Research Assistant in R-loop biology

<div xmlns="http://www.w3.org/1999/xhtml"> <p></p><div>We are seeking to appoint an enthusiastic and self-motivated Research Assistant to join the laboratory of Associate Professor Natalia Gromak at the Sir William Dunn School of Pathology, University of Oxford. The main interest of the laboratory is to investigate the mechanisms underlying the function of non-canonical nucleic acid structures (R-loops) in health and diseases.</div><br> <div>&#160;</div><br> <div>The post-holder will manage a research project and contribute to the overall research programme and lab management. The research project will involve a wide range of molecular biology and biochemical techniques, including RNA work, mammalian cell culture, next generation sequencing genome-wide analyses (ChIP) and mass spectrometry.</div><br> <div>&#160;</div><br> <div>The post holder should hold, or be close to completion of, a BSc in biochemistry, molecular/cell biology or genetics and have a good understanding of the principals of gene expression in higher eukaryotes. Previous laboratory experience, good organisational and communication skills and the ability to work as part of a team are essential. Expertise in molecular mechanisms of transcription, RNA processing, DNA damage or R-loop biology are desirable. Candidates with experience in genomic analyses, proteomic approaches, imaging analysis, iPS differentiation and bioinformatics would be especially welcome. Training will be available in all aspects of the work, especially in the less standard protocols, although it is expected that applicants will be familiar with some of the necessary techniques.</div><br> <div>&#160;</div><br> <div>Further information about the group and project can be found on: <a rel="nofollow" href="https://www.path.ox.ac.uk/content/natalia-gromak">https://www.path.ox.ac.uk/content/natalia-gromak</a>.</div><br> <div>&#160;</div><br> <div>The post available as a fixed-term contract for 2 years in the first instance. If you are interested in this position, and have the skills and experience we are looking for, please apply below. You will be required to upload a CV and supporting statement as part of your online application.</div><br> <div>&#160;</div><br> <div>The closing date for applications is midday on 12 June 2024. Interviews will be held as soon as possible thereafter.</div> </div>