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All vacancies within Department of Zoology

There are currently 1 vacancies within Department of Zoology:

Title Closes Salary
Postdoctoral Research Assistant in Evolutionary Dynamics of Antimicrobial Peptide Resistance July 12, 2019, noon Grade 7: £32,236 - £39,609 with a discretionary range to £43,267 p.a.

Postdoctoral Research Assistant in Evolutionary Dynamics of Antimicrobial Peptide Resistance

Closes: July 12, 2019, noon; salary: Grade 7: £32,236 - £39,609 with a discretionary range to £43,267 p.a.

<div> <p></p><p>A postdoctoral position is available in the MacLean lab at the University of Oxford, Department of Zoology to experimentally study the dynamics of mobile antimicrobial peptide resistance in pathogenic bacteria. The goal of these experiments will be to understand how antibiotic use and trade-offs influence the spread of antimicrobial peptide resistance in the key pathogens E coli and P aeruginosa. Using experimental evolution, the postholder will challenge populations of pathogenic bacteria to evolve resistance to a wide array of human, animal, and synthetic antimicrobial peptides under controlled conditions. The mechanisms of resistance evolution and associated trade-offs will then be investigated using a combination of high-throughput resistance assays combined next-generation sequencing and chemogenomic profiling of evolved clones.</p><br> <p>This post is ideally suited to ambitious researchers who have experience in the following areas: experimental evolution, antimicrobial peptide resistance, and chemogenomic profilling. The postholder will work as part of a Wellcome trust funded team that brings together genomics, experimental evolution, and mathematical modelling, and the postholder will be given the opportunity to contribute to the development and direction of this project. The successful candidate will hold a doctoral degree (or be near to completion) in a relevant subject area.</p><br> <p>Enquiries can be sent to: <a rel="nofollow" href="mailto:craig.maclean@zoo.ox.ac.uk"> craig.maclean@zoo.ox.ac.uk</a>.</p><br> <p>The closing date for applications is 12.00 noon on 12 July 2019.</p> </div>