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Postdoctoral Scientist – Protein Biochemistry & Structural Biology

Applications for this vacancy closed on 9 October 2023 at 12:00PM
**PREVIOUS APPLICANTS NEED NOT APPLY **





We are seeking a highly motivated Postdoctoral Scientist to join the Target
Discovery Institute, at the Nuffield Department of Medicine. You will join us
to work on an exciting research project with focus on the structural and
functional exploration of proteins involved in ubiquitin and RNA metabolism
(e.g. E3 ligases, DUBs, deaminases), and the design, identification and
characterization of first-in-class chemical ligands.





The role will involve establishing efficient expression and purification
systems for target proteins. You will develop biochemical assays and study the
interaction between proteins and first-in-class small molecule ligands to
establish the SAR (structure activity relationship) to inform medicinal
chemistry. You will supervise junior and technical staff and coordinate the
project with other internal and external partners. This will include progress
reports and publishing high quality manuscripts in peer-reviewed journals.
Candidates are expected to represent the group at international scientific
meetings.





It is essential that you hold a PhD (or near completion) in protein
biochemistry and structural biology with an excellent academic track record,
including at least one first author publication in an expert journal. You will
have experience in protein crystallization and optimization of protein
crystals, and extensive experience in cloning and recombinant protein
purification using bacterial, insect cell or mammalian host systems. It is
essential that you are able to work independently and as part of a team and be
able to collaborate with colleagues on a range of diverse projects.





Applications for this vacancy are to be made online and you will be required
to upload a supporting statement and CV as part of your online application.
Your supporting statement must explain how you meet each of the selection
criteria for the post using examples of your skills and experience. Full-text
PDF copies of published articles are not required to be included in the
application, DOIs or PubMed links are sufficient.





This position is offered full time on a fixed-term contract until 1 April 2025
in the first instance and is funded by EU-IMI.





Only applications received before 12 midday on 9 October 2023 will be
considered. Please quote **163652** on all correspondence.

dc:spatial
Target Discovery Institute, NDM Research Building, Roosevelt Drive, Headington, Oxford, OX3 7FZ
Subject
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oo:formalOrganization
oo:organizationPart
vacancy:applicationClosingDate
2023-10-09 12:00:00+01:00
vacancy:applicationOpeningDate
2023-09-11 09:00:00+01:00
vacancy:furtherParticulars
vacancy:internalApplicationsOnly
False
vacancy:salary
type
comment

PREVIOUS APPLICANTS NEED NOT APPLY 

 

We are seeking a highly motivated Postdoctoral Scientist to join the Target Discovery Institute, at the Nuffield Department of Medicine. You will join us to work on an exciting research project with focus on the structural and functional exploration of proteins involved in ubiquitin and RNA metabolism (e.g. E3 ligases, DUBs, deaminases), and the design, identification and characterization of first-in-class chemical ligands.

 

The role will involve establishing efficient expression and purification systems for target proteins. You will develop biochemical assays and study the interaction between proteins and first-in-class small molecule ligands to establish ...
**PREVIOUS APPLICANTS NEED NOT APPLY **





We are seeking a highly motivated Postdoctoral Scientist to join the Target
Discovery Institute, at the Nuffield Department of Medicine. You will join us
to work on an exciting research project with focus on the structural and
functional exploration of proteins involved in ubiquitin and RNA metabolism
(e.g. E3 ligases, DUBs, deaminases), and the design, identification and
characterization of first-in-class chemical ligands.





The role will involve establishing efficient expression and purification
systems for target proteins. You will develop biochemical assays and study the
interaction between proteins and first-in-class small molecule ligands to
establish the ...
label
Postdoctoral Scientist – Protein Biochemistry & Structural Biology
notation
163652
based near
page