Pre-Cancer Biology and Immunoprevention) in 2024, with the aim of conducting deep exploration of cancer precursors (precancers) to identify their molecular vulnerabilities and developing methods to intercept them. The alliance is directed by Professor Sarah Blagden. Within Oxford, the alliance spans multiple departments and brings together expertise in basic science (including spatial biology), immunology (including machine learning, bioinformatics, preclinical validation) and clinical development (including trial design, delivery and regulatory approval) as well as community engagement. This truly multi-disciplinary initiative aims to transform cancer by actively preventing its development, initially in people at highest risk of the disease and later in the wider population. This post is within the colorectal precancer theme which is jointly led by Simon Leedham and David Church. You will work as part of the Applied Spatial Biology Oxford group, a large multidisciplinary team in which experimentalists and clinicians work closely with mathematicians and computational biologists to identify key features of spatial datasets. You will work in collaboration with the research groups of Leedham and Byrne and the GO-PRECISE team. You will be responsible for the identification of novel spatial biomarkers in spatial transcriptomics data, providing insight into the biological mechanisms identified by data analysis methods in collaboration with quantitative researchers. Your work will establish new antigen markers of cancer that could be targeted with cancer vaccines. The generation of spatial data in biology has been transformed by multiplex imaging and spatial-omics technologies, such as single cell spatial transcriptomics. These approaches permit detailed mapping of phenotypic information about individual cells and their spatial locations within tissue sections. You will use MuSpAn, a Python toolbox for multiscale analysis of spatial data created by our group, to develop pipelines for high-throughput data analysis of spatial transcriptomics images (www.muspan.co.uk). This work will be supported in collaboration with Prof Byrne’s group at the Wolfson Centre for Mathematical Biology and other researchers in the Applied Spatial Biology Oxford group. 1 Responsibilities You will: • • • • • • • • • Manage your own academic research and administrative activities. Adapt existing and develop new research methodologies and materials. Analyse quantitative data from a variety of sources, particularly from Spatial Transcriptomics and Spatial Proteomics platforms. Collaborate with colleagues from the Mathematical Institute, Centre for Human Genetics, and the GO-PRECISE Alliance. Collaborate on the preparation of scientific reports and journal articles, present papers and posters at conferences/workshops. Contribute to community activities such as seminars and networking events. Develop skills in many areas of computational biological research via independent study and training courses. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Selection criteria Essential • • • • • • • Hold a PhD/DPhil (or close to completion) in experimental or theoretical biology, bioinformatics, clinical medicine, or a related discipline. Demonstrated ability to analyse and interpret complex multidimensional data. Experience of working with biomedical datasets, such as cancer data and/or spatial data. Excellent communication skills, including the ability to communicate effectively with researchers from outside your discipline, write for publication and present research proposals and results, and represent the research group at meetings. Experience of programming in Python, or demonstrated ability to rapidly acquire fluent knowledge of new programming languages, libraries, and platforms. The ability to work independently and to pursue research as part of an interdisciplinary team. A good publication record, for your career stage. Desirable • • • Background and/or interest in mathematics or computer science. Demonstrated enthusiasm for working across disciplinary boundaries with quantitative researchers (mathematicians, computer scientists, physicists, statisticians etc.). Good organisational skills. 2 Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • • • Lone Working Regular manual handling Travel outside of Europe or North America on University Business 3 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents. • http://www.ox.ac.uk/about_the_university/jobs/research/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that: • • As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy 4 Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 5
We are seeking to appoint a highly motivated Postdoctoral Researcher with expertise in innate immune responses to cancer, in vivo/in vitro experimental models, and advanced molecular techniques to join the group at Ludwig Institute for Cancer Research. This position offers an exciting opportunity to lead innovative projects at the intersection of epigenetics and tumour immunology. By leveraging advanced functional genomics, transcriptomics, and proteomics approaches, you will develop novel therapeutic strategies for cancer immunotherapy. You will be responsible for managing your own academic research and administrative activities. You will design and conduct experiments to investigate the role of epigenetic factors in innate immune response regulation. Your work will involve disease modelling, including murine in vivo models, as well as in vitro studies using primary in-vivo and patient samples. You will apply flow cytometry to monitor immune responses and utilize next-generation sequencing technologies for deep molecular insights. Additionally, you will present your findings at national and international conferences, mentor junior researchers in the lab, and contribute to high-impact publications in top-tier scientific journals. It is essential that you hold a PhD/DPhil (or close to completion) in tumour immunology or a related life science field together with background in cancer research. You will also have experience in vivo/in vitro experimental models, functional genomics (CRISPR, shRNA), molecular biology. You will possess a strong skills in decision-making, problem-solving, planning and organising analysis and research. Experience with PDX models and primary leukemic cells is highly desirable. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract until 36 months and is funded by Ludwig. Only applications received before 12 midday on Thursday 29 May 2025 will be considered. Please quote 179087 on all correspondence.
Research Grade 7: Research Grade 7: salary in range £38,674 - £43,171 p.a. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year
Experimental Medicine, Nuffield Deparment of Medicine
We have an exciting opportunity for a Postdoctoral Research Assistant in the Interpretation of Spatial Transcriptomics and Proteomics for Colorectal Cancer. You will join the GO-PRECISE team at the Nuffield Department of Medicine, University of Oxford. GlaxoSmithKline and Oxford University (GO) launched the PRECISE Alliance (Pre- Cancer Biology and Immunoprevention) in 2024, with the aim of conducting deep exploration of cancer precursors (precancers) to identify their molecular vulnerabilities and developing methods to intercept them. The alliance is led by Professor Sarah Blagden. You will be responsible for managing your own academic research and administrative activities and adapting existing and developing new research methodologies and materials. You will analyse quantitative data from a variety of sources, particularly from Spatial Transcriptomics and Spatial Proteomics platforms, and collaborate with colleagues from the Mathematical Institute, Centre for Human Genetics, and the GO-PRECISE Alliance. Other duties will include contributing to community activities such as seminars and networking events and developing skills in many areas of computational biological research via independent study and training courses. It is essential that you hold a PhD/DPhil (or close to completion) in experimental or theoretical biology, bioinformatics, clinical medicine, or a related discipline and have demonstrated ability to analyse and interpret complex multidimensional data. You will have experience of working with biomedical datasets, such as cancer data and/or spatial data, and experience of programming in Python, or demonstrated ability to rapidly acquire fluent knowledge of new programming languages, libraries, and platforms. A background and/or interest in mathematics or computer science would be highly desirable. Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV, and 2 referees as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a fixed term contract until 31 December 2027 and is funded by GlaxoSmithKline. Only applications received before 12 midday on 12 May 2025 will be considered. Please quote **178278** on all correspondence.
Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Old Road Campus, Oxford, OX3 7LF
sede principale
Are you passionate about taking a lead role in a cutting-edge project at the intersection of genomics, computational biology, and haematological cancer? We have an exciting opportunity for a Senior Postdoctoral Researcher to be a part of a collaborative interdisciplinary initiative at the Ludwig Institute for Cancer Research which aims to elucidate the molecular mechanisms and early biomarkers of progression to secondary acute myelogenous leukaemia (sAML). You will take a lead on developing data analysis approaches to search for targetable genetic, epigenetic, or epitranscriptomic mechanisms of progression to sAML. You will contribute to the study and sequencing design, collaborate with experimental biologists to validate the hypotheses, and advise and supervise computational staff and students. You will write research articles and present the results at national and international conferences. It is essential that you hold a PhD/DPhil in computational biology, genomics, bioinformatics, computer science, statistics, or a related field together with strong programming skills in Python, R, or similar languages, and proficiency in high-performance computing. You will have experience in large-scale genomic data analysis. You will be able to demonstrate how to organise and prioritise work efficiently, work independently and deliver high quality novel research in relevant fields. It is desirable that you have knowledge of epigenetic modifications and mechanisms and experience in single-cell data analysis. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract for 36 months and is funded by Ludwig. Only applications received before 12 midday on Thursday 15 May 2025 will be considered. Please quote **178673 **on all correspondence.
We are seeking to appoint an experienced Senior Operations and Programme Manager to oversee the delivery of a multi-project scientific programme at the Centre for Genomic Pathogen Surveillance, Pandemic Science Institute, Nuffield Department of Medicine. Focussed on the delivery of capacity, new technology, including genomics, and driven to make an impact in supporting countries and nations within the fight against infectious disease, CGPS host the NIHR Global Health Research Unit on Genomic Surveillance of AMR, working in tandem with partners in Nigeria, India, Colombia and The Philippines to exemplify approaches to surveillance which can be adopted elsewhere. This aligns with the development of strategy within the CGPS hosted World Health Organisation (WHO) Collaborating Centre on Genomic Surveillance of AMR. We are looking for a dynamic and experienced individual to manage and grow strategies, and support efforts to rollout our projects. You will be responsible for leading a large portfolio of multi-year scientific and global health projects, and you will support and drive CGPS interactions with international stakeholders, as well as representatives from national and international public health bodies, including the World Health Organisation. You will be responsible for organising and chairing meetings, committees, and working groups related to the program and playing a leading role in growing external networks and cross-sector initiatives to benefit CGPS and the University. To be successful in this role, you will hold a postgraduate degree with demonstrable experience in leading and managing complex scientific projects/programmes successfully, or be educated to an undergraduate level with an excellent and extensive track record of leading and managing successful scientific projects/programmes. You will have the ability to demonstrate leadership of a large and complex programme, for example, with multiple stakeholders, multi-disciplinary teams, multiple budgets, and regulatory complexity. You will be highly organised with the ability to manage a vast amount of relatively complex information and to prioritise a demanding workload with competing deadlines. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract for 2 years and is funded by the National Institute for Health Research (NIHR). For informal enquiries, please contact Prof. David Aanensen (David.aanensen@bdi.ox.ac.uk). Only applications received before 12 midday on 29 May 2025 will be considered. Please quote 178959 on all correspondence.
We have an exciting opportunity for a Postdoctoral Research Assistant in the Interpretation of Spatial Transcriptomics and Proteomics for Colorectal Cancer. You will join the GO-PRECISE team at the Nuffield Department of Medicine, University of Oxford. GlaxoSmithKline and Oxford University (GO) launched the PRECISE Alliance (Pre-Cancer Biology and Immunoprevention) in 2024, with the aim of conducting deep exploration of cancer precursors (precancers) to identify their molecular vulnerabilities and developing methods to intercept them. The alliance is led by Professor Sarah Blagden. You will be responsible for managing your own academic research and administrative activities and adapting existing and developing new research methodologies and materials. You will analyse quantitative data from a variety of sources, particularly from Spatial Transcriptomics and Spatial Proteomics platforms, and collaborate with colleagues from the Mathematical Institute, Centre for Human Genetics, and the GO-PRECISE Alliance. Other duties will include contributing to community activities such as seminars and networking events and developing skills in many areas of computational biological research via independent study and training courses. It is essential that you hold a PhD/DPhil (or close to completion) in experimental or theoretical biology, bioinformatics, clinical medicine, or a related discipline and have demonstrated ability to analyse and interpret complex multidimensional data. You will have experience of working with biomedical datasets, such as cancer data and/or spatial data, and experience of programming in Python, or demonstrated ability to rapidly acquire fluent knowledge of new programming languages, libraries, and platforms. A background and/or interest in mathematics or computer science would be highly desirable. Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV, and 2 referees as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a fixed term contract until 31 December 2027 and is funded by GlaxoSmithKline. Only applications received before 12 midday on 12 May 2025 will be considered. Please quote 178278 on all correspondence.
The NDM Grant Management Team are an ambitious and supportive group, delivering high quality, professional grant management support across a broad portfolio of research projects. As a Senior Grants Officer, working under the supervision of the Research Grant Manager, this position offers an excellent opportunity for career progression in Research Administration, working alongside researchers at the leading edge of science in the largest medical department at Oxford. You will assume full responsibility for a range of activities which support the financial and operational management of a significant and complex portfolio of research projects. You will play a central role in liaising with academic staff, central university services such as Research Services and Research Accounts, and external collaborators and funders. You will be expected to work closely with grant holders and Professional Services staff to maintain and develop an efficient research administration service. It is essential that you are educated to degree level or equivalent related experience, with knowledge of grants and/or contracts. You will have experience of financial administration, as well as experience of interpreting and applying financial policies. Your excellent interpersonal skills will give you the ability to use tact and discretion to build effective and cooperative working relationships with colleagues at all levels. The ability to work independently is key and you will have a systematic, thorough, and well- organised approach to work. A high level of self-motivation and the ability to thrive in a busy environment is a must, ensuring that research grants are managed effectively so that targets and deadlines are met. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a permanent contract. Please note that all shortlisted candidates will be invited for interview on the week commencing Monday 19th May 2025. Only applications received before 12 midday on Wednesday 14 May 2025 will be considered. Please quote **179104 **on all correspondence.
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178283 - Postdoctoral Research Assistant - JD
Job title Postdoctoral Researcher in Neuronal Dysfunction in Alzheimer’s Disease, Oxford-GSK Institute of Molecular and Computational Medicine Division Medical Sciences Department Nuffield Department of Medicine Location Department of Physiology, Anatomy and Genetics, Dorothy Crowfoot Hodgkin Building, Sherrington Road, Oxford, OX1 3QU On occasion, the Centre for Human Genetics, Building for Genomic Medicine, Roosevelt Drive, Headington, Oxford, OX3 7BN Grade and salary Research Grade 7: Salary in range £38,674 - £46,913 per annum. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year Hours Full time Contract type Fixed-term contract until 30 September 2027 Funding is provided by GSK Reporting to Dr Hugo Fernandes, Alzheimer’s Society Dementia Research Leader Fellow, with oversight from Dr Georgina Kerr, Senior Programme Manager Vacancy reference 179348 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship under UK Visas and Immigration legislation. About us What we offer • • • University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - https://www.chg.ox.ac.uk/ / www.imcm.ox.ac.uk / https://www.dpag.ox.ac.uk/ https://hr.admin.ox.ac.uk/staff-benefits • An excellent contributory pension scheme • 38 days annual leave • A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata) • A comprehensive range of childcare services • Family leave schemes • Cycle loan scheme • Discounted bus travel and Season Ticket travel loans • Membership to a variety of social and sports clubs • A welcoming and diverse community The role This post provides an exciting opportunity to join the newly established multidisciplinary Oxford-GSK Institute of Molecular & Computational Medicine (IMCM) operating within Nuffield Department of Medicine (NDM) in collaboration with Nuffield Department of Clinical Neuroscience (NDCN), Sir William Dunn School of Pathology, Department of Psychiatry, and Department of Physiology, Anatomy and Genetics (DPAG). The Institute brings together the very best scientific, clinical, technological and computational expertise from Oxford University and GSK forming a unique industry/academic partnership. The aim of the Institute is to improve tools in, and knowledge from, genetics, genomics, molecular and single cell biology, spatial imaging, machine learning and novel methods of data handling to study the pattern of diseases in new ways. The Institute will develop disease agnostic platforms to change the clinical practise of pathology, helping to identify and validate early potential drug targets, and biomarkers to predict disease progression. The Institute is built around Fellows and Oxford-GSK project teams located across different departments within the Medical Sciences Division. Projects will initially focus on neurodegeneration and the central nervous system, specifically Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis but it is anticipated the range of activities will expand into other research areas in future. You will be a member of the group of Dr. Hugo Fernandes, an Alzheimer’s Society Dementia Research Leader Fellow and a Group Leader at the Department of Physiology, Anatomy and Genetics and the Kavli Institute for Nanoscience Discovery. The Fernandes group has vast experience in neurodegenerative disease in vitro modelling using human Induced Pluripotent Stem Cells (iPSC) and has advanced our understanding of molecular mechanism of neuronal dysfunction in Parkinson’s and Alzheimer’s disease. The group has developed and optimized methods for differentiation of diverse iPSC-neuronal subtypes and has contributed to the understanding of metabolic regulation of neuronal function in health using genetic CRISPR screens, organellar functional assays and single-cell multiomics profiling. In this postdoctoral role, you will work with iPSC-neurons to characterize neuronal dysfunction and establish co-culture models with iPSC-microglia to define mechanisms underlying neuroinflammation. These cell models will be challenged with material isolated from post-mortem brains donated by a large cohort of Alzheimer’s patients to the Oxford Brain Bank in collaboration with Professor Laura Parkkinen (Nuffield Department of Clinical Neuroscience). Neuronal dysfunction will be assessed through a range of cell-based assays and multi-omics approaches, in collaboration with Dr Sally Cowley (Sir William Dunn School of Pathology), working closely with a PDRA in her team. Responsibilities You will: • • • Culture and manipulate human induced Pluripotent Stem Cell lines and undertake their differentiation into neurons and microglia. Design, validate, troubleshoot, and perform relevant assays to interrogate dysregulation induced in iPS-neurons by exposure to material from Alzheimer’s brains. This will require standard cell and molecular biology methodologies, including qPCR, Western Blot, FACs, pharmacological and CRISPR-mediated genetic manipulation of intracellular signalling/trafficking pathways, organelle specific functional assays, high content imaging (Opera Phenix) and automated image analysis. It will also involve processing of samples for multi-omics analyses inlcuding transcriptomics, proteomics and lipidomics. Develop an iPS-neuronal-microglial co-culture screening platform that can assess synaptic function and synaptic loss. 1 • • • • • • • • • • • Keep meticulous, detailed records of your work and commit to engaging with cloud-based analyses on the IMCM data platform. Organise and prioritise your work efficiently and work to the highest standard to meet agreed deadlines. Communicate effectively with colleagues at all levels both within Oxford and at GSK to identify needs, risks and develop appropriate solutions, escalating where appropriate. Be flexible and responsive to the changing needs of individual projects. Collaborate with peer scientists from cross-functional teams to analyse and interpret large complex datasets and communicate findings. Prepare manuscripts for publication and contribute to written and oral presentations/reports as required. Promote the Oxford-GSK IMCM locally and nationally and disseminate research outcomes to advance knowledge in the specialist area. Represent the Oxford-GSK IMCM at external meetings/seminars. Perform other relevant duties as required to support the group’s activities. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Job descriptions can never be comprehensive and you may be required to undertake other similar tasks and responsibilities. Selection criteria Essential • • • • • • • • • Hold a PhD/DPhil (or close to completion) in biochemistry, molecular biology, neuroscience or a related field. Experience in cell culture, preferably human pluripotent stem cells. Knowledge of neurodegenerative diseases, such as Alzheimer’s Disease. Knowledge of differentiation of iPSCs into neuronal and glial cultures. Experience in molecular biology methodologies, following and adapting protocols and setting up cellular assays including image-based. Excellent communication skills, including the ability to write for publication, present results, and represent the research group at meetings. Be highly motivated, organised, keep meticulous records and have the capacity to think creatively. Ability to manage own research and administrative activities. Commitment to engage with, and promote awareness of, equality, diversity and inclusion and embedding these into your work. Desirable • • • • • Experience of working with iPSC-neuronal cultures. Experience of working productively in a multi-disciplinary team. Experience of integrative analyses with other data modalities. Knowledge of neuroinflammation. Experience with preparation of samples for multi-omics analysis (single-cell and bulk) and analysis of large omics-datasets. 2 Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • • • Regular manual handling Working with blood, human products and human tissues Work with any substance which has any of the following pictograms on their MSDS: 3 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents. • http://www.ox.ac.uk/about_the_university/jobs/research/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that: • • As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy 4 Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 5
We are seeking four Senior Postdoctoral Researchers to join a new Oxford-GSK partnership focused on biostatistics and artificial intelligence (AI) for application in medicine. Each Senior Postdoctoral Researcher will play a key role in shaping the research within the thematic areas of interest. With a cross-departmental base, the partnership will bring together the University of Oxford’s expertise in statistics, mathematics, engineering and AI with industry scientists. Within the partnership, small research teams will focus on ambitious, ‘blue sky’ research for novel methods development relevant for drug discovery analysis pipelines, trial design and operational efficiency. Led by Professor Chris Holmes, and with scientific oversight from Oxford Principal Investigators and GSK scientists, the centre will initially focus on some of the following thematic areas: • Decision analysis under model misspecification • Uncertainty quantification around LLMs • Constrained optimal experimental design (active learning) • Combining models and combining data / Realistic simulation of clinical trials • Developing LLMs to utilise ODEs and ProbML as tools; Code synthesis for causality • Generalisability, transportability and validation of multiomics ML across biobanks More details on thematic areas can be found here; https://www.bdi.ox.ac.uk/research/oxford-gsk-collaboration-in-biostatistics- and-artificial-intelligence-in-medicine As a Senior Postdoctoral Researcher, you will be responsible for planning and managing your own research programme within the collaboration. You will work closely with Principal Investigators and industry scientists to agree clear task objectives, organise work and delegate as appropriate, keeping accurate and comprehensive records of work undertaken. You will contribute intellectually to the development of ‘pathfinder’ projects and help shape the direction of research themes and the wider partnership in the longer term for delivery of new methods relevant for drug discovery analysis pipelines, trial design and operational efficiency. Other responsibilities will include helping with supervision of PhD students working on projects as part of the initiative, performing analysis in close contact with the associated clinical researchers and taking responsibility for completion of data analyses. You will communicate on a regular basis with the relevant theme leads (Oxford and GSK) and wider team on all issues relating to the development and application of new methods, ensuring they are kept fully up to date with progress and difficulties in the research projects. It is essential that you hold a PhD/DPhil in a quantitative or computer science related subject (e.g. Statistics, Machine Learning, Biostatistics, AI, Engineering), and have post-qualification research experience. You will have experience in and an ability to develop research projects, with a strong publication record in peer-reviewed journals and conferences. You will have a proven ability in providing intellectual support and technical advice on projects and in assisting others in tools relating to data processing and analysis. A forward-thinking, collaborative approach to research will be essential to meet the aims of the partnership. Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must **specify which thematic areas you are interested in working on** , and **explain how you meet each of the selection criteria** for the post using examples of your skills and experience. This position is offered full time on a fixed term contract until 30 September 2028 and is funded by GSK. Only applications received before 12 midday on 19 May 2025 will be considered. Please quote **177230** on all correspondence.
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178278 - Postdoctoral Research Assistant - JD
Research Grade 6: Research Grade 6: £34,982 - £40,855 with a discretionary range to £45,628 p.a. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year.
About the Role The Peter Medawar Unit Administrator is an exciting opportunity for someone who is keen to work in a supporting role for a world leading research building, and who would be motivated by the opportunity to help find solutions so the building runs efficiently and effectively. A positive and flexible attitude is important, with a pro-active approach to the role. In addition, experience of administrative work in a university context and within the OUHT would be highly desirable. The administration team that supports the building is based on Level 5 of the John Radcliffe. This post will have close working relations with the team in order to ensure the administrative processes of the Building run smoothly. On a daily basis the Unit Administrator will liaise with the Chairman of the Building, the Laboratory Manager and the other members of the PMB management committee. About You To be considered for this position you should have; • Considerable experience of administrative and project management support for project delivery; • Excellent interpersonal skills, professional demeanour and a proactive and flexible approach to work; • High level of motivation with the ability to prioritise and drive your own work against deadlines while being respectful of other individuals responsibilities; • Evidence of knowledge in improvement schemes in Health Science, preferably with experience of compliance with government directives; • Website management skills; • Negotiation skills; • Ability to multitask including the ability to handle several complex assignments at once; About the Nuffield Department of Clinical Medicine The Nuffield Department of Clinical Medicine (NDM) is one of the largest departments of the University of Oxford and is part of the Medical Sciences Division, with responsibility for a significant part of the teaching of clinical students within the Medical School. Benefits of working University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits Application Process This position is available for up to three years in the first instance. Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Only applications received before 12:00 midday on Friday 23/05/2025 will be considered.
Offices of the Nuffield Professor of Medicine, Henry Wellcome Building, Headington, Oxford OX3 7BN
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Current vacancies at the University of Oxford
Job title Research Grants Manager Division Medical Sciences Department Nuffield Department of Medicine Location NDM Operations, Grant Management Team, based at the Li Ka Shing Centre for Health Information and Discovery, Old Road Campus, Heading, Oxford, OX3 7LF Grade and salary Standard Grade 7: £38,674 - £46,913 with a discretionary range to £51,059 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata). Hours Full time Contract type Permanent Reporting to Deputy Head of Grant Management Vacancy reference 179385 Hybrid working arrangements The successful person will need to work on site for a minimum of 3 days per week Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship. About us   What we offer https://hr.admin.ox.ac.uk/staff-benefits  An excellent contributory pension scheme  38 days annual leave  A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata)  A comprehensive range of childcare services  Family leave schemes  Cycle loan scheme  Discounted bus travel and Season Ticket travel loans  Membership to a variety of social and sports clubs  A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk The role The role of the Research Grants Manager is a key position within the NDM Grant Management Team, reporting to the Deputy Head of Grant Management (DHoGM). Our key objective is to provide an outstanding professional service to manage the cradle-to-grave process of research grants. This position offers an excellent opportunity to work alongside researchers at the leading edge of science in the largest medical department at Oxford. You will manage an assigned portfolio of research projects, ensuring that the needs of the academics and professional services, and the requirements of research funders, are met. You will have line management responsibility for a number of grant staff supporting the portfolio assigned to you, and you will be expected to support other Research Grant Managers as required. You will support the HoGM in growing and developing the Team, ensuring delivery of consistent, high quality, professional project support across the Department. Responsibilities You will: Management of the Research Awards Process (pre and post award)        Have overarching management responsibility for the administration of a portfolio of research grants, ensuring that applications and awards have the appropriate institutional approvals, and comply with funder terms and conditions and University policies, promoting a ‘right first-time’ culture. Oversee the provision of financial management for all awards in the allocated portfolio, ensuring that funder requirements, including audit requirements, are met. This will require you to work closely with the senior Professional Sevices staff, Project Managers, grant holders, and where applicable, the NDM Finance Shared Service Centre. Actively manage the administration that underpins collaborations with other institutions both in the UK and overseas, ensuring that if the Department is the lead collaborator, mechanisms are in place to provide appropriate assurance for the University on activities and expenditure. Provide additional support as required to grant holders and senior Professional Sevices staff with large, complex research grants that are strategically important for the Department, including the timely coordination of planning meetings with key stakeholders where necessary. Assign tasks and delegate responsibilities to the Senior Grants Officers and Grants Officers within your allocated portfolio. Proactively meet with any grant holders and senior Professional Sevices staff within the allocated portfolio, to address complex issues as they arise with a view to providing solutions to problems, while ensuring that the project remains compliant with funder terms and conditions (including robustness under audit scrutiny). Work closely with grant holders to ensure that expenditure is appropriately allocated to research projects and monitored in line with budgets, and in accordance with University policies and the funder terms and conditions. Internal and external communication  Represent the Department at meetings as requested by the HoGM or DHoGM (for example the Research and Innovation Support Network or RISN) to understand the broader research funding landscape. 1    Attend regular and ad hoc grant management meetings as required, providing advice and query resolution for the grant holder, Professional Sevices staff, or Research Services or Research Accounts. Escalate issues that require the involvement of the HoGM in a timely manner. Liaise with external funders, as required, and maintain an up-to-date knowledge of major funding bodies’ terms and conditions. Training and Development    Line manage Senior Grants Officers and Grants Officers to maintain an effective team structure, setting and monitoring objectives and overseeing the efficient allocation of resources. Foster a positive team culture, promoting core values and behaviours. Support the ongoing training of Senior Grants Officers, Grants Officers, and Apprentices within the Team. Deliver training of grant management to relevant staff, as requested. Information Management     Implement processes and procedures within your team to ensure compliance with University, Divisional, and Departmental policies. Support the HoGM in the development of information management systems that meet the needs of the grant management team, grant holders, and University/funder reporting requirements. Ensure that up-to-date Standard Operating Procedures for research administrative processes are followed and that these are communicated to colleagues. Maintain the department’s information on any relevant in-house systems as required. Other responsibilities      Provide cover for other Research Grant Managers as required. Support the Department’s Athena SWAN and EDI programmes as required. Work with other colleagues to foster a positive team culture, and model and promote core values and behaviours. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Job descriptions can never be comprehensive and you may be required to undertake other similar tasks and responsibilities. 2 Selection criteria Essential            Educated to degree level or equivalent. Related experience, ideally in the higher education sector or research environment. Working knowledge of the major funding bodies, and of current issues affecting the research funding sector. A systematic, thorough, and well-organised approach to work with a proven ability to prioritise a heavy and varied workload and to keep track of a large volume of on-going projects. Demonstrable skills in effective people management and the ability to support, develop, and motivate staff. Able to work independently with minimal/no supervision, but also a team player who works well within a team. A flexible and adaptable approach to work, with a demonstrable ability to diagnose problems and develop solutions, both independently and as part of a team-based approach. Excellent inter-personal skills, including the ability to use tact and discretion to build effective and cooperative working relationships with colleagues across a diverse range of seniority and expertise. Excellent numeracy skills and confidence in dealing with financial data with the ability to analyse and understand that data and present it effectively to others Excellent IT skills for creating and managing information, including experience in the use of the Microsoft Office Suite, particularly Word, PowerPoint and Excel, and the ability to learn new systems. High levels of accuracy and attention to detail when inputting data and providing information. Desirable    Experience of Oracle Financials software or other financial software. Experience of the University’s costing and pricing tool, X5. Experience of working with industry partners and collaborators 3 Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows:   Regular manual handling Travel outside of Europe or North America on University Business 4 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents.  http://www.ox.ac.uk/about_the_university/jobs/professionalandmanagement/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that:   As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates 5 Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 6
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We are seeking an enthusiastic and highly motivated Research Assistant to join the Owen lab to work within the Ludwig Institute for Cancer Research at the University of Oxford. This pioneering project focuses on characterising patient-derived oesophageal and gastric cancer tissues as part of prospectively approved clinical trials and developing personalised models understand therapy response characteristics. This is a unique opportunity to work in a tissue-focused translational research group aiming to enhance oesophageal cancer cure in a collaborative and highly clinically relevant way. Your role will also involve handling and processing human tissue samples, establishing and maintaining 3D patient-derived AVATAR models, and performing a range of molecular biology and immunological assays such as immunohistochemistry, PCR, and flow cytometry. You will assist with data collection, interpretation, and the presentation of findings at lab meetings and to external collaborators, while liaising closely with clinicians, researchers, and industry partners. Additionally, you will ensure compliance with health and safety protocols, maintain accurate research documentation, and support the general upkeep of the laboratory. It is essential that you hold a degree in biomedical sciences, molecular biology, cancer biology, or a related discipline, and have hands-on experience with molecular and cellular biology techniques such as immunohistochemistry and flow cytometry. You should possess strong organisational and record- keeping skills, be comfortable working both independently and as part of a multidisciplinary team, and have excellent communication skills to liaise effectively with clinicians, researchers, and collaborators. A willingness to handle and process human tissue samples in line with ethical and regulatory guidelines is also required. In addition, it would be desirable for you to hold a Master’s degree or have equivalent experience in a relevant research field, along with prior experience working with cell culture, knowledge of cancer immunology, and familiarity with image analysis software. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract until 31 March 2026 and is funded by the BRC. Only applications received before 12 midday on 4 June 2025 will be considered. Please quote **179039** on all correspondence.
The Oxford-GSK Institute of Molecular & Computational Medicine has a new and exciting opportunity for a Postdoctoral Researcher, specialising in Neuronal Dysfunction in Alzheimer’s Disease, to join the Institute. The Institute is built around Fellows and Oxford-GSK project teams located across different departments within the Medical Sciences Division. Projects will initially focus on neurodegeneration and the central nervous system, specifically Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis but it is anticipated the range of activities will expand into other research areas in future. Based within the group of Dr Hugo Fernandes at the Department of Physiology, Anatomy and Genetics, you will be responsible for designing, validating, troubleshooting, and performing relevant assays to interrogate dysregulation induced in iPS-neurons by exposure to material from Alzheimer’s brains. You will develop an iPS-neuronal-microglial co-culture screening platform that can assess synaptic function and synaptic loss, and keep meticulous, detailed records of your work and commit to engaging with cloud-based analyses on the IMCM data platform. Other duties will include collaborating with peer scientists from cross-functional teams to analyse and interpret large complex datasets and communicate findings, and promoting the Oxford-GSK IMCM locally and nationally and disseminating research outcomes to advance knowledge in the specialist area. It is essential that you hold a PhD/DPhil (or close to completion) in biochemistry, molecular biology, neuroscience or a related field, and have experience in cell culture, preferably human pluripotent stem cells. You will have knowledge of neurodegenerative diseases, such as Alzheimer’s Disease, and of differentiation of iPSCs into neuronal and glial cultures. Experience in molecular biology methodologies, following and adapting protocols and setting up cellular assays including image-based is essential for this role, and knowledge of neuroinflammation would be highly desirable. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract until 30 September 2027 and is funded by GSK. Interviews will be held on 4 June 2025. Only applications received before 12 midday on 22 May 2025 will be considered. Please quote **179348** on all correspondence.
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We are seeking four Senior Postdoctoral Researchers to join a new Oxford-GSK partnership focused on biostatistics and artificial intelligence (AI) for application in medicine. Each Senior Postdoctoral Researcher will play a key role in shaping the research within the thematic areas of interest. With a cross-departmental base, the partnership will bring together the University of Oxford’s expertise in statistics, mathematics, engineering and AI with industry scientists. Within the partnership, small research teams will focus on ambitious, ‘blue sky’ research for novel methods development relevant for drug discovery analysis pipelines, trial design and operational efficiency. Led by Professor Chris Holmes, and with scientific oversight from Oxford Principal Investigators and GSK scientists, the centre will initially focus on some of the following thematic areas: • Decision analysis under model misspecification • Uncertainty quantification around LLMs • Constrained optimal experimental design (active learning) • Combining models and combining data / Realistic simulation of clinical trials • Developing LLMs to utilise ODEs and ProbML as tools; Code synthesis for causality • Generalisability, transportability and validation of multiomics ML across biobanks More details on thematic areas can be found here; https://www.bdi.ox.ac.uk/research/oxford-gsk-collaboration-in-biostatistics-and-artificial-intelligence-in-medicine As a Senior Postdoctoral Researcher, you will be responsible for planning and managing your own research programme within the collaboration. You will work closely with Principal Investigators and industry scientists to agree clear task objectives, organise work and delegate as appropriate, keeping accurate and comprehensive records of work undertaken. You will contribute intellectually to the development of ‘pathfinder’ projects and help shape the direction of research themes and the wider partnership in the longer term for delivery of new methods relevant for drug discovery analysis pipelines, trial design and operational efficiency. Other responsibilities will include helping with supervision of PhD students working on projects as part of the initiative, performing analysis in close contact with the associated clinical researchers and taking responsibility for completion of data analyses. You will communicate on a regular basis with the relevant theme leads (Oxford and GSK) and wider team on all issues relating to the development and application of new methods, ensuring they are kept fully up to date with progress and difficulties in the research projects. It is essential that you hold a PhD/DPhil in a quantitative or computer science related subject (e.g. Statistics, Machine Learning, Biostatistics, AI, Engineering), and have post-qualification research experience. You will have experience in and an ability to develop research projects, with a strong publication record in peer-reviewed journals and conferences. You will have a proven ability in providing intellectual support and technical advice on projects and in assisting others in tools relating to data processing and analysis. A forward-thinking, collaborative approach to research will be essential to meet the aims of the partnership. Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must specify which thematic areas you are interested in working on, and explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a fixed term contract until 30 September 2028 and is funded by GSK. Only applications received before 12 midday on 19 May 2025 will be considered. Please quote 177230 on all correspondence.
Research Grade 8: Research Grade 8: £48,235 - £57,255 with a discretionary range to £64,228 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata).
**THIS IS A RE ADVERTISMENT PREVIOUS APPLICANTS NEED NOT APPLY ** We are looking for a Trial Manager to join the Oxford Respiratory Trials Unit for maternity leave cover. This post is also being offered as a 1 year secondment opportunity. The Trial Manager will be responsible for planning and overseeing the set up and management of a variety of studies conducted at ORTU and providing support to the Senior Trial Manager. This post requires someone who can work both as a member of a multi-disciplinary team and independently, using their initiative to seek solutions to problems and provide excellent administrative support. You will be responsible for the day-to-day management of ORTU studies - supporting Chief Investigators, Trial Assistants and Assistant Trial Managers in applying for regulatory approvals for trials including MHRA, ethics, HRA and Research & Development (R&D) approvals. You will also be responsible for organising team meetings, answering and resolving queries on trial conduct. In this post you will maintain oversight of the overall conduct and performance of studies within the portfolio. This will include predicting, identifying and resolving problems that are critical to the conduct of studies managed by the ORTU and planning to strategically avoid them. You will also have the opportunity contribute to the CTU quality management system, reviewing and writing SOPs and developing procedural documentation, as applicable. There will be opportunity for some hybrid office/remote working in line with department guidance e.g one to two days at home depending on working hours/pattern. The Unit has a core office day on a Thursday. **About You** Applicants should be educated to degree level in a relevant subject or have considerable experience in the set-up and ongoing monitoring and management of large complex multi-site clinical trials. You will also need to demonstrate that you have: • Good communication skills (oral and written), confident and articulate, and able to work across professional team and organisational boundaries to deliver training and work well with staff at all levels. • A range of IT skills (Word, Excel, PowerPoint, Outlook,) as demonstrated in part by your application. • Experience of writing Standard Operating Procedures, Trial Specific Procedures and working within a Quality Management System. • Experience of planning and progressing work activities using own initiative without supervision, prioritising own schedule and that of others, dividing time between projects appropriately. • Thorough knowledge of the regulatory and governance requirements for UK clinical trials – including submission of applications to these bodies. Having had previous experience in a respiratory trial setting and experience of CTIMP and Device Trials are both desirable capabilities for this post. **About the Nuffield Department of Clinical Medicine** The Nuffield Department of Clinical Medicine (NDM) is one of the largest departments of the University of Oxford and is part of the Medical Sciences Division, with responsibility for a significant part of the teaching of clinical students within the Medical School. **Benefits of working** University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits **Application Process** Please contact Emma Hedley emma.hedley@ndm.ox.ac.uk or Ellie Daly ellie.daly@ndm.ox.ac.uk for more details. The post is full time and fixed term to cover maternity leave for 12 months and is available from June 2025. This role can also be a secondment opportunity. Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Only applications received before 12:00 midday on Thursday 15th May 2025 will be considered.
We are seeking to appoint an experienced Senior Operations and Programme Manager to oversee the delivery of a multi-project scientific programme at the Centre for Genomic Pathogen Surveillance, Pandemic Science Institute, Nuffield Department of Medicine. Focussed on the delivery of capacity, new technology, including genomics, and driven to make an impact in supporting countries and nations within the fight against infectious disease, CGPS host the NIHR Global Health Research Unit on Genomic Surveillance of AMR, working in tandem with partners in Nigeria, India, Colombia and The Philippines to exemplify approaches to surveillance which can be adopted elsewhere. This aligns with the development of strategy within the CGPS hosted World Health Organisation (WHO) Collaborating Centre on Genomic Surveillance of AMR. We are looking for a dynamic and experienced individual to manage and grow strategies, and support efforts to rollout our projects. You will be responsible for leading a large portfolio of multi-year scientific and global health projects, and you will support and drive CGPS interactions with international stakeholders, as well as representatives from national and international public health bodies, including the World Health Organisation. You will be responsible for organising and chairing meetings, committees, and working groups related to the program and playing a leading role in growing external networks and cross-sector initiatives to benefit CGPS and the University. To be successful in this role, you will hold a postgraduate degree with demonstrable experience in leading and managing complex scientific projects/programmes successfully, or be educated to an undergraduate level with an excellent and extensive track record of leading and managing successful scientific projects/programmes. You will have the ability to demonstrate leadership of a large and complex programme, for example, with multiple stakeholders, multi-disciplinary teams, multiple budgets, and regulatory complexity. You will be highly organised with the ability to manage a vast amount of relatively complex information and to prioritise a demanding workload with competing deadlines. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract for 2 years and is funded by the National Institute for Health Research (NIHR). For informal enquiries, please contact Prof. David Aanensen (David.aanensen@bdi.ox.ac.uk). Only applications received before 12 midday on 29 May 2025 will be considered. Please quote **178959** on all correspondence.
Grade 9: £55,636 - £64,228 with a discretionary range to £70,029 per annum.
Postdoctoral Research Assistant in the Interpretation of Spatial Transcriptomics and Proteomics for Colorectal Cancer
Ludwig Institute for Cancer Research, Oxford Branch
We have an exciting opportunity for a Research Software Engineer to join the Centre for Human Genetics at the Nuffield Department of Medicine. You will be working closely with Professor Simon Leedham and Professor Helen Byrne at the Mathematical Institute University of Oxford. You will work as part of the Oxford Spatial Biology Group, a large multidisciplinary team of mathematicians, computational biologists, experimentalists and clinicians, and in collaboration with the research groups of Professors Leedham and Byrne and the Cancer Research UK Oxford Centre. You will support the development of our spatial biology software, MuSpAn. You will be responsible for designing and implementing high quality, reliable and maintainable software that will enable the translational impact of existing research. You will be collaborating with colleagues from the Mathematical Institute, Centre for Human Genetics, and Cancer Research UK Oxford Centre, to support the development and improvement of research software. You will train researchers within the University of Oxford on the effective use of software for research, contribute to the development of training material for workshops and courses offered by the Spatial Biology Group. It is essential that you hold a PhD/DPhil (or are close to completion) with a significant software development component, and have experience of software development in a research environment. You will also have experience of applying software engineering best practices (e.g. issue tracking, code review, testing, documentation and continuous integration). Demonstrated ability to rapidly acquire fluent knowledge of new programming languages, libraries, and platforms is essential, along with experience integrating Python code with lower-level functionality (e.g., speeding up python packages using C or C++ backends). You will have excellent communication skills, including the ability to communicate effectively with biomedical researchers, write for publication and present at meetings. Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a fixed term contract until 1 April 2027 and is funded by CRUK. Only applications received before 12 midday on Thursday 29 May 2025 will be considered. Please quote 177742 on all correspondence.
Job title Senior Postdoctoral Researcher in application of AI for medicine Division Medical Sciences Department Nuffield Department of Medicine Location Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Old Road Campus, Oxford, OX3 7LF Grade and salary Research Grade 8: Salary in range £48,235 - £51,059 per annum (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata). Hours Full time Contract type Fixed-term contract for 36 months Funding is provided by GSK Reporting to Professor Chris Holmes, Principle Investigator, and Partnership Theme Lead Vacancy reference 177230 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship under UK Visas and Immigration legislation. About us • • • What we offer https://hr.admin.ox.ac.uk/staff-benefits • An excellent contributory pension scheme • 38 days annual leave • A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata) • A comprehensive range of childcare services • Family leave schemes • Cycle loan scheme • Discounted bus travel and Season Ticket travel loans • Membership to a variety of social and sports clubs • A welcoming and diverse community Research topic AI and biostatistics with application to medicine Principal Investigator / supervisor Professor Chris Homes & Partnership Theme Lead Project team Oxford-GSK Centre for Biostatistics & AI in Medicine Funding partner The funds supporting this research project are provided by GSK University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - https://www.bdi.ox.ac.uk/ The role We are seeking four Senior Postdoctoral Researchers to join a new Oxford-GSK partnership focused on biostatistics and artificial intellegence (AI ) for application in medicine, each of whom will play a key role in shaping the research within thematic areas of interest. You will bring experience in a quantitative or computer science-related subject, with experience at the post-doctoral level, and a drive to work across a range of themes with research experts in a number of specialisms. Training will be provided for successful applicants across a variety of scientific disciplines, as required. Whilst you will be a member of the Nuffield Department of Medicine with a base in the Big Data Institute, the partnership offers an opportunity to work with leading Principal Investigators from Departments in other parts of the University, including Engineering Sciences, Computer Sciences, Statistics and Saïd Business School. This role is relevant both for candidates with a strong background in machine learning and seeking to branch out into healthcare, or with strengths in biostatistics and keen to develop in the area of machine learning. The Project The University of Oxford and GSK have recently formed a new partnership focused on biostatistics and artificial intelligence (AI) for application in medicine. The partnership will bring together the University of Oxford’s expertise in statistics, mathematics, engineering and AI with industry scientists, forming small teams focused on ambitious, ‘blue sky’ research for novel methods development relevant for drug discovery analysis pipelines, trial design and operational efficiency. Led by Professor Chris Holmes, with scientific oversight from Oxford Principal Investigators and GSK scientists, the centre will initially focus on the following thematic areas: • • • • • • Decision analysis under model misspecification Uncertainty quantification around LLMs Constrained experimental design Combining models and combining data / Realistic simulation of clinical trials Developing LLMs to utilise ODEs and ProbML as tools, Code synthesis for causality Generalisability, transportabilty and validation of multiomics ML across biobanks Please see https://www.bdi.ox.ac.uk/research/oxford-gsk-collaboration-in-biostatistics-and-artificialintelligence-in-medicine for further information on the thematic areas. Principal Investigators from Oxford for this programme are Professor David Clifton (Department of Engineering Science), Professor Robin Evans (Department of Statistics), Associate Professor Yarin Gal (Department of Computer Science), Associate Professor Agni Orfanoudaki (Saïd Business School) in and Associate Professor Tom Rainforth (Department of Statistics). Teams will have a base in the University of Oxford’s Big Data Institute and will be well supported by a dedicated data scientist, as well as a programme manager. 1 Responsibilities You will: • • • • • • • • • • • • Plan and manage own research programme within the collaboration. Work closely with senior academic researchers and industry scientists, to agree clear task objectives, organise work and delegate as appropriate, keeping accurate and comprehensive records of work undertaken. Contribute intellectually to the development of ‘pathfinder’ projects and help shape the direction of research themes and wider partnership in the longer term for delivery of new methods relevant for drug discovery analysis pipelines, trial design and operational efficiency. Willingness to work flexibly across thematic areas and projects where there is opportunity for added value and conceptual advancement, coaching other members of the group on specialist methodologies or analytical approaches. Write research articles at a national level for peer-reviewed journals, book chapters, and reviews. Present papers at national conferences, and lead seminars to disseminate research. Perform the analysis in close contact with the associated clinical researchers and to take responsibility for completion of data analyses. Communicate on a regular basis with the relevant theme leads (Oxford and GSK) and wider team on all issues relating to the development and application of new methods, ensuring they are kept fully up to date with progress and difficulties in the research projects. Present research project updates to the partnership senior leadership team as required. Work in collaboration with machine learning and statistics groups in the University to exploit existing resources, tools and methods to their full potential, maintaining confidentiality regarding research data when interacting with colleagues outside of the collaboration Assist with the supervision of doctoral students joining the partnership, assist with related teaching and other work for the departments that takes into account career development aims Perform any other comparable duties as may reasonably be required to ensure the efficient running of the collaboration. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. 2 Selection criteria Essential • • • • • • • Hold a PhD/DPhil in a quantitative or computer science related subject (eg Statistics, Machine Learning, Biostatistics, AI, Engineering). Post-qualification research experience. Extensive relevant research experience in a quantitative or computer science related subject and an ability to develop research projects, with a strong publication record in peer-reviewed journals and conferences. Excellent interpersonal, communication and team working skills, with an ability to collaborate effectively with computational, wet-lab and clinical scientists, while taking personal responsibility for assigned tasks. The proven ability to communicate technical advice and provide intellectual support, and assist others in tools relating to data processing and analysis. An approach to research which will directly contribute to, and benefit from, the forward thinking and collaborative ethos of the programme. A willingness and flexibility to work across a broad range of themes with scientists with distinct academic specialisms, and to branch out and develop skills across unfamiliar research areas (as necessary). Desirable • • • • • Experience of conducting complex applied statistical analyses using R packages, Python or other software tools. Experience with model building and algorithm development (which could include using Bayesian methods). Knowledge of modern computational statistics and/or machine learning approaches. Experience in High Performance Computing environments. Experience in managing staff and supervising students. Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks 3 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents. • http://www.ox.ac.uk/about_the_university/jobs/research/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that: • • As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy 4 Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 5
The Wellcome Trust Centre for Human Genetics
Are you looking for your next opportunity in research grant management? Are you seeking career progression in a friendly, supportive environment? We are recruiting Research Grant Managers to join the NDM Grant Management Team, working alongside researchers at the leading edge of science in the largest medical department at Oxford. The role of the Research Grants Manager is a key position within the NDM Grant Management Team, and our key objective is to provide an outstanding professional service to manage the cradle-to-grave process of research. Reporting to the Deputy Head of Grant Management (DHoGM), you will manage an assigned portfolio of research projects, ensuring that the needs of the academics and professional services, and the requirements of research funders, are met. You will benefit from being in an environment of specialists, supporting your own growth and development, with an opportunity to effect changes to processes which will ensure delivery of consistent, high quality, professional project support in research grant management. It is essential that you are educated to degree level or equivalent together with related experience, ideally in the higher education sector or research environment. You will have knowledge of the major funding bodies, and of current issues affecting the research funding sector. You will have demonstrable skills in effective people management and the ability to support, develop and motivate staff. Additionally, you will have excellent numeracy skills, a high level of accuracy, and attention to detail. Prior experience of Oracle Financials software or other financial software is highly desirable. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a permanent contract. Only applications received before 12 midday on Monday 12 May 2025 will be considered. Please quote 179385 on all correspondence.
Standard Grade 8: Research Grade 8: £48,235 - £57,255 with a discretionary range to £64,228 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata).
We have an exciting opportunity for a Postdoctoral Research Assistant in Quantitative Spatial Data Analysis for Colorectal Precancer to join the multidisciplinary GO-PRECISE colorectal precancer team based at the Nuffield Department of Medicine, University of Oxford. GlaxoSmithKline and Oxford University (GO) launched the PRECISE Alliance (Pre-Cancer Biology and Immunoprevention) in 2024, with the aim of conducting deep exploration of cancer precursors (precancers) to identify their molecular vulnerabilities and developing methods to intercept them. The alliance is directed by Professor Sarah Blagden. This post is within the colorectal precancer theme which is jointly led by Simon Leedham and David Church. You will be responsible for managing your own academic research and administrative activities, and adapting existing mathematical and statistical methods for analysis of high-dimensional imaging data, and developing new ones. Other responsibilities will include analysing quantitative imaging data from a variety of sources, including Spatial Transcriptomics and multiplex Spatial Proteomics platforms and developing skills in computational biology and mathematical spatial analysis via independent study and training courses. It is essential that you hold a PhD/DPhil (or close to completion) in mathematics, statistics, physics, engineering, data science or a related discipline, and have demonstrated ability to analyse and interpret complex multidimensional data. Experience of programming in Python, or demonstrated ability to rapidly acquire fluent knowledge of new programming languages, libraries, and platforms is essential for this role, along with a strong interest in interdisciplinary research in the biological and medical sciences. Experience of applying software engineering best practices and experience of working with biomedical datasets, particularly cancer data and/or spatial data would be highly desirable for this position. Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV, and 2 referees as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a fixed term contract until 31 December 2027 and is funded by GlaxoSmithKline. Only applications received before 12 midday on 12 May 2025 will be considered. Please quote 178283 on all correspondence.
We are seeking to appoint a highly motivated Postdoctoral Researcher with expertise in innate immune responses to cancer, in vivo/in vitro experimental models, and advanced molecular techniques to join the group at Ludwig Institute for Cancer Research. This position offers an exciting opportunity to lead innovative projects at the intersection of epigenetics and tumour immunology. By leveraging advanced functional genomics, transcriptomics, and proteomics approaches, you will develop novel therapeutic strategies for cancer immunotherapy. You will be responsible for managing your own academic research and administrative activities. You will design and conduct experiments to investigate the role of epigenetic factors in innate immune response regulation. Your work will involve disease modelling, including murine in vivo models, as well as in vitro studies using primary in-vivo and patient samples. You will apply flow cytometry to monitor immune responses and utilize next- generation sequencing technologies for deep molecular insights. Additionally, you will present your findings at national and international conferences, mentor junior researchers in the lab, and contribute to high-impact publications in top-tier scientific journals. It is essential that you hold a PhD/DPhil (or close to completion) in tumour immunology or a related life science field together with background in cancer research. You will also have experience in vivo/in vitro experimental models, functional genomics (CRISPR, shRNA), molecular biology. You will possess a strong skills in decision-making, problem-solving, planning and organising analysis and research. Experience with PDX models and primary leukemic cells is highly desirable. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract until 36 months and is funded by Ludwig. Only applications received before 12 midday on Thursday 29 May 2025 will be considered. Please quote **179087** on all correspondence.
Ludwig Institute for Cancer Research, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ
email
OxPoints
Senior Postdoctoral Researcher - Computational
preferred label
THIS IS A RE ADVERTISMENT PREVIOUS APPLICANTS NEED NOT APPLY We are looking for a Trial Manager to join the Oxford Respiratory Trials Unit for maternity leave cover. This post is also being offered as a 1 year secondment opportunity. The Trial Manager will be responsible for planning and overseeing the set up and management of a variety of studies conducted at ORTU and providing support to the Senior Trial Manager. This post requires someone who can work both as a member of a multi-disciplinary team and independently, using their initiative to seek solutions to problems and provide excellent administrative support. You will be responsible for the day-to-day management of ORTU studies - supporting Chief Investigators, Trial Assistants and Assistant Trial Managers in applying for regulatory approvals for trials including MHRA, ethics, HRA and Research & Development (R&D) approvals. You will also be responsible for organising team meetings, answering and resolving queries on trial conduct. In this post you will maintain oversight of the overall conduct and performance of studies within the portfolio. This will include predicting, identifying and resolving problems that are critical to the conduct of studies managed by the ORTU and planning to strategically avoid them. You will also have the opportunity contribute to the CTU quality management system, reviewing and writing SOPs and developing procedural documentation, as applicable. There will be opportunity for some hybrid office/remote working in line with department guidance e.g one to two days at home depending on working hours/pattern. The Unit has a core office day on a Thursday. About You Applicants should be educated to degree level in a relevant subject or have considerable experience in the set-up and ongoing monitoring and management of large complex multi-site clinical trials. You will also need to demonstrate that you have: • Good communication skills (oral and written), confident and articulate, and able to work across professional team and organisational boundaries to deliver training and work well with staff at all levels. • A range of IT skills (Word, Excel, PowerPoint, Outlook,) as demonstrated in part by your application. • Experience of writing Standard Operating Procedures, Trial Specific Procedures and working within a Quality Management System. • Experience of planning and progressing work activities using own initiative without supervision, prioritising own schedule and that of others, dividing time between projects appropriately. • Thorough knowledge of the regulatory and governance requirements for UK clinical trials – including submission of applications to these bodies. Having had previous experience in a respiratory trial setting and experience of CTIMP and Device Trials are both desirable capabilities for this post. About the Nuffield Department of Clinical Medicine The Nuffield Department of Clinical Medicine (NDM) is one of the largest departments of the University of Oxford and is part of the Medical Sciences Division, with responsibility for a significant part of the teaching of clinical students within the Medical School. Benefits of working University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits Application Process Please contact Emma Hedley emma.hedley@ndm.ox.ac.uk or Ellie Daly ellie.daly@ndm.ox.ac.uk for more details. The post is full time and fixed term to cover maternity leave for 12 months and is available from June 2025. This role can also be a secondment opportunity. Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Only applications received before 12:00 midday on Thursday 15th May 2025 will be considered.
NMD Experimental Medicine, Peter Medawar Building, Oxford
License
We have a fantastic opportunity for an experienced and motivated individual to join our forward-thinking Department as our Head of Communications. Responsible for the strategic oversight of the Nuffield Department of Medicine’s (NDM) internal and external communications, you will refresh and implement the communications strategy with a specific focus on strengthening internal comms across the different NDM units. The Head of Communications for NDM will have an expert understanding of the Higher Education communications field and will be expected to understand the context and scope of the communications required by a very large world-leading research department, engaging proactively internally and externally, to generate all forms of communication. Translating and targeting messages to a wide variety of audiences will be key. You will be expected to identify and implement the use of contemporary communication tools and services, in order to professionalise communications across and beyond the Department. As part of the role, you will be responsible for all departmental communication tools and channels, ensuring content is timely, accurate, relevant and creatively executed, whilst delivering a high level of service. This is a challenging role requiring excellent skills in stakeholder engagement, strategic thinking, operational communications and networking. You will work largely independently, and will need to relate to staff at all levels, maintaining confidence, tact and diplomacy in complex situations. To be successful in this role, you will educated to degree level in a relevant subject or come with equivalent experience in a higher education or science communications role, including public relations, media management and outreach. Significant and demonstrable ability to conceive, implement and evaluate both creative and successful communications strategies in a large and complex organisation with multiple stakeholder groups will be crucial to this role. You will of course come armed with excellent written skills, with the ability to develop high quality, accurate and consistent communications materials, including about scientific matters both internally and externally. You will be a self-directed strategic thinker with the capacity to problem-solve, take initiative, set priorities and exercise good judgment and deliver clear messages. The Nuffield Department of Medicine is a world-leading medical sciences research institute at the University of Oxford, working across several clinical disciplines. NDM is friendly, welcoming and keen to engage with the many challenges and opportunities that arise in our internationally recognised department. This role offers the opportunity to thrive in a diverse role in a supported environment. Applications for this vacancy should be made online and you will be need to upload a supporting statement and CV as part of your online application. Your supporting statement should explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a permanent contract. Only applications received before 12 midday on 16th May 2025 will be considered. Interviews will be held during week commencing 26th May. Please quote179340 on all correspondence.
About the Role The post holder will be based within the Modernising Medical Microbiology (MMM) Unit in Experimental Medicine division of the Nuffield Department of Medicine, working on infectious disease with a focus on fungal disease. Areas of research might include but are not limited to fungal genomics, fungal disease and climate change, AMR and novel approaches to drug development, the immune response to fungal infections, anti-fungal vaccine development. The post holder will be expected to attract external funding for their research. The successful applicant will be joining a new program at the University of Oxford on Fungal Biology in Human Health and Disease, funded by Oxford’s Strategic Research Fund, and involving in addition to the NDM, the Department of Biology and the AMR group (the Ineos Oxford Institute). The post holder will join a rich environment within MMM, including a strong partnership with colleagues in the Oxford University Hospital the Vaccine Research Group, the Jenner Institute, the Pandemic Sciences Institute, the three linked Wellcome Programmes in Kenya, Vietnam and Thailand, and the Ellison Institute in Oxford. About You You should; • Hold a medical degree - Bachelor of Medicine, Bachelor of Surgery (MBBS) or equivalent • Hold a CCT in infectious disease or clinical microbiology and be on the specialist register of the GMC and have a licence to practice in the UK • Hold or be in a position to secure an honorary contract with the OUH NHS trust (or agreed suitable alternative trust) • Demonstrable research experience, with the ability to develop an understanding of complex problems and apply in-depth knowledge to address these • Excellent interpersonal skills and the ability to credibly engage with a range of people across Oxford medicine About the Nuffield Department of Clinical Medicine The Nuffield Department of Clinical Medicine (NDM) is one of the largest departments of the University of Oxford and is part of the Medical Sciences Division, with responsibility for a significant part of the teaching of clinical students within the Medical School. Benefits of working University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits Application Process This position is an open ended externally funded position. Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Only applications received before 12:00 midday on Friday 16 May 2025 will be considered.
Nuffield Department of Medicine Strategic
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The Oxford-GSK Institute of Molecular & Computational Medicine has a new and exciting opportunity for a Postdoctoral Researcher, specialising in Neuronal Dysfunction in Alzheimer’s Disease, to join the Institute. The Institute is built around Fellows and Oxford-GSK project teams located across different departments within the Medical Sciences Division. Projects will initially focus on neurodegeneration and the central nervous system, specifically Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis but it is anticipated the range of activities will expand into other research areas in future. Based within the group of Dr Hugo Fernandes at the Department of Physiology, Anatomy and Genetics, you will be responsible for designing, validating, troubleshooting, and performing relevant assays to interrogate dysregulation induced in iPS-neurons by exposure to material from Alzheimer’s brains. You will develop an iPS-neuronal-microglial co-culture screening platform that can assess synaptic function and synaptic loss, and keep meticulous, detailed records of your work and commit to engaging with cloud-based analyses on the IMCM data platform. Other duties will include collaborating with peer scientists from cross-functional teams to analyse and interpret large complex datasets and communicate findings, and promoting the Oxford-GSK IMCM locally and nationally and disseminating research outcomes to advance knowledge in the specialist area. It is essential that you hold a PhD/DPhil (or close to completion) in biochemistry, molecular biology, neuroscience or a related field, and have experience in cell culture, preferably human pluripotent stem cells. You will have knowledge of neurodegenerative diseases, such as Alzheimer’s Disease, and of differentiation of iPSCs into neuronal and glial cultures. Experience in molecular biology methodologies, following and adapting protocols and setting up cellular assays including image-based is essential for this role, and knowledge of neuroinflammation would be highly desirable. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract until 30 September 2027 and is funded by GSK. Interviews will be held on 4 June 2025. Only applications received before 12 midday on 22 May 2025 will be considered. Please quote 179348 on all correspondence.
Ludwig Institute for Cancer Research, Old Road Campus Research Building, Oxford, OX3 7DQ
Research Grade 8: Research Grade 8: Salary in range £48,235 - £51,059 per annum (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata).
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Pandemic Science Institute, Li Ka Shing Centre for Health and Information Discovery, Old Road Campus, Headington, Oxford, OX3 7LF
Offices of the Nuffield Professor of Medicine, Old Road Campus
address
Job title Research Assistant - AVATAR Division Medical Sciences Department Nuffield Department of Medicine Location Ludwig Institute for Cancer Research, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ Grade and salary Research Grade 6: £34,982 - £40,855 with a discretionary range to £45,628 p.a. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year. Hours Full time Contract type Fixed-term contract until 31 March 2026 Funding is provided by the Biomedical Research Centre Reporting to Dr Richard Owen, Group Leader Vacancy reference 179039 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship under UK Visas and Immigration legislation, but eligibility will depend on the chosen candidate’s details so, if a visa is required, this will be determined once the selection has been completed. About us    What we offer https://hr.admin.ox.ac.uk/staff-benefits  An excellent contributory pension scheme  38 days annual leave  A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata)  A comprehensive range of childcare services  Family leave schemes  Cycle loan scheme  Discounted bus travel and Season Ticket travel loans  Membership to a variety of social and sports clubs  A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - www.ox.ac.uk/ludwig Research topic Oesophageal cancer biology and therapy response Principal Investigator / supervisor Dr Richard Owen Project team Richard Owen, Eric O’Neill, Elsita Jungkurth, Ethan Wang, Priyanka Jhangiani Project web site Richard Owen — Ludwig Cancer Research Funding partner The funds supporting this research project are provided by the Biomedical Research Centre Recent publications Hughes et al. Development of human pancreatic cancer avatars as a model for dynamic immune landscape profiling and personalized therapy. Sci Adv. 2024 Jul 5;10(27):eadm9071. Carroll et al. Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma. Cancer Cell. 2023 Jul 10;41(7):1222-1241.e7. The role We are seeking an enthusiastic and highly motivated Research Assistant to join the Owen lab to work within the Ludwig Institute for Cancer Research at the University of Oxford. This pioneering project focuses on characterising patient-derived oesophageal and gastric cancer tissues as part of prospectively approved clinical trials and developing personalised models understand therapy response characteristics. This is a unique opportunity to work in a tissue-focused translational research group aiming to enhance oesophageal cancer cure in a collaborative and highly clinically relevant way. Responsibilities will include collection, processing, maintenance and characterisation of tumour and blood samples in a perfused culture system developed and supervised by the O’Neill lab. This work will support the validation of targets identified in existing trial work to predict excellent patient outcomes with emerging therapies, and support studies of cancer detection and monitoring. You will be based primarily in the Old Road Campus Research Building, with responsibilities also requiring retrieval of human tissue samples from operating theatres at the Churchill Hospital. As a key member of the Owen and O’Neill labs, you will work closely with clinicians, scientists, and industry collaborators to advance this ambitious research programme. Responsibilities You will:      Be responsible for Human Tissue Handling & Processing: Retrieval, tracking, and processing of tumour samples from hospital departments. Establish and maintain 3D patient-derived AVATAR models. Contribute to wider project planning and adapt experimental protocols. Determine the most appropriate methodologies to test hypotheses Perform molecular biology and immunological assays, including immunohistochemistry, PCR, and flow cytometry. 1       Contribute to scientific reports and journal articles and the presentation of data/papers Assist with data collection, interpretation, and presentation of results at lab meetings and external collaborations. Liaise with clinicians, researchers, and industry partners to ensure accurate sample tracking and integration of findings into the wider research objectives. Ensure compliance with health and safety procedures, maintain research documentation, and contribute to general laboratory upkeep. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Job descriptions can never be comprehensive and you may be required to undertake other similar tasks and responsibilities. 2 Selection criteria Essential       A degree in biomedical sciences, molecular biology, cancer biology, or a related discipline. Experience in molecular and cellular biology techniques, such as immunohistochemistry, and flow cytometry. Strong organisational and record-keeping skills. Ability to work both independently and as part of a multidisciplinary team. Excellent communication skills, with the ability to liaise effectively with clinicians, researchers, and collaborators. Willingness to handle and process human tissue samples in compliance with ethical and regulatory guidelines. Desirable     A Master’s degree or equivalent experience in a relevant research field. Prior experience working with cell culture. Knowledge of cancer immunology. Experience in image analysis software. Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows:      Lone Working Work in hot or cold environments Working with blood, human products and human tissues Work in clinical areas with direct contact with patients (NOT administrative roles) Work with any substance which has any of the following pictograms on their MSDS:  Travel outside of Europe or North America on University Business 3 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents.  http://www.ox.ac.uk/about_the_university/jobs/research/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that:   As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates 4 Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 5
We have an exciting opportunity for a Postdoctoral Research Assistant in Quantitative Spatial Data Analysis for Colorectal Precancer to join the multidisciplinary GO-PRECISE colorectal precancer team based at the Nuffield Department of Medicine, University of Oxford. GlaxoSmithKline and Oxford University (GO) launched the PRECISE Alliance (Pre- Cancer Biology and Immunoprevention) in 2024, with the aim of conducting deep exploration of cancer precursors (precancers) to identify their molecular vulnerabilities and developing methods to intercept them. The alliance is directed by Professor Sarah Blagden. This post is within the colorectal precancer theme which is jointly led by Simon Leedham and David Church. You will be responsible for managing your own academic research and administrative activities, and adapting existing mathematical and statistical methods for analysis of high-dimensional imaging data, and developing new ones. Other responsibilities will include analysing quantitative imaging data from a variety of sources, including Spatial Transcriptomics and multiplex Spatial Proteomics platforms and developing skills in computational biology and mathematical spatial analysis via independent study and training courses. It is essential that you hold a PhD/DPhil (or close to completion) in mathematics, statistics, physics, engineering, data science or a related discipline, and have demonstrated ability to analyse and interpret complex multidimensional data. Experience of programming in Python, or demonstrated ability to rapidly acquire fluent knowledge of new programming languages, libraries, and platforms is essential for this role, along with a strong interest in interdisciplinary research in the biological and medical sciences. Experience of applying software engineering best practices and experience of working with biomedical datasets, particularly cancer data and/or spatial data would be highly desirable for this position. Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV, and 2 referees as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a fixed term contract until 31 December 2027 and is funded by GlaxoSmithKline. Only applications received before 12 midday on 12 May 2025 will be considered. Please quote **178283** on all correspondence.
179039 - Research Assistant - AVATAR - JD
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Are you looking for your next opportunity in research grant management? Are you seeking career progression in a friendly, supportive environment? We are recruiting Research Grant Managers to join the NDM Grant Management Team, working alongside researchers at the leading edge of science in the largest medical department at Oxford. The role of the Research Grants Manager is a key position within the NDM Grant Management Team, and our key objective is to provide an outstanding professional service to manage the cradle-to-grave process of research. Reporting to the Deputy Head of Grant Management (DHoGM), you will manage an assigned portfolio of research projects, ensuring that the needs of the academics and professional services, and the requirements of research funders, are met. You will benefit from being in an environment of specialists, supporting your own growth and development, with an opportunity to effect changes to processes which will ensure delivery of consistent, high quality, professional project support in research grant management. It is essential that you are educated to degree level or equivalent together with related experience, ideally in the higher education sector or research environment. You will have knowledge of the major funding bodies, and of current issues affecting the research funding sector. You will have demonstrable skills in effective people management and the ability to support, develop and motivate staff. Additionally, you will have excellent numeracy skills, a high level of accuracy, and attention to detail. Prior experience of Oracle Financials software or other financial software is highly desirable. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a permanent contract. Only applications received before 12 midday on Monday 12 May 2025 will be considered. Please quote **179385** on all correspondence.
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**About the Role** The post holder will be based within the Modernising Medical Microbiology (MMM) Unit in Experimental Medicine division of the Nuffield Department of Medicine, working on infectious disease with a focus on fungal disease. Areas of research might include but are not limited to fungal genomics, fungal disease and climate change, AMR and novel approaches to drug development, the immune response to fungal infections, anti-fungal vaccine development. The post holder will be expected to attract external funding for their research. The successful applicant will be joining a new program at the University of Oxford on Fungal Biology in Human Health and Disease, funded by Oxford’s Strategic Research Fund, and involving in addition to the NDM, the Department of Biology and the AMR group (the Ineos Oxford Institute). The post holder will join a rich environment within MMM, including a strong partnership with colleagues in the Oxford University Hospital the Vaccine Research Group, the Jenner Institute, the Pandemic Sciences Institute, the three linked Wellcome Programmes in Kenya, Vietnam and Thailand, and the Ellison Institute in Oxford. **About You** You should; • Hold a medical degree - Bachelor of Medicine, Bachelor of Surgery (MBBS) or equivalent • Hold a CCT in infectious disease or clinical microbiology and be on the specialist register of the GMC and have a licence to practice in the UK • Hold or be in a position to secure an honorary contract with the OUH NHS trust (or agreed suitable alternative trust) • Demonstrable research experience, with the ability to develop an understanding of complex problems and apply in-depth knowledge to address these • Excellent interpersonal skills and the ability to credibly engage with a range of people across Oxford medicine **About the Nuffield Department of Clinical Medicine** The Nuffield Department of Clinical Medicine (NDM) is one of the largest departments of the University of Oxford and is part of the Medical Sciences Division, with responsibility for a significant part of the teaching of clinical students within the Medical School. **Benefits of working** University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits **Application Process** This position is an open ended externally funded position. Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Only applications received before 12:00 midday on Friday 16 May 2025 will be considered.
The NDM Grant Management Team are an ambitious and supportive group, delivering high quality, professional grant management support across a broad portfolio of research projects. As a Senior Grants Officer, working under the supervision of the Research Grant Manager, this position offers an excellent opportunity for career progression in Research Administration, working alongside researchers at the leading edge of science in the largest medical department at Oxford. You will assume full responsibility for a range of activities which support the financial and operational management of a significant and complex portfolio of research projects. You will play a central role in liaising with academic staff, central university services such as Research Services and Research Accounts, and external collaborators and funders. You will be expected to work closely with grant holders and Professional Services staff to maintain and develop an efficient research administration service. It is essential that you are educated to degree level or equivalent related experience, with knowledge of grants and/or contracts. You will have experience of financial administration, as well as experience of interpreting and applying financial policies. Your excellent interpersonal skills will give you the ability to use tact and discretion to build effective and cooperative working relationships with colleagues at all levels. The ability to work independently is key and you will have a systematic, thorough, and well-organised approach to work. A high level of self-motivation and the ability to thrive in a busy environment is a must, ensuring that research grants are managed effectively so that targets and deadlines are met. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a permanent contract. Please note that all shortlisted candidates will be invited for interview on the week commencing Monday 19th May 2025. Only applications received before 12 midday on Wednesday 14 May 2025 will be considered. Please quote **179104 **on all correspondence.
Oxford Respiratory Trials Unit, Churchill Hospital, Headington, Oxford
Job title Research Software Engineer Division Medical Sciences Department Nuffield Department of Medicine Location Centre for Human Genetics, Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN On occasion, Mathematical Institute, Andrew Wiles Building, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG Research Grade 8: £48,235 - £57,255 with a discretionary range to £64,228 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata). Grade and salary Whilst this role is a Grade 8 position, we would be willing to consider less experienced candidates who might be suitable for the role with adjusted duties to then be offered as an under fill at Grade 7: £38,674 – £46,913 per annum This would be discussed with applicants at interview/appointment where appropriate Hours Contract type Full time Fixed-term contract until 1 April 2027 Funding is provided by Cancer Research UK Reporting to Professor Simon Leedham and Professor Helen Byrne Vacancy reference 177742 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship or may be eligible for Global Talent Visa under UK Visas and Immigration legislation. About us    What we offer https://hr.admin.ox.ac.uk/staff-benefits  An excellent contributory pension scheme  38 days annual leave  A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata)  A comprehensive range of childcare services  Family leave schemes  Cycle loan scheme  Discounted bus travel and Season Ticket travel loans  Membership to a variety of social and sports clubs  A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit – www.chg.ox.ac.uk The role The Nuffield Department of Medicine have an exciting opportunity for a Research Software Engineer to work with Professor Simon Leedham, at the Centre for Human Genetics, and Professor Helen Byrne, at the Mathematical Institute University of Oxford. This is a 2-year fixed term position, funded by the Cancer Research UK Oxford Centre. The work will be jointly supervised by Professor Leedham, Professor Byrne and Dr Joshua Bull (Mathematical Institute). You will work as part of the Oxford Spatial Biology Group, a large multidisciplinary team of mathematicians, computational biologists, experimentalists and clinicians, and in collaboration with the research groups of Professors Leedham and Byrne and the Cancer Research UK Oxford Centre. You will support the development of our spatial biology software, MuSpAn. The generation of spatial data in biology has been transformed by multiplex imaging and spatial-omics technologies, such as single cell spatial transcriptomics. These approaches permit detailed mapping of phenotypic information about individual cells and their spatial locations within tissue sections. We have developed MuSpAn in order to analyse these complex imaging datasets. MuSpAn is a Python toolbox for multiscale analysis of spatial data, using techniques drawn from spatial statistics, topological data analysis and networks (www.muspan.co.uk). The aim of this project is to further develop MuSpAn, by extending the range of methods within the software, improving its performance, ensuring that new functionality adheres to best practices in software engineering, and producing training materials for new users. Responsibilities You will:          Design and implement high quality, reliable and maintainable software that will enable the translational impact of existing research. Collaborate with colleagues from the Mathematical Institute, Centre for Human Genetics, and Cancer Research UK Oxford Centre, to support the development and improvement of research software. Collaborate on the preparation of scientific reports and journal articles, present papers and posters at conferences/workshops. Follow and promote best practices for research software engineering and reproducible research within the University of Oxford and the wider UK and international research community. Train researchers within the University of Oxford on the effective use of software for research. Contribute to the development of training material for workshops and courses offered by the Spatial Biology Group. Contribute to community activities such as seminars and networking events. Develop skills in many areas of computational research and software development via independent study and training courses. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. 1 Selection criteria Essential          Hold a PhD/DPhil (or be close to completion) with a significant software development component Experience of software development in a research environment Demonstrated ability to implement and deploy a complex software engineering project. Experience in applying software engineering best practices (e.g. issue tracking, code review, testing, documentation and continuous integration). Substantial experience with Python, and with at least one lower level programming language (e.g C++). Experience integrating Python code with lower-level functionality (e.g., speeding up python packages using C or C++ backends) Demonstrated ability to rapidly acquire fluent knowledge of new programming languages, libraries, and platforms. Experience structuring large software projects using common software architecture paradigms (e.g. Object-orientated programming). Excellent communication skills, including the ability to communicate effectively with biomedical researchers, write for publication and present at meetings Desirable    Experience in one or more of the following: using hierarchical data formats to process large datasets (e.g., HDF5 files), development of graphical user interfaces, development of plug-ins for existing software. Experience of working with biological data, particularly cancer data. Background and/or interest in mathematics (for example, geometry, statistics, topology, network science). Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks 2 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents.  http://www.ox.ac.uk/about_the_university/jobs/research/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that:   As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates 3 Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 4
Job title Senior Operations and Programme Manager – Centre for Genomic Pathogen Surveillance Division Medical Sciences Department Nuffield Department of Medicine Location Pandemic Science Institute, Li Ka Shing Centre for Health and Information Discovery, Old Road Campus, Headington, Oxford, OX3 7LF Grade and salary Research Grade 9: £55,636 - £64,228 with a discretionary range to £72,079 per annum. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata). Hours Full time Contract type Fixed-term contract until 31 May 2027 Funding is provided by the National Institute for Health Research (NIHR) Reporting to David Aanensen, Senior Group Leader Vacancy reference 178959 Hybrid working arrangements The successful person will need to work on site for a minimum of 3 days per week Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship or may be eligible for Global Talent Visa under UK Visas and Immigration legislation. About us • • • What we offer https://hr.admin.ox.ac.uk/staff-benefits • An excellent contributory pension scheme • 38 days annual leave • A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata) • A comprehensive range of childcare services • Family leave schemes • Cycle loan scheme • Discounted bus travel and Season Ticket travel loans • Membership to a variety of social and sports clubs • A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - www.psi.ox.ac.uk The role This is an exciting opportunity for an experienced Senior Operations and Programme Manager to join the Centre for Genomic Pathogen Surveillance (CGPS) at the Pandemic Science Institute, Nuffield Department of Medicine. We are an organisation focussed on the upscaling and delivery of public health genomics for surveillance and mitigation of infectious diseases. You will bring an enthusiasm and appreciation for global health delivery and act as a lynchpin across projects and strategy for growth and delivery. You will take a lead in our key funded programme of work within the NIHR Global Health Research Unit (GHRU) on Genomic surveillance of AMR focused on country capacity for digital and genomic epidemiology and align strategy and approach with our WHO Collaborating Centre on genomic Surveillance of AMR. The role offers opportunity for development of strategy, programme management and delivery of impactful policy, translating science into implementation. Reporting to the Principal Investigator, Professor David Aanensen, you will be a key member of the senior team for CGPS with responsibility for leading on the delivery of a significant programme of activities across international collaborators and major public health institutions. You will take on the role of managing operations and liaising with teams within the University of Oxford to ensure smooth activity delivery within the group. Your main focus will be to manage the flagship NIHR Global Health Research Unit, which brings together a multi-disciplinary UK based team (CGPS) with lead researchers and international collaborating partners in the Philippines, Colombia, India and Nigeria. This collaboration is well established and has worked on capacity building and developing whole genome sequencing (WGS) for AMR embedded within national control programmes. This is being achieved through the development and rollout of technical support for laboratory, bioinformatics and institutional capacity as well as local and international pathogen surveys and subsequent analysis. We are currently focusing on developing and linking data solutions to operationalise genomics linked to the correct epidemiological and clinical data for priority AMR pathogens. Generating actionable data to enable policy makers and public health programmes to make informed decisions is crucial to effectively respond to AMR. You will be responsible for delivering on all aspects of project management across the project, both in the UK and across our international collaborators, to ensure that all consortium project deliverables are met, and to enable the CGPS to continue its mission of delivering real-world impact in global health. This will also entail cross-collaboration and input into other relevant activities within CGPS aligned to the group’s strategic vision. Another key aspect of this role is to support the coordination of our WHO Collaborating Centre deliverables, ensuring these are intertwined with the objectives and mission of CGPS and the GHRU project. About the CGPS Within CGPS (http://pathogensurveillance.net) we focus on pathogen dynamics, data flow and the use of genome sequencing for surveillance of microbial pathogens through a combination of web application and software engineering, combined with capacity building for technical, laboratory, financial and data management with global partners. CGPS works with major public health agencies such as the US CDC, the European CDC, UK Health Security Agency and the WHO, as well as research partners in Africa, Asia, Europe and the Americas, data is utilised to interpret and aid decision making for infection control. CGPS is a passionate team making a significant impact on global public health institutions, supporting its mission of delivering real-world impact in global health through driving innovation to support a global genomic pathogen surveillance network 1 Responsibilities You will: • • • • • • • • • • Lead a portfolio of multi-year scientific projects on behalf of the team: o Work collaboratively with the team of scientists, engineers and admin staff to oversee the effective delivery of project milestones within required timeframes and budget. o Manage the resourcing/recruitment requirements and effective drive and operational delivery of the CGPS strategy. o Strategically manage and develop the programme in order to meet scientific and public health goals and in line with organisational objectives. o Act as the key point of contact for programme enquiries and leading the investigation and resolution of complex and sensitive matters. o Ensure the work is conducted within the University and Funders’ standards and also within the terms and conditions. Manage a major, complex international project on behalf of the Principal Investigator(s): o Ensure all project work package activities are properly coordinated and that all scientific and non-scientific deliverables and milestones are met in a timely manner and within budget. o Be responsible for project and resource planning, identifying issues & risks and providing pragmatic solutions. o Maintain trusted relationships and coordinate project activities with research collaborators in the Philippines, Colombia, India and Nigeria. o Work and communicate both internally and externally with members of the CGPS team, collaborators, Oxford support teams including Research Services, Grants, Research Accounts and Finance teams, and the NIHR both in writing and orally. Act as the coordinator for our World Health Organisation Collaboration Centre. Work within the senior management team to direct a large (c25) multidisciplinary team including researchers, software developers, project, operational staff and consultants to ensure effective delivery of a strategically important programme of activities for both the University, genomic pathogen surveillance community and the wider Global Health community. Line manage and develop CGPS team members such as programme management and support staff. Establish and develop excellent working relationships with internal Oxford teams to enable effective programme delivery, including Research Services, Research Accounts, grants, finance, HR teams and Oxford University Innovation. Organise and chair meetings, committees and working groups related to the programme and play a leading role in growing external networks and cross-sector initiatives to benefit CGPS and the University. Carry out any other duties that may be reasonably required in line with the role and needs of the CGPS. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Job descriptions can never be comprehensive and you may be required to undertake other similar tasks and responsibilities. 2 Selection criteria Essential • • • • • • • Hold a post graduate degree with demonstrable experience in leading and managing complex scientific projects/programmes successfully, or educated to an undergraduate level with an excellent and extensive track record of leading and managing successful scientific projects/programmes. Ability to demonstrate leadership of a large and complex programme, for example, with multiple stakeholders, multi-disciplinary teams, multiple budgets, and regulatory complexity. Significant line management experience/ experience in managing cross-functional teams. Ability to think strategically and creatively to devise optimal solutions to complex problems. Highly organised with the ability to manage a vast amount of relatively complex information and to prioritise a demanding workload with competing deadlines. Ability to communicate research impact effectively to a high standard, including relatively complex scientific matters, orally and in writing. Strong interpersonal skills, to work efficiently in multidisciplinary teams and with a wide variety of people internationally. Desirable • • Understanding of the University research grant management procedures and/or previous relevant experience within the higher education sector. A certified Project or Programme Management Qualification (e.g. Prince 2). 3 Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • Travel outside of Europe or North America on University Business 4 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents. • http://www.ox.ac.uk/about_the_university/jobs/professionalandmanagement/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that: • • As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy 5 Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 6
178673 - Senior Postdoctoral Researcher - JD.pdf
177742 - Research Software Engineer- JD.pdf
Job title Postdoctoral Researcher - therapeutic strategies for reprogramming tumour-associated innate immune cells Division Medical Sciences Department Nuffield Department of Medicine Location Ludwig Institute for Cancer Research, Old Road Campus Research Building, Oxford, OX3 7DQ Grade and salary Research Grade 7: £38,674 - £46,913 with a discretionary range to £52,539 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata). Hours Full time Contract type Fixed-term contract for 36 months Funding is provided by Ludwig Reporting to Professor Yang Shi, Senior Group Leader Vacancy reference 179087 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship. About us    What we offer https://hr.admin.ox.ac.uk/staff-benefits  An excellent contributory pension scheme  38 days annual leave  A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata)  A comprehensive range of childcare services  Family leave schemes  Cycle loan scheme  Discounted bus travel and Season Ticket travel loans  Membership to a variety of social and sports clubs  A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - https://www.ludwig.ox.ac.uk The role We are seeking a highly motivated Postdoctoral Researcher with expertise in innate immune responses to cancer, in vivo/in vitro experimental models, and advanced molecular techniques. This position offers an exciting opportunity to lead innovative projects at the intersection of epigenetics and tumour immunology. By leveraging advanced functional genomics, transcriptomics, and proteomics approaches, you will develop novel therapeutic strategies for cancer immunotherapy. As a postdoc in our lab, you will design and conduct experiments to investigate the role of epigenetic factors in innate immune response regulation. Your work will involve disease modelling, including murine in vivo models, as well as in vitro studies using primary in-vivo and patient samples. You will apply flow cytometry to monitor immune responses and utilize next-generation sequencing technologies for deep molecular insights. Additionally, you will present your findings at national and international conferences, mentor junior researchers in the lab, and contribute to high-impact publications in top-tier scientific journals. Our lab provides a highly collaborative and stimulating research environment with access to cuttingedge technologies. We actively support career development, offering guidance on fellowship and grant applications to help you establish scientific independence. You will hold a PhD (or close to completion) in tumour immunology or a related life science field, with a strong background in vivo/in vitro experimental murine models, functional genomics (CRISPR, shRNA, siRNA), and molecular biology. Experience with advanced murine models and high-throughput sequencing methods (bulk and single-cell RNA sequencing) is highly desirable. If you are passionate about advancing the understanding of blood cancers, developing new therapeutic strategies, and expanding our discoveries, we invite you to apply and become part of our dynamic research team! Responsibilities You will:             Take participation in the Ludwig Cancer Research funded project led by Prof Shi, to investigate the role of epigenetic factors in innate immune response against cancer. Design and perform original research using murine in vivo models, as well as in vitro studies using primary in-vivo and patient samples. Manage own academic research and administrative activities. This involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines. Supervise and train junior staff in epigenetic techniques and molecular biology. Act as a source of information and advice to other members of the group. Operate laboratory equipment used for all aspects of cell/molecular biology/biochemistry. Interpret results and present them to senior members of the group and Prof Shi. Develop ideas for generating research income and new scientific techniques. Be responsible with others for the biological safety of the laboratory. Communicate with Prof Shi and other members of the group as required, ensuring that they are kept fully up to date with progress and any difficulties in the research project. Participate in and contribute directly to scientific discussions with other members of the research group and collaborators both on the project and contributing ideas for future research projects. Maintain confidentiality regarding research data when interacting with non-collaborating researchers. 1      Assist in dissemination of findings of the research group by authorship of manuscripts, presentation of results at meetings, and contribution to the group website. Collaborate in the preparation of scientific reports and journal articles and occasionally present papers and posters. Attend appropriate scientific seminars, training opportunities and meetings in the Institute and University. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Job descriptions can never be comprehensive and you may be required to undertake other similar tasks and responsibilities. Selection criteria Essential       PhD/DPhil (or close to completion) in tumour immunology or a related life science field. Background in cancer research. Expereince in vivo/in vitro experimental models, functional genomics (CRISPR, shRNA), molecular biology. Experience working with primary patient samples. Strong skills in decision-making, problem-solving, planning and organising analysis and research. Excellent communication skills, including the ability to write text that can be published, present data at conferences, and represent the research group at meetings. Desirable    Experience working with high-throughput sequencing methods, including bulk and single-cell RNA sequencing. Experience with PDX models and primary leukemic cells is highly desirable. First-author publication in an international journal. 2 Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows:        Lone Working Working with Ionising Radiation Working with category 3b or 4 lasers (laser safety class) Working with infectious pathogens (hazard group 2/3) - Hazard Group 3 pathogens Working with blood, human products and human tissues Work with allergens, Eg laboratory animals, pollen, dust, fish or insects etc. Work with any substance which has any of the following pictograms on their MSDS:  Regular manual handling Additional security pre-employment checks This job includes duties that will require additional security pre-employment checks:   A satisfactory basic Disclosure and Barring Service check University security screening (eg identity checks) 3 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents.  http://www.ox.ac.uk/about_the_university/jobs/research/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that:   As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates 4 Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 5
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Postdoctoral Researcher - therapeutic strategies for reprogramming tumour-associated innate immune cells
Job title Senior Grants Officer Division Medical Sciences Department Nuffield Department of Medicine Location NDM Operations, Grant Management Team, based at the Li Ka Shing Centre for Health Information and Discovery, Old Road Campus, Heading, Oxford, OX3 7LF Grade and salary Standard Grade 6: £34,982 - £40,855 with a discretionary range to £44,382 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata). Hours Full time Contract type Permanent Reporting to Research Grants Manager Vacancy reference 179104 Hybrid working arrangements The successful person will need to work on site for a minimum of 3 days per week Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship. About us   What we offer https://hr.admin.ox.ac.uk/staff-benefits  An excellent contributory pension scheme  38 days annual leave  A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata)  A comprehensive range of childcare services  Family leave schemes  Cycle loan scheme  Discounted bus travel and Season Ticket travel loans  Membership to a variety of social and sports clubs  A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk The role We are seeking to appoint a Senior Grants Officer to join the NDM Grant Management Team, which delivers high quality, professional project support. The role of the Senior Grants Officer is a key position within the NDM Grant Management Team, and whilst you will report to and work under the general direction of the Research Grants Manager, you will be responsible for your own work on a day-to-day basis. The ability to work independently with minimal supervision is essential. This position offers an excellent opportunity for career progression in Research Administration, working alongside researchers at the leading edge of science in the largest medical department at Oxford. You will assume full responsibility for a range of activities which support the financial and operational management of the project portfolio. You will play a central role in liaising with academic staff, central university services such as Research Services and Research Accounts, and external collaborators and funders. You will be expected to work closely with grant holders and Professional Services staff, to maintain and develop an efficient research administration service. The project portfolio has a diverse range of funders, and strong links with industry, and collaborates on research with a large number of other institutions. The complexity and variety require the skills and confidence to juggle conflicting priorities and deadlines. You will have strong organisational and interpersonal skills with a high level of self-motivation, and the ability to thrive in a busy environment to ensure that the Department’s research grant applications and awards are managed effectively so that targets and deadlines are met. Responsibilities You will: Research Awards Process (pre and post award)        Manage day to day pre-award activities, including preparation of, and accurate costings for, grant applications using the University’s costing tool (currently X5). You will ensure compliance with funder terms and conditions and provide advice and support to grant holders and researchers in the preparation of funder applications, working with them to complete funder application forms and liaising with external funders as appropriate. Be responsible for ensuring that grant applications and/or amendments are submitted to Research Services on a timely basis to meet service deadlines. You will check that they are accurate, comply with funder terms and conditions, and have the necessary supporting documentation. Bring any matching funding, underwrites required/requested, or other requirements that are likely to have a significant impact on the Department to the attention of Professional Services staff in good time. Oversee the financial administration of a significant and complex portfolio of research projects working closely with Professional Services staff, Project Managers, and grant holders (who remain accountable for managing their grants). You will check research budget set-ups for accuracy on Oracle, interpreting and implementing University procedures. You will deal with issues arising, analysing grant spend on a monthly basis, highlighting variances and taking follow-up action. Liaise with research groups and Professional Services staff, includingHR where relevant, regarding posts on grants to ensure that funding is available before recruitment processes are undertaken. Meet routinely with all of the grant holders within the portfolio to review their financial position and provide problem-solving advice while ensuring that the project will remain compliant with terms and conditions (including robustness under audit scrutiny). Escalate any concerns with the Research Grants Manager as soon as possible. Liaise with external funders, as required, and maintain an up-to-date knowledge of major funding bodies’ terms and conditions. 1       Work with Research Accounts to prepare annual and final statements of expenditure, ensuring that expenditure is appropriately allocated to research projects, and monitored in line with budgets and in accordance with University policies and the funder terms and conditions. Seek grant management approval from the Research Grant Manager ahead of sign off. Coordinate and collate data required for audits on research awards and liaise with Research Accounts on any audit queries, discussing with the Professional Services staff where required. Ensure that grant holders, Professional Services staff, and Project Managers are provided with monthly project reports, highlighting variances and taking follow-up action as required following discussions. Liaise with other Oxford departments and external institutions where a grant holder is a collaborator/partner on a project to ensure the correct budget is transferred to collaborator institutions and that appropriate mechanisms are in place to report on expenditure by collaborators. Co-ordinate with Research Services on the processing of research contracts, and ensure that all finalised documentation is circulated and filed appropriately. Provide support to other team members across the entire grant portfolio as required. Internal and external communication   Attend monthly grant management meetings, taking the lead role for planning, preparing and presenting financial reports, and analysing data on grant expenditure to share with the administration and research teams. Escalate issues that require the involvement of the Research Grants Manager or the Deputy Head of Grant Management in a timely manner. Training and Development   Support the training of Grants Officers and Apprentices within the Team on a day-to-day basis. Provide local training on the use of the University’s costing tool and Oracle financial system to new staff as appropriate (to complement centrally provided training). Information Management     Work closely with other colleagues to support the development of information management systems that meet the needs of the grant management team, grant holders, and University/funder reporting requirements. Maintain information on any relevant in-house systems. Follow Standard Operating Procedures in place for research administrative processes and work with senior colleagues to ensure they remain relevant. Ensure that all documentation relating to grants is up to date and available to the grant holder and Professional Services staff. Other responsibilities      Work with other colleagues to foster a positive team culture, and model core values and behaviours. Assist in forecasting and re-forecasting grant expenditure for budgeting purposes. Assist in relevant project activities and undertake other responsibilities commensurate with the grade of the post. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to take no more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. 2 Job descriptions can never be comprehensive and you may be required to undertake other similar tasks and responsibilities. Selection criteria Essential            Educated to a degree level or equivalent related experience. Knowledge of grants and/or contracts, preferably within the higher education sector. Experience of financial administration, as well as experience of interpreting and applying financial policies. High levels of accuracy and attention to detail when inputting data and providing information. Excellent inter-personal skills, including the ability to use tact and discretion to build effective and cooperative working relationships with colleagues at all levels. Team player who works well within a team but is also adept at working independently. Flexible and adaptable approach to work, with a proactive problem-solving attitude. Excellent IT skills for creating and managing information, including experience in the use of the Microsoft Office Suite, particularly Word, PowerPoint and Excel, and the ability to learn new systems. A systematic, thorough, and well-organised approach with the ability to work to deadlines and prioritise tasks. A high level of numeracy and confidence in dealing with financial data, with the ability to analyse and understand that data. Experience of using a costing tool for grant applications, contracts, or projects. Desirable    Experience of Oracle Financials software or other financial software. Experience of the University’s costing and pricing tool, X5. Experience of working with industry partners and collaborators. 3 Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows:   Regular manual handling Travel outside of Europe or North America on University Business 4 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents.  http://www.ox.ac.uk/about_the_university/jobs/professionalandmanagement/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that:   As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates 5 Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 6
Centre for Human Genetics, Building for Genomic Medicine, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7BN
Standard Grade 6: Standard Grade 6: £34,982 - £40,855 with a discretionary range to £44,382 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata).
We are seeking an enthusiastic and highly motivated Research Assistant to join the Owen lab to work within the Ludwig Institute for Cancer Research at the University of Oxford. This pioneering project focuses on characterising patient-derived oesophageal and gastric cancer tissues as part of prospectively approved clinical trials and developing personalised models understand therapy response characteristics. This is a unique opportunity to work in a tissue-focused translational research group aiming to enhance oesophageal cancer cure in a collaborative and highly clinically relevant way. Your role will also involve handling and processing human tissue samples, establishing and maintaining 3D patient-derived AVATAR models, and performing a range of molecular biology and immunological assays such as immunohistochemistry, PCR, and flow cytometry. You will assist with data collection, interpretation, and the presentation of findings at lab meetings and to external collaborators, while liaising closely with clinicians, researchers, and industry partners. Additionally, you will ensure compliance with health and safety protocols, maintain accurate research documentation, and support the general upkeep of the laboratory. It is essential that you hold a degree in biomedical sciences, molecular biology, cancer biology, or a related discipline, and have hands-on experience with molecular and cellular biology techniques such as immunohistochemistry and flow cytometry. You should possess strong organisational and record-keeping skills, be comfortable working both independently and as part of a multidisciplinary team, and have excellent communication skills to liaise effectively with clinicians, researchers, and collaborators. A willingness to handle and process human tissue samples in line with ethical and regulatory guidelines is also required. In addition, it would be desirable for you to hold a Master’s degree or have equivalent experience in a relevant research field, along with prior experience working with cell culture, knowledge of cancer immunology, and familiarity with image analysis software. Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract until 31 March 2026 and is funded by the BRC. Only applications received before 12 midday on 4 June 2025 will be considered. Please quote 179039 on all correspondence.
NDM Experimental Medicine, John Radcliffe Hospital, Oxford
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Li Ka Shing Centre for Health Information and Discovery
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Senior Postdoctoral Researcher in Application of AI for Medicine (4 posts)
179087 - Postdoctoral Researcher - JD.pdf
Postdoctoral Research Assistant in Quantitative Spatial Data Analysis for Colorectal Precancer
We have a fantastic opportunity for an experienced and motivated individual to join our forward-thinking Department as our Head of Communications. Responsible for the strategic oversight of the Nuffield Department of Medicine’s (NDM) internal and external communications, you will refresh and implement the communications strategy with a specific focus on strengthening internal comms across the different NDM units. The Head of Communications for NDM will have an expert understanding of the Higher Education communications field and will be expected to understand the context and scope of the communications required by a very large world-leading research department, engaging proactively internally and externally, to generate all forms of communication. Translating and targeting messages to a wide variety of audiences will be key. You will be expected to identify and implement the use of contemporary communication tools and services, in order to professionalise communications across and beyond the Department. As part of the role, you will be responsible for all departmental communication tools and channels, ensuring content is timely, accurate, relevant and creatively executed, whilst delivering a high level of service. This is a challenging role requiring excellent skills in stakeholder engagement, strategic thinking, operational communications and networking. You will work largely independently, and will need to relate to staff at all levels, maintaining confidence, tact and diplomacy in complex situations. To be successful in this role, you will educated to degree level in a relevant subject or come with equivalent experience in a higher education or science communications role, including public relations, media management and outreach. Significant and demonstrable ability to conceive, implement and evaluate both creative and successful communications strategies in a large and complex organisation with multiple stakeholder groups will be crucial to this role. You will of course come armed with excellent written skills, with the ability to develop high quality, accurate and consistent communications materials, including about scientific matters both internally and externally. You will be a self-directed strategic thinker with the capacity to problem- solve, take initiative, set priorities and exercise good judgment and deliver clear messages. The Nuffield Department of Medicine is a world-leading medical sciences research institute at the University of Oxford, working across several clinical disciplines. NDM is friendly, welcoming and keen to engage with the many challenges and opportunities that arise in our internationally recognised department. This role offers the opportunity to thrive in a diverse role in a supported environment. Applications for this vacancy should be made online and you will be need to upload a supporting statement and CV as part of your online application. Your supporting statement should explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a permanent contract. Only applications received before **12 midday on 16th May 2025** will be considered. Interviews will be held during week commencing 26th May. Please quote **179340** on all correspondence.
Is Part Of
Research Grade 7: Research Grade 7: £38,674 - £46,913 with a discretionary range to £52,539 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata)
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Research Grade 7: Research Grade 7: Salary in range £38,674 - £46,913 per annum.
We have an exciting opportunity for a Research Software Engineer to join the Centre for Human Genetics at the Nuffield Department of Medicine. You will be working closely with Professor Simon Leedham and Professor Helen Byrne at the Mathematical Institute University of Oxford. You will work as part of the Oxford Spatial Biology Group, a large multidisciplinary team of mathematicians, computational biologists, experimentalists and clinicians, and in collaboration with the research groups of Professors Leedham and Byrne and the Cancer Research UK Oxford Centre. You will support the development of our spatial biology software, MuSpAn. You will be responsible for designing and implementing high quality, reliable and maintainable software that will enable the translational impact of existing research. You will be collaborating with colleagues from the Mathematical Institute, Centre for Human Genetics, and Cancer Research UK Oxford Centre, to support the development and improvement of research software. You will train researchers within the University of Oxford on the effective use of software for research, contribute to the development of training material for workshops and courses offered by the Spatial Biology Group. It is essential that you hold a PhD/DPhil (or are close to completion) with a significant software development component, and have experience of software development in a research environment. You will also have experience of applying software engineering best practices (e.g. issue tracking, code review, testing, documentation and continuous integration). Demonstrated ability to rapidly acquire fluent knowledge of new programming languages, libraries, and platforms is essential, along with experience integrating Python code with lower-level functionality (e.g., speeding up python packages using C or C++ backends). You will have excellent communication skills, including the ability to communicate effectively with biomedical researchers, write for publication and present at meetings. Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This position is offered full time on a fixed term contract until 1 April 2027 and is funded by CRUK. Only applications received before 12 midday on Thursday 29 May 2025 will be considered. Please quote **177742** on all correspondence.
177230 - Senior Postdoctoral Researcher - JD
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Job title Head of Communications - NDM Division Medical Sciences Department Nuffield Department of Medicine Location Offices of the Nuffield Professor of Medicine, Henry Wellcome Building, Headington, Oxford OX3 7BN Grade and salary Standard Grade 9: £55,636 - £64,228 with a discretionary range to £70,029 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata). Hours Full time Contract type Permanent Funding is provided by the Department Reporting to NDM Chief of Staff Vacancy reference 179340 Hybrid working arrangements The successful person will need to work on site for a minimum of 3 days per week Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship under UK Visas and Immigration legislation, but eligibility will depend on the chosen candidate’s details so, if a visa is required, this will be determined once the selection has been completed. About us • • What we offer https://hr.admin.ox.ac.uk/staff-benefits • An excellent contributory pension scheme • 38 days annual leave • A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata) • A comprehensive range of childcare services • Family leave schemes • Cycle loan scheme • Discounted bus travel and Season Ticket travel loans • Membership to a variety of social and sports clubs • A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk The role The Head of Communications is responsible for the strategic oversight of the Nuffield Department of Medicine’s (NDM) internal and external communications. Reporting to the Chief of Staff, you will refresh and implement the communication strategy with a specific focus on strengthening internal communications across the different NDM units. The strategy will strengthen information sharing and raise awareness of the goals and achievements of NDM across the Department, Division, University and wider research communities, seeking to support the Head of Department’s strategic vision for NDM with targeted and meaningful communications. The Head of Communications for NDM will have an expert understanding of the Higher Education communications field and will be expected to understand the context and scope of the communications required by a very large world-leading research department, engaging proactively internally and externally, to generate all forms of communication. Translating and targeting messages to a wide variety of audiences will be key. You will be expected to identify and implement the use of contemporary communication tools and services, in order to professionalise communications across and beyond the Department. As part of the role, you will be responsible for all departmental communication tools and channels, ensuring content is timely, accurate, relevant and creatively executed, whilst delivering a high level of service. You will line manage the NDM Communications Team, currently consisting of three team members. Furthermore, you will provide support and leadership to the network of existing externally funded departmental communication staff, inducting all new communications staff and ensuring their activities are in line with policy and best practice in order to maintain the Departments stature and reputational integrity. You will work closely with senior departmental administrative staff and support staff within all Institutes, Centres and Units across NDM, and define and deliver the operational support service needed to deliver the Department’s communications strategy. Overall, contributing specialist advice, coordinating strategic planning in communications, implementing and monitoring the strategy you develop. You will need to build strong working relationships and maintain collaborative partnerships with contacts within the Medical Sciences Division (MSD) and with senior officers across the University, particularly with the Public Affairs Directorate (PAD). This is a challenging role requiring excellent skills in stakeholder engagement, strategic thinking, operational communications and networking. You will work largely independently, and will need to relate to staff at all levels, maintaining confidence, tact and diplomacy in complex situations. Responsibilities Strategic • • • Evaluate the communications strategy, channels and outputs, including analysing results, refreshing the strategy and implementing solutions where necessary, with a particular focus on internal communication considering audience requirements, channels, timescales and resources. Plan and deliver effective and timely departmental communications activity in line with this strategy. This will include writing and editing online materials (e.g. internal and external sections of the NDM website) and researching and composing scientific communications. Proactively market and promote the new NDM Education Strategy, across the Department/Division and University, using all appropriate media and communication channels. Proactively engage, internally and externally, to generate all forms of communication. 1 • • • • • • • Advise on the reorganisation of communication work within Departments Institutes, Centres and Units engaging with the local network of staff supporting this area already and including and overseeing any new posts to direct resource as required. Maintain an awareness of Divisional-wide policies in regard to digital technologies (e.g. web policy, social media guidelines, using e-newsletters etc.) and legislative compliance (e.g. Accessibility, GDPR, data protection), monitor these at departmental level and evaluate best practice with Departmental, Divisional and University colleagues Lead on high-profile communications for NDM, support NDM experts whilst engaging with the media e.g. (expert advice, coaching and presentations) and protect the department and organisation from reputational damage by taking a central role in crisis communications and damage control. Be responsible for ensuring NDM Branding (e.g. websites, logos, email signatures, document templates) is used consistently across all NDM Institutes, Centres and Units; considerate of the overarching University branding guidelines. Participate in Departmental or University committees, panels and groups as appropriate representing the department’s strategic interests. Provide individual support to the Head of Department and Chief Operating Officer as required. Advise the senior management of the department on communications risk and present strategies to mitigate those risks. Line Management • Responsible for the workload management and personal and professional development of the NDM Communications team. Partnerships • • • • • • Become a point of contact between NDM researchers and central/divisional communications teams for all communication matters. Establishing excellent working relationships with all parties including Central PAD and the MSD Head of Communications to ensure efforts are coordinated to best support our research and administrative teams. Working with Divisional and Central colleagues the post holder will support community engagement activities as appropriate. Participate in the Medical Sciences Division Communications Officers Network attending regular meetings, workshops and sharing best practice with others, and feeding back into the department where applicable. Build strong professional relationships with key communications stakeholders across the collegiate University to enable changes in current practice to be delivered that fully embrace NDM and its complex, broad and far-reaching research activity. Ensure external communications activity is coordinated and streamlined to reflect Department strategies and aims whilst it is fairly and accurately acknowledged in University communication outputs; work proactively to identify, plan and coordinate press work for media-relevant activities in the department, in liaison with the University’s Public Affairs Directorate. As required, lead communications with the department’s strategic local, national and international collaborators, partners and projects e.g. Leading on and writing press releases for the highest profile outputs as requested by Head of Department. Operational Communications • • Support and advise senior academics and professional services leaders on the delivery of internal communications. Manage communications to department wide mailing lists in line with agreed strategies. Engaging with Business Managers to ensure Unit mailing lists that feed into departmental ones are kept up to date to ensure communications reach everyone intended. 2 • • • • • • • Responsibility for all departmental communications channels – website(s), social media, newsletters, image banks, etc. – and lead on their development and usage policies. Provide feedback to Divisional and University working groups on systems, external suppliers and partners e.g. as part of the Digital Transformation project. Advise on and be a central contact point in the department for matters relating to; embargos, filming agreements Establish and chair user groups/discussion groups as appropriate to facilitate effective communication. Manage the budget for communications activity in the department, with oversight from the Chief of Staff. Provide leadership to communications personnel across the department, providing guidance and training on departmental branding and strategy. To be aware of, advise and help the wider department in hiring of any further communication roles. Induct all new departmental communication staff ensuring they have a clear understanding of all departmental and university-wide communication policy and processes. Monitor for compliance. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Selection criteria Essential • • • • • • • • • • • • Honours degree in a relevant subject or equivalent experience in a science communication role. Demonstrated continued professional development in communications, marketing or public relations throughout career Significant, relevant and first-hand experience in a higher education communications role; including public relations, media management and outreach Significant and demonstrated ability to conceive, implement and evaluate both creative and successful communication strategies in a large and complex organisation with multiple stakeholder groups Experience of initiating, managing and delivering long-term projects effectively. Excellent written skills with the ability to develop high quality, accurate and consistent communications materials, including about scientific matters or outreach both internally and externally Excellent oral communication including presentation skills with significant evidence of training and developing others to present professionally. Experience of working with a broad range of audiences Excellent interpersonal skills, including diplomacy, confidentiality and the ability to inspire the confidence of senior academic and professional colleagues in the Department and Division Significant demonstrable experience in producing effective web content and working with web content management systems Must be a self-directed strategic thinker with the capacity to problem-solve, take initiative, set priorities, and exercise good judgment and deliver clear messages, in an organised and professional manner Demonstrable ability to assimilate complex information quickly and make it accessible to a wider audience through a variety of communications channels Highly self-motivated, capable of working independently as well as initiating collaborations and working as part of a team 3 Desirable • • • • • Undergraduate or higher degree in the medical sciences Further qualification in Science Communication Evidence of previous successful managerial/supervisory experience Evidence of managing budgets Professional qualification in communication, marketing or public relations Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks 4 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents. • http://www.ox.ac.uk/about_the_university/jobs/professionalandmanagement/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that: • • As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates 5 Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 6
178959 - Senior Operations and Programme Manager - JD
Standard Grade 7: Standard Grade 7: £38,674 - £46,913 with a discretionary range to £51,059 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata).
Centre for Human Genetics, Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN On occasion, Mathematical Institute, Andrew Wiles Building, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG
Postdoctoral Researcher in Neuronal Dysfunction in Alzheimer’s Disease, Oxford-GSK Institute of Molecular and Computational Medicine
Job title Senior Postdoctoral Researcher - Computational Division Medical Sciences Department Nuffield Department of Medicine Location Ludwig Institute for Cancer Research, Old Road Campus Research Building, Oxford, OX3 7DQ Grade and salary Research Grade 8: £48,235 - £57,255 with a discretionary range to £64,228 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata). Hours Full time Contract type Fixed-term contract for 36 months Funding is provided by Ludwig Reporting to Dr Marketa Tomkova Vacancy reference 178673 Additional information This role meets the eligibility requirements for a Skilled Worker Certificate of Sponsorship. About us    What we offer https://hr.admin.ox.ac.uk/staff-benefits  An excellent contributory pension scheme  38 days annual leave  A pensionable Oxford University Weighting allowance of £1,500 per annum (pro rata)  A comprehensive range of childcare services  Family leave schemes  Cycle loan scheme  Discounted bus travel and Season Ticket travel loans  Membership to a variety of social and sports clubs  A welcoming and diverse community University of Oxford - www.ox.ac.uk/about/organisation Nuffield Department of Medicine (NDM) - https://www.ndm.ox.ac.uk Unit - https://www.ludwig.ox.ac.uk The role You will take a leading role in a cutting-edge project at the intersection of genomics, computational biology, and haematological cancer. The project will involve developing novel computational methods to analyse large-scale genomic datasets, integrating multi-omics data, and addressing fundamental biological questions with translational potential. This position is part of a collaborative interdisciplinary initiative at the Ludwig Institute for Cancer Research, which aims to elucidate the molecular mechanisms and early biomarkers of progression to secondary acute myelogenous leukaemia (sAML). sAML is a major unmet medical need with limited therapeutic options. The research will focus on discovery of targetable genetic, epigenetic, or epitranscriptomic mechanisms of sAML progression and resistance to existing treatment, which can be then tested in a variety of in vitro and in vivo models by other members of the team. You will be based in a computational group of Marketa Tomkova, and will interface with leading experimental, clinical, and computational scientists from the groups of Skirmantas Kriaucionis, Stefan Constantinescu, Bethan Psaila, Adam Mead, Yang Shi, Benjamin Schuster-Böckler, and Xin Lu. The project will involve deep characterisation of the mutation, genetic, epigenetic (including DNA methylation and histone changes), chromatin accessibility, bulk and single-cell gene expression, and epi-transcriptomic landscape of serial samples from patients taken before and after progression. This role will be particularly appealing to computational biologists who thrive in an interdisciplinary and collaborative environment that integrates expertise in computing, machine-learning, molecular biology, and clinical science. Responsibilities You will:              Design and lead original research project in computational genomics. Develop novel methodologies and apply methods to analyse large genomic and multi-omics datasets. Identify data-supported hypotheses of molecular mechanisms. Develop research questions within a specific context, conduct individual research. Agree clear task objectives, organise and delegate work to other members of the team. Raise research funds through grant applications and manage own aread of a larger research budget. Collaborate with experimental biologists to validate the hypotheses. Contribute to the overall planning of additional sequencing and other aspects of the study. Regularly write research articles, present papers at national conferences and share responsibility for shaping the research group’s plans. Contribute to the production of scientific reports and publications for high profile journals, including taking leadership in more specialised publications on novel aspects of bioinformatics. Advise and supervise computational staff and students and contribute to the academic environment of the lab. Provide input into outline and full grant proposals. Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year. Undertake mandatory training as required by the University, Division and Department. The specific list of training courses may change from time-to-time, in response to both legal and internal University requirements. Job descriptions can never be comprehensive and you may be required to undertake other similar tasks and responsibilities. 1 Selection criteria Essential         Hold a PhD/DPhil in computational biology, genomics, bioinformatics, computer science, statistics, or a related field. Strong programming skills in Python, R, or similar languages, and proficiency in highperformance computing. Expertise in large-scale genomic data analysis (e.g., sequencing, transcriptomics, epigenomics, single-cell genomics). Proven ability to deliver high quality novel research in relevant fields, for example through journal publications, patents and other IP or authoring widely-used software. A pro-active mindset and the ability to work independently, solve technical challenges, analyse complex datasets, and generate new research ideas. Excellent communication skills and the ability to collaborate effectively within a multidisciplinary team. Experience in generating and documenting reproducible analyses and workflows. Demonstrable ability to organise and prioritise work efficiently whilst delivering results to the required standard and to an agreed schedule. Desirable     Knowledge of epigenetic modifications and mechanisms. Experience in single-cell data analysis. Experience in machine learning techniques. Experience in supervising staff and/or students. Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks 2 How to apply Applications are made through our e-recruitment system and you will find all the information you need about how to apply on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. If you would like to apply, click on the Apply Now button on the ‘Job Details’ page and follow the onscreen instructions to register as a new user or log-in if you have applied previously. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants). Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. Please upload all documents as PDF files with your name and the document type in the filename. Please note using a long file name may prevent you from uploading your documents.  http://www.ox.ac.uk/about_the_university/jobs/research/ All applications must be received by midday UK time on the closing date stated in the online advertisement. If you currently work for the University please note that:   As part of the referencing process, we will contact your current department to confirm basic employment details including reason for leaving. Although employees may hold multiple part-time posts, they may not hold more than the equivalent of a full time post. If you are offered this post, and accepting it would take you over the equivalent of full-time hours, you will be expected to resign from, or reduce hours in, your other posts(s) before starting work in the new post. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly recruitment@ndm.ox.ac.uk To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates 3 Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82, which with effect from 1 October 2023 will be 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. 4
Standard Grade 9: Standard Grade 9: £55,636 - £64,228 with a discretionary range to £70,029 per annum