_:N9541117b1a1e4ae4adcbca126c521337 "Headington" . . "notation"@en . """**Contract type:** **Fixed-term contract until 30th June 2026** **Hours: Full-time** **About the role** We are looking for a postdoctoral researcher to work in Translational Research Immunology Group (TRIG) on translational, collaborative project funded by EU. You will be placed in the Institute of Developmental and Regenerative Medicine on the Old Road Campus working in a close collaboration with the Oxford Kidney Pathology group. You will be part of a bigger EU-funded project which goal is to develop a safe and efficient cell therapy based on genome edited T cells for IgA nephropathy (IgAN). IgAN is the most common glomerulonephritis; IgA-rich complexes are deposited in renal glomeruli, leading to renal failure a third of cases, but there are currently no effective treatments, so this an area of significant unmet need. Redirected T cells offer the potential to specifically target pathogenic IgA1 producing cells. You will work closely with members of TRIG and Oxford Kidney Pathology groups, including students, other post-docs and research assistants as well as international collaborators within the EU consortium. You will be responsible for testing T cell therapeutics developed by our consortium, using in vivo models of glomerular immune complex disease as well as the establishment of a novel model for IgA Nephropathy. Additionally, you will contribute to spatial transcriptomics and proteomics in human IgAN kidney samples. **About you** You will hold a PhD (or be near to completion: thesis submitted) in a relevant area at the time of application and will have extensive experience in immunology or kidney disease field. Experience with cell culture techniques, animal models, molecular techniques is required. . You will have demonstrated the ability to work independently within projects, with the ability to communicate results clearly and succinctly in presentations, manuscripts and grant applications. Experience with flow cytometry and genetic editing techniques as well as knowledge of kidney disease are desirable. This full-time post is available immediately and is fixed-term until June 2026 in the first instance. **Application Process** If you would like to discuss this role, please contact Fadi Issa, fadi.issa@nds.ox.ac.uk. Applications for this vacancy are to be made online. You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application. Please quote reference **NDSA926** on all correspondence. Only applications received before **noon 10 May 2024** can be considered. Interviews will be held on Friday 24 May 2024. **Committed to equality and valuing diversity** """ . . . "John Radcliffe Hospital - Main Building" . . "Clinical Data Manager" . . _:N06ea44737efa4856ae90d582f6fb0e1d . . "Is Part Of"@en . "OxPoints"@en . "Address"@en . "172383"^^ . . . "Standard Grade 7: £36,024 - £44,263 per annum" . "preferred label"@en . _:N06ea44737efa4856ae90d582f6fb0e1d "+44-1865-270000" . _:N6f854e537b1f43679e122fc376b80dde . . . . . "2024-05-20T12:00:00+01:00"^^ . . . "HJ" . . . . "site principal"@fr . "2024-04-24T10:15:00+01:00"^^ . "Surgical Sciences, Nuffield Department of" . _:N9541117b1a1e4ae4adcbca126c521337 "United Kingdom" . . . . _:N9541117b1a1e4ae4adcbca126c521337 . . . . . . . "01865 612299" . . "John Radcliffe Hospital - Main Building" . . "subOrganization of"@en . . "2024-04-25T09:00:00+01:00"^^ . . . . . . . . "Medical Sciences Division" . "ha sede"@it . . _:Nb41459a1600443cd96b45605f7ee63b4 "United Kingdom" . _:N58ce392bdba948ecada830eb37046ebf . . . "name" . "Source"@en . . _:Nb41459a1600443cd96b45605f7ee63b4 . . _:N9541117b1a1e4ae4adcbca126c521337 . . . "Claire Wheeler" . "Medical Sciences Division" . "email"@en . . . . . . _:N58ce392bdba948ecada830eb37046ebf . . _:N9541117b1a1e4ae4adcbca126c521337 "John Radcliffe Hospital, Headley Way" . "2B06" . "postal code"@en . "NDSA930 - Trial Coordinator JD.doc" . "Fax"@en . "23232722"^^ . . "a un site"@fr . "Institute Of Developmental & Regenerative Medicine, Old Road Campus, Headington" . . "Standard Grade 6: £32,332 - £38,205 per annum" . . "sotto-Organization di"@it . . . "value" . "University of Oxford" . """

Contract type: Fixed-term contract until 30th June 2026

Hours: Full-time

 

About the role

We are looking for a postdoctoral researcher to work in Translational Research Immunology Group (TRIG) on translational, collaborative project funded by EU.  You will be placed in the Institute of Developmental and Regenerative Medicine on the Old Road Campus working in a close collaboration with the Oxford Kidney Pathology group.

 

You will be part of a bigger EU-funded project which goal is to develop a safe and efficient cell therapy based on genome edited T cells for IgA nephropathy (IgAN). IgAN is the most common glomerulonephritis; IgA-rich complexes are deposited in renal glomeruli, leading to renal failure a third of cases, but there are currently no effective treatments, so this an area of significant unmet need. Redirected T cells offer the potential to specifically target pathogenic IgA1 producing cells.

 

You will work closely with members of TRIG and Oxford Kidney Pathology groups, including students, other post-docs and research assistants as well as international collaborators within the EU consortium.  You will be responsible for testing T cell therapeutics developed by our consortium, using in vivo models of glomerular immune complex disease as well as the establishment of a novel model for IgA Nephropathy.  Additionally, you will contribute to spatial transcriptomics and proteomics in human IgAN kidney samples.

 

About you

You will hold a PhD (or be near to completion: thesis submitted) in a relevant area at the time of application and will have extensive experience in immunology or kidney disease field.  Experience with cell culture techniques, animal models, molecular techniques is required.  . You will have demonstrated the ability to work independently within projects, with the ability to communicate results clearly and succinctly in presentations, manuscripts and grant applications.  Experience with flow cytometry and genetic editing techniques as well as knowledge of kidney disease are desirable.

 

This full-time post is available immediately and is fixed-term until June 2026 in the first instance.

 

Application Process

If you would like to discuss this role, please contact Fadi Issa, fadi.issa@nds.ox.ac.uk.

 

Applications for this vacancy are to be made online. You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application. Please quote reference NDSA926 on all correspondence.

 

Only applications received before noon 10 May 2024 can be considered.

 

Interviews will be held on Friday 24 May 2024.

 

Committed to equality and valuing diversity
"""^^ . . . _:N6f854e537b1f43679e122fc376b80dde "+44-1865-270708" . "street address"@en . . . . . . "Postdoctoral Researcher in Cellular Therapeutics" . _:N9541117b1a1e4ae4adcbca126c521337 "OX3 9DU" . . "License"@en . . . . "Surgical Intervention Trials Unit, Botnar Research Centre, Old Road, OX3 7LD" . _:N6f854e537b1f43679e122fc376b80dde . "has site"@en . . . . . "Subject"@en . "Professor Fadi Issa" . "John Radcliffe West Wing and Children's Hospital" . . . . "172386"^^ . "2024-05-21T12:00:00+01:00"^^ . "surg"^^ . . . "true"^^ . . . "page" . . "address"@en . . . . . . . . . "false"^^ . . "false"^^ . "based near" . "university" . "primary Site"@en . . . "occupies" . "homepage" . . . . "department" . . . . . . _:Nb41459a1600443cd96b45605f7ee63b4 "University of Oxford" . . . "John Radcliffe West Wing and Children's Hospital" . . "2024-05-20T12:00:00+01:00"^^ . "Past vacancies at the University of Oxford" . """

Contract type: Fixed term until 02 January 2025

Hours: Full-time

 

About the role

We are looking for an enthusiastic Clinical Trial Coordinator to join the Surgical Intervention Trials Unit (SITU), working within a multi-disciplinary environment in order to develop, implement and run clinical trial activities. You will be based at the Botnar Research Centre in Headington, Oxford but you will be able to agree a pattern of regular remote working with your line manager.

 

The Clinical Trial Coordinator will join the established Trial Management Team within SITU, supporting the activities of the clinical trials and working closely with trial managers and data managers. This post will involve ensuring the effective conduct of the study in accordance with the trial protocol and regulatory and institutional procedures where appropriate. You will manage the trial email account, maintain trial files and will help manage activities of the participating clinical centres, which may include conducting site visits and addressing training needs where appropriate.

 

About you 

The successful candidate will be educated to A level or equivalent in English, Maths and a Science related subject. You will have previous experience in clinical research and working knowledge of the relevant ethical, legislative and research governance requirements relevant to clinical trials as well as familiarity with medical terminology. Excellent communication skills are essential as well as good organisational and problem-solving skills. You will have excellent communication and interpersonal skills with the ability to self-motivate and work well within a team environment. A willingness to travel to trial sites and meetings nationally is essential.

 

This full-time post is available immediately and is fixed-term until 2nd January 2025 in the first instance. We would be willing to consider applications for part-time hours. 

 

Application Process

If you would like to discuss this role, please contact the NDS SITU Operational Lead, Amy Taylor at op.lead@nds.ox.ac.uk

 

Applications for this vacancy are to be made online. You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application. Please quote reference NDSA930 on all correspondence. 

 

Only applications received before noon Tuesday 21st May 2024 can be considered.

 

Interviews will be held on Thursday 30th May 2024.

 

Committed to equality and valuing diversity
"""^^ . . "OxPoints"@en . . "Current vacancies at the University of Oxford" . . . . . . . . "2024-05-21T12:00:00+01:00"^^ . "HJ"^^ . "Standard Grade 6: £32,332 - £38,205 per annum" . . . . . "2024-05-10T12:00:00+01:00"^^ . "country name"@en . "Churchill OCDEM 1" . "locality"@en . "2024-04-29T12:00:00+01:00"^^ . _:N58ce392bdba948ecada830eb37046ebf . . . "Nuffield Department of Surgical Sciences" . . . . "sede principale"@it . . "false"^^ . . "Botnar Research Centre" . . . "Oxford, University of" . "extended address"@en . "telephone"@en . "Churchill OCDEM 1" . . . . . "tiene sede en"@es . "account" . "Old Road Campus Research Building" . . . . _:Nb41459a1600443cd96b45605f7ee63b4 "Oxford" . . . . . . . _:Nb41459a1600443cd96b45605f7ee63b4 "OX1 2JD" . "logo" . "es suborganización de"@es . . "type" . . "Old Road Campus Research Building" . . . . "00000000"^^ . . . "finance code" . . . "Unit price specification"@en . . . "Claire Wheeler" . . "surg" . "Agent" . . . . "171875"^^ . . . . "false"^^ . "valid through (0..1)"@en . "2024-05-10T12:00:00+01:00"^^ . . "label" . . . . _:Nb41459a1600443cd96b45605f7ee63b4 "Wellington Square" . . . . . . _:Nb41459a1600443cd96b45605f7ee63b4 . "Surgical Intervention Trials Unit, Botnar Research Centre, Windmill Road, OX3 7LD" . . """

Contract type: Fixed Term until 15th January 2025 in the first instance

Hours: Full-time

 

About the role

We are looking for an enthusiastic Clinical Data Manager to join the Surgical Intervention Trials Unit (SITU), working within a multi-disciplinary environment in order to develop, implement and run clinical trial data management activities. The Clinical Data Manager will join the established Data Management Team within SITU, supporting the activities of the clinical trials and working closely with trial managers and trial co-ordinators. This post will involve setting up and managing efficient data management and administrative systems for the SITU trials, being responsible for the development of case report forms (CRFs), completing database build-related procedures, report creation and liaising with programmers accordingly. You will also be required to deliver database and randomisation system training to SITU and site staff. You will be responsible for ensuring standard operating procedures (SOPs) for data processing are adhered to.  

 

About you 

The successful candidate will hold a first degree in IT or life sciences or equivalent experience. It is essential that you have a demonstrable understanding of the role of data management in contributing to the conduct of high-quality clinical trials and compliance with regulatory standards such as ICH-GCP and UK Clinical Trials Regulations. You will have experience of working within a clinical trial setting and using common data management systems. You will have excellent communication and interpersonal skills with the ability to self-motivate and work well within a team environment.  

 

This is a full-time post is available immediately and is fixed-term until 15th January 2025 in the first instance. We would be willing to consider applications for part-time hours.   

 

Application Process

Applications for this vacancy are to be made online and as part of the application process you are required to upload your CV and a covering letter.  Please quote reference NDSA928 on all correspondence. 

 

Only applications received before noon on Monday 20th May 2024 can be considered.

 

Interviews will be held in the morning of Thursday 30th May 2024.

 

Committed to equality and valuing diversity
"""^^ . . . _:N58ce392bdba948ecada830eb37046ebf . . "Botnar Research Centre" . """**Contract type: Fixed Term until 15th January 2025 in the first instance** **Hours: Full-time** **About the role** We are looking for an enthusiastic Clinical Data Manager to join the Surgical Intervention Trials Unit (SITU), working within a multi-disciplinary environment in order to develop, implement and run clinical trial data management activities. The Clinical Data Manager will join the established Data Management Team within SITU, supporting the activities of the clinical trials and working closely with trial managers and trial co-ordinators. This post will involve setting up and managing efficient data management and administrative systems for the SITU trials, being responsible for the development of case report forms (CRFs), completing database build-related procedures, report creation and liaising with programmers accordingly. You will also be required to deliver database and randomisation system training to SITU and site staff. You will be responsible for ensuring standard operating procedures (SOPs) for data processing are adhered to. **About you** The successful candidate will hold a first degree in IT or life sciences or equivalent experience. It is essential that you have a demonstrable understanding of the role of data management in contributing to the conduct of high-quality clinical trials and compliance with regulatory standards such as ICH-GCP and UK Clinical Trials Regulations. You will have experience of working within a clinical trial setting and using common data management systems. You will have excellent communication and interpersonal skills with the ability to self-motivate and work well within a team environment. This is a full-time post is available immediately and is fixed-term until 15th January 2025 in the first instance. We would be willing to consider applications for part-time hours. **Application Process** Applications for this vacancy are to be made online and as part of the application process you are required to upload your CV and a covering letter. Please quote reference NDSA928 on all correspondence. Only applications received before noon on Monday 20th May 2024 can be considered. Interviews will be held in the morning of Thursday 30th May 2024. **Committed to equality and valuing diversity** """ . . "University of Oxford" . "comment" . . . . . _:N9541117b1a1e4ae4adcbca126c521337 "Oxford" . "sous-Organization de"@fr . . "tiene sede principal en"@es . . "Voice"@en . . "Title"@en . . _:N06ea44737efa4856ae90d582f6fb0e1d . . . "OUCS code" . . . _:N58ce392bdba948ecada830eb37046ebf . "Trial Coordinator – DISCUS and Trans-EndoNET" . . . "NDSA926 Postdoctoral Researcher in Cellular Therapeutics JD.doc" . . . . . . . . . "2B06"^^ . "in dataset" . . "has primary place" . . "has exact match"@en . . . . . . . . . . "Nuffield Department of Surgical Sciences" . . """**Contract type: Fixed term until 02 January 2025** **Hours: Full-time** **About the role** We are looking for an enthusiastic Clinical Trial Coordinator to join the Surgical Intervention Trials Unit (SITU), working within a multi-disciplinary environment in order to develop, implement and run clinical trial activities. You will be based at the Botnar Research Centre in Headington, Oxford but you will be able to agree a pattern of regular remote working with your line manager. The Clinical Trial Coordinator will join the established Trial Management Team within SITU, supporting the activities of the clinical trials and working closely with trial managers and data managers. This post will involve ensuring the effective conduct of the study in accordance with the trial protocol and regulatory and institutional procedures where appropriate. You will manage the trial email account, maintain trial files and will help manage activities of the participating clinical centres, which may include conducting site visits and addressing training needs where appropriate. **About you** The successful candidate will be educated to A level or equivalent in English, Maths and a Science related subject. You will have previous experience in clinical research and working knowledge of the relevant ethical, legislative and research governance requirements relevant to clinical trials as well as familiarity with medical terminology. Excellent communication skills are essential as well as good organisational and problem-solving skills. You will have excellent communication and interpersonal skills with the ability to self-motivate and work well within a team environment. A willingness to travel to trial sites and meetings nationally is essential. This full-time post is available immediately and is fixed-term until 2nd January 2025 in the first instance. We would be willing to consider applications for part-time hours. **Application Process** If you would like to discuss this role, please contact the NDS SITU Operational Lead, Amy Taylor at op.lead@nds.ox.ac.uk Applications for this vacancy are to be made online. You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application. Please quote reference NDSA930 on all correspondence. Only applications received before noon Tuesday 21st May 2024 can be considered. Interviews will be held on Thursday 30th May 2024. **Committed to equality and valuing diversity** """ .