171055 Department of Oncology, University of Oxford http://www.oncology.ox.ac.uk/ https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_recruitment_id=171055&p_display_in_irish=N&p_company=10&p_internal_external=E&p_applicant_no=&p_process_type=&p_refresh_search=Y&p_form_profile_detail=&p_display_apply_ind=Y <div><p><em>Salary: Standard Grade 8: &#163;45,585 - &#163;54,395 per annum</em></p> <p></p><div><strong>About the role</strong></div><br> <div>An exciting opportunity has arisen for a Senior Computational Biologist within the Department of Oncology, based in the Oxford Molecular Diagnostics Centre.</div><br> <div>One of it's emphases is on clinical applications of novel genomics technologies, in particular next generation sequencing and array-based methods.&#160; The results of this programme are already being translated to the clinic. Particular focus is currently on cancer, haematology and inherited disorders.</div><br> <div>The interdisciplinary nature of the Department of Oncology and of the Oxford Molecular Diagnostics Centre involves a diverse and stimulating array of challenges relating to biology, sequence analysis, statistics, computer programming and the application of these to clinical questions. This, combined with collaborations across Oxford&#8217;s CRUK Cancer Centre and the Oxford Centre of Early Cancer Detection (OxCode) provides an active and rich research environment.</div><br> <div>You will be responsible for scientifically leading the chronic lymphocytic leukaemia (CLL) related cancer genomics projects. You will work with a small group of data scientists to develop a molecular risk score for disease progression from pre-malignancy using a large data set of whole genome tumour-normal pairs. In addition, you will be involved in applying tools for neo-epitope prediction of CLL from transcriptome sequencing. You will be familiar with working in the Genomics England&#8217;s data environment. You will apply analysis methods and where appropriate, develop novel methods and algorithms, and work on setting up and maintaining the necessary data processing pipelines. You will work closely with multi-disciplinary project teams, encompassing laboratory scientists and clinicians and other data scientists on the Oxford Campus.</div><br> <div>This is a full-time post, fixed-term for 1 year in first instance.</div><br> <div>&#160;</div><br> <div><strong>About You</strong></div><br> <div>You must hold a PhD in Bioinformatics, Statistical Genetics or similar discipline, along with deep understanding of CLL genomics evidenced by high-impact publications. You will have previous overseas postdoctoral experience in an internationally renowned institution in applied DNA sequence analysis or a directly comparable field. Demonstrable programming skills in languages such as Python, Java, C/C++, R or similar and ability to assess new developments in bioinformatics are essential. You will have early evidence of the ability to lead a team scientifically and a proven track record of managing international collaborations effectively, as well as previous experience of directly supervising students. A Strong academic publication record in peer-reviewed journals and previous experience of cancer sequence analysis would be advantageous.</div><br> <div>&#160;</div><br> <div><strong>Application Process</strong></div><br> <div>If you would like to discuss this role please contact Professor Anna Schuh on &#160;<a href="mailto:anna.schuh@oncology.ox.ac.uk">anna.schuh@oncology.ox.ac.uk</a></div><br> <div>You will be required to upload a supporting statement (setting out how you meet the selection criteria), a curriculum vitae and the names and contact details of two referees as part of your online application.</div><br> <div>&#160;</div><br> <div>The closing date for applications is <strong>12.00 noon on 3 April 2024</strong>.</div><br> <div>&#160;</div><br> <div>Interviews are expected to take place w/c 22th April 2024. Candidates should be available for interview during this time.</div><br> <div>&#160;</div><br> <div><strong>Committed to equality and valuing diversity</strong></div> </div> Senior Computational Biologist 2024-02-14 2024-04-03
Oxford United Kingdom
171861 Department of Oncology, University of Oxford http://www.oncology.ox.ac.uk/ https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_recruitment_id=171861&p_display_in_irish=N&p_company=10&p_internal_external=E&p_applicant_no=&p_process_type=&p_refresh_search=Y&p_form_profile_detail=&p_display_apply_ind=Y <div><p><em>Salary: Standard Grade 4: &#163;25,138 - &#163;28,759 p.a.</em></p> <p></p><div><strong>About the role</strong></div><br> <div>&#160;</div><br> <div>We have an exciting opportunity for a Clinical Trial Assistant to join the Early Phase Clinical Trials Unit (EPCTU) within the Cancer and Haematology Centre at the Churchill Hospital in Oxford. The unit recruits approximately 150 patients each year onto Early Phase (phase I/II) oncology and haematology trials.</div><br> <div>&#160;</div><br> <div>This post is suited to someone wishing to embark on a career path focused on clinical trials. You will assist in specialised clinical data management within the unit&#8217;s Data Management Team. The primary responsibility is completion of case report forms (CRFs) to record medical research data.&#160;&#160; You will be required work closely with the unit&#8217;s clinical staff to resolve subsequent data queries.&#160; You will also be responsible for organising and hosting monitoring visits required by trial sponsors.</div><br> <div>&#160;</div><br> <div>In addition, you will provide some administrative support to the research nursing team. This will involve; organising screening appointments, admissions and tests that are mandated by the research protocol and communicating appointment and admission related information to patients and carers;&#160; management of trial specific regulatory documentation, such as delegation and training logs, creation of trial specific work sheets, upkeep and filing of documentation in investigator site files in line with the unit&#8217;s standard operating procedures; acting as a central point of communication, disseminating to the nurses and other healthcare professionals as appropriate.</div><br> <div>&#160;</div><br> <div>The post is based in the Early Phase Clinical Trial Unit, Churchill Hospital, Oxford, OX3 7LE and is offered on a full-time basis, fixed term for one year.</div><br> <div>&#160;</div><br> <div>You will be required to apply for and obtain an NHS Honorary Contract to undertake this role.</div><br> <div>&#160;</div><br> <div><strong>About you</strong></div><br> <div>&#160;</div><br> <div>You will be educated to GCSE level or equivalent and have advanced Office and IT skills for document management, information processing and communication. You will be a good team player but equally capable of working well on your own initiative, together with sound communication (written and verbal English) skills. You will be organised and methodical, able to prioritise and work well under pressure, with a positive approach. You will have the ability to exercise discretion and handle confidential information appropriately, applying accuracy and attention to detail in all aspects of your work. Experience of working in a regulatory environment would be advantageous.</div><br> <div>&#160;</div><br> <div><strong>Application Process</strong></div><br> <div>&#160;</div><br> <div>You will be required to upload a supporting statement (setting out how you meet the selection criteria) and the names and contact details of two referees as part of your online application.</div><br> <div>&#160;</div><br> <div>Only applications received by 12 pm on Monday 8th April 2024 will be considered.</div><br> <div>&#160;</div><br> <div><strong>Committed to equality and valuing diversity</strong></div> </div> Clinical Trial Assistant 2024-03-25 2024-04-08
Oxford United Kingdom
171621 Department of Oncology, University of Oxford http://www.oncology.ox.ac.uk/ https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_recruitment_id=171621&p_display_in_irish=N&p_company=10&p_internal_external=E&p_applicant_no=&p_process_type=&p_refresh_search=Y&p_form_profile_detail=&p_display_apply_ind=Y <div><p><em>Salary: Standard Grade 5: &#163;28,759 - &#163;33,966 per annum</em></p> <p></p><div><strong>About the role</strong></div><br> <div>We have an exciting opportunity for a Clinical Trial Administrator (CTA) (maternity cover) to join the Oncology Clinical Trials Office (OCTO), working in a team of trial management professionals, running clinical trials and studies across a varied portfolio. The post holder will be responsible for a range of activities required in the day-to-day running of clinical trials. CTAs will usually work on 1-3 trials, offering the opportunity to be involved in and learn about a wide range of clinical trial management activities. OCTO is based in the Department of Oncology, University of Oxford. OCTO develops and runs academic clinical trials and studies and is proactive in improving clinical trial procedures. Working to the highest standards our trials are concerned with the practical application of high-quality clinical research into early detection and prevention strategies &#160;and innovative and effective cancer therapies. This post is a maternity cover for 12 months and is offered full-time, although part-time hours (minimum of 80% FTE, worked over no fewer than four days a week) may be considered.</div><br> <div>&#160;</div><br> <div>The post is based in Oncology Clinical Trials Office (OCTO), Level 2, Cancer &amp; Haematology Department, Churchill Hospital, Headington, Oxford, OX3 7LE. Due to the location, you will be required to apply for and obtain an NHS Honorary Contract in order to carry out this role. There will be the occasional need to travel to participating hospitals or national meetings (approximately twice a year, sometimes with the need for overnight stays).</div><br> <div>&#160;</div><br> <div><strong>About you</strong></div><br> <div>You will be educated to at least A-level in a biomedical or associated subject (or other relevant qualification) and have previous experience in a clinical research setting, with an understanding of Good Clinical Practice (GCP). You will have experience of managing and working with clinical research or patient data e.g. data entry, data coding, entry validation and reporting, with critical and intelligent attention to detail and high standards of accuracy. You will have effective communication and inter-personal skills, including written and spoken English, and strong administrative skills including email, minute-taking, and use of Microsoft Office (Word, Excel, PowerPoint). Experience of working on oncology clinical trials in a non-commercial setting would be advantageous.</div><br> <div>&#160;</div><br> <div><strong>Application process</strong></div><br> <div>If you would like to discuss this role please contact Linda Collins on &#160;<a href="mailto:linda.collins@oncology.ox.ac.uk">linda.collins@oncology.ox.ac.uk</a>. You will be required to upload a supporting statement (setting out how you meet the selection criteria), a curriculum vitae and the names and contact details of two referees as part of your online application. The closing date for applications is 12.00 noon on Tuesday 9th April 2024.</div><br> <div>&#160;</div><br> <div><strong>Committed to equality and valuing diversity</strong></div> </div> Clinical Trial Administrator (Maternity Cover) 2024-03-08 2024-04-09
Oxford United Kingdom
171831 Department of Oncology, University of Oxford http://www.oncology.ox.ac.uk/ https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_recruitment_id=171831&p_display_in_irish=N&p_company=10&p_internal_external=E&p_applicant_no=&p_process_type=&p_refresh_search=Y&p_form_profile_detail=&p_display_apply_ind=Y <div><p><em>Salary: Standard Grade 7: &#163;36,024 - &#163;44,263</em></p> <p></p><div><strong>About the role</strong></div><br> <div>&#160;</div><br> <div>Join the dynamic team led by Professor Geoff Higgins in the Department of Oncology at the University of Oxford. This is an exceptional opportunity for a driven individual to contribute to ground-breaking research aimed at enhancing the effectiveness of radiotherapy treatments.</div><br> <div>&#160;</div><br> <div>Our focus lies in developing innovative approaches to sensitize tumor cells to radiotherapy, with the ultimate goal of improving patient outcomes while minimizing side effects. As a Postdoctoral Researcher, you will spearhead your own project within our broader research program.</div><br> <div>&#160;</div><br> <div>Your responsibilities will encompass discovering and characterizing novel therapeutic strategies, utilizing a diverse array of techniques including high-throughput screening, gene editing, cell death assays, and in vivo cancer models. Additionally, you will provide mentorship to junior team members, contribute to manuscript preparation and grant applications, and present findings at scientific conferences.</div><br> <div>&#160;</div><br> <div>The post will be based at the Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ, and is offered full-time, fixed-term until 31st October 2025 in the first instance.</div><br> <div>&#160;</div><br> <div><strong>About you</strong></div><br> <div>&#160;</div><br> <div>As the successful candidate for this position, you will hold or be close to completing a relevant PhD/DPhil in cell biology, molecular biology, biomedicine, or a related discipline. You will have specialized knowledge in the cell and molecular biology of cancer, a high level of technical competence, and substantial experience in standard molecular and cell biology techniques.</div><br> <div>You will demonstrate the ability to independently plan, develop, and manage a research project, contributing innovative ideas for new research projects and generating research income. Your excellent communication skills will enable you to write for publication, present research proposals and results, and represent the research group at meetings. Additionally, your track record of first-author publications in scientific journals and experience in supervising students and less experienced lab members will be invaluable.</div><br> <div>In addition to the essential qualifications, desirable attributes include a strong background in radiation biology and DNA repair mechanisms, previous experience working with mouse in vivo models, and knowledge in target discovery and drug development. Holding a Home Office personal license (PIL) for animal experimentation would also be advantageous.</div><br> <div>&#160;</div><br> <div><strong>Application Process</strong></div><br> <div>&#160;</div><br> <div>If you would like to discuss this role informally please contact Professor Geoff Higgins at &#160;<a href="mailto:geoffrey.higgins@oncology.ox.ac.uk">geoffrey.higgins@oncology.ox.ac.uk</a></div><br> <div>&#160;</div><br> <div>You will be required to upload a supporting statement (setting out how you meet the selection criteria), a curriculum vitae and the names and contact details of two referees as part of your online application. The closing date for applications is Thursday, 11th April 2024</div><br> <div>&#160;</div><br> <div>Interviews are expected to take place on Monday, 22nd April 2024. Candidates should be available for interviews during this time.</div><br> <div>&#160;</div><br> <div><strong>Committed to equality and valuing diversity</strong></div><br> <div>&#160;</div> </div> Postdoctoral Researcher 2024-03-21 2024-04-11
Oxford United Kingdom
171758 Department of Oncology, University of Oxford http://www.oncology.ox.ac.uk/ https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_recruitment_id=171758&p_display_in_irish=N&p_company=10&p_internal_external=E&p_applicant_no=&p_process_type=&p_refresh_search=Y&p_form_profile_detail=&p_display_apply_ind=Y <div><p><em>Salary: Standard Grade 5: &#163;28,759 - &#163;33,966</em></p> <p></p><div><strong></strong>**** Please note this is a re-advertisement and previous applicants need not apply<strong>&#160;****</strong></div><br> <div>&#160;</div><br> <div><strong>About the role</strong></div><br> <div>&#160;</div><br> <div>We have an exciting opportunity to join the facilities team as Facilities Support Officer. You will play an important role in supporting the Building and Facilities Manager to ensure that first-class research support is maintained within the Department of Oncology.</div><br> <div>&#160;</div><br> <div>This role provides support mainly within the Old Road Campus Research Building, at the nearby Radiobiology Research Institute (RRI) and the Weatherall Institute for Molecular Medicine (WIMM) however there is the possibility that support may be required at discrete times at other departmental locations. Providing day-to-day, front-line general support with no immediate supervision, the post holder will be expected to respond to enquiries and be responsible for resolving practical and technical issues.</div><br> <div>&#160;</div><br> <div><strong>About you</strong></div><br> <div>&#160;</div><br> <div>The successful candidate will be educated to at least A-level standard or equivalent, preferably in a science subject, demonstrate experience in a practical research or hospital laboratory environment and of practical problem-solving and troubleshooting combined with a willingness to contribute ideas in developing support provided by the team. Knowledge of current Health and Safety requirements within a practical research environment is essential along with excellent communications skills and a can-do attitude. Experience in a similar role and a working knowledge of scientific research environments is desirable.</div><br> <div>&#160;</div><br> <div>This is a full-time, permanent post, working 36.5 hours per week.</div><br> <div>&#160;</div><br> <div><strong>Application Process</strong></div><br> <div>&#160;</div><br> <div>You will be required to upload a supporting statement (setting out how you meet the selection criteria), a curriculum vitae and the names and contact details of two referees as part of your online application.</div><br> <div>&#160;</div><br> <div>Only applications received online by 12.00 midday (BST/GMT) on Monday, 15 April 2024 can be considered. Interviews are expected to take place during week commencing Monday 22 April 2024.</div><br> <div>&#160;</div><br> <div><strong>Committed to equality and valuing diversity</strong></div> </div> Facilities Support Officer 2024-03-18 2024-04-15
Oxford United Kingdom