All vacancies within Radcliffe Department of Medicine

There are currently 5 vacancies within Radcliffe Department of Medicine:

Title	Closes	Salary
Postdoctoral Research Assistant in Intracellular Antibodies in Leukaemia Therapy	Jan. 9, 2019, noon	Grade 7: £32,236 - £39,609 p.a.
Tissue Bank Technician	Jan. 9, 2019, noon	Grade 6: £28,660 - £34,189 with a discretionary range to £37,345 p.a.
Postdoctoral Scientist in Leukaemia Therapeutics	Jan. 11, 2019, noon	Grade 7: £32,236 - £39,609 p.a.
Clinical Research Assistant	Jan. 16, 2019, noon	Grade 6: £28,660 - £34,189 p.a
Clinical Lecturer in Microbiology and Infectious Diseases	Feb. 6, 2019, noon	Grade A63 or A67: £32,478 - £57,444 p.a. dependent on qualifications and experience, in line with current pay protection and transitional arrangements in the NHS

Postdoctoral Research Assistant in Intracellular Antibodies in Leukaemia Therapy

Closes: Jan. 9, 2019, noon; salary: Grade 7: £32,236 - £39,609 p.a.

<div> Applications are invited for a Postdoctoral Research Assistant position to be part of the Intracellular Antibodies in Leukaemia Therapy programme, led by Professor Terry Rabbitts, to develop macromolecules and drugs targeting protein interactions in cancer, in particular acute leukaemia. The post will focus on the implementation of intracellular antibody fragments and small molecules, derived from antibody fragments, to interfere with protein function in leukaemia. In particular, development of techniques for intracellular antibody development and small molecule inhibitors of LMO2 and KRAS in acute leukaemia. Candidates must have a PhD in a biological subject and experience in molecular biology, tissue culture and immunological methods. Experience with yeast culture and phage display and biophysical methods of protein analysis are also essential. Experience with Next Generation Deep Sequencing, recombinant viruses and crystallography would be an advantage. The post is available fixed-term until 31 December 2019, funded by Bloodwise. Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application The closing date for this position is 12.00 midday on Wednesday 9 January 2019. </div>

Tissue Bank Technician

Closes: Jan. 9, 2019, noon; salary: Grade 6: £28,660 - £34,189 with a discretionary range to £37,345 p.a.

<div> An exciting new opportunity has arisen for a Tissue Bank Technician. Oxford Haematology is one of the largest academic haematology units in Europe and we are expanding the tissue banking programme for the blood cancers that we treat, so that we can use these precious resources donated by our patients, for research into how better to understand and treat these diseases. You will be responsible for biobanking peripheral blood, bone marrow and lymph node samples from patients with myeloma and lymphoma and for the analysis of these samples. As the study of these samples is the cornerstone of much of the research we do, you will play a critical role in the team. Duties will include the collection, processing and cryo-preservation of bone marrow, peripheral blood samples and tissue biopsy samples (such as lymph nodes) from patients. This entails preparing mononuclear cell preparations, selecting specific cell populations and performing FACS analysis to immunophenotype samples and to check the purity of cell population enrichment before cryopreservation. Further processing such as DNA and RNA extraction, and banking of fresh lymph node samples may also be required. The post is available fixed-term for 24 months, funded by Bristol Myers Squibb and Oxford University Hospitals Charitable Funds. You will hold a degree in a relevant biomedical or scientific discipline, with a demonstrable understanding of cell biology. Previous experience of working as part of a team in a laboratory environment with the ability to problem-solve and to plan and manage work schedules to deliver agreed targets is essential. You will have good attention to detail, communication, manual dexterity and record keeping skills. Previous experience of molecular biology research and FACS immunophenotyping are desirable. Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application. The closing date for this position is 12.00 noon on Wednesday 9 January 2019. Interviews will be held in January 2019. </div>

Postdoctoral Scientist in Leukaemia Therapeutics

Closes: Jan. 11, 2019, noon; salary: Grade 7: £32,236 - £39,609 p.a.

<div> Applications are invited for a Postdoctoral Scientist to join a highly motivated research team working under the supervision of Professor Sten Eirik Jacobsen, in the Haematopoietic Stem Cell Biology Laboratory, at the MRC Weatherall Institute of Molecular Medicine (www.imm.ox.ac.uk/home). The position, dedicated towards the development of novel small molecule therapeutics targeting the MDS stem cells recently identified by the Jacobsen lab (Tehranchi R et al, N Engl J Med 2010; Woll et al, Cancer Cell 2014), will be funded by OxStem Oncology, the first stand-alone company to be formed under the OxStem umbrella (www.oxstem.com). OxStem is a revolutionary spin-out company from the University of Oxford, founded by Professor Steve Davies, Professor Dame Kay Davies and Professor Angela Russell, which raised a record-breaking £16.9M in its initial funding round. OxStem Oncology aims to identify new classes of drug candidates that will differentiate 'cancer stem-like cells' (CSLCs) to more benign states that will improve clinical outcomes and overcome resistance/relapse. The team will focus initially on Acute Myeloid Leukaemia and Myelodysplastic Syndromes with a view to expanding to other conditions over time. This is an extraordinary opportunity to work with world leading researchers and contribute to the development of innovative new therapies for areas of significant unmet medical need. You will hold a PhD (or be close to completion) in a relevant area and have previous experience in experimental application of molecular and cellular biology techniques, to the study of normal and/or malignant haematopoiesis. You will be a self-motivated, enthusiastic self-starter who can work with minimum supervision with good organisational skills to plan experimental bench-work and meet required deadlines. Excellent communication skills and the ability to be innovative are essential. The post is fixed-term until 2 November 2019 in the first instance, with the possibility of further extension. Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application. The closing date for this position is 12.00 noon on Friday 11 January 2019. </div>

Clinical Research Assistant

Closes: Jan. 16, 2019, noon; salary: Grade 6: £28,660 - £34,189 p.a

<div> We are looking for an enthusiastic researcher (study nurse, radiographer, physiologist, or with other relevant background), to drive a clinical trial validating the ability of a new technology to track changes of inflammation in the human coronary arteries in response to treatments, using standard computed tomography angiography. The technology is called Fat Attenuation Indexing (FAI) and had been recently found to predict heart attacks years in advance. As part of this team, you will recruit and screen new participants in order to establish their eligibility and safety to enter the study and to register/randomise participants into the study. As well as this you will Facilitate the informed consent process and provide ongoing information, education and support to participants. You will be a registered qualified Nurse, Radiographer, Physiologist or have a similar background and have excellent written and oral communication skills, evidenced by the ability to explain and interpret procedures clearly and sensitively. Experience with imaging and image analysis (CT and/or ultrasound) would be desirable. This full-time appointment is on a fixed-term for 3 years, and you will work under the supervision of Professor Charalambos Antoniades. The post is funded by Innovate UK and you will be based at the John Radcliffe Hospital, Oxford, OX3 9DU. Applications for this vacancy are to be made online; you will be required to upload a CV and supporting statement which explains how you meet the selection criteria for the post. Only applications received before 12.00 midday on 16 January 2019 can be considered. Interviews are scheduled to place on 30 January 2019. </div>

Clinical Lecturer in Microbiology and Infectious Diseases

Closes: Feb. 6, 2019, noon; salary: Grade A63 or A67: £32,478 - £57,444 p.a. dependent on qualifications and experience, in line with current pay protection and transitional arrangements in the NHS

<div> Applications are invited for the above post in the Nuffield Division of Clinical Laboratory Sciences, which offers full clinical training with additional training opportunities for developing a career in medical education or research. As well as making a substantial contribution to the clinical work of the department, the Clinical Lecturer will be responsible for the coordination and development of Microbiology teaching for year 4 medical students and will also engage in research, with 50% protected time for academic work. This is a fixed-term post (for 4 years or until CCT, whichever is sooner) which offers excellent opportunities to undertake high quality research and teaching within a clinically excellent environment, and to work towards gaining a CCT. Applicants should be medically qualified, ST3 and above, have full GMC registration and will have demonstrated ability and commitment to teaching and research, as well as outstanding skills in oral and written scientific and clinical communication. The post will be based in the Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, JR Hospital, OX3 9DU. Queries about the post should be addressed to Professor Alison Banham (<a rel="nofollow" href="mailto:alison.banham@ndcls.ox.ac.uk">alison.banham@ndcls.ox.ac.uk</a>), Dr Deborah Hay (<a rel="nofollow" href="mailto:deborah.hay@ndcls.ox.ac.uk">deborah.hay@ndcls.ox.ac.uk</a>) or Dr Bridget Atkins (<a rel="nofollow" href="mailto:Bridget.Atkins@ouh.nhs.uk">Bridget.Atkins@ouh.nhs.uk</a>). The closing date for this post is 12.00 noon on 6 February 2019. Interviews will be held on 20 March 2019. Applications are particularly welcome from women and black and minority ethnic candidates, who are under-represented in academic posts in Oxford. </div>