Research Assistant in Evolutionary Microbiology
Applications for this vacancy closed on 22 November 2024 at 12:00PM
We are seeking a Research Assistant for a project testing the ability of phage
to target plasmids associated with antibiotic resistance genes.
Many of the most important antibiotic resistance genes are carried by
conjugative plasmids that transfer resistance across strain and species
boundaries. Pilus-dependent bacteriophage (PDBs) are viruses that infect
bacterial cells via the conjugative pilus, making them a potentially powerful
tool to combat antibiotic resistance in bacterial communities.
The postholder will work on experiments to (1) asses the ability of PDBs to
infect _E.coli_ carrying a panel of reference plasmids, (2) evolving PDBs to
target novel plasmids, and (3) manipulating the genomes of phage and plasmids
using retrons. The postholder will work on these experiments in conjunction
with a post-doc, and will be fully embedded into the lab group.
This position is suitable for researchers with previous experience in
experimental evolution, retron-based genome editing, and qPCR based
quantification assays. You will hold a first degree and have the ability to
manage your own research and administrative activities. Excellent
communication skills, including the ability to write text that can be
published, present data at conferences, and represent the research group at
meetings.
Please send enquiries with CV to craig.maclean@biology.ox.ac.uk
Where Covid-19 has resulted in substantial disruption to your work or research
outputs, please explain this by providing an additional paragraph in your
supporting statement.
The University of Oxford is committed to equality and valuing diversity. All
applicants will be judged on merit, according to the selection criteria.
This post is full time, available from 1 January 2025 onwards for 2 years.
The closing date for applications is 12.00 noon on Friday 22 November 2024,
interviews are likely to be scheduled for mid-December.
Applications for this vacancy are to be made online via our e-recruitment
system, and you will be required to upload a supporting statement and CV as
part of your online application.
to target plasmids associated with antibiotic resistance genes.
Many of the most important antibiotic resistance genes are carried by
conjugative plasmids that transfer resistance across strain and species
boundaries. Pilus-dependent bacteriophage (PDBs) are viruses that infect
bacterial cells via the conjugative pilus, making them a potentially powerful
tool to combat antibiotic resistance in bacterial communities.
The postholder will work on experiments to (1) asses the ability of PDBs to
infect _E.coli_ carrying a panel of reference plasmids, (2) evolving PDBs to
target novel plasmids, and (3) manipulating the genomes of phage and plasmids
using retrons. The postholder will work on these experiments in conjunction
with a post-doc, and will be fully embedded into the lab group.
This position is suitable for researchers with previous experience in
experimental evolution, retron-based genome editing, and qPCR based
quantification assays. You will hold a first degree and have the ability to
manage your own research and administrative activities. Excellent
communication skills, including the ability to write text that can be
published, present data at conferences, and represent the research group at
meetings.
Please send enquiries with CV to craig.maclean@biology.ox.ac.uk
Where Covid-19 has resulted in substantial disruption to your work or research
outputs, please explain this by providing an additional paragraph in your
supporting statement.
The University of Oxford is committed to equality and valuing diversity. All
applicants will be judged on merit, according to the selection criteria.
This post is full time, available from 1 January 2025 onwards for 2 years.
The closing date for applications is 12.00 noon on Friday 22 November 2024,
interviews are likely to be scheduled for mid-December.
Applications for this vacancy are to be made online via our e-recruitment
system, and you will be required to upload a supporting statement and CV as
part of your online application.
| dc:spatial |
Department of Biology, 11a Mansfield Road, Oxford, OX1 3SZ
|
|---|---|
| Subject | |
| oo:contact | |
| oo:organizationPart | |
| vacancy:applicationClosingDate |
2024-11-22 12:00:00+00:00
|
| vacancy:applicationOpeningDate |
2024-11-08 09:00:00+00:00
|
| vacancy:furtherParticulars | |
| vacancy:internalApplicationsOnly |
False
|
| vacancy:salary | |
| type | |
| comment |
We are seeking a Research Assistant for a project testing the ability of phage to target plasmids associated with antibiotic resistance genes. Many of the most important antibiotic resistance genes are carried by conjugative plasmids that transfer resistance across strain and species boundaries. Pilus-dependent bacteriophage (PDBs) are viruses that infect bacterial cells via the conjugative pilus, making them a potentially powerful tool to combat antibiotic resistance in bacterial communities. The postholder will work on experiments to (1) asses the ability of PDBs to infect E.coli carrying a panel of reference plasmids, (2) evolving PDBs to target novel plasmids, ... We are seeking a Research Assistant for a project testing the ability of phage
to target plasmids associated with antibiotic resistance genes. Many of the most important antibiotic resistance genes are carried by conjugative plasmids that transfer resistance across strain and species boundaries. Pilus-dependent bacteriophage (PDBs) are viruses that infect bacterial cells via the conjugative pilus, making them a potentially powerful tool to combat antibiotic resistance in bacterial communities. The postholder will work on experiments to (1) asses the ability of PDBs to infect _E.coli_ carrying a panel of reference plasmids, (2) evolving PDBs to target novel plasmids, and (3) ... |
| label |
Research Assistant in Evolutionary Microbiology
|
| notation |
176470
|
| based near | |
| page |