All vacancies within Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)

There are currently 10 vacancies within Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS):

Title	Closes	Salary
Clinical Trial Manager	Aug. 29, 2018, noon	Grade 7: £31,604 £38,833 p.a.
Personal Assistant	Aug. 29, 2018, noon	Grade 4: £21,585 - £24,983 p.a.
Postdoctoral Research Assistant in Cancer and Vascular Biology	Aug. 29, 2018, noon	Grade 7: Salary in the range £31,604 - £37,706 p.a.
Research Assistant (maternity cover)	Aug. 29, 2018, noon	Grade 6: £28,098 - £33,518 p.a.
Lead Statistician	Sept. 3, 2018, noon	Grade 10: £53,691 - £62,219 p.a.
Research and Administration Assistant	Sept. 3, 2018, noon	Grade 4: £21,585 - £24,983 p.a.
Part-time Laboratory Research Technician	Sept. 5, 2018, noon	Grade 5: £24,983 - £29,799 p.a.
Senior Laboratory Technician	Sept. 10, 2018, noon	Grade 7: £31,604 - £38,833 p.a.
Postdoctoral Researcher in Innate Immunity and Inflammation	Sept. 17, 2018, noon	Grade 7: £31,604 - £38,833 p.a.
Postdoctoral Research Assistant in Fibrosis and Tissue Repair	Sept. 19, 2018, noon	Grade 7: £31,604 - £38,833 p.a.

Clinical Trial Manager

Closes: Aug. 29, 2018, noon; salary: Grade 7: £31,604 £38,833 p.a.

<div> We have an exciting opportunity for a Clinical Trial Manager to join the Surgical Intervention Trials Unit at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, Oxford. As a Clinical Trial Manager your primary responsibility will be to work with the Chief Investigator and the study team to efficiently develop and coordinate the ACL SNNAP clinical trial at a national level. Main duties include organisation and coordination of the study, assistance with developing trial specific documentation, set-up of trial sites, development of data collection processes and liaising with the Clinical Trials Unit to manage the study in accordance with Standard Operating Procedures. You will undertake ongoing project management and overview, and maintain effective communication with all relevant research team members and the funding body. You must have a degree in a biomedical or health related subject. Experience of clinical research methodology, good clinical practice and the research governance framework as well as experience of existing UK clinical research structures, regulatory and ethical systems are essential. High level communication skills, project management experience and evidence of substantial problem solving and team working skills are also essential, as are computer literacy and experience of developing, maintaining and producing information from databases. Previous experience as a trial coordinator/manager and experience of overseeing the conduct of large clinical trials and working to a high standard of Good Clinical Practice are desirable. This is a full-time fixed-term appointment until 30 September 2020. A lower grade offer may be made (Grade 6: £28,098 - £33,518 p.a.) with commensurate reduction in responsibilities (and amendment in job title to Clinical Trial Coordinator) if a suitable candidate cannot be found to fill the Grade 7 position. You will be required to upload a supporting statement and CV as part of your online application. The closing date for this position is 12.00 noon on Wednesday 29 August 2018. </div>

Personal Assistant

Closes: Aug. 29, 2018, noon; salary: Grade 4: £21,585 - £24,983 p.a.

<div> THIS VACANCY IS FOR INTERNAL APPLICANTS ONLY We are seeking a Personal Assistant/Administrative Assistant for Professor David Beard, within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) located at the Botnar Research Centre, Oxford. This post is an exciting opportunity for someone who is keen to work in a varied support role within a research environment. Duties will be wide ranging and will include producing meeting minutes, travel and diary management, as well as assisting with supporting the organisation of events hosted by SITU. Additionally, the role will require providing some administrative support for the Surgical Intervention Trials Unit (SITU) such as: preparing and circulating papers, agendas, minutes and drafting briefing notes as appropriate as well as maintaining, and improving as appropriate, record-keeping and filing systems. You must have the ability to draft correspondence as well as excellent computer skills including: email, Word, Excel and the internet. You must also have a high standard of numeracy. The ability to manage and prioritise a varied and busy workload and work to deadlines is essential. Experience of using financial information systems (e.g. Oracle Financials) or of working in an administrative role within the University of Oxford would be desirable. This is a full-time post for 2 years in the first instance. You will be required to upload a CV and supporting statement as part of your online application. The closing date for this position is 12.00 noon on Wednesday 29 August 2018. </div>

Postdoctoral Research Assistant in Cancer and Vascular Biology

Closes: Aug. 29, 2018, noon; salary: Grade 7: Salary in the range £31,604 - £37,706 p.a.

<div> We are seeking a self-motivated and committed Postdoctoral Research Assistant to join the Kusumbe lab. This project aims to unravel the role of blood vessels and their endothelial cells during metastasis. You will be a member of a young and dynamic research group studying tissue and tumour microenvironments and will provide guidance to less experienced members of the research group, including PhD and project students. You will manage your own academic and administrative activities. This involves small scale project management to co-ordinate multiple aspects of work to meet deadlines as well, and present detailed research proposals to senior researchers. You must have a PhD in molecular/cell biology or a related discipline, together with relevant practical experience. Sufficient specialist knowledge in vascular or bone biology and ability to manage own academic research and associated activities are essential for this post. Willingness to work with the mouse model systems and experience of independently managing a discrete area of a research project would be desirable. This is a full-time appointment fixed-term for 12 months in first instance. Owing to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks: a satisfactory basic Disclosure and Barring Service check and University security screening (eg identity checks) The closing date for applications is 12.00 noon on Wednesday 29 August 2108. </div>

Research Assistant (maternity cover)

Closes: Aug. 29, 2018, noon; salary: Grade 6: £28,098 - £33,518 p.a.

<div> This is an exciting opportunity for a highly motivated and experienced Research Assistant to join the research group of Dr Gillian Farnie at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) based within the Botnar Research Centre, Oxford. The post is funded by the Innovative Medicines initiative (IMI) ULTRA-DD project, a program which aims to create an open access consortium that provides industry with a stream of high quality target-disease associations and tools to study them. The role will require the running of established assays and the development of new cellular assays. As a Research Assistant you will manage your own research and administrative activities, within guidelines provided by senior colleagues. You will be responsible for general laboratory management and administration, including stock control of laboratory consumables. You will develop and contribute to wider project planning, including ideas for new research projects. You will hold a first degree in a relevant area of biological sciences, together with proven experience in academic or industrial laboratories. You will also have experience in general molecular biology techniques and experimentation including: flow cytometry, cloning, QPCR, Western blotting, siRNA, lentiviral techniques. You will have experience and expertise in cell culture and investigating cell biology mechanisms, as well as the ability to work as part of a team and to collaborate with colleagues on a range of projects. Experience in oncology and/or inflammatory diseases, or in a high-throughput environment, would be desirable. This full-time fixed-term post (maternity cover) for 12 months. You will be required to upload a CV and supporting statement as part of your online application. The closing date for this position is 12.00 noon on Wednesday 29 August 2018. </div>

Lead Statistician

Closes: Sept. 3, 2018, noon; salary: Grade 10: £53,691 - £62,219 p.a.

<div> Applications are invited for the position of a Lead Statistician to join the Centre for Statistics in Medicine (CSM) at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), Botnar Research Centre, Oxford. CSM is committed to providing collaborative statistical support for the design, analysis and reporting of clinical research, carries out a methodological research programme and runs training courses. As a Lead Statistician you will provide effective leadership and management by promoting and supporting development of statisticians through mentorship, training and education, you will initiate and implement long-term, often interdisciplinary research programmes as well as manage substantial research resources and budgets. You will lead the integration of the Centre for Statistics in Medicine with other departments across the University by heading statistical collaborations, exchanges, internships and student placements and you will provide statistical leadership and oversight for a portfolio of studies within the Oxford Clinical Trials Research Unit (which is a fully registered UKCRC unit within the Centre for Statistics in Medicine). You will hold a PhD or equivalent in statistics, medical statistics, or other relevant discipline. Experience of managing statistical projects and collaborations as well as substantial experience of clinical trials are essential. Extensive experience of using standard statistical packages, such as STATA, R and SAS and experience of working with complex data sets as well as excellent communication skills with the ability to work well with colleagues, build networks and attract external funding are also essential. Substantial experience of early phase trials, previous experience of trials using adaptive designs and previous supervision of PhD and/or MSc are desirable. This is a full-time fixed-term appointment for 5 years. A lower grade offer may be made (Grade 9: £46,336 - £53,691 p.a.) with commensurate reduction in responsibilities. You will be required to upload a CV and supporting statement as part of your online application The closing date for this position is 12.00 noon on Monday 3 September 2018. Interviews are scheduled to take place on 12 September 2018. </div>

Research and Administration Assistant

Closes: Sept. 3, 2018, noon; salary: Grade 4: £21,585 - £24,983 p.a.

<div> An exciting opportunity has arisen for a pro-active, enthusiastic full-time Research and Administration Assistant to join the Oxford Clinical Trials Research Unit (OCTRU) based within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences at the Botnar Research Centre, Oxford. A key aspect of this role is supporting practical activities and trial activities within the Oxford Clinical Trials Research Unit (OCTRU). Working alongside the group's academics, senior team and quality assurance team, you will be responsible for managing the administration activities of the senior clinical trial unit team. You will be the main point of contact for the Clinical Trials Unit (CTU) and will also ensure delivery of the programme of training provided by the CTU. You will have proven experience of planning and scheduling to ensure complex activities are coordinated, and experience of supporting or coordinating projects or activities. You will have high level administrative and organisational skills with good attention to detail. Experience of working in a Clinical Trial Unit would be desirable. This is a full-time fixed-term appointment for 2 years in the first instance. You will be required to upload a supporting statement and CV as part of your online application. The closing date for this position is 12.00 noon on 3 September 2018. Interviews are expected to be held on 11 September 2018. </div>

Part-time Laboratory Research Technician

Closes: Sept. 5, 2018, noon; salary: Grade 5: £24,983 - £29,799 p.a.

<div> We are seeking a Laboratory Research Technician to join the Clinical Translation team in the Arthritis Research UK Centre for OA Pathogenesis at the Kennedy Institute of Rheumatology. You will be working on a project which sets out to discover whether there are molecular endotypes (subgroups) in OA. Work is planned in an international consortium (STEp-UP OA) accessing synovial fluid collected from around 2000 patients with various stages of OA and preparing them to be analysed for ~5000 proteins by aptameric array analysis with a commercial partner, with subsequent bioinformatics analysis and validation work in our laboratory to examine for evidence of endotypes. The role is responsible for the laboratory aspects of successful delivery of this study, and any related work being carried out within the Centre during this time. You will have previous laboratory experience, including handling human samples and a BSc/MSc in biological science or equivalent is desirable. Excellent communication, computing and organisational skills are essential to the post, as well as strong attention to detail, with the ability to catalogue samples and record results in a clear and organised fashion. This is a part-time (0.6FTE) fixed-term appointment for 1 year in the first instance. Owing to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks: a satisfactory basic Disclosure and Barring Service check You will be required to upload a supporting statement and CV as part of your online application. The closing date for applications is 12.00 noon on Monday 3 September 2018. </div>

Senior Laboratory Technician

Closes: Sept. 10, 2018, noon; salary: Grade 7: £31,604 - £38,833 p.a.

<div> We are looking for an enthusiastic and experienced Senior Laboratory Technician to join the new research group of Dr Anjali Kusumbe at the Kennedy Institute of Rheumatology in Oxford to ensure the smooth running of the laboratory through supporting and undertaking experiments in cell biology. You will process mouse and human tissues undertaking primary cell isolation, quantifying gene and protein expression using a range of state-of-the-art technologies including immunohistochemistry, flow and mass-spec cytometry and gene expression analysis. You will contribute to general laboratory maintenance, e.g. maintain stocks and order laboratory supplies and consumables. You will also have responsibilities in developing new scientific techniques and experimental protocols and ensuring all necessary SOPs are up-to-date and available. You should have an MSc in biological sciences, preferably in cellular biology together with considerable previous laboratory experience. Ability to write up experimental results and strong attention to detail is essential. You should have the ability to organise your own work load and a conscientious and enthusiastic working approach. Experience in training individuals in laboratory techniques or supervisory experience would be desirable. Owing to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks: a satisfactory basic Disclosure and Barring Service check and a University security screening (eg identity checks). This is a full-time post funded for 1 year in the first instance. The closing date for applications is 12.00 noon on Monday 10 September 2018. </div>

Postdoctoral Researcher in Innate Immunity and Inflammation

Closes: Sept. 17, 2018, noon; salary: Grade 7: £31,604 - £38,833 p.a.

<div> We are seeking a highly motivated, academically excellent and proactive Postdoctoral Researcher with a strong background in innate immunity to join the Genomics of Inflammation group of Professor Irina Udalova at the University of Oxford. You will be carrying out research on the transcriptional and molecular control of pathogenic interactions between myeloid cells in inflammatory tissue microenvironment, within a new leading-edge programme funded by the Wellcome Trust. You will be using unique in vivo models, advanced immunological and imaging approaches and innovative single cell technologies. You will be based at the Kennedy Institute of Rheumatology, University of Oxford, which is a world-leading research centre where discovery research drives development of transformative therapies for chronic inflammatory and degenerative disease. You will benefit from intellectually stimulating vibrant international research environment and outstanding support facilities. You will hold a PhD (or near completion) in immunology, molecular and cellular biology, or similar. You will demonstrate capacity to deliver high quality research outputs, illustrated by a strong publication record in high profile immunological journals. Expertise in neutrophil and/or macrophage biology, advanced imaging techniques or in vivo models of cell tracking would be desirable. Please direct your informal enquiries to Professor Irina Udalova: <a rel="nofollow" href="mailto:Irina.udalova@kennedy.ox.ac.uk">Irina.udalova@kennedy.ox.ac.uk</a>. This is a full-time appointment fixed-term for 3 years with a strong possibility of extension for a further 2 years. Owing to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks: a satisfactory basic Disclosure and Barring Service check; University security screening (eg identity checks) You will be required to upload a supporting statement and CV as part of your online application. The closing date for applications is 12.00 noon on Monday 17 September 2018. </div>

Postdoctoral Research Assistant in Fibrosis and Tissue Repair

Closes: Sept. 19, 2018, noon; salary: Grade 7: £31,604 - £38,833 p.a.

<div> We are seeking a highly motivated and proactive Postdoctoral Research Assistant in Fibrosis and Tissue Repair to join the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), based at the Kennedy Institute of Rheumatology, Oxford. As a Postdoctoral Research Assistant in Fibrosis and Tissue Repair you will undertake research projects, investigating mechanisms of fibrotic disease pathogenesis. You will carry out flow cytometry, Western blot, ELISA, qPCR, cell culture, confocal microscopy, ChIP-Seq and RNS-Seq. You will also contribute to the smooth running of the groups laboratory facilities, participate in laboratory meetings, training and organisation and maintain a database of patient samples collected in accordance with ethics and the HTA. You will hold a PhD in the relevant field and/or higher degree in medicine. Strong time and project management skills, assay development and the ability to carry out Western blot, FACS, qPCR, cell culture and confocal microscopy are essential, as is advance computer skills, especially with regards to data presentation and analysis software packages. Understanding of fibrotic diseases and Understanding of signal transduction mechanisms/epigenetic control of gene expression are desirable. This is a full-time fixed-term appointment until February 2020. Owing to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks: a satisfactory basic Disclosure and Barring Service check You will be required to upload a CV and supporting statement as part of your online application. The closing date for this position is 12.00 noon on Wednesday 19 September 2018. </div>