IMMPROVE Postdoctoral Research Assistant

We have an exciting opportunity to recruit a highly motivated IMMPROVE
Postdoctoral Research Assistant to join our amazing research group led by Dr
Nicholas Provine here at the Pandemic Sciences Institute, Nuffield Department
of Medicine.





The Provine Group is a newly established research group in the Pandemic
Sciences Institute (physically based within the Centre for Human Genetics)
that is focused on unravelling the mechanisms regulating vaccine-induced
immune responses – with focuses on both T cell and B cell responses. Two major
focuses in the group are (1) identifying the differential regulation of
immunity induced by different vaccine technologies (e.g. viral vectors, mRNA
vaccines); (2) utilizing samples from individuals on immunosuppressive
medications to identify pathways critical for regulation of vaccine-induced
immunity.





You will be responsible for developing and optimisig a CRISPR-based screening
system to manipulate T cell biology in vivo as well as performing in vivo
immunization experiments, sample collection, and analysis. You will be tasked
with analysing data and preparing reports (written and/or oral) to the group,
the university community, and broader scientific audiences. You will also be
acting as a source of information and advice to other members of the group on
scientific protocols and experimental techniques.





To be successful in this role, you will hold a PhD/DPhil (or close to
completion) in biology, immunology, microbiology, or equivalent along with
sufficient specialist knowledge in the discipline to work within established
research programmes. You will have experience work with laboratory in vivo
tissues and relevant molecular biology skills to develop lentiviral
vector/CRISPR systems and experience performing flow cytometry and other
project-relevant immune assays. You will also have the ability and experience
sharing data and results with colleagues and wider scientific audience.





Applications for this vacancy are to be made online and you will be required
to upload a supporting statement and CV as part of your online application.
Your supporting statement must explain how you meet each of the selection
criteria for the post using examples of your skills and experience.





This position is offered full time on a fixed term contract for 3 years and is
funded by the MRC.





Only applications received before 12 midday on Wednesday 17 July 2024 will be
considered. Please quote **173578** on all correspondence.