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Postdoctoral Research Associate

Applications for this vacancy closed on 24 April 2025 at 12:00PM
The arms race at the plant-pathogen interface is a fascinating field of
biology that can deliver important new, strategies for crop protection. Within
this ERC-funded project, we used chemical proteomics to discover secreted
plant proteins of _Nicotiana benthamiana_ that are manipulated by _Pseudomonas
syringae_ during infection (e.g. Sueldo et al., New Phytol. 2024) and used
artificial intelligence (e.g. Homma et al., Nat. Comm 2023) to predict
pathogen proteins that might be responsible for this manipulation.



This project aims to elucidate the molecular mechanisms underpinning
extracellular manipulation of the host during infection. You will use co-
immunoprecipitation to verify predicted protein-protein interactions and
establish enzymatic assays and activity-based labelling to demonstrate the
effect of target manipulation. You will use reverse genetics to deplete the
components from both plant and pathogen to demonstrate their importance in
pathogen virulence and plant immunity.



We seek an enthusiastic colleague who has extensive experience in molecular
cloning, protein expression and purification and who is keen to collaborate in
an interdisciplinary research team.



Applications for this vacancy are to be made online via our e-recruitment
system. Your supporting statement should explain how to meet each of the
selection criteria for the post using examples of your skills and experience.



Where Covid-19 has resulted in substantial disruption to your work or research
outputs, please explain this by providing an additional paragraph in your
supporting statement.



The University of Oxford is committed to equality and valuing diversity. All
applicants will be judged on merit, according to the selection criteria.



This post is a fixed term, full time position and available immediately. The
closing date for applications is 12.00 noon on 24th April, interviews are
likely to be scheduled for late April/ early May. For further inquiries,
please contact renier.vanderhoorn@biology.ox.ac.uk

dc:spatial
Biology Department, South Parks Road, Oxford, OX1 3RB, you may be relocated to the new Life and Mind Building when it is ready
Subject
oo:contact
oo:organizationPart
vacancy:applicationClosingDate
2025-04-24 12:00:00+01:00
vacancy:applicationOpeningDate
2025-03-27 09:00:00+00:00
vacancy:furtherParticulars
vacancy:internalApplicationsOnly
False
vacancy:salary
type
comment

The arms race at the plant-pathogen interface is a fascinating field of biology that can deliver important new, strategies for crop protection. Within this ERC-funded project, we used chemical proteomics to discover secreted plant proteins of Nicotiana benthamiana that are manipulated by Pseudomonas syringae during infection (e.g. Sueldo et al., New Phytol. 2024) and used artificial intelligence (e.g. Homma et al., Nat. Comm 2023) to predict pathogen proteins that might be responsible for this manipulation.

This project aims to elucidate the molecular mechanisms underpinning extracellular manipulation of the host during infection. You will use co-immunoprecipitation to verify predicted protein-protein interactions ...
The arms race at the plant-pathogen interface is a fascinating field of
biology that can deliver important new, strategies for crop protection. Within
this ERC-funded project, we used chemical proteomics to discover secreted
plant proteins of _Nicotiana benthamiana_ that are manipulated by _Pseudomonas
syringae_ during infection (e.g. Sueldo et al., New Phytol. 2024) and used
artificial intelligence (e.g. Homma et al., Nat. Comm 2023) to predict
pathogen proteins that might be responsible for this manipulation.



This project aims to elucidate the molecular mechanisms underpinning
extracellular manipulation of the host during infection. You will use co-
immunoprecipitation to verify predicted protein-protein ...
label
Postdoctoral Research Associate
notation
178822
based near
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