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All vacancies within Nuffield Department of Clinical Neurosciences
There are currently 5 vacancies within Nuffield Department of Clinical Neurosciences:
| Title | Closes | Salary |
|---|---|---|
| Laboratory Technician | March 28, 2025, noon | Standard Grade 5: £31,459 – £36,616 per annum |
| Postdoctoral Research Associate: Neurophysiologist | March 28, 2025, noon | Research Grade 7: £38,674 – £45,628 per annum A less experienced candidate may be appointed at Research Grade 6 (£34,982 to £40,855) per annum, with a commensurate adjustment in either the essential criteria, responsibilities or duties. |
| DREaMED Programmer | March 31, 2025, noon | Research Grade 7: £38,674 – £46,913 per annum |
| Postdoctoral Research Scientist | April 9, 2025, noon | Research Grade 7: £38,674 - £46,913 |
| Postdoctoral Researcher | April 28, 2025, noon | Research Grade 7: £38,674 - £46,913 |
Laboratory Technician
Closes: March 28, 2025, noon; salary: Standard Grade 5: £31,459 – £36,616 per annum
<div> <p></p><div>Professor Robert MacLaren invites experienced laboratory technicians to apply for an available post providing technical support for his biomedical research programme.</div><br> <div> </div><br> <div>Applicants must hold a relevant qualification in science and have experience of working in a biomedical laboratory, good IT skills (including proficiency in Word, Excel and PowerPoint) and a knowledge of Health and Safety regulations. The ability to troubleshoot technical problems, record data meticulously and present experimental results in a clear manner is essential. You will be part of a team but are also expected to work independently. Prior experience of working collaboratively within a research team is highly desirable, and a background in animal research would be advantageous.</div><br> <div> </div><br> <div>Please see the ‘Job Description’ for further details on the role, responsibilities, and selection criteria, as well as further information about the university and how to apply.</div><br> <div> </div><br> <div><strong>This post is full time (36.5 hours per week) and fixed term until 31st March 2026.</strong></div><br> <div> </div><br> <div><strong>Only applications received before midday 12:00 on Friday 28th March will be considered.</strong></div><br> <div> </div><br> <div><strong>Interviews will be held as soon as possible thereafter.</strong></div> </div>Postdoctoral Research Associate: Neurophysiologist
Closes: March 28, 2025, noon; salary: Research Grade 7: £38,674 – £45,628 per annum A less experienced candidate may be appointed at Research Grade 6 (£34,982 to £40,855) per annum, with a commensurate adjustment in either the essential criteria, responsibilities or duties.
<div> <p></p><div>We are seeking a neuroscientist with a strong background in visual and/or circadian biology to work as part of the Sleep and Circadian Neuroscience Institute (SCNi) within the Nuffield Department of Clinical Neurosciences (NDCN). The research interests of the SCNi are to: (A) Understand the neural mechanisms that generate and regulate sleep and circadian biology (B) Define the mechanistic links between sleep/circadian rhythm disruption and disorders of the central nervous system and © Apply this knowledge for the development of evidence-based clinical interventions.</div><br> <div> </div><br> <div>The successful candidate will be responsible for leading a specific research project entitled ‘<strong><em>Investigating the multiple roles of cryptochromes in animal magnetoreception</em></strong>’ which will be based within the SCNi. They will work closely with Prof Stuart Peirson ( <a rel="nofollow" href="http://">https://www.ndcn.ox.ac.uk/team/stuart-peirson</a>) and Mark Hankins ( <a rel="nofollow" href="http://">https://www.ndcn.ox.ac.uk/team/mark-hankins</a>).  This project is part of a Wellcome Discovery Award, in collaboration with the University of Leicester (Profs Ezio Rosato, Bambos Kyriacou), Manchester (Prof Richard Baines) and the National Physics Laboratory (Dr Alex Jones).</div><br> <div> </div><br> <div>Many species, including humans, are reported to be magnetosensitive. Indeed, some animals navigate using the weak magnetic field (MF) of Earth. Others do not, but there are accounts of MF effects and the concern that exposure to low frequency MFs may affect health. Whether the same or different mechanisms may be involved, is currently unknown.</div><br> <div> </div><br> <div>One mechanism has acquired experimental prominence. Cryptochromes (CRYs), best known for their role in circadian rhythmicity, may mediate magnetosensitivity via a photochemical quantum reaction involving CRY-bound flavin adenine dinucleotide (FAD) and a chain of tryptophan residues within CRY that generate a radical pair (RP). Unexpectedly, we have demonstrated that the CRY C-terminal (CRY-CT), without the canonical FAD binding site or tryptophan chain, elicits behavioural and cellular responses to MFs in Drosophila melanogaster. Our results do not necessarily contradict the RP model but urge a fundamental revision of its canonical interpretation. We propose a multidisciplinary programme of work examining each level of the sensory chain, including detection, signal transduction and amplification, cellular and behavioural responses. Our combined expertise includes quantum physics, computational chemistry, protein biophysics, electrophysiology, molecular genetics, and behaviour. We are thus uniquely positioned to address and move towards solving this fascinating and fundamental biological question.</div><br> <div> </div><br> <div>Laboratory work will involve the use of electrophysiological, transgenic and behavioural techniques including multielectrode array electrophysiology, activity monitoring and behavioural testing. Experience in the analysis of complex datasets is essential. The candidate must have or be close to completing a Phd/DPhil. A Home Office Licence (A-C) or equivalent experience would be an advantage. The post holder will be expected to contribute to the training and mentoring of some junior staff.</div><br> <div> </div><br> <div><strong>The post is full time for a fixed term until 31st December 2028 in the first instance.</strong></div><br> <div> </div><br> <div><strong>Only applications received before 12.00 midday on Friday 28th March will be considered.</strong></div><br> <div> </div><br> <div><strong>Interviews will be held as soon as possible thereafter. </strong></div> </div>DREaMED Programmer
Closes: March 31, 2025, noon; salary: Research Grade 7: £38,674 – £46,913 per annum
<div> <p></p><div>The University of Oxford provides a stimulating work environment, renowned globally as a centre of excellence. Our research addresses key global challenges, from combating climate change to developing life-saving vaccines.</div><br> <div> </div><br> <div>We have an exciting opportunity available to join the Nuffield Department of Clinical Neurosciences as Programmer for the DREaMED project, based at the John Radcliffe. This is an opportunity to join a growing research team deploying machine learning solutions into health care.</div><br> <div> </div><br> <div><strong>About the Role</strong></div><br> <div>The post holder will join an exciting project – DREaMED (Defining, Recognising and Escalating Maternal Early Deterioration): Decreasing inequality through improved outcomes.</div><br> <div> </div><br> <div>The post holder will work with clinical researchers and the OUH Senior DREaMED Programmer to develop software aimed at clinical use and clinical research. The post holder will join the Critical Care Research Group (CCRG), led by Professor Peter Watkinson. The CCRG undertakes a programme of research focussed on the early identification of patient deterioration and long-term outcomes of patients admitted to Intensive Care Units. The CCRG group specialises in analysing large routine datasets to develop predictive models in patients with critical illness. We aim to provide novel insights to improve clinical practice and guide the design of large-scale randomised controlled trials.</div><br> <div> <br> <br> </div><br> <div><strong>About You</strong></div><br> <div>We are seeking an experienced and enthusiastic programmer with a strong passion for wanting to improve health care outcomes.</div><br> <div>Proficiency in at least one general purpose programming language (e.g., Python, JavaScript, Java) and a basic understanding of others.</div><br> <div>Full stack development experience (working with both front-end and back-end technologies).</div><br> <div>Excellent communication skills and the ability to engage with stakeholders across academic and administrative spheres are crucial.</div><br> <div> <br> <br> </div><br> <div><strong>What We Offer</strong></div><br> <div>As an employer, we genuinely care about our employees’ wellbeing and this is reflected in the range of benefits that we offer including:</div><br> <div>An excellent contributory pension scheme, Hybrid working, with 3 days a week for in-office collaboration, 38 days annual leave, A comprehensive range of childcare services, Family leave schemes, Cycle loan scheme, Discounted bus travel and Season Ticket travel loans, Membership to a variety of social and sports clubs etc.</div><br> <div> <br> <br> </div><br> <div><strong>Application Process</strong></div><br> <div>Please see the below 'Job Description' for further details on the responsibilities and selection criteria, as well as further information about the university and how to apply.  You will be required to upload a covering letter/supporting statement, CV and the details of two referees as part of your online application.</div><br> <div> <br> <br> </div><br> <div><strong>The post is full time for a fixed term until 31st March 2028 in the first instance.</strong></div><br> <div> </div><br> <div><strong>Only applications received before 12.00 midday on Monday 31st March 2025 will be considered.</strong></div><br> <div> </div><br> <div><strong>Interviews will be held on Wednesday 23rd April. </strong></div> </div>Postdoctoral Research Scientist
Closes: April 9, 2025, noon; salary: Research Grade 7: £38,674 - £46,913
<div> <p></p><div> </div><br> <div>AN EXCITING OPPORTUNITY TO JOIN A MULTIDISCIPLINARY RESEARCH TEAM AT THE OXFORD CENTRE FOR NEUROINFLAMMATION</div><br> <div> </div><br> <div>You are invited to apply to join Professor Lars Fugger and his team at the University of Oxford, based at the Weatherall Institute of Molecular Medicine, John Radcliffe Hospital. You will join a team of research scientists, computational biologists, and clinicians, have access to state-of-the-art technologies and collaborate with leading researchers both locally and globally.</div><br> <div> </div><br> <div>Physical and mental disability caused by the immune system is a common clinical occurrence in many diseases of the brain, most notably for patients with multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD) and MOG antibody disease (MOGAD). However, the role of immune cells in patients afflicted by these diseases is largely unknown, thereby limiting our ability to develop better and safer treatment options. As part of a highly collaborative research initiative, the successful applicant will perform a diverse range of experimental assays that rely on a strong understanding of cellular and molecular biology.</div><br> <div> </div><br> <div>Applicants must hold a PhD/ D.Phil in Immunology or Neuroimmunology. You must have experience working with primary cells and/or patient tissue and be highly motivated to learn and develop new techniques that interrogate the function of cells in a disease setting.</div><br> <div> </div><br> <div>Please see the below 'Job Description' for further details on the responsibilities and selection criteria, as well as further information about the university and how to apply.</div><br> <div> </div><br> <div>This is a highly competitive position and therefore it is advisable to contact Professor Lars Fugger prior to making a formal application in order to discuss the role. If you would like to discuss your application informally before applying, please email Professor Fugger ( <a rel="nofollow" href="http://">lars.fugger@ndcn.ox.ac.uk</a>).</div><br> <div> </div><br> <div><strong>The post is full time for a fixed term of 3 years in the first instance.</strong></div><br> <div> </div><br> <div><strong>Only applications received before 12.00 midday on Wednesday 9th April will be considered.</strong></div><br> <div> </div><br> <div><strong>Interviews will be held as soon as possible thereafter. </strong></div> </div>Postdoctoral Researcher
Closes: April 28, 2025, noon; salary: Research Grade 7: £38,674 - £46,913
<div> <p></p><div>We are seeking a <strong>Postdoctoral Research Assistant</strong> to run exercise studies on healthy volunteers and on patients with breathing difficulties.  We are using immersive virtual reality to manipulate the cycling experience.  The post is based in Oxford, and would be suitable for someone who is happy to be physically present in the laboratory for most of the week. The studies are a continuation of those described in this manuscript: <a rel="nofollow" href="http://">https://www.biorxiv.org/content/10.1101/2022.06.16.496494v1 </a></div><br> <div> </div><br> <div>Your duties will include managing your own research, running research experiments, contributing to the design of research materials and analysing and presenting qualitative and/or quantitative data from a variety of sources.</div><br> <div> </div><br> <div>The successful candidate will hold a PhD degree in a relevant topic (e.g. Biomedical sciences), have good organisational and communication skills and have experience running research studies in humans. Experience with data analysis and basic experience using programming languages (e.g. R, Python, Unity, Matlab) is desirable.</div><br> <div> </div><br> <div>Potential applicants are very welcome to discuss the role with Kyle Pattinson, the PI at <a rel="nofollow" href="http://">kyle.pattinson@nda.ox.ac.uk </a></div><br> <div> </div><br> <div><strong>The post is full time for a fixed term of 12 months in the first instance.</strong></div><br> <div> </div><br> <div><strong>Only applications received before 12.00 midday on Monday 28th April will be considered. </strong></div><br> <div> </div><br> <div><strong>Interviews will be held Wednesday 21st May. </strong></div> </div>