Postdoctoral Research Assistant in Cardiovascular Medicine

We are seeking a highly motivated Postdoctoral Research Assistant with
expertise and interest in Biochemistry to join the Reader and Tzima research
groups at the Centre for Human Genetics in Oxford. You will closely
collaborate with other laboratory members involved in more cell biological
approaches, thereby facilitating an integrative research environment.





The overarching goal of the project is to gain an understanding of fundamental
mechanisms of protein synthesis from both a biochemical and biophysical
perspective. The groups have been investigating the interaction of two ancient
cellular machineries, i.e. the protein translation and cytoskeletal
machineries and this project will investigate how these cross-talk. We use a
multi-disciplinary approach that includes expertise and collaborations in
enzymology, biochemistry, structural biology, and cell biology, and use a
combination of _in vitro_ and _ex cellulo_ approaches. The group has access to
a range of state-of-the-art facilities and technologies within the Centre of
Human Genetics, and more broadly as part of the University of Oxford.





You are required to hold a PhD/DPhil in a relevant discipline and will carry
out independent research exploring fundamental mechanisms of key cellular
functions from both a biophysical and biochemical perspective. You will also
have proven experience in recombinant protein purification from both bacterial
and eukaryotic protein expression systems, a familiarity with basic
enzymology, and experience in the characterization of individual proteins
and/or protein-protein interactions. Previous experience/familiarity with _in
vitro_ RNA preparative techniques and assays would be desirable.



This is a full time appointment on a fixed term contract for 1 year (with the
possibility of extending for a further 2 years) and you will be based at the
Centre for Human Genetics, Old Road Campus, Roosevelt Drive, Oxford, OX3 7BN.





Applications for this vacancy are to be made online; you will be required to
upload a CV and supporting statement which explains how you meet the selection
criteria for the post.





Only applications received before 12.00 midday on **16th September 2024** can
be considered. Interviews are scheduled to place the week of 30th September
2024.





The University is an Equal Opportunity Employer