Postdoctoral Research Associate
Applications for this vacancy closed on 19 April 2024 at 12:00PM
**About the role**
This is a 6-month postdoctoral post that will continue the development of
metabolic engineering strategies to accumulation bioplastics in plants at
commercially relevant yields. The project is targeting the accumulation of
polyhydroxybutyrate (PHB) in plants, using _Marchantia polymorpha_ and tobacco
as testbeds to prototype and optimize the engineering interventions. A
particular focus will be on controlling competition for the substrate of the
pathway, acetyl CoA, which is also the substrate for important endogenous
metabolic pathways including fatty acid biosynthesis and isoprenoid
biosynthesis. Approaches using inducible control of transgene expression and
localization of enzymes to biomolecular condensates formed using synthetic
scaffolds will be explored.
**About you**
We seek an enthusiastic new colleague who holds a relevant PhD/DPhil or is
near to completion, together with relevant experience. It is essential that
you have previous experience and expertise of plant metabolic engineering, and
optogenetic gene regulation in plants and the use of synthetic biomolecular
condensates in plants.
**How to apply**
Applications for this vacancy are to be made online via our e-recruitment
system, and should include the application letter, a CV, a list addressing the
job criteria, and names of two academic references. Where Covid-19 has
resulted in substantial disruption to your work or research outputs, please
explain this by providing an additional paragraph in your supporting
statement.
The University of Oxford is committed to equality and valuing diversity. All
applicants will be judged on merit, according to the selection criteria.
This post is a 6-month fixed term, full time position and is available from 01
May 2024.
The closing date for applications is 12.00 noon on Friday 19 April 2024
For further inquiries, please contact Prof Lee Sweetlove:
lee.sweetlove@biology.ox.ac.uk
This is a 6-month postdoctoral post that will continue the development of
metabolic engineering strategies to accumulation bioplastics in plants at
commercially relevant yields. The project is targeting the accumulation of
polyhydroxybutyrate (PHB) in plants, using _Marchantia polymorpha_ and tobacco
as testbeds to prototype and optimize the engineering interventions. A
particular focus will be on controlling competition for the substrate of the
pathway, acetyl CoA, which is also the substrate for important endogenous
metabolic pathways including fatty acid biosynthesis and isoprenoid
biosynthesis. Approaches using inducible control of transgene expression and
localization of enzymes to biomolecular condensates formed using synthetic
scaffolds will be explored.
**About you**
We seek an enthusiastic new colleague who holds a relevant PhD/DPhil or is
near to completion, together with relevant experience. It is essential that
you have previous experience and expertise of plant metabolic engineering, and
optogenetic gene regulation in plants and the use of synthetic biomolecular
condensates in plants.
**How to apply**
Applications for this vacancy are to be made online via our e-recruitment
system, and should include the application letter, a CV, a list addressing the
job criteria, and names of two academic references. Where Covid-19 has
resulted in substantial disruption to your work or research outputs, please
explain this by providing an additional paragraph in your supporting
statement.
The University of Oxford is committed to equality and valuing diversity. All
applicants will be judged on merit, according to the selection criteria.
This post is a 6-month fixed term, full time position and is available from 01
May 2024.
The closing date for applications is 12.00 noon on Friday 19 April 2024
For further inquiries, please contact Prof Lee Sweetlove:
lee.sweetlove@biology.ox.ac.uk
| dc:spatial |
Department of Biology, 11a Mansfield Road, Oxford OX1 3SZ
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| Subject | |
| oo:contact | |
| oo:organizationPart | |
| vacancy:applicationClosingDate |
2024-04-19 12:00:00+01:00
|
| vacancy:applicationOpeningDate |
2024-03-22 09:00:00+00:00
|
| vacancy:furtherParticulars | |
| vacancy:internalApplicationsOnly |
False
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| vacancy:salary | |
| type | |
| comment |
About the role This is a 6-month postdoctoral post that will continue the development of metabolic engineering strategies to accumulation bioplastics in plants at commercially relevant yields. The project is targeting the accumulation of polyhydroxybutyrate (PHB) in plants, using Marchantia polymorpha and tobacco as testbeds to prototype and optimize the engineering interventions. A particular focus will be on controlling competition for the substrate of the pathway, acetyl CoA, which is also the substrate for important endogenous metabolic pathways including fatty acid biosynthesis and isoprenoid biosynthesis. Approaches using inducible control of transgene expression and localization of enzymes to biomolecular condensates ... **About the role**
This is a 6-month postdoctoral post that will continue the development of metabolic engineering strategies to accumulation bioplastics in plants at commercially relevant yields. The project is targeting the accumulation of polyhydroxybutyrate (PHB) in plants, using _Marchantia polymorpha_ and tobacco as testbeds to prototype and optimize the engineering interventions. A particular focus will be on controlling competition for the substrate of the pathway, acetyl CoA, which is also the substrate for important endogenous metabolic pathways including fatty acid biosynthesis and isoprenoid biosynthesis. Approaches using inducible control of transgene expression and localization of enzymes to biomolecular condensates formed ... |
| label |
Postdoctoral Research Associate
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| notation |
171652
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| based near | |
| page |