Postdoctoral Research Assistant in R-loop biology

We are seeking to appoint a well-trained, enthusiastic and self-motivated
scientist to join the laboratory of Associate Professor Natalia Gromak at the
Sir William Dunn School of Pathology, University of Oxford. The main interest
of the laboratory is to investigate the mechanisms underlying the function of
non-canonical RNA/DNA structures (R-loops) in health and diseases.





The post-holder will be responsible for managing their own academic research.
You will establish and optimise protocols, design and accurately execute
experiments and contribute conceptually to the overall research programme. The
post-holder will contribute directly to scientific discussions with the Group
Leader and other members of the group and collaborators on the project. You
will also supervise and train junior staff in molecular biology/biochemistry.





The post holder should hold, or be close to completion of, a PhD/DPhil in
biochemistry, molecular/cell biology or genetics and have a good understanding
of the principals of gene expression in higher eukaryotes. The research
project will involve a wide range of molecular biology and biochemical
techniques, including RNA work, protein purification, mammalian cell culture,
next generation sequencing genome-wide analyses (ChIP) and mass spectrometry.
Previous expertise in either molecular mechanisms of transcription, RNA
processing, DNA damage or R-loop biology would be essential for this job. You
should also have strong publication record, good organizational and
communication skills, and being able to work as part of a team. Candidates
with experience in genomic analyses, proteomic approaches, imaging analysis,
iPS differentiation and bioinformatics would be especially welcome.





Further information about the group and project can be found on:
https://www.path.ox.ac.uk/content/natalia-gromak.





The post available as a fixed-term contract for 2 years in the first instance.
If you are interested in this position, and have the skills and experience we
are looking for, please apply below. You will be required to upload a CV and
supporting statement as part of your online application.





The closing date for applications is midday on Monday 22 July 2024. Interviews
will be held w/c 29th July 2024 or as soon as possible thereafter.