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All vacancies within Radcliffe Department of Medicine
There are currently 4 vacancies within Radcliffe Department of Medicine:
| Title | Closes | Salary |
|---|---|---|
| Receptionist | June 30, 2025, noon | Standard Grade 3: £26,948 - £27,838 per annum pro rata |
| Post-Doctoral Research Assistant | July 8, 2025, noon | Research Grade 7: £38,674 - £46,913 |
| Clinical Research Nurse | July 10, 2025, noon | Standard Grade 5: £31,459 - £36,616 per annum |
| Research Assistant in T cell Immunology / Immunotherapeutics | July 15, 2025, noon | Grade 6: £34,982 - £40,855 per annum |
Receptionist
Closes: June 30, 2025, noon; salary: Standard Grade 3: £26,948 - £27,838 per annum pro rata
<div> <p></p><div>We are looking for an enthusiastic and motivated Receptionist to join the OCMR team. This position serves as the first point of contact for patients visiting the MRI Cardiac clinic, as well as for visitors to the OCMR research facility.</div><br> <div> </div><br> <div>The successful candidate will be expected to provide a friendly and professional service to clinical patients, visitors, and contractors while ensuring that safety procedures are followed at all times. Confidence and a positive attitude are essential for this role. Proficiency in Microsoft Office programs is required.</div><br> <div> </div><br> <div>Candidates should have an education to A-Level standard or equivalent. They must possess the ability to communicate effectively and professionally, both in person and in writing. Experience with NHS/OUH database systems (such as EPR) and familiarity with the University and OUH/NHS environment are desirable.</div><br> <div> </div><br> <div>This is a part-time position to cover the OCMR reception on weekday afternoons from 12:45 PM to 5:45 PM. You will be based at the Oxford Centre for Clinical Magnetic Resonance Research (OCMR), Level 0, John Radcliffe Hospital, Oxford, OX3 9DU. </div><br> <div> </div><br> <div><strong>Application Process</strong></div><br> <div> </div><br> <div>Applications for this vacancy are to be made online. You will be required to upload a covering letter with a supporting statement, CV and the details of two referees as part of your online application. In your supporting statement, please explain why you would like to do this role and how you meet the selection criteria in the job description. </div><br> <div> </div><br> <div>Only applications received by midday on Monday, 30th June 2025 can be considered.</div><br> <div> </div><br> <div>Interviews are scheduled to take place on Thursday, 19th July 2025, in-person at the OCMR</div><br> <div> </div><br> <div>If you would like further information about the role, please contact: OCMR Operations Manager - Marcin Grzegorczyk marcin.grzegorczyk@cardiov.ox.ac.uk</div> </div>Post-Doctoral Research Assistant
Closes: July 8, 2025, noon; salary: Research Grade 7: £38,674 - £46,913
<div> <p></p><div>The laboratory of Prof. Simon Davis and Dr. Mafalda Santos at the MRC Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, is seeking a talented and motivated Postdoctoral Research Associate to join an MRC-funded project investigating how immune checkpoint receptors regulate T-cell activation and function.</div><br> <div> </div><br> <div><strong>Project Overview</strong></div><br> <div> </div><br> <div>This project focuses on understanding the molecular mechanisms by which co-inhibitory receptors, including PD-1, BTLA, TIGIT, and CD200R, regulate T cell function in autoimmune settings. Despite sharing common downstream signalling components such as SHP1 and SHP2 phosphatases, these receptors exhibit strikingly different signalling capacities in disease settings. While these receptors are well known for their roles in cancer and infection, their involvement in preventing immune-mediated pathology in autoimmunity remains poorly understood.</div><br> <div> </div><br> <div>Using genetic and antibody-based targeting, we aim to dissect how these pathways modulate T-cell signalling, activation, and effector functions in preclinical models of autoimmunity. This research is part of a broader effort to define how inhibitory receptors tune T-cell responses in health and disease, ultimately informing the development of more precise immunotherapies.</div><br> <div> </div><br> <div>The successful candidate will:</div><br> <div>•         Design and carry out in vivo experiments in preclinical mouse models of autoimmunity</div><br> <div>•         Perform detailed T-cell phenotyping and functional assays</div><br> <div>•         Conduct mechanistic studies using molecular and cellular immunology techniques</div><br> <div>•         Contribute to data analysis, presentation, and publication of research findings</div><br> <div>•         Collaborate closely with internal and external researchers, including opportunities for co-supervision of students</div><br> <div> </div><br> <div><strong>Lab Environment</strong></div><br> <div> </div><br> <div>The T-cell Biology Group is part of the MRC WIMM, a leading biomedical research institute embedded within the Radcliffe Department of Medicine. We are situated in a highly interdisciplinary environment with outstanding facilities for mouse work, flow cytometry, genomics, and molecular biology. We maintain close collaborations with immunologists, structural biologists, and clinicians.</div><br> <div> </div><br> <div><strong>Essential Qualifications and Skills</strong></div><br> <div> </div><br> <div>We are seeking a creative immunologist with a strong interest in T cell biology and immune regulation. The ideal candidate will have:</div><br> <div>•         A PhD (or be close to completion) in immunology or a related biomedical field</div><br> <div>•         Demonstrable expertise in in vivo mouse models of immune function (e.g. infection, tumour, autoimmunity, or tolerance)</div><br> <div>•         Strong experience with primary T cell isolation, stimulation, and functional assays</div><br> <div>•         Proficiency in multi-colour flow cytometry and data analysis</div><br> <div>•         A good understanding of T cell receptor signalling and/or immune checkpoint pathways</div><br> <div>•         Experience with molecular techniques such as CRISPR/Cas9 editing, retroviral transduction, or transcriptomics</div><br> <div> </div><br> <div><strong>Further Information</strong></div><br> <div> </div><br> <div>This is a full-time post based at the WIMM, University of Oxford and fixed-term for 1 year in the first instance. </div><br> <div> </div><br> <div>Informal enquiries are welcome and can be directed to Prof. Simon Davis at simon.davis@imm.ox.ac.uk and Dr. Mafalda Santos at mafalda.santos@rdm.ox.ac.uk.</div><br> <div> </div><br> <div>Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application.</div><br> <div> </div><br> <div>Only applications received before 12:00 midday on <em>08 July 2025</em> will be considered.</div> </div>Clinical Research Nurse
Closes: July 10, 2025, noon; salary: Standard Grade 5: £31,459 - £36,616 per annum
<div> <p></p><div>We are seeking a highly motivated Clinical Research Nurse or Clinical Research Practitioner (CRP) to join our friendly and approachable Research Nurse and Support Team (RN&ST) within the internationally acclaimed Division of Cardiovascular Medicine, renowned for its excellence in clinical research.</div><br> <div> </div><br> <div>The post holder will report to the CVM lead nurse and provide support for CVM research studies across its three clinical research facilities [OCMR, CCRF, AMIIC] as well as the clinical cardiac facilities of Oxford University Hospital Trust Heart Centre, where they will hold an honorary contract.</div><br> <div> </div><br> <div>They will work alongside a multi-disciplinary team of nurses, CRPs, principle investigators, radiographers, cardiac physiologists and clinical governance leads. Strong teamwork and a pro-active ‘can-do’ attitude are essential for the post, along with excellent communication skills.</div><br> <div> </div><br> <div>The post holder will be responsible for supporting the identification, pre-screening, recruitment, and consent of patients into all types of cardiac research studies from observational to commercial clinical trials. The role will involve carrying out key practical elements of research delivery, including accurate data collection, blood sampling and processing. They will support study co-ordinators and principle investigators, contributing to the set-up and co-ordination of new studies and take responsibility for a small portfolio of non-complex observational studies.</div><br> <div> </div><br> <div>The successful candidate will be required to be a registered nurse on part 1 (adult) of the NMC register (please state PIN) or Clinical Research Practitioner registered with the AHCS (please state AHCS registration date and re-accreditation) and have a degree in a relevant subject e.g. Nursing/Biological Sciences. Experience of working in research in a clinical setting is desirable.</div><br> <div> </div><br> <div>This is a full-time appointment on a fixed term contract for 3 years (may be extended depending on funding). The post holder will join the RN&ST based at the Oxford Centre for Clinical Magnetic Resonance Research (OCMR), John Radcliffe Hospital, Oxford OX3 9DU.</div><br> <div> </div><br> <div>Applications for this vacancy are to be made online via the University website; you will be required to upload a CV and supporting statement which explains how you meet the selection criteria for the post.</div><br> <div> </div><br> <div>Only applications received before midday on July 10th 2025 can be considered.</div><br> <div> </div><br> <div>Interviews are scheduled to take place September 1st 2025.</div> </div>Research Assistant in T cell Immunology / Immunotherapeutics
Closes: July 15, 2025, noon; salary: Grade 6: £34,982 - £40,855 per annum
<div> <p></p><div>This is an exciting and unique opportunity for a talented, curious scientist who wants to make new scientific discoveries in T cell immunology and immunotherapeutics. You will work in the  <a rel="nofollow" href="https://www.rdm.ox.ac.uk/about/our-divisions/nuffield-division-of-clinical-laboratory-sciences/nuffield-division-of-clinical-laboratory-sciences-research/normal-and-malignant-haematopoiesis-lab">Vyas Laboratory</a> on discovering new peptide-HLA-II (pHLA-II) antigens and their cognate T cell receptors (TCRs), interrogating their function, molecular and biophysical features and conduct proof of concept work to establish their utility as immunotherapeutics.</div><br> <div> </div><br> <div>You will be part of a multi-disciplinary team that includes immunologists with molecular, cellular, biochemical and structural expertise. You will work with patient samples and dissect alloreactive immune responses, repurposing them to make novel TCR-T cell and soluble bispecific T cell engager therapeutics.</div><br> <div> </div><br> <div>You will have an undergraduate degree in a relevant biological science, together with relevant laboratory and computational experience (flow cytometry, cell culture, molecular sub-cloning and analysis of next generation sequence data). Experience in coding and using computational pipelines with specialist knowledge in T cell immunology and immunology of cancer and cancer immunotherapeutics will be essential.</div><br> <div> </div><br> <div>The role could suit an applicant wanting to go onto do a PhD or wanting to explore working in the Vyas Laboratory on a longer term basis.</div><br> <div> </div><br> <div>The post is available fixed-term for 12 months, funded by  <a rel="nofollow" href="https://yellowstonebio.com/">Yellowstone Bioscience</a>.</div><br> <div> </div><br> <div>Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.</div><br> <div> </div><br> <div>The closing date for this position is <strong>12:00 noon on Monday 15 July 2025</strong>.  Interviews will be held w/c 28 July 2025.</div><br> <div> </div> </div>