John Radcliffe Anaesthetic Modular Building
West Wing, Level 6, John Radcliffe Hospital, Oxford, OX3 9DU Web: www.ndcn.ox.ac.uk | Tel: +44(0)1865 234702 | Email: recruitment@ndcn.ox.ac.uk Job title Postdoctoral Researcher Division Medical Sciences Division Department Nuffield Department of Clinical Neurosciences (NDCN) Location John Radcliffe Hospital, Headington, Oxford, OX3 9DU Grade and salary Grade 7: £36,024 – £44,263 per annum Hours Full time Contract type Fixed-term 3 years Reporting to Aarti Jagannath, Associate Professor Vacancy reference 172370 Additional information Research topic Chromatin Architecture, Circadian Rhythms Principal Investigator / supervisor Aarti Jagannath Project team Andre Furger (Biochemistry) + 1 PDRA Project web site https://www.ndcn.ox.ac.uk/team/aarti-jagannath Funding partner The funds supporting this research project are provided by BBSRC (award reference BB/Y005848/1) Recent publications The role We are seeking to appoint an ambitious and creative Postdoctoral Research Associate to join the lab of Professor Aarti Jagannath to work on a collaborative and interdisciplinary project with Prof. Andre Furger and our industrial partner Oxford Biodynamics. Successful applicants will join an exciting research project that aims to understand how cool temperatures, such as experienced during torpor, affect the cellular circadian clock. The circadian clock is a fundamental cellular timekeeper that impacts on most aspects of the physiology of cells and organisms. This BBSRC-funded project builds on recent findings from our labs that identified a novel link between extreme cooling and the circadian clock. We aim to exploit these insights to unravel the molecular mechanisms that underpin the rhythmic expression of circadian core clock genes. Responsibilities = • Plan design and execute experiments that unravel the molecular mechanisms that allow temperature to regulate clock genes in a range of mouse tissues. • Use the EpiSwitch technology developed by Oxford Biodynamics to capture 3D chromatin configuration changes associated with the control of rhythmic gene expression. • Employ 3D structured illumination microscopy (3D-Sim) and fluorescent in situ hybridisation (FISH) approaches to characterise the spatiotemporal organisation of rhythmic gene expression. • Use ChIP-seq and RNA-seq, NET-seq strategies to understand how clock controlled gene expression is orchestrated and affected by cooling, as experienced during torpor. • Assist in the supervision and training of DPhil and MSc students. • Analyse data, prepare presentations and research articles for publication. • Contribute to the generation of new ideas and funding. • Undertake other duties in the department from time to time as determined commensurate with the grade and responsibilities of this post, and any other reasonable request Selection criteria Essential selection criteria • Knowledge and experience of circadian biology. • Previous work with mouse models. • Holds a DPhil or equivalent. • Capacity to plan and execute research programs. • Ability to present and write research articles. • Work within a team to deliver in a timely fashion. Desirable selection criteria • Experience with omics data analysis. • Experience with microscopy/live cell imaging. Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. If you have previously worked for the University we will also verify key information such as your dates of employment and reason for leaving your previous role with the department/unit where you worked. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: = • Work with allergens, Eg laboratory animals, pollen, dust, fish or insects etc. • Work with any substance which has any of the following pictograms on their MSDS: About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognized centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information visit: www.medsci.ox.ac.uk The Nuffield Department of Clinical Neurosciences The Nuffield Department of Clinical Neurosciences (NDCN), led by Prof Kevin Talbot, has over 400 staff and 150 postgraduate students. NDCN has an established research and teaching portfolio with a national and international reputation for excellence. NDCN is based in high quality research and clinical facilities in the West Wing of the John Radcliffe Hospital, alongside the Department's world-class Wellcome Centre for Integrative Neuroimaging (WIN) and the Weatherall Institute of Molecular Medicine (which houses 3 of our research groups), and provides the ideal facilities to translate research from bench to bedside. In keeping with the award of NIHR Comprehensive Biomedical Research Centre status, to a partnership between Oxford University and the Oxford Radcliffe Hospitals NHS Trust, we have developed a highly integrated and interdisciplinary environment in which research, teaching, clinical training and clinical care interact. This enables us to establish new approaches to the understanding, diagnosis and treatment of brain diseases. To this end the Department fosters collaborations worldwide and warmly welcomes visiting scientists, clinical fellows and students. The Department comprises six sections: For more information visit: www.ndcn.ox.ac.uk = Medical Research Council Brain Network Dynamics Unit The MRC BNDU is directed by Professor Peter Magill and is exceptionally multidisciplinary, integrating research programmes that span clinical, experimental and computational neuroscience. The Unit’s collective goal is to understand and exploit the moment-to-moment interactions between nerve cells that are critical for brain functions, with a special focus on the brain circuits underlying movement and memory. For more information visit: www.mrcbndu.ox.ac.uk Nuffield Division of Anaesthesia NDA is led by Associate Professor Andrew Farmery. The NDA is committed to the development and maintenance of internationally competitive research programmes in pain and consciousness; respiration and hypoxia; adult and neuro-intensive care; simulation and human factors training. For more information visit www.nda.ox.ac.uk Division of Clinical Neurology DCN is led by Professor David Bennett. DCN is committed to the development of research programs that improve understanding of the nervous system in health and disease. For more information visit www.dcn.ox.ac.uk The Wellcome Centre for Integrative Neuroimaging (WIN) WIN is a multi-disciplinary neuroimaging research facility led by Heidi Johansen-Berg. WIN aims to bridge the gap between laboratory neuroscience and human health, by performing multi-scale studies spanning from animal models through to human populations. It focuses on the use of Magnetic Resonance Imaging (MRI) for neuroscience research, along with related technologies such as Transcranial Magnetic Stimulation, transcranial Direct Current Stimulation, MEG and EEG. WIN has core locations at the John Radcliffe Hospital (FMRIB), Warneford Hospital (OHBA) and University Science area (BSB). For more information visit www.win.ox.ac.uk Nuffield Laboratory of Ophthalmology NLO is led by Professor Russell Foster, who leads the Sleep & Circadian Neuroscience Institute. NLO pursues scientific and clinical research into a range of areas related to vision, the eye and circadian neuroscience. For more information visit www.nlo.ox.ac.uk Centre for the Prevention of Stroke & Dementia CPSD is led by Professor Peter Rothwell. The centre carries out research that increases understanding of the causes of cerebrovascular disease. Its aims are to improve prevention of stroke and dementia by earlier diagnosis, more reliable prognostication, and more effective use of existing preventive treatments in routine clinical practice. For more information visit www.cpsd.ox.ac.uk Working at NDCN NDCN actively promotes a healthy work life balance amongst employees through a number of family friendly policies. See https://hr.admin.ox.ac.uk/staff-benefits for further information. The University of Oxford is a member of the Athena SWAN Charter and holds an institutional Bronze Athena SWAN award. The Department of Clinical Neurosciences holds a departmental Silver Athena award in recognition of its efforts to introduce organisational and cultural practices that promote advancement of gender equality: representation, progression and success for all. = How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly: recruitment@ndcn.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. = The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82 of 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. = Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependants. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency backup care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care The University has excellent childcare services, including five University nurseries as well as Universitysupported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. Oxford Research Staff Society (OxRSS) A society run by and for Oxford University research staff. It offers researchers a range of social and professional networking opportunities. Membership is free, and all researchers employed by Oxford University are welcome to join. Subscribe at researchstaff-subscribe@maillist.ox.ac.uk to join the mailing list to find out about upcoming events and other information for researchers, or contact the committee on committee@oxrss.ox.ac.uk. For more information, see www.ox.ac.uk/oxrss, Twitter @ResStaffOxford, and Facebook www.facebook.com/oxrss. =
Is Part Of
Standard Grade 4: £25,138 – £28,759 per annum
We are seeking to appoint an ambitious and creative Postdoctoral Researcher to join the lab of Professor Aarti Jagannath to work on a collaborative and interdisciplinary project with Prof. Andre Furger and our industrial partner Oxford Biodynamics. Successful applicants will join an exciting research project that aims to understand how cool temperatures, such as experienced during torpor, affect the cellular circadian clock. The circadian clock is a fundamental cellular timekeeper that impacts on most aspects of the physiology of cells and organisms. This BBSRC-funded project builds on recent findings from our labs that identified a novel link between extreme cooling and the circadian clock. We aim to exploit these insights to unravel the molecular mechanisms that underpin the rhythmic expression of circadian core clock genes. Essential selection criteria: Knowledge and experience of circadian biology. Previous work with mouse models. Holds a DPhil or equivalent. Capacity to plan and execute research programs. Ability to present and write research articles. Work within a team to deliver in a timely fashion. Desirable selection criteria: Experience with omics data analysis. Experience with microscopy/live cell imaging. Please see the below 'Job Description' for further details on the project, responsibilities, and selection criteria, as well as further information about the university and how to apply. This post is full-time and fixed for 3 years . Only applications received before 12:00 midday on 29th of May 2024 will be considered. Interviews are expected to be held as soon as possible thereafter.
We are seeking an ambitious and highly motivated biotechnologist or bioengineer or biochemist with relevant experience to work in a programme of research that aims to validate and refine biomarkers based on measurements in neuronally-derived extracellular vesicles for Parkinson’s disease prediction and stratification. This is an exciting opportunity funded by the MRC that builds on previous research by the group in this area to develop the biomarker further for clinical application. The successful candidate will validate and extend the biomarker indication in samples obtained from deeply phenotyped longitudinal cohorts and interact with industry partners and chemists to optimise microfluidic devices for optimal biomarker isolation and quantification. Some of your duties will include managing your own academic research and take initiatives to improve existing assays, and using established lab protocols to isolate neuronally-derived extracellular vesicles from biofluids using immunocapture and analyse scientific data. It is essential that you hold a PhD with significant relevant laboratory experience, have publications in Biomarker studies or relevant biotechnology methodologies and use of ELISA or similar assays. It is desirable that you have previous experience in the study of Neurodegeneration and experience with the use or design of microfluidic chips. Please see the below 'Job Description' for further details on the responsibilities and selection criteria, as well as further information about the university and how to apply. The post is full time for a fixed term for 2 years in the first instance. Only application received before 12.00 midday on Tuesday 7th May will be considered. Interviews will held as soon as possible thereafter.
Postdoctoral Researcher in Advanced Image Analysis for Brain Imaging
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West Wing, Level 6, John Radcliffe Hospital, Oxford, OX3 9DU Web: www.ndcn.ox.ac.uk | Tel: +44(0)1865 234702 | Email: recruitment@ndcn.ox.ac.uk Job title Biotechnologist – Biomarkers in Neurodegeneration Division Medical Sciences Division Department Nuffield Department of Clinical Neurosciences (NDCN) Location John Radcliffe Hospital, Headington, Oxford, OX3 9DU Grade 8: £45,585 – £59,421 per annum Grade and salary A less experienced candidate may be appointed at Grade 7 with a commensurate adjustment in essential criteria, responsibilities and duties. Hours Full time Contract type Fixed-term, 2 years in the first instance Reporting to Professor George Tofaris Vacancy reference 172203 Research topic Extracellular vesicle biomarkers in Parkinson’s disease prediction and stratification Principal Investigator / supervisor Professor George Tofaris Project team https://www.ndcn.ox.ac.uk/research/molecularneurodegeneration-research-group Project web site www.ox.ac.uk/ https://www.ndcn.ox.ac.uk/team/george-tofaris Funding partner The funds supporting this research project are provided by MRC Developmental Pathway Funding Scheme Recent publications Yan et al., JAMA Neurol 2024; 81(1):59-68; Jiang et al., J Neurol Neurosurg. Psychiatry 2020, 91(7): 720-729; Jiang et al., Mov. Disorders 2021, 36(11): 2663-2669; Tanudjojo et al., Nature Commun. 2021, 12(1):3817; Zenko et al., Science Adv. 9(24):eadd8910. The role We are seeking an ambitious and highly motivated biotechnologist or bioengineer or biochemist with relevant experience to work in a programme of research that aims to validate and refine biomarkers based on measurements in neuronally-derived extracellular vesicles for Parkinson’s disease prediction and stratification. This is an exciting opportunity funded by the MRC that builds on previous research by the group in this area to develop the biomarker further for clinical application. The successful candidate will validate and extend the biomarker indication in samples obtained from deeply phenotyped longitudinal cohorts and interact with industry partners and chemists to optimise microfluidic devices for optimal biomarker isolation and quantification. As such, the post will offer an excellent opportunity for studies in Parkinson’s disease diagnostics using state-of-the-art facilities available at the Kavli Institute for Nanoscience Discovery and the Nuffield Department of Clinical Neurosciences at the University of Oxford. The post-holder will also benefit from and be exposed to interactions with clinicians and work alongside a multidisciplinary team of basic researchers in the Molecular Neurodegeneration Research Group. For details check the lab website at: https://www.ndcn.ox.ac.uk/research/molecular- neurodegeneration-research-group You will have an aptitude for biomarker studies or development of related microfluidic chips, with a proven track record of research in this area as evidenced by peer-reviewed publications, and the enthusiasm to lead a project as well as the ability to work collaboratively within a team. Responsibilities • • • • • • Manage own academic research and take initiatives to improve existing assays. Use established lab protocols to isolate neuronally-derived extracellular vesicles from biofluids using immunocapture and analyse scientific data Perform experiments involving microfluidic chips, MSD platforms or similar assays Act as a source of information and advice to graduate students on scientific protocols and experimental techniques Present research and write up results for publication. Undertake other duties in the department from time to time as determined commensurate with the grade and responsibilities of this post, and any other reasonable request Selection criteria Essential selection criteria • • • • • • • = Drive and enthusiasm to both lead a project and work as a member of a team Excellent written and oral communication skills Hold a PhD with at least 2 years of relevant laboratory experience Publications in Biomarker studies or relevant biotechnology methodologies Use of ELISA or similar assays Experience in handling patient biosamples Previous use of “-omics” in biomarker discovery • Working knowledge of statistical programs relevant to basic research Desirable selection criteria • Previous experience in the study of Neurodegeneration • Experience with the use or design of microfluidic chips Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. If you have previously worked for the University we will also verify key information such as your dates of employment and reason for leaving your previous role with the department/unit where you worked. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • Lone Working • Working with blood, human products and human tissues • Work with any substance which has any of the following pictograms on their MSDS: About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. = While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognized centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information visit: www.medsci.ox.ac.uk The Nuffield Department of Clinical Neurosciences The Nuffield Department of Clinical Neurosciences (NDCN), led by Prof Kevin Talbot, has over 400 staff and 150 postgraduate students. NDCN has an established research and teaching portfolio with a national and international reputation for excellence. NDCN is based in high quality research and clinical facilities in the West Wing of the John Radcliffe Hospital, alongside the Department's world-class Wellcome Centre for Integrative Neuroimaging (WIN) and the Weatherall Institute of Molecular Medicine (which houses 3 of our research groups), and provides the ideal facilities to translate research from bench to bedside. In keeping with the award of NIHR Comprehensive Biomedical Research Centre status, to a partnership between Oxford University and the Oxford Radcliffe Hospitals NHS Trust, we have developed a highly integrated and interdisciplinary environment in which research, teaching, clinical training and clinical care interact. This enables us to establish new approaches to the understanding, diagnosis and treatment of brain diseases. To this end the Department fosters collaborations worldwide and warmly welcomes visiting scientists, clinical fellows and students. The Department comprises six sections: For more information visit: www.ndcn.ox.ac.uk Medical Research Council Brain Network Dynamics Unit The MRC BNDU is directed by Professor Peter Magill and is exceptionally multidisciplinary, integrating research programmes that span clinical, experimental and computational neuroscience. The Unit’s collective goal is to understand and exploit the moment-to-moment interactions between nerve cells that are critical for brain functions, with a special focus on the brain circuits underlying movement and memory. For more information visit: www.mrcbndu.ox.ac.uk Nuffield Division of Anaesthesia NDA is led by Associate Professor Andrew Farmery. The NDA is committed to the development and maintenance of internationally competitive research programmes in pain and consciousness; respiration and hypoxia; adult and neuro-intensive care; simulation and human factors training. For more information visit www.nda.ox.ac.uk Division of Clinical Neurology DCN is led by Professor David Bennett. DCN is committed to the development of research programs that improve understanding of the nervous system in health and disease. = For more information visit www.dcn.ox.ac.uk The Wellcome Centre for Integrative Neuroimaging (WIN) WIN is a multi-disciplinary neuroimaging research facility led by Heidi Johansen-Berg. WIN aims to bridge the gap between laboratory neuroscience and human health, by performing multi-scale studies spanning from animal models through to human populations. It focuses on the use of Magnetic Resonance Imaging (MRI) for neuroscience research, along with related technologies such as Transcranial Magnetic Stimulation, transcranial Direct Current Stimulation, MEG and EEG. WIN has core locations at the John Radcliffe Hospital (FMRIB), Warneford Hospital (OHBA) and University Science area (BSB). For more information visit www.win.ox.ac.uk Nuffield Laboratory of Ophthalmology NLO is led by Professor Russell Foster, who leads the Sleep & Circadian Neuroscience Institute. NLO pursues scientific and clinical research into a range of areas related to vision, the eye and circadian neuroscience. For more information visit www.nlo.ox.ac.uk Centre for the Prevention of Stroke & Dementia CPSD is led by Professor Peter Rothwell. The centre carries out research that increases understanding of the causes of cerebrovascular disease. Its aims are to improve prevention of stroke and dementia by earlier diagnosis, more reliable prognostication, and more effective use of existing preventive treatments in routine clinical practice. For more information visit www.cpsd.ox.ac.uk Working at NDCN NDCN actively promotes a healthy work life balance amongst employees through a number of family friendly policies. See https://hr.admin.ox.ac.uk/staff-benefits for further information. The University of Oxford is a member of the Athena SWAN Charter and holds an institutional Bronze Athena SWAN award. The Department of Clinical Neurosciences holds a departmental Silver Athena award in recognition of its efforts to introduce organisational and cultural practices that promote advancement of gender equality: representation, progression and success for all. = How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of three referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly: recruitment@ndcn.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. = Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82 of 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. = Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependants. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency backup care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care The University has excellent childcare services, including five University nurseries as well as Universitysupported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. Oxford Research Staff Society (OxRSS) A society run by and for Oxford University research staff. It offers researchers a range of social and professional networking opportunities. Membership is free, and all researchers employed by Oxford University are welcome to join. Subscribe at researchstaff-subscribe@maillist.ox.ac.uk to join the mailing list to find out about upcoming events and other information for researchers, or contact the committee on committee@oxrss.ox.ac.uk. For more information, see www.ox.ac.uk/oxrss, Twitter @ResStaffOxford, and Facebook www.facebook.com/oxrss. =
Postdoctoral Research Associate in Sleep Medicine
Nuffield Department of Clinical Neurosciences (NDCN), John Radcliffe Hospital, Headington, Oxford, OX3 9DU
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Grade 8: £45,585 – £59,421 per annum A less experienced candidate may be appointed at Grade 7 with a commensurate adjustment in essential criteria, responsibilities and duties.
We are seeking a motivated post-doctoral research associate to join the Experimental and Clinical Sleep Medicine group within the Nuffield Department of Clinical Neurosciences. We conduct human experimental and clinical studies on sleep and disorders of sleep with the aim of understanding their pathophysiology and treatment. The post holder will work on a new programme grant funded by the National Institute for Health and Care Research (NIHR) aimed at developing and testing a novel behavioural intervention for shift- work sleep disorder in NHS workers. The post-holder will be part of a multi- disciplinary team comprising experts in sleep and circadian science, occupational medicine, health psychology, primary care, health economics, and clinical trial methodology. Principal duties include reviewing existing literature, developing novel intervention materials, training team members on intervention delivery, and co-ordinating a feasibility study to assess intervention acceptability. Some of your duties will include developing the content for a novel intervention for shift-work sleep disorder and reviewing published literature and work closely with our patient and public involvement advisory group to develop and refine intervention materials. It is essential that you hold a PhD in neuroscience, psychology or related discipline, or have submitted a PhD thesis prior to taking up this appointment and have expertise in the assessment of sleep disorders or circadian rhythm sleep-wake disorders. It is desirable that you have previous experience of obtaining and maintaining regulatory and ethics approvals and have expertise in shift-work and/or shift- work sleep disorder. Please see the below 'Job Description' for further details on the responsibilities and selection criteria, as well as further information about the university and how to apply. **The post is full time for a fixed term until 31st December 2025 in the first instance, but with the possibility of extension until 31st March 2028 following funder review. ** **Only applications received before 12.00 midday on Wednesday 1st May will be considered.** **Interviews will be held as soon as possible thereafter.**
Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Headington, Oxford, OX3 9DU
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Nuffield Department of Clinical Neurosciences
We are looking for an Admin Assistant to be a part of the Oxford Parkinson’s Disease Centre Clinical Team. The role will involve working with a number of key stakeholders at different levels to ensure the smooth running of the OPDC cohort. Following training and ongoing support, the post holder will need to manage their own workload effectively and autonomously. Working closely with the Clinical Project Manager and Clinical Lead. The role will be largely based at the John Radcliffe Hospital, Oxford however will remotely cover other sites involved in OPDC including Cambridge and Sheffield. This post will involve working alongside the current OPDC research administrator to provide sufficient administrative and patient-facing support for the clinical cohort of the Oxford Parkinson’s Disease Centre. Key cohort aims are to improve understanding of the biology of early Parkinson’s and identify predictors of Parkinson’s onset and subsequent progression. The Discovery cohort is seen as a beacon of excellence within Oxford Neuroscience, and is strongly committed to improving public engagement with research and promoting outreach activities. It exemplifies multi-disciplinary translational neuroscience in Oxford at its best, representing a close and interactive collaboration between research laboratories in the basic sciences with clinicians from the Nuffield Division of Clinical Neurology. The post is funded for 12 months, with potential to extend beyond this following successful review and the applicant’s choice. Essential selection criteria: Experience of managing administrative processes and reception or customer facing work. The ability to work independently once fully trained, with a willingness to resolve situations, as well as knowing when to refer issues to others. The ability to organise own workload and to work to deadlines, evidenced by formal qualifications at (for example BTEC ND, NVQ Level 3 or equivalent) and/or significant work experience at a similar level. Ability to help organise events and make administrative arrangements. Ability to use standard computer programs (Outlook, Word, Excel). Previous experience of working as part of a team in an office environment, with a flexible and enthusiastic approach to working and using own initiative. Desirable selection criteria: Experience of working within an HE institution or within a service industry environment. Knowledge of current national systems and strictures for research in the NHS. Administration experience in a clinical research environment. Please see the below 'Job Description' for further details on the project, responsibilities, and selection criteria, as well as further information about the university and how to apply. This post is full-time and fixed until 31st March 2025. Only applications received before 12:00 midday on Tuesday 7th May 2024 will be considered. Interviews are expected to be held as soon as possible thereafter.
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We are seeking to appoint an ambitious and creative **Postdoctoral Researcher** to join the lab of Professor Aarti Jagannath to work on a collaborative and interdisciplinary project with Prof. Andre Furger and our industrial partner Oxford Biodynamics. Successful applicants will join an exciting research project that aims to understand how cool temperatures, such as experienced during torpor, affect the cellular circadian clock. The circadian clock is a fundamental cellular timekeeper that impacts on most aspects of the physiology of cells and organisms. This BBSRC-funded project builds on recent findings from our labs that identified a novel link between extreme cooling and the circadian clock. We aim to exploit these insights to unravel the molecular mechanisms that underpin the rhythmic expression of circadian core clock genes. Essential selection criteria: * Knowledge and experience of circadian biology. * Previous work with mouse models. * Holds a DPhil or equivalent. * Capacity to plan and execute research programs. * Ability to present and write research articles. * Work within a team to deliver in a timely fashion. Desirable selection criteria: * Experience with omics data analysis. * Experience with microscopy/live cell imaging. **Please see the below 'Job Description' for further details on the project, responsibilities, and selection criteria, as well as further information about the university and how to apply.** **This post is full-time and fixed for 3 years .** **Only applications received before 12:00 midday on 29th of May 2024 will be considered.** **Interviews are expected to be held as soon as possible thereafter.**
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Standard Grade 7: £36,024 – £44,263 per annum
John Radcliffe West Wing and Children's Hospital
Clinical Neurosciences, Nuffield Department of
We are looking for an **Admin Assistant** to be a part of the Oxford Parkinson’s Disease Centre Clinical Team. The role will involve working with a number of key stakeholders at different levels to ensure the smooth running of the OPDC cohort. Following training and ongoing support, the post holder will need to manage their own workload effectively and autonomously. Working closely with the Clinical Project Manager and Clinical Lead. The role will be largely based at the John Radcliffe Hospital, Oxford however will remotely cover other sites involved in OPDC including Cambridge and Sheffield. This post will involve working alongside the current OPDC research administrator to provide sufficient administrative and patient-facing support for the clinical cohort of the Oxford Parkinson’s Disease Centre. Key cohort aims are to improve understanding of the biology of early Parkinson’s and identify predictors of Parkinson’s onset and subsequent progression. The Discovery cohort is seen as a beacon of excellence within Oxford Neuroscience, and is strongly committed to improving public engagement with research and promoting outreach activities. It exemplifies multi- disciplinary translational neuroscience in Oxford at its best, representing a close and interactive collaboration between research laboratories in the basic sciences with clinicians from the Nuffield Division of Clinical Neurology. The post is funded for 12 months, with potential to extend beyond this following successful review and the applicant’s choice. **Essential selection criteria:** * Experience of managing administrative processes and reception or customer facing work. * The ability to work independently once fully trained, with a willingness to resolve situations, as well as knowing when to refer issues to others. * The ability to organise own workload and to work to deadlines, evidenced by formal qualifications at (for example BTEC ND, NVQ Level 3 or equivalent) and/or significant work experience at a similar level. * Ability to help organise events and make administrative arrangements. * Ability to use standard computer programs (Outlook, Word, Excel). * Previous experience of working as part of a team in an office environment, with a flexible and enthusiastic approach to working and using own initiative. **Desirable selection criteria:** * Experience of working within an HE institution or within a service industry environment. * Knowledge of current national systems and strictures for research in the NHS. * Administration experience in a clinical research environment. Please see the below 'Job Description' for further details on the project, responsibilities, and selection criteria, as well as further information about the university and how to apply. **This post is full-time and fixed until 31st March 2025.** **Only applications received before 12:00 midday on Tuesday 7th May 2024 will be considered.** **Interviews are expected to be held as soon as possible thereafter.**
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Nuffield Department of Clinical Neurosciences (NDCN) ,Sleep and Circadian Neuroscience Institute, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford, OX1 3QU
We are looking for a **Postdoctoral Researcher in Advanced Image Analysis for Brain Imaging** to join the Nuffield Department of Clinical Neurosciences (NDCN). This role will be to develop and apply image processing algorithms and software, to process two-timepoint (longitudinal) data from UK Biobank brain imaging. This will involve development of image alignment methods, population template image generation, and brain pathology modelling. All of this will be specific to longitudinal imaging, i.e., where we have more than one timepoint imaging from each participant. You will be joining the FMRIB Analysis Group in Oxford, which is a leading research group in brain image analysis, and produces FSL (FMRIB Software Library), the world’s most widely used research software that spans all the major structural and functional brain imaging modalities. FMRIB members Smith and Miller are the scientific leads of the brain imaging component of UK Biobank. Successful applicants will also have the opportunity to contribute to the next generation of FSL tools, which is the most widely used software toolbox that combines structural, functional, and diffusion MRI analysis. FSL is used in more than 1000 universities and hospitals worldwide (160,000 downloads in the past 5 years). We are looking for a postdoc with experience in image analysis novel methods development and software. Applicants will be expected to hold a PhD/DPhil in relevant quantitative area, as well as knowledge of statistics and/or Bayesian learning, and necessary mathematical and computational skills to put these into practice. Skills in computer programming (e.g. Matlab, Python, or C++), a track record in research, and in depth knowledge of image processing and statistics are essential. Please see the below 'Job Description' for further details on the role, responsibilities, and selection criteria, as well as further information about the university and how to apply. **This post is full time and fixed term for 3 years in the first instance.** **Only applications received before midday 12:00 on Tuesday 30th April 2024 will be considered. ** **Interviews will be held as soon as possible thereafter.**
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We are looking for a Postdoctoral Researcher in Advanced Image Analysis for Brain Imaging to join the Nuffield Department of Clinical Neurosciences (NDCN). This role will be to develop and apply image processing algorithms and software, to process two-timepoint (longitudinal) data from UK Biobank brain imaging. This will involve development of image alignment methods, population template image generation, and brain pathology modelling. All of this will be specific to longitudinal imaging, i.e., where we have more than one timepoint imaging from each participant. You will be joining the FMRIB Analysis Group in Oxford, which is a leading research group in brain image analysis, and produces FSL (FMRIB Software Library), the world’s most widely used research software that spans all the major structural and functional brain imaging modalities. FMRIB members Smith and Miller are the scientific leads of the brain imaging component of UK Biobank. Successful applicants will also have the opportunity to contribute to the next generation of FSL tools, which is the most widely used software toolbox that combines structural, functional, and diffusion MRI analysis. FSL is used in more than 1000 universities and hospitals worldwide (160,000 downloads in the past 5 years). We are looking for a postdoc with experience in image analysis novel methods development and software. Applicants will be expected to hold a PhD/DPhil in relevant quantitative area, as well as knowledge of statistics and/or Bayesian learning, and necessary mathematical and computational skills to put these into practice. Skills in computer programming (e.g. Matlab, Python, or C++), a track record in research, and in depth knowledge of image processing and statistics are essential. Please see the below 'Job Description' for further details on the role, responsibilities, and selection criteria, as well as further information about the university and how to apply. This post is full time and fixed term for 3 years in the first instance. Only applications received before midday 12:00 on Tuesday 30th April 2024 will be considered. Interviews will be held as soon as possible thereafter.
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We are seeking a motivated post-doctoral research associate to join the Experimental and Clinical Sleep Medicine group within the Nuffield Department of Clinical Neurosciences. We conduct human experimental and clinical studies on sleep and disorders of sleep with the aim of understanding their pathophysiology and treatment. The post holder will work on a new programme grant funded by the National Institute for Health and Care Research (NIHR) aimed at developing and testing a novel behavioural intervention for shift-work sleep disorder in NHS workers. The post-holder will be part of a multi-disciplinary team comprising experts in sleep and circadian science, occupational medicine, health psychology, primary care, health economics, and clinical trial methodology. Principal duties include reviewing existing literature, developing novel intervention materials, training team members on intervention delivery, and co-ordinating a feasibility study to assess intervention acceptability. Some of your duties will include developing the content for a novel intervention for shift-work sleep disorder and reviewing published literature and work closely with our patient and public involvement advisory group to develop and refine intervention materials. It is essential that you hold a PhD in neuroscience, psychology or related discipline, or have submitted a PhD thesis prior to taking up this appointment and have expertise in the assessment of sleep disorders or circadian rhythm sleep-wake disorders. It is desirable that you have previous experience of obtaining and maintaining regulatory and ethics approvals and have expertise in shift-work and/or shift-work sleep disorder. Please see the below 'Job Description' for further details on the responsibilities and selection criteria, as well as further information about the university and how to apply. The post is full time for a fixed term until 31st December 2025 in the first instance, but with the possibility of extension until 31st March 2028 following funder review. Only applications received before 12.00 midday on Wednesday 1st May will be considered. Interviews will be held as soon as possible thereafter.
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We are seeking an ambitious and highly motivated biotechnologist or bioengineer or biochemist with relevant experience to work in a programme of research that aims to validate and refine biomarkers based on measurements in neuronally-derived extracellular vesicles for Parkinson’s disease prediction and stratification. This is an exciting opportunity funded by the MRC that builds on previous research by the group in this area to develop the biomarker further for clinical application. The successful candidate will validate and extend the biomarker indication in samples obtained from deeply phenotyped longitudinal cohorts and interact with industry partners and chemists to optimise microfluidic devices for optimal biomarker isolation and quantification. Some of your duties will include managing your own academic research and take initiatives to improve existing assays, and using established lab protocols to isolate neuronally-derived extracellular vesicles from biofluids using immunocapture and analyse scientific data. It is essential that you hold a PhD with significant relevant laboratory experience, have publications in Biomarker studies or relevant biotechnology methodologies and use of ELISA or similar assays. It is desirable that you have previous experience in the study of Neurodegeneration and experience with the use or design of microfluidic chips. Please see the below 'Job Description' for further details on the responsibilities and selection criteria, as well as further information about the university and how to apply. **The post is full time for a fixed term for 2 years in the first instance.** **Only application received before 12.00 midday on Tuesday 7th May will be considered.** **Interviews will held as soon as possible thereafter. **
West Wing, Level 6, John Radcliffe Hospital, Oxford, OX3 9DU Web: www.ndcn.ox.ac.uk | Tel: +44(0)1865 234702 | Email: recruitment@ndcn.ox.ac.uk Job title Postdoctoral Researcher in Advanced Image Analysis for Brain Imaging Division Medical Sciences Division Department Nuffield Department of Clinical Neurosciences (NDCN) Location John Radcliffe Hospital, Headington, Oxford, OX3 9DU Grade 8: £45,558 - £54,395 per annum Grade and salary A less experienced candidate may be appointed at Grade 7 (£36,024 - £44,263 p.a.) with a commensurate adjustment in selection criteria, responsibilities, duties and job title Hours Full time Contract type Fixed term for 3 years in the first instance Reporting to Prof Stephen Smith Vacancy reference 171940 Research topic Advanced Brain Image Analysis Principal Investigator / supervisor Stephen Smith, Rick Lange, Jesper Andersson Project team WIN Analysis Group Project web site www.win.ox.ac.uk/research/analysis-research The role This role will be to develop and apply image processing algorithms and software, to process two-timepoint (longitudinal) data from UK Biobank brain imaging. This will involve development of image alignment methods, population template image generation, and brain pathology modelling. All of this will be specific to longitudinal imaging, i.e., where we have more than one timepoint imaging from each participant. Background: The FMRIB Analysis Group in Oxford is a leading research group in brain image analysis, and produced FSL (FMRIB Software Library), the world’s most widely used research software that spans all the major structural and functional brain imaging modalities. FMRIB members Smith and Miller are the scientific leads of the brain imaging component of UK Biobank. FMRIB Oxford developed FBP (FMRIB Biobank Pipeline,) v1 for processing brain imaging data on behalf of UKB. To date, we have processed ~60,000 participants’ timepoint1 datasets for release by UKB. This processing includes: semi-automated QC, image processing and artefact removal, and estimation of over 4,000 IDPs - image-derived phenotypes, distinct measures of brain structure and function, ranging from simple estimates of tissue volume to measures of functional connectivity between different brain regions. All seven brain imaging modalities are processed: T1, T2FLAIR and swMRI structural data, diffusion structural connectivity and tissue microstructure, resting and task functional data, and ASL blood flow. All enhancements to FBP v1 have been “backwards compatible” expansions, in order to maintain consistency with already-released subjects’ IDPs, as new subjects are added. There are many aspects of the pipeline that can be improved on, and we are now starting to design and create FBP v2, revisiting all processing and algorithmic decisions to take advantage of advances in the field. This new version will not be backwards compatible with v1, to allow for unconstrained optimal design. None of the above includes modelling of longitudinal data. The modest number of existing timepoint2 datasets (around 5,000) have been processed as if they were from new participants. Our proposal here is to develop longitudinal modelling as part of pipeline v2, which fits well with the timing of the timepoint2 scanning, and pipeline v2 development. Using both the existing and new pipeline components, we will process all timepoint2 data. We will then utilize these developments to study aging and later-life disease. A major goal of our group is to extend the reach of imaging neuroscience to take full advantage of the richness of the new big data imaging resources, such as: major advances in the quality of data; complementarity of multi-modal imaging; large subject numbers; and linked information about health outcomes, genetics, and risk factors. This requires new research across multiple domains, including: integrated cross-modal analysis, particularized biologicallyinterpretable markers, machine learning, and modelling of variation in populations to the characterisation of individual subjects. Successful applicants will also have the opportunity to contribute to the next generation of FSL tools, which is the most widely used software toolbox that combines structural, functional, and diffusion MRI analysis. FSL is used in more than 1000 universities and hospitals worldwide (160,000 downloads in the past 5 years). We are looking for a postdoc with experience in image analysis novel methods development and software. Applicants will be expected to hold a PhD/DPhil in relevant quantitative area, as well as have knowledge of statistics and/or Bayesian learning, and necessary mathematical and computational skills to put these into practice. Skills in computer programming (e.g. Matlab, Python, or C++) are essential. = Responsibilities • Develop new mathematical approaches in brain image analysis in the research areas outlined above • Develop software implementation of these approaches in FSL • Develop advanced processing algorithm and software, quality check and process data, and generate models on relevant datasets • Communicate the research both internally within the lab, and externally through journal publications and conference presentations • Work effectively with other members of the collaborative project • Undertake other duties in the department from time to time as determined commensurate with the grade and responsibilities of this post, and any other reasonable request Selection criteria Essential selection criteria • PhD/DPhil in relevant quantitative area. • Track record in research commensurate with level of experience • In depth knowledge of image processing • In depth knowledge in statistics, and/or machine learning, and/or engineering maths in the broad sense • Excellent communication skills (oral and written) • Proficiency in computer programming (Matlab, Python, or C/C++) • Ability to work independently and meet deadlines • Excellent analytical skills Desirable selection criteria • Experience with medical image processing (ideally brain MRI) • Good knowledge in statistics and/or Bayesian learning Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. If you have previously worked for the University we will also verify key information such as your dates of employment and reason for leaving your previous role with the department/unit where you worked. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks = About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognized centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information visit: www.medsci.ox.ac.uk The Nuffield Department of Clinical Neurosciences The Nuffield Department of Clinical Neurosciences (NDCN), led by Prof Kevin Talbot, has over 400 staff and 150 postgraduate students. NDCN has an established research and teaching portfolio with a national and international reputation for excellence. NDCN is based in high quality research and clinical facilities in the West Wing of the John Radcliffe Hospital, alongside the Department's world-class Wellcome Centre for Integrative Neuroimaging (WIN) and the Weatherall Institute of Molecular Medicine (which houses 3 of our research groups), and provides the ideal facilities to translate research from bench to bedside. In keeping with the award of NIHR Comprehensive Biomedical Research Centre status, to a partnership between Oxford University and the Oxford Radcliffe Hospitals NHS Trust, we have developed a highly integrated and interdisciplinary environment in which research, teaching, clinical training and clinical care interact. This enables us to establish new approaches to the understanding, diagnosis and treatment of brain diseases. To this end the Department fosters collaborations worldwide and warmly welcomes visiting scientists, clinical fellows and students. The Department comprises six sections: For more information visit: www.ndcn.ox.ac.uk Medical Research Council Brain Network Dynamics Unit The MRC BNDU is directed by Professor Peter Magill and is exceptionally multidisciplinary, integrating research programmes that span clinical, experimental and computational neuroscience. The Unit’s collective goal is to understand and exploit the moment-to-moment = interactions between nerve cells that are critical for brain functions, with a special focus on the brain circuits underlying movement and memory. For more information visit: www.mrcbndu.ox.ac.uk Nuffield Division of Anaesthesia NDA is led by Associate Professor Andrew Farmery. The NDA is committed to the development and maintenance of internationally competitive research programmes in pain and consciousness; respiration and hypoxia; adult and neuro-intensive care; simulation and human factors training. For more information visit www.nda.ox.ac.uk Division of Clinical Neurology DCN is led by Professor David Bennett. DCN is committed to the development of research programs that improve understanding of the nervous system in health and disease. For more information visit www.dcn.ox.ac.uk The Wellcome Centre for Integrative Neuroimaging (WIN) WIN is a multi-disciplinary neuroimaging research facility led by Heidi Johansen-Berg. WIN aims to bridge the gap between laboratory neuroscience and human health, by performing multi-scale studies spanning from animal models through to human populations. It focuses on the use of Magnetic Resonance Imaging (MRI) for neuroscience research, along with related technologies such as Transcranial Magnetic Stimulation, transcranial Direct Current Stimulation, MEG and EEG. WIN has core locations at the John Radcliffe Hospital (FMRIB), Warneford Hospital (OHBA) and University Science area (BSB). For more information visit www.win.ox.ac.uk Nuffield Laboratory of Ophthalmology NLO is led by Professor Russell Foster, who leads the Sleep & Circadian Neuroscience Institute. NLO pursues scientific and clinical research into a range of areas related to vision, the eye and circadian neuroscience. For more information visit www.nlo.ox.ac.uk Centre for the Prevention of Stroke & Dementia CPSD is led by Professor Peter Rothwell. The centre carries out research that increases understanding of the causes of cerebrovascular disease. Its aims are to improve prevention of stroke and dementia by earlier diagnosis, more reliable prognostication, and more effective use of existing preventive treatments in routine clinical practice. For more information visit www.cpsd.ox.ac.uk Working at NDCN NDCN actively promotes a healthy work life balance amongst employees through a number of family friendly policies. See https://hr.admin.ox.ac.uk/staff-benefits for further information. The University of Oxford is a member of the Athena SWAN Charter and holds an institutional Bronze Athena SWAN award. The Department of Clinical Neurosciences holds a departmental Silver Athena award in recognition of its efforts to introduce organisational and cultural practices that promote advancement of gender equality: representation, progression and success for all. = How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly: recruitment@ndcn.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. = Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82 of 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. = Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependants. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency backup care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care The University has excellent childcare services, including five University nurseries as well as Universitysupported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. Oxford Research Staff Society (OxRSS) A society run by and for Oxford University research staff. It offers researchers a range of social and professional networking opportunities. Membership is free, and all researchers employed by Oxford University are welcome to join. Subscribe at researchstaff-subscribe@maillist.ox.ac.uk to join the mailing list to find out about upcoming events and other information for researchers, or contact the committee on committee@oxrss.ox.ac.uk. For more information, see www.ox.ac.uk/oxrss, Twitter @ResStaffOxford, and Facebook www.facebook.com/oxrss. =
Grade 7: £34,303 - £42,155 per annum A less experienced candidate may be appointed at Grade 6 (£32,332 – £38,205 per annum), with a commensurate adjustment in either the essential criteria, responsibilities or duties
has min currency value (1..1)
West Wing, Level 6, John Radcliffe Hospital, Oxford, OX3 9DU Web: www.ndcn.ox.ac.uk | Tel: +44(0)1865 234702 | Email: recruitment@ndcn.ox.ac.uk Job title Postdoctoral Research Associate in Sleep Medicine Division Medical Sciences Division Department Nuffield Department of Clinical Neurosciences (NDCN) Location Sleep and Circadian Neuroscience Institute, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford, OX1 3QU Grade 7: £34,303 - £42,155 per annum Grade and salary A less experienced candidate may be appointed at Grade 6 (£32,332 – £38,205 per annum), with a commensurate adjustment in either the essential criteria, responsibilities or duties Hours Full time Contract type Fixed term until 31st December 2025 in the first instance Possibility of extension until 31st March 2028 following funder review. Reporting to Professor Simon Kyle Vacancy reference 172222 Additional information NIHR Programme Grants for Applied Research (PGfAR) Research topic Sleep and circadian rhythm disruption Principal Investigator / supervisor Professor Simon Kyle Project team Experimental and Clinical Sleep Medicine Project web site www.ox.ac.uk/ Funding partner The funds supporting this research project are provided by NIHR Programme Grants for Applied Research (PGfAR) Recent publications https://www.ndcn.ox.ac.uk/research/experimental-and-clinicalsleep-medicine-group The role We are seeking a motivated post-doctoral research associate to join the Experimental and Clinical Sleep Medicine group within the Nuffield Department of Clinical Neurosciences. We conduct human experimental and clinical studies on sleep and disorders of sleep with the aim of understanding their pathophysiology and treatment. The post holder will work on a new programme grant funded by the National Institute for Health and Care Research (NIHR) aimed at developing and testing a novel behavioural intervention for shift-work sleep disorder in NHS workers. The post-holder will be part of a multi-disciplinary team comprising experts in sleep and circadian science, occupational medicine, health psychology, primary care, health economics, and clinical trial methodology. Principal duties include reviewing existing literature, developing novel intervention materials, training team members on intervention delivery, and co-ordinating a feasibility study to assess intervention acceptability. The post is fixed term until 31st December 2025, but with possibility of extension until 31st March 2028 following funder review. Informal enquiries are encouraged (simon.kyle@ndcn.ox.ac.uk). Responsibilities • Develop the content for a novel intervention for shift-work sleep disorder • Review published literature and work closely with our patient and public involvement advisory group to develop and refine intervention materials • Support participant recruitment and assessment, and data analysis • Publish and present research results to the international scientific community • Attend and present work at meetings with collaborators • Support the planning and running of sleep-lab studies taking place in the group • In the context of work above and resources available, with the support of the laboratory and supervisor, prepare for appropriate career advancement • Undertake other duties in the department from time to time as determined commensurate with the grade and responsibilities of this post, and any other reasonable request Selection criteria Essential selection criteria • • • • = Hold a PhD in neuroscience, psychology or related discipline, or have submitted a PhD thesis prior to taking up this appointment Expertise in the assessment of sleep disorders or circadian rhythm sleep-wake disorders Expertise in interventions for sleep disorders or circadian rhythm sleep-wake disorders Be able to demonstrate competence and success in the thesis research area (and postdoctoral work if appropriate) e.g. as judged by publications (including papers in press and publicly available preprints) in high quality peer-reviewed journals. Evidence will be sought of a deep understanding of the applicant's previous fields of research and evidence of independent intellectual and practical contributions to previous research projects. • • • • • • Have excellent interpersonal skills, including the ability to be comfortable and confident interacting with patients in a research study, team members, administrative staff, and the broader research community; be viewed as motivated and enthusiastic Able to demonstrate an ability to work flexibly with regard to duties and hours worked, with the priority being to meet the team research goals. Have previous experience of working within a multi-disciplinary team Strong academic record as demonstrated by grades achieved and awards received Show an ability to work supportively in a laboratory environment, and to supervise and educate junior co-workers and take part in joint projects through co-operation and the exchange of information and skills. Be willing to play a role in keeping the laboratory running by assuming a share of group responsibilities. Desirable selection criteria • • • • Previous experience of obtaining and maintaining regulatory and ethics approvals Expertise in shift-work and/or shift-work sleep disorder Expertise in sleep and circadian measurement and analysis (e.g., polysomnography, actigraphy, circadian phase markers) Experience of developing behavioural interventions Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. If you have previously worked for the University we will also verify key information such as your dates of employment and reason for leaving your previous role with the department/unit where you worked. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Additional security pre-employment checks This job includes duties that will require additional security pre-employment checks: • University security screening (eg identity checks) About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. = While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognized centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information visit: www.medsci.ox.ac.uk The Nuffield Department of Clinical Neurosciences The Nuffield Department of Clinical Neurosciences (NDCN), led by Prof Kevin Talbot, has over 400 staff and 150 postgraduate students. NDCN has an established research and teaching portfolio with a national and international reputation for excellence. NDCN is based in high quality research and clinical facilities in the West Wing of the John Radcliffe Hospital, alongside the Department's world-class Wellcome Centre for Integrative Neuroimaging (WIN) and the Weatherall Institute of Molecular Medicine (which houses 3 of our research groups), and provides the ideal facilities to translate research from bench to bedside. In keeping with the award of NIHR Comprehensive Biomedical Research Centre status, to a partnership between Oxford University and the Oxford Radcliffe Hospitals NHS Trust, we have developed a highly integrated and interdisciplinary environment in which research, teaching, clinical training and clinical care interact. This enables us to establish new approaches to the understanding, diagnosis and treatment of brain diseases. To this end the Department fosters collaborations worldwide and warmly welcomes visiting scientists, clinical fellows and students. The Department comprises six sections: For more information visit: www.ndcn.ox.ac.uk Medical Research Council Brain Network Dynamics Unit The MRC BNDU is directed by Professor Peter Magill and is exceptionally multidisciplinary, integrating research programmes that span clinical, experimental and computational neuroscience. The Unit’s collective goal is to understand and exploit the moment-to-moment interactions between nerve cells that are critical for brain functions, with a special focus on the brain circuits underlying movement and memory. For more information visit: www.mrcbndu.ox.ac.uk Nuffield Division of Anaesthesia NDA is led by Associate Professor Andrew Farmery. The NDA is committed to the development and maintenance of internationally competitive research programmes in pain and consciousness; respiration and hypoxia; adult and neuro-intensive care; simulation and human factors training. For more information visit www.nda.ox.ac.uk Division of Clinical Neurology DCN is led by Professor David Bennett. DCN is committed to the development of research programs that improve understanding of the nervous system in health and disease. = For more information visit www.dcn.ox.ac.uk The Wellcome Centre for Integrative Neuroimaging (WIN) WIN is a multi-disciplinary neuroimaging research facility led by Heidi Johansen-Berg. WIN aims to bridge the gap between laboratory neuroscience and human health, by performing multi-scale studies spanning from animal models through to human populations. It focuses on the use of Magnetic Resonance Imaging (MRI) for neuroscience research, along with related technologies such as Transcranial Magnetic Stimulation, transcranial Direct Current Stimulation, MEG and EEG. WIN has core locations at the John Radcliffe Hospital (FMRIB), Warneford Hospital (OHBA) and University Science area (BSB). For more information visit www.win.ox.ac.uk Nuffield Laboratory of Ophthalmology NLO is led by Professor Russell Foster, who leads the Sleep & Circadian Neuroscience Institute. NLO pursues scientific and clinical research into a range of areas related to vision, the eye and circadian neuroscience. For more information visit www.nlo.ox.ac.uk Centre for the Prevention of Stroke & Dementia CPSD is led by Professor Peter Rothwell. The centre carries out research that increases understanding of the causes of cerebrovascular disease. Its aims are to improve prevention of stroke and dementia by earlier diagnosis, more reliable prognostication, and more effective use of existing preventive treatments in routine clinical practice. For more information visit www.cpsd.ox.ac.uk Working at NDCN NDCN actively promotes a healthy work life balance amongst employees through a number of family friendly policies. See https://hr.admin.ox.ac.uk/staff-benefits for further information. The University of Oxford is a member of the Athena SWAN Charter and holds an institutional Bronze Athena SWAN award. The Department of Clinical Neurosciences holds a departmental Silver Athena award in recognition of its efforts to introduce organisational and cultural practices that promote advancement of gender equality: representation, progression and success for all. = How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly: recruitment@ndcn.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. = Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82 of 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. = Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependants. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency backup care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care The University has excellent childcare services, including five University nurseries as well as Universitysupported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. Oxford Research Staff Society (OxRSS) A society run by and for Oxford University research staff. It offers researchers a range of social and professional networking opportunities. Membership is free, and all researchers employed by Oxford University are welcome to join. Subscribe at researchstaff-subscribe@maillist.ox.ac.uk to join the mailing list to find out about upcoming events and other information for researchers, or contact the committee on committee@oxrss.ox.ac.uk. For more information, see www.ox.ac.uk/oxrss, Twitter @ResStaffOxford, and Facebook www.facebook.com/oxrss. =
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License
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has site
Standard Grade 8: £45,558 - £54,395 per annum. A less experienced candidate may be appointed at Grade 5: £28,759 – £33,966 per annum, with a commensurate adjustment in either the essential criteria, responsibilities or duties.
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Biotechnologist – Biomarkers in Neurodegeneration
West Wing, Level 6, John Radcliffe Hospital, Oxford, OX3 9DU Web: www.ndcn.ox.ac.uk | Tel: +44(0)1865 234702 | Email: recruitment@ndcn.ox.ac.uk Job title Admin Assistant Division Medical Sciences Division Department Nuffield Department of Clinical Neurosciences (NDCN) Location John Radcliffe Hospital, Headington, Oxford, OX3 9DU Grade and salary Grade 4: £25,138 – £28,759 per annum Hours Full time Contract type Fixed-term until 31st March 2025 Reporting to Prof. Michele Hu Vacancy reference 172332 Additional information Research topic European Platform for Neurodegenerative Disorders (EPND) and Parkinson’s Progression Marker Initiative (PPMI) Principal Investigator / supervisor Michele Hu Project team Oxford Parkinson’s Disease Centre Project web site https://www.dpag.ox.ac.uk/opdc Funding partner The funds supporting this research project are provided by IMI (Innovative Medicines Initiative), MJFF (Michael J Fox Foundation) and Parkinson’s UK Recent publications https://www.dpag.ox.ac.uk/publications The role This full-time post is based at the Oxford Parkinson’s Disease Centre Clinical Team (OPDC: https://www.dpag.ox.ac.uk/opdc) and the Nuffield Department of Clinical Neurosciences, Oxford University, John Radcliffe Hospital. The role will involve working with a number of key stakeholders at different levels to ensure the smooth running of the OPDC cohort. Following training and ongoing support, the post holder will need to manage their own workload effectively and autonomously. Working closely with the Clinical Project Manager and Clinical Lead. The role will be largely based at the John Radcliffe Hospital, Oxford however will remotely cover other sites involved in OPDC including Cambridge and Sheffield. Since its inception in 2010, the OPDC Discovery Cohort has longitudinally characterised over 1800 participants with early and prodromal Parkinson’s disease (PD), alongside control subjects. It is independently cited as a world-leading PD research biomarker cohort, generating over 200 related publications. Key cohort aims are to improve understanding of the biology of early Parkinson’s and identify predictors of Parkinson’s onset and subsequent progression. The Discovery cohort is seen as a beacon of excellence within Oxford Neuroscience, and is strongly committed to improving public engagement with research and promoting outreach activities. It exemplifies multi-disciplinary translational neuroscience in Oxford at its best, representing a close and interactive collaboration between research laboratories in the basic sciences with clinicians from the Nuffield Division of Clinical Neurology. This multidisciplinary approach has generated outstanding resources in clinical cohorts and characterised some of the best stem cell models in the world. This job post will involve working alongside the current OPDC research administrator to provide sufficient administrative and patient-facing support for the clinical cohort of the Oxford Parkinson’s Disease Centre (OPDC; https://www.dpag.ox.ac.uk/opdc). This post will involve working alongside 1 project manager (currently on maternity leave), 2-3 research practitioners/nurses, 1 research administrator, 2-3 Clinical Research Fellows (one senior CRF), 2 research statisticians, 1 digital research assistant, and study PI Michele Hu. All necessary training and supervision will be provided. The post roles include (but are not limited to) the below points: The post is funded for 12 months from 01.04.24 (or as soon as possible thereafter), with potential to extend beyond this following successful review and the applicant’s choice. Funding for this post is also subject to satisfactory annual review by MJFF, IMI and the Parkinson’s UK Cohort Study Review Council. Responsibilities • Act as a point of contact in the OPDC administration office (based on Level 6, West Wing, John Radcliffe Hospital Oxford) for students, staff and visitors. Answer phones and emails, respond to general enquiries interpreting university and external regulations as appropriate. • Make administrative arrangements for training and events including room bookings, catering, travel and accommodation arrangements for staff and study participants if required. • Organise mailings for training and events, maintain mailing lists. Compile agendas and draft minutes for team meetings alongside research administrator. • Collate and circulate appropriate data. Create and accurately maintain spreadsheets and other data tables to a precise standard. • Work with the PI, Project Manager and other administrative assistant to create, develop and maintain systems to ensure smooth running of the study across all sites. = • Communicate daily with study participants over the telephone and by email to book research clinic appointments, day case research procedures including lumbar puncture/skin biopsies, MRI appointments and/or DaT scan appointments, and to answer any queries about the OPDC and related PD trial studies. This also involves sending out appointment packs to participants, such as a cover letter and questionnaires, and potentially other clinical research packs (e.g. skin swabs). Setting up weekly to monthly John Radcliffe Hospital research clinics. • Prepare participant files. This includes ensuring correct consent forms, information sheet and any other paperwork is correct and ready for clinics. Assisting with the preparation, tracking and uploading of digital technologies to be used in clinics and by study participants (such as smartphones). Collecting paperwork after clinic and dealing with related administrative tasks, such as, but not limited to, participant travel expenses and data entry. • Procure according to set budgets if required, and assist the project manager/ finance administrator by processing invoices. • Deal sensitively and appropriately with all communications. Deal with a range of enquiries, taking appropriate action and liaising with the appropriate staff as necessary. • Maintain accurate systems to ensure activities and processes take place in a timely way. Organise own workload and act independently within appropriate guidelines and support. Supporting patient-facing Research Activity • Complete new and follow up visits according to the protocol at research sites, home visits and via telephone interview where applicable by individuals. • Provide support and signpost patients onwards to services as appropriate within the role. • Provide clinical ratings for other OPDC studies hosted at Oxford and upload digital data from a wearables study which assesses sleep, and commercial drug studies where appropriate. • Assist in the recruitment of participants to OPDC studies according to local targets, and support all other Discovery sites as required. • Take delegated responsibility in OPDC Discovery as required: carry out study procedures and global rating/detailed psychometric assessments. • Obtain blood, ECG readings, blood pressure readings and other general medical observations in clinical studies linked to OPDC. • Work effectively under the supervision of the PI and OPDC Senior CRF/Project Manager. • Communicate effectively with PI, cohort team and Project Manager. • Working within the OPDC cohort team to manage databases, ensuring high-quality data is collated. Timely and proactive response to data queries. = • Help promote patient engagement and study retention through personally contributing to OPDC cohort days, OPDC Newsletters, publicity events, and audit of patient satisfaction in research study participation. • Complete all relevant training as required including GCP, statutory/mandatoryhealthcare training, care certificate (if applicable), clinical assessment training and local inductions. Keep all training up-to-date as required. • Keep up-to-date with current legislation and research which affects role. • Support the planning and organisation of events for a variety of audiences (e.g. patients, public, funders, scientists or clinicians) including work shops and annual research cohort days, annual OPDC participant newsletters and updates. • Deal sensitively and appropriately in communications with patients, carers and members of the public. • Undertake other duties in the department from time to time as determined commensurate with the grade and responsibilities of this post, and any other reasonable request. Supervision and training • Will be provided to help maintain patient confidentiality at all times and in particular, the confidentiality of electronically stored personal data in line with the requirements of the Data Protection Act. • At all times to work according to current policies and research legislation and guidance. Selection criteria Essential selection criteria • Experience of managing administrative processes and reception or customer facing work. • The ability to work independently once fully trained, with a willingness to resolve situations, as well as knowing when to refer issues to others. • The ability to organise own workload and to work to deadlines, evidenced by formal qualifications at (for example BTEC ND, NVQ Level 3 or equivalent) and/or significant work experience at a similar level. • Ability to help organise events and make administrative arrangements. • Ability to use standard computer programs (Outlook, Word, Excel). • Previous experience of working as part of a team in an office environment, with a flexible and enthusiastic approach to working and using own initiative. = Desirable selection criteria • Experience of working within an HE institution or within a service industry environment. • Knowledge of current national systems and strictures for research in the NHS. • Administration experience in a clinical research environment. . Pre-employment screening Standard checks If you are offered the post, the offer will be subject to standard pre-employment checks. You will be asked to provide: proof of your right-to-work in the UK; proof of your identity; and (if we haven’t done so already) we will contact the referees you have nominated. If you have previously worked for the University we will also verify key information such as your dates of employment and reason for leaving your previous role with the department/unit where you worked. You will also be asked to complete a health declaration so that you can tell us about any health conditions or disabilities for which you may need us to make appropriate adjustments. Please read the candidate notes on the University’s pre-employment screening procedures at: https://www.jobs.ox.ac.uk/pre-employment-checks Hazard-specific / Safety-critical duties This job includes hazards or safety-critical activities. If you are offered the post, you will be asked to complete a health questionnaire which will be assessed by our Occupational Health Service, and the offer of employment will be subject a successful outcome of this assessment. The hazards or safety-critical duties involved are as follows: • Lone Working • Driving on University business Additional security pre-employment checks This job includes duties that will require additional security pre-employment checks: • List duties associated with the required security checks • University security screening (eg identity checks) About the University of Oxford Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. = While we have long traditions of scholarship, we are also forward-looking, creative and cuttingedge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spin-outs, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation. Medical Sciences Division The Medical Sciences Division is an internationally recognized centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. World-leading programmes, housed in state-of-the-art facilities, cover the full range of scientific endeavour from the molecule to the population. With our NHS partners we also foster the highest possible standards in patient care. For more information visit: www.medsci.ox.ac.uk The Nuffield Department of Clinical Neurosciences The Nuffield Department of Clinical Neurosciences (NDCN), led by Prof Kevin Talbot, has over 400 staff and 150 postgraduate students. NDCN has an established research and teaching portfolio with a national and international reputation for excellence. NDCN is based in high quality research and clinical facilities in the West Wing of the John Radcliffe Hospital, alongside the Department's world-class Wellcome Centre for Integrative Neuroimaging (WIN) and the Weatherall Institute of Molecular Medicine (which houses 3 of our research groups), and provides the ideal facilities to translate research from bench to bedside. In keeping with the award of NIHR Comprehensive Biomedical Research Centre status, to a partnership between Oxford University and the Oxford Radcliffe Hospitals NHS Trust, we have developed a highly integrated and interdisciplinary environment in which research, teaching, clinical training and clinical care interact. This enables us to establish new approaches to the understanding, diagnosis and treatment of brain diseases. To this end the Department fosters collaborations worldwide and warmly welcomes visiting scientists, clinical fellows and students. The Department comprises six sections: For more information visit: www.ndcn.ox.ac.uk Medical Research Council Brain Network Dynamics Unit The MRC BNDU is directed by Professor Peter Magill and is exceptionally multidisciplinary, integrating research programmes that span clinical, experimental and computational neuroscience. The Unit’s collective goal is to understand and exploit the moment-to-moment interactions between nerve cells that are critical for brain functions, with a special focus on the brain circuits underlying movement and memory. For more information visit: www.mrcbndu.ox.ac.uk Nuffield Division of Anaesthesia NDA is led by Associate Professor Andrew Farmery. The NDA is committed to the development and maintenance of internationally competitive research programmes in pain and consciousness; respiration and hypoxia; adult and neuro-intensive care; simulation and human factors training. For more information visit www.nda.ox.ac.uk = Division of Clinical Neurology DCN is led by Professor David Bennett. DCN is committed to the development of research programs that improve understanding of the nervous system in health and disease. For more information visit www.dcn.ox.ac.uk The Wellcome Centre for Integrative Neuroimaging (WIN) WIN is a multi-disciplinary neuroimaging research facility led by Heidi Johansen-Berg. WIN aims to bridge the gap between laboratory neuroscience and human health, by performing multi-scale studies spanning from animal models through to human populations. It focuses on the use of Magnetic Resonance Imaging (MRI) for neuroscience research, along with related technologies such as Transcranial Magnetic Stimulation, transcranial Direct Current Stimulation, MEG and EEG. WIN has core locations at the John Radcliffe Hospital (FMRIB), Warneford Hospital (OHBA) and University Science area (BSB). For more information visit www.win.ox.ac.uk Nuffield Laboratory of Ophthalmology NLO is led by Professor Russell Foster, who leads the Sleep & Circadian Neuroscience Institute. NLO pursues scientific and clinical research into a range of areas related to vision, the eye and circadian neuroscience. For more information visit www.nlo.ox.ac.uk Centre for the Prevention of Stroke & Dementia CPSD is led by Professor Peter Rothwell. The centre carries out research that increases understanding of the causes of cerebrovascular disease. Its aims are to improve prevention of stroke and dementia by earlier diagnosis, more reliable prognostication, and more effective use of existing preventive treatments in routine clinical practice. For more information visit www.cpsd.ox.ac.uk Working at NDCN NDCN actively promotes a healthy work life balance amongst employees through a number of family friendly policies. See https://hr.admin.ox.ac.uk/staff-benefits for further information. The University of Oxford is a member of the Athena SWAN Charter and holds an institutional Bronze Athena SWAN award. The Department of Clinical Neurosciences holds a departmental Silver Athena award in recognition of its efforts to introduce organisational and cultural practices that promote advancement of gender equality: representation, progression and success for all. How to apply Applications are made through our online recruitment portal. Information about how to apply is available on our Jobs website https://www.jobs.ox.ac.uk/how-to-apply. Your application will be judged solely on the basis of how you demonstrate that you meet the selection criteria stated in the job description. As part of your application you will be asked to provide details of two referees and indicate whether we can contact them now. You will be asked to upload a CV and a supporting statement. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks (such as time out to care for dependants) = Please upload all documents as PDF files with your name and the document type in the filename. All applications must be received by midday UK time on the closing date stated in the online advertisement. Information for priority candidates A priority candidate is a University employee who is seeking redeployment because they have been advised that they are at risk of redundancy, or on grounds of ill-health/disability. Priority candidates are issued with a redeployment letter by their employing department(s). If you are a priority candidate, please ensure that you attach your redeployment letter to your application (or email it to the contact address on the advert if the application form used for the vacancy does not allow attachments). If you need help Application FAQs, including technical troubleshooting advice is available at: https://staff.web.ox.ac.uk/recruitment-support-faqs. Non-technical questions about this job should be addressed to the recruiting department directly: recruitment@ndcn.ox.ac.uk. To return to the online application at any stage, please go to: www.recruit.ox.ac.uk. Please note that you will receive an automated email from our online recruitment portal to confirm receipt of your application. Please check your spam/junk mail if you do not receive this email. Important information for candidates Data Privacy Please note that any personal data submitted to the University as part of the job application process will be processed in accordance with the GDPR and related UK data protection legislation. For further information, please see the University’s Privacy Notice for Job Applicants at: https://compliance.admin.ox.ac.uk/job-applicant-privacy-policy. The University’s Policy on Data Protection is available at: https://compliance.admin.ox.ac.uk/data-protection-policy. The University’s policy on retirement The University operates an Employer Justified Retirement Age (EJRA) for very senior research posts at grade RSIV/D35 and clinical equivalents E62 and E82 of 30 September before the 70th birthday. The justification for this is explained at: https://hr.admin.ox.ac.uk/the-ejra. For existing employees on these grades, any employment beyond the retirement age is subject to approval through the procedures: https://hr.admin.ox.ac.uk/the-ejra. There is no normal or fixed age at which staff in posts at other grades have to retire. Staff at these grades may elect to retire in accordance with the rules of the applicable pension scheme, as may be amended from time to time. Equality of opportunity Entry into employment with the University and progression within employment will be determined only by personal merit and the application of criteria which are related to the duties = of each particular post and the relevant salary structure. In all cases, ability to perform the job will be the primary consideration. No applicant or member of staff shall be discriminated against because of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation. = Benefits of working at the University Employee benefits University employees enjoy 38 days’ paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. See https://hr.admin.ox.ac.uk/staff-benefits University Club and sports facilities Membership of the University Club is free for all University staff. The University Club offers social, sporting, and hospitality facilities. Staff can also use the University Sports Centre on Iffley Road at discounted rates, including a fitness centre, powerlifting room, and swimming pool. See www.club.ox.ac.uk and https://www.sport.ox.ac.uk/. Information for staff new to Oxford If you are relocating to Oxfordshire from overseas or elsewhere in the UK, the University's Welcome Service website includes practical information about settling in the area, including advice on relocation, accommodation, and local schools. See https://welcome.ox.ac.uk/ There is also a visa loan scheme to cover the costs of UK visa applications for staff and their dependants. See https://staffimmigration.admin.ox.ac.uk/visa-loan-scheme Family-friendly benefits With one of the most generous family leave schemes in the Higher Education sector, and a range of flexible working options, Oxford aims to be a family-friendly employer. We also subscribe to the Work+Family Space, a service that provides practical advice and support for employees who have caring responsibilities. The service offers a free telephone advice line, and the ability to book emergency backup care for children, adult dependents and elderly relatives. See https://hr.admin.ox.ac.uk/my-family-care The University has excellent childcare services, including five University nurseries as well as Universitysupported places at many other private nurseries. For full details, including how to apply and the costs, see https://childcare.admin.ox.ac.uk/ Disabled staff We are committed to supporting members of staff with disabilities or long-term health conditions. For further details, including information about how to make contact, in confidence, with the University’s Staff Disability Advisor, see https://edu.admin.ox.ac.uk/disability-support Staff networks The University has a number of staff networks including the Oxford Research Staff Society, BME staff network, LGBT+ staff network and a disabled staff network. You can find more information at https://edu.admin.ox.ac.uk/networks The University of Oxford Newcomers' Club The University of Oxford Newcomers' Club is an organisation run by volunteers that aims to assist the partners of new staff settle into Oxford, and provides them with an opportunity to meet people and make connections in the local area. See www.newcomers.ox.ac.uk. Oxford Research Staff Society (OxRSS) A society run by and for Oxford University research staff. It offers researchers a range of social and professional networking opportunities. Membership is free, and all researchers employed by Oxford University are welcome to join. Subscribe at researchstaff-subscribe@maillist.ox.ac.uk to join the mailing list to find out about upcoming events and other information for researchers, or contact the committee on committee@oxrss.ox.ac.uk. For more information, see www.ox.ac.uk/oxrss, Twitter @ResStaffOxford, and Facebook www.facebook.com/oxrss. =
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Level 6, West Wing, John Radcliffe Hospital, Headley Way
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