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Vacancies within Nuffield Department of Surgical Sciences

There are currently 2 vacancies within Nuffield Department of Surgical Sciences:

Title Closes Salary
Postdoctoral Researcher in Translational Research Immunology Feb. 12, 2023, noon Standard Grade 7: Grade7: £34,308 - £42,155 per annum
Senior Clinical Research Fellow in Organ Retrieval and Vascular Access Surgery Feb. 13, 2023, noon Grade E82: £88,364 - £119,133 per annum

Postdoctoral Researcher in Translational Research Immunology

Closes: Feb. 12, 2023, noon; salary: Standard Grade 7: Grade7: £34,308 - £42,155 per annum

<div> <p></p><div><strong>Contract type: Fixed term for 12 months</strong></div><br> <div><strong>Hours: Full-time</strong></div><br> <div>&#160;</div><br> <div><strong>About the role</strong></div><br> <div>You will work on a new, translational project, funded by the MRC Confidence in Concept fund and industry partner, Oxford Biomedica, to generate antigen-specific, human regulatory B cells (Breg). You will be responsible for the development and implementation of lentiviral platforms and CRISPR/Cas9 techniques to deliver genes encoding B cell receptor constructs to primary human B cells. Successful realisation of this project will demonstrate proof of concept design of precision B cell therapies in transplantation and immune-mediated disorders. You will be based within the Nuffield Department of Surgical Sciences in the John Radcliffe Hospital, as your normal place of work.</div><br> <div>&#160;</div><br> <div>This position offers a unique opportunity to contribute to the work of an internationally recognised team of scientists and clinicians within the Translational Research Immunology Group (TRIG). TRIG has extensive experience in studying and translating regulatory cell therapy from the bench to the bedside as new treatments for transplant recipients. Breg have been shown to have key roles in defining outcomes in organ transplantation and autoimmune disease. TRIG has developed new methods of expanding human Breg in vitro, to enable in depth study and therapeutic development.</div><br> <div>&#160;</div><br> <div><strong>About you</strong></div><br> <div>You will hold a PhD (or be near to completion: thesis submitted) in a relevant area such as cellular or molecular biology at the time of application.&#160;Experience with genetic editing techniques such as vector manufacture, viral transfection, PCR and sequencing is desirable but not essential. You will have demonstrated the ability to work independently within projects, with the ability to communicate results clearly and succinctly in presentations, manuscripts and grant applications.</div><br> <div>&#160;</div><br> <div>This position is available from February 2023, fixed-term for 12 months and is funded by the Medical Research Council Confidence in Concept &amp; Oxford Biomedica.</div><br> <div>&#160;</div><br> <div><strong>Application Process</strong></div><br> <div>If you would like to discuss this role, please contact the Human Resources team on recruitment@nds.ox.ac.uk.</div><br> <div>&#160;</div><br> <div>Applications for this vacancy are to be made online. You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application. Please quote reference NDSA876B on all correspondence.</div><br> <div>&#160;</div><br> <div>Only applications received before noon on Monday 13 February 2023 can be considered.</div><br> <div>&#160;</div><br> <div>Interviews will be held weeks commencing Thursday 23 February 2023.</div><br> <div>&#160;</div><br> <div><strong>Committed to equality and valuing diversity</strong></div> </div>

Senior Clinical Research Fellow in Organ Retrieval and Vascular Access Surgery

Closes: Feb. 13, 2023, noon; salary: Grade E82: £88,364 - £119,133 per annum

<div> <p></p><div><strong>Contract type: Fixed term for 36 months</strong></div><br> <div><strong>Hours: Full-time</strong></div><br> <div>&#160;</div><br> <div><strong>About the role</strong></div><br> <div>We are looking for an Academic Surgeon to work in our Transplant team based at the Churchill and the John Radcliffe Hospitals in Headington, Oxford. The department has a strong track record in transplant immunology with an emerging programme in cell therapy. The successful candidate will be expected to run an active laboratory programme and to play a leading role in the translation of novel cell-based therapies into clinical practice.</div><br> <div>&#160;</div><br> <div>The post-holder will be required to participate in programmes for teaching clinical students, training junior doctors and in clinical examinations. They will also participate in clinical governance activities, including clinical audit, clinical effectiveness, risk management and quality improvement activates as required by the Trust and external accrediting bodies. The post-holder also will be required to keep himself/herself fully up-to-date with their relevant area of practice and to be able to demonstrate this to the satisfaction of the Trust.</div><br> <div>&#160;</div><br> <div><strong>About you</strong></div><br> <div>You will be qualified to FRCS or equivalent with CCT in General/Transplant Surgery. You will also hold a GMC registration with a licence to practice. A Higher Medical Degree (MD/PhD) or equivalent is essential.</div><br> <div>&#160;</div><br> <div>You will have completed training in abdominal transplant, vascular access and organ retrieval surgery and will have experience in the delivery of abdominal organ transplantation and vascular access.</div><br> <div>&#160;</div><br> <div>Additionally you will have excellent communication and interpersonal skills as well as administrative and time management skills, with a good track record in internationally leading research in transplantation with peer reviewed publications.</div><br> <div>&#160;</div><br> <div>This full-time post is available immediately and is fixed term for 36 months.</div><br> <div>&#160;</div><br> <div><strong>Application Process</strong></div><br> <div>If you would like to discuss this role, please contact Prof Peter J Friend via email: peter.friend@nds.ox.ac.uk</div><br> <div>&#160;</div><br> <div>Applications for this vacancy are to be made online. You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application. Please quote reference NDSA888 on all correspondence.</div><br> <div>&#160;</div><br> <div>Only applications received before noon Monday 13 February 2023 can be considered.</div><br> <div>&#160;</div><br> <div>Interviews will be held 22 February 2023.</div><br> <div>&#160;</div><br> <div><strong>Committed to equality and valuing diversity</strong></div><br> <div>&#160;</div> </div>