Postdoctoral Research Associate in Structural Biology

**Pay Scale:** STANDARD RESEARCH GRADE 7



**Salary ( £)**: £38,674 - £46,913 per annum



**Location:** Department of Biochemistry, South Parks Road, Oxford



**Contract type:** Fixed Term Contract for up to 3 years in the first instance



**Hours:** Full Time (37.5 hours per week)





**About the role**





We are seeking to appoint a Postdoctoral Research Associate to join the team
of Prof. Elena Seiradake. The Seiradake group specialises in structural
biology, cell biology and neurobiology, providing access to expertise and
training in these areas. This role will focus on the functions of brain
receptors in nervous system development. The work will involve some or all of
the following methods: single particle cryo-electron microscopy, cryo-electron
tomography, X-ray crystallography, surface plasmon resonance, protein
engineering, mammalian cell culture, fluorescence microscopy, immunostaining.





This full-time fixed-term post is funded by the European Research Council for
up to 3 years in the first instance.





The actual starting salary offered will be based on qualifications and
relevant skills acquired and will also be determined by the funding available.





**What We Offer**





Your happiness and wellbeing at work matters to us, so we offer a range of
family friendly and financial benefits including:





• An excellent contributory pension scheme



• 38 days annual leave



• A comprehensive range of childcare services



• Family leave schemes



• Cycle loan scheme



• Membership to a variety of social and sports clubs



• Discounted bus travel and Season Ticket travel loans





The University also runs an enormous amount of social groups and sports clubs
for those looking for more than just a great place to work.





**About you**





You should hold a PhD/DPhil, or be near completion of a PhD/DPhil, in a
subject area involving structural biology, and have excellent relevant skills
in recombinant protein expression and purification using yeast, bacterial and
HEK293 cell cultures. Experience in the purification of membrane proteins and
mammalian cell cultures is essential, as well as using synthetic polymers,
membrane scaffold proteins and saposin A and nanodisc technology. Experience
in heavy metal transporter protein purification is expected as well as having
experience in cell biology assays involving iPSC-derived cultures and cell
lines using immunostaining and confocal fluorescence microscopy. You will also
have experience in negative stain electron microscopy and sample preparation
for single particle cryogenic electron microscopy. Strong experience using
ATPase activity assays is also essential. You should be well-trained,
enthusiastic and self-motivated, with excellent team-working and interpersonal
skills. You should also have excellent communication skills. You may be
required to travel overseas to conduct collaborative experiments as and when
necessary to advance the research project





**Application Process**





Applications for this vacancy are to be made online via www.recruit.ox.ac.uk
and Vacancy ID **176497**. You will be required to upload your curriculum
vitae and a supporting statement, setting out how you meet the selection
criteria for the post, using examples of your skills and experience. As part
of your application, you will be asked to provide details of two referees and
indicate whether we can contact them now.





For further details, please refer to the How to apply section of the job
description. Any further enquires may be directed to
recruitment@bioch.ox.ac.uk.





The closing date for applications is **12.00 noon** on **Monday 25th November
2024**. Only applications received before this time can be considered.
Interviews for shortlisted candidates to be held on as soon as possible
thereafter.





**Committed to equality and valuing diversity**