Senior Research Associate in Cancer Immunology for Stimulus-Responsive Immune-modulation

We are seeking a full-time Senior Research Associate to join an
interdisciplinary research team developing new stimulus-responsive techniques
for ultrasound-mediated immune-modulation at the Institute of Biomedical
Engineering (Botnar Research Centre, Headington). The post is supported by a
benefactor donation to the University and is fixed-term for 12 months, with
the possibility of an extension up to 2 years.





The overall aim of the project is to enable the development and clinical
translation of a new generation of protein-based ultrasound-responsive
particles specifically designed to illicit immune responses in tumours for
enhanced cancer therapy. The specific role of the person appointed will be to
design and perform testing both _in vitro_ and _in vivo_ to characterize and
optimize the immune-modulatory response elicited by the combination of
ultrasound and protein-based particles.





You should possess a PhD in immunology, cancer biology, biochemistry or
relevant discipline, with considerable post-qualification research experience.
You also should have the ability to work in a multidisciplinary team of
researchers with both physical and life sciences backgrounds engineers,
biologists and clinicians, and have strong evidence of research achievement to
date.





Experience with a broad range of immunological techniques such as high
dimensional flow cytometry, T cell in vitro functional assays, single
cell/bulk RNA sequencing and spatial biological imaging is required.
Additional experience with therapeutic ultrasound, cavitation monitoring, in
vivo experimentation and ultrasound-responsive particles will also be viewed
favourably.





Informal enquiries may be addressed to Professor Constantin Coussios
(constantin.coussios@eng.ox.ac.uk).





For more information about working at the Department, see
www.eng.ox.ac.uk/about/work-with-us/





Only applications received before midday on **5 February 2024** can be
considered. You will be required to upload a covering letter, a brief
statement of research interests (describing how past experience and future
plans fit with the advertised position), CV and the details of three referees
as part of your online application.





The Department holds an Athena Swan Bronze award, highlighting its commitment
to promoting women in Science, Engineering and Technology.