Research Assistant in Molecular Medicine

We are seeking a Research Assistant to join the Alsaleh Group based in the
Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and
Musculoskeletal Sciences, University of Oxford. Our research uses primary
human chondrocytes and fibroblasts in 2D and 3D cell culture systems to
investigate age-related changes in senescence and autophagy in the synovium,
which may underpin osteoarthritis. This work will be leveraged to support a
complementary effort aiming to identify new drug targets and develop new
drugs.





As a Research Assistant, you will be following up to validate hits from a
genetic CRISPR screen on regulators of autophagy expression. You will ensure
records of human tissue samples received and processed are up-to-date and
accurate and assist with the analysis of research results. You will also
assist with ordering items for the laboratory and ensuring the laboratory is
stocked and equipped. There will also be opportunities to represent the
research group at external meetings/seminars and contribute to project updates
for funders and in writing journal articles.





You will hold a first degree in a biomedical discipline together with relevant
laboratory experience. You must also have sufficient specialist knowledge in
the discipline to work within our established research programmes, as well as
experience of sequencing or imaging of tissues. Excellent communication
skills, including the ability to write text that can be published, present
data at conferences, and represent the research group at meetings are also
essential. Experience of working with human tissues and culture genetics
techniques is desirable.





This is a full time fixed-term appointment for 6 months.





The closing date for this position is midday on 20/09/2024. You will be
required to upload a supporting statement as part of your online application.