Senior Research Associate in Cancer Immunology for Stimulus-Responsive Immune-modulation

<div xmlns="http://www.w3.org/1999/xhtml"> <p></p><div>We are seeking a full-time Senior Research Associate to join an interdisciplinary research team developing new stimulus-responsive techniques for ultrasound-mediated immune-modulation at the Institute of Biomedical Engineering (Botnar Research Centre, Headington).&#160; The post is supported by a benefactor donation to the University and is fixed-term for 12 months, with the possibility of an extension up to 2 years.</div><br> <div>&#160;</div><br> <div>The overall aim of the project is to enable the development and clinical translation of a new generation of protein-based ultrasound-responsive particles specifically designed to illicit immune responses in tumours for enhanced cancer therapy. The specific role of the person appointed will be to design and perform testing both <em>in vitro</em> and <em>in vivo</em> to characterize and optimize the immune-modulatory response elicited by the combination of ultrasound and protein-based particles.</div><br> <div>&#160;</div><br> <div>You should possess a PhD in immunology, cancer biology, biochemistry or relevant discipline,&#160;with considerable post-qualification research experience.&#160;&#160;You also should have the ability to work in a multidisciplinary team of researchers with both physical and life sciences backgrounds engineers, biologists and clinicians, and have strong evidence of research achievement to date.</div><br> <div>&#160;</div><br> <div>Experience with a broad range of immunological techniques such as high dimensional flow cytometry, T cell in vitro functional assays, single cell/bulk RNA sequencing and spatial biological imaging is required. Additional experience with therapeutic ultrasound, cavitation monitoring, in vivo experimentation and ultrasound-responsive particles will also be viewed favourably.</div><br> <div>&#160;</div><br> <div>Informal enquiries may be addressed to Professor Constantin Coussios (constantin.coussios@eng.ox.ac.uk).</div><br> <div>&#160;</div><br> <div>For more information about working at the Department, see &#160;<a rel="nofollow" href="http://www.eng.ox.ac.uk/about/work-with-us/">www.eng.ox.ac.uk/about/work-with-us/</a></div><br> <div>&#160;</div><br> <div>Only applications received before midday on&#160;<strong>5 February 2024</strong>&#160;can be considered. You will be required to upload a covering letter, a brief statement of research interests (describing how past experience and future plans fit with the advertised position), CV and the details of three referees as part of your online application.</div><br> <div>&#160;</div><br> <div>The Department holds an Athena Swan Bronze award, highlighting its commitment to promoting women in Science, Engineering and Technology.</div> </div>