Postdoctoral Research Assistant in Cancer Immunology for Stimulus-Responsive Immune-modulation

<div xmlns="http://www.w3.org/1999/xhtml"> <p></p><div>An exciting opportunity for a translationally focused Postdoctoral Researcher in Cancer Immunology is now available. Reporting to Prof Constantin Coussios (OBE, FREng), the project uses novel stimuli responsive nanoparticles to modulate the tumour microenvironment and the candidate will form an integral part of translating this technology to the clinic. The post is supported by a benefactor donation to the University and is fixed-term for 24 months, with possibility of further extension subject to funding renewal.&#160;</div><br> <div>&#160;</div><br> <div>The overall aim of the project is to enable the development and clinical translation of a new generation of protein-based ultrasound-responsive particles specifically designed to illicit immune responses in tumours for enhanced cancer therapy. The specific role of the person appointed will be to design and perform testing both <em>in vitro</em> and <em>in vivo</em> to characterize and optimize the immune-modulatory response elicited by the combination of ultrasound and protein-based particles.</div><br> <div>&#160;</div><br> <div>You should possess a PhD in immunology, cancer biology, biochemistry or relevant discipline, with considerable post-qualification research experience. You also should have the ability to work in a multidisciplinary team of researchers with both physical and life sciences backgrounds engineers, biologists and clinicians, and have strong evidence of research achievement to date.&#160; Experience with a broad range of immunological techniques such as high dimensional flow cytometry, T cell in vitro functional assays, single cell/bulk RNA sequencing and spatial biological imaging is required. An active UK Home Office animal licence is also highly desirable. Additional experience with therapeutic ultrasound, cavitation monitoring, in vivo experimentation and ultrasound-responsive particles will also be viewed favourably. &#160;</div><br> <div>&#160;</div><br> <div>Informal enquiries may be addressed to Professor Constantin Coussios (constantin.coussios@eng.ox.ac.uk).</div><br> <div>&#160;</div><br> <div>For more information about working at the Department, see &#160;<a rel="nofollow" href="http://www.eng.ox.ac.uk/about/work-with-us/">www.eng.ox.ac.uk/about/work-with-us/</a></div><br> <div>&#160;</div><br> <div>Only applications received before midday <strong>30 August 2024</strong>&#160;can be considered. You will be required to upload a covering letter, a brief statement of research interests (describing how past experience and future plans fit with the advertised position), CV and the details of three referees as part of your online application.</div><br> <div>&#160;</div><br> <div>The Department holds an Athena Swan Bronze award, highlighting its commitment to promoting women in Science, Engineering and Technology.</div> </div>