IMMPROVE Postdoctoral Research Assistant

<div xmlns="http://www.w3.org/1999/xhtml"> <p></p><div>We have an exciting opportunity to recruit a highly motivated IMMPROVE Postdoctoral Research Assistant to join our amazing research group led by Dr Nicholas Provine here at the Pandemic Sciences Institute, Nuffield Department of Medicine.</div><br> <div>&#160;</div><br> <div>The Provine Group is a newly established research group in the Pandemic Sciences Institute (physically based within the Centre for Human Genetics) that is focused on unravelling the mechanisms regulating vaccine-induced immune responses &#8211; with focuses on both T cell and B cell responses. Two major focuses in the group are (1) identifying the differential regulation of immunity induced by different vaccine technologies (e.g. viral vectors, mRNA vaccines); (2) utilizing samples from individuals on immunosuppressive medications to identify pathways critical for regulation of vaccine-induced immunity.</div><br> <div>&#160;</div><br> <div>You will be responsible for developing and optimisig a CRISPR-based screening system to manipulate T cell biology in vivo as well as performing in vivo immunization experiments, sample collection, and analysis. You will be tasked with analysing data and preparing reports (written and/or oral) to the group, the university community, and broader scientific audiences. You will also be acting as a source of information and advice to other members of the group on scientific protocols and experimental techniques.</div><br> <div>&#160;</div><br> <div>To be successful in this role, you will hold a PhD/DPhil (or close to completion) in biology, immunology, microbiology, or equivalent along with sufficient specialist knowledge in the discipline to work within established research programmes. You will have experience work with laboratory in vivo tissues and relevant molecular biology skills to develop lentiviral vector/CRISPR systems and experience performing flow cytometry and other project-relevant immune assays. You will also have the ability and experience sharing data and results with colleagues and wider scientific audience.</div><br> <div>&#160;</div><br> <div>Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.</div><br> <div>&#160;</div><br> <div>This position is offered full time on a fixed term contract for 3 years and is funded by the MRC.</div><br> <div>&#160;</div><br> <div>Only applications received before 12 midday on Wednesday 17 July 2024 will be considered. Please quote&#160;<strong>173578</strong>&#160;on all correspondence.</div> </div>